PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus PRP4 YAP1802 11283351 i2d,mint,intact,dip exp PRP4 MDJ1 11805837 dip exp HSP82 PRP4 11805837 dip exp SSB1 PRP4 16429126 intact exp GFA1 PRP4 11805837 dip exp HSP60 PRP4 11805837 dip exp ENO1 PRP4 11805837 dip exp PRP4 RPS0B 16429126 intact exp PRP4 GIS2 21232131 biogrid exp PRP4 YRA1 17922018 biogrid exp PRP4 CHC1 11805837 dip exp SSA1 PRP4 10606269,16429126 biogrid,intact exp LEU2 PRP4 11805837 dip exp PRP4 SPP382 i2d exp HTA2 PRP4 21179020 intact exp PRP4 SCJ1 11805837 dip exp PRP4 RPA49 16554755 biogrid,i2d,mint,intact exp MET6 PRP4 11805837 dip exp ATP2 PRP4 11805837 dip exp PRP4 FOL1 16429126 intact exp PRP4 SLF1 i2d exp PRP4 HSP42 11805837 dip exp PRP4 JSN1 11283351 i2d,mint,intact,dip exp PRP4 ERR3 i2d exp STI1 PRP4 11805837 biogrid,mint,intact,dip exp PRP4 LHP1 16554755 biogrid,i2d,mint,intact exp PRP4 CBC2 24500206 biogrid exp HSP26 PRP4 11805837 dip exp PDC1 PRP4 11805837 dip exp PRP4 MSH3 16429126 intact exp PRP4 CDC48 11805837 dip exp, ortho PRP4 CRM1 26673895 biogrid exp, ortho PRP4 LSM2 16429126,16554755, 23023127 biogrid,i2d,mint,intact exp, ortho, pred PRP4 BRR2 14759368,18953335,16429126,10449419,25670679,11720284,16554755,10377396, 23023127 biogrid,i2d,mint,intact,dip exp, ortho, pred PRP4 DIB1 23023127 i2d exp, ortho, pred PRP4 SNU13 16554755, 23023127 biogrid,i2d,mint,intact exp, ortho, pred PRP4 SME1 11805826,16429126, 23023127 biogrid,mint,intact,dip exp, ortho, pred PRP4 PRP4 11805826, 23023127 mint,intact exp, ortho, pred PRP4 PRP8 16373487,11805826,16429126, 23023127 biogrid,mint,intact,dip exp, ortho, pred PRP4 LSM7 11805826,16429126,10900456, 23023127 biogrid,i2d,mint,intact,dip exp, ortho, pred PRP4 SNU114 11805826,16429126, 23023127 biogrid,i2d,mint,intact,dip exp, ortho, pred PRP4 PRP21 16429126, 23023127 biogrid,i2d,intact exp, pred PRP4 SAS10 16554755, 23023127 biogrid,i2d,mint,intact exp, pred PRP4 MPP10 16554755, 23023127 biogrid,i2d,mint,intact exp, pred PRP6 PRP4 11805826,16429126,16554755,8146658,11805837, 23023127 biogrid,i2d,mint,intact,dip exp, pred PRP4 GAR1 16554755, 23023127 biogrid,i2d,mint,intact exp, pred PRP9 PRP4 23023127 i2d exp, pred PRP4 PRP3 9826507,14759368,11805826,16429126,11283351,18719252, 23023127 biogrid,i2d,mint,intact,dip exp, pred PRP4 SNU66 11805826,16429126,21614000, 23023127 biogrid,i2d,mint,intact,dip exp, pred PRP4 LEA1 21558325, 23023127 biogrid,i2d exp, pred PRP4 SPP381 11805826,16429126, 23023127 biogrid,mint,intact,dip exp, pred PRP4 SMX2 11805826,16429126, 23023127 biogrid,mint,intact,dip exp, pred PRP4 SMD3 10377396, 23023127 i2d,dip exp, pred PRP4 LSM6 16429126,16554755, 23023127 biogrid,i2d,mint,intact exp, pred PRP4 NOP56 16554755, 23023127 biogrid,i2d,mint,intact exp, pred PRP4 PRP31 11805826,16429126,16554755, 23023127 biogrid,i2d,mint,intact,dip exp, pred PRP4 RRP9 16554755, 23023127 biogrid,i2d,mint,intact exp, pred PRP4 RRP36 16554755, 23023127 biogrid,i2d,mint,intact exp, pred NOP1 PRP4 16554755, 23023127 biogrid,i2d,mint,intact exp, pred PRP4 LSM4 16429126, 23023127 biogrid,i2d,intact exp, pred PRP4 PRP19 11804584,11842115, 23023127 biogrid,i2d exp, pred PRP4 BUD21 16554755, 23023127 biogrid,i2d,mint,intact exp, pred PRP4 LSM8 16429126,10747033,10900456,23560879, 23023127 biogrid,i2d,mint,intact,dip exp, pred PRP4 NAN1 16554755, 23023127 biogrid,i2d,mint,intact exp, pred PRP4 AAR2 16429126, 23023127 i2d,intact exp, pred PRP4 RSE1 23023127 i2d exp, pred PRP4 SMD2 16554755, 23023127 biogrid,i2d,mint,intact exp, pred PRP4 CUS1 23023127 i2d exp, pred PRP4 HSH155 23023127 i2d exp, pred PRP4 ARP2 11805837, 23023127 biogrid,mint,intact,dip exp, pred PRP4 LSM5 11805826,16429126, 23023127 biogrid,mint,intact,dip exp, pred GCN2 PRP4 11805826,16429126, 23023127 biogrid,mint,intact,dip exp, pred PRP4 SNU23 11805826,16429126, 23023127 biogrid,i2d,mint,intact,dip exp, pred PRP4 SMB1 16429126,21558325,16554755, 23023127 biogrid,i2d,mint,intact exp, pred PRP4 UTP8 16554755, 23023127 biogrid,i2d,mint,intact exp, pred PRP4 PRP2 16554755, 23023127 biogrid,i2d,mint,intact exp, pred PRP4 NHP2 11805826,16429126, 23023127 biogrid,mint,intact,dip exp, pred PRP4 NOP58 16554755, 23023127 biogrid,i2d,mint,intact exp, pred PRP4 LSM3 14759368,16429126,10747033,19740761, 23023127 biogrid,mint,intact,dip exp, pred PRP4 SMD1 23023127 i2d exp, pred PRP4 SMX3 11805826,16429126,16554755, 23023127 biogrid,i2d,mint,intact,dip exp, pred PRP4 DPH1 ortho PRP4 Uncharacterized membrane protein YML131W ortho TCP1 PRP4 ortho PRP4 CCT7 ortho PRP4 LAP2 ortho PRP4 CCT3 ortho PRP4 PAC10 ortho PRP4 GIM5 ortho PRP4 CCT2 ortho PRP4 CCT6 ortho PRP4 CCT4 ortho PRP4 PRP43 ortho PRP4 CCT5 ortho PRP4 CCT8 ortho PRP4 PRP46 23023127 ortho, pred PRP4 LSM1 23023127 ortho, pred PRP4 PRP39 23023127 pred PRP4 SNU71 23023127 pred PRP4 PRP38 23023127 pred PRP4 PRP40 23023127 pred PRP4 PFS2 23023127 pred PRP4 SOF1 23023127 pred PRP4 CDC40 23023127 pred PRP4 CIA1 23023127 pred PRP4 CAC2 23023127 pred PRP4 MSL5 23023127 pred PRP4 PRP11 23023127 pred PRP4 NPL3 23023127 pred PRP4 MET30 23023127 pred PRP4 SWD2 23023127 pred PRP4 CDC20 23023127 pred MSI1 PRP4 23023127 pred PRP4 PRP28 23023127 pred PRP4 PRP5 23023127 pred PRP4 PRP24 23023127 pred

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P20053 - 11805826 - C 25 P20053 - 11805826 - C 10 P20053 - 11805837 - C 3 P20053 - 11805837 - C 3 P20053 - 11805826 - C 34 Q03338 P20053 - 10377396,10449419,11283351,11720284,11804584,11805826,9826507 - X 2 Q03338 P20053 - 11283351 - X 2 P47135 P20053 - 11283351 - X 2 P20053 - 11805826 - C 7 P20053 - 11805826 - C 16 P20053 - 11805826 - C 7 P20053 - 11805826 - C 22 P20053 - 14759368 - C 14 P20053 - 11805826 - C 18 P20053 - 11805826 - C 28 P20053 - 11805826 - C 16 P20053 - 11805826 - C 8 P20053 - 10900456 - X 2 Q12420 P20053 - 10449419 - X 2 P47093 P20053 - 10900456 - X 2 P53309 P20053 - 11283351 - X 2 P15442 P20053 affinity chromatography technology 16429126 physical association X 2 P15442 P20053 affinity chromatography technology 11805826 physical association X 2 P40204 P20053 affinity chromatography technology 11805826 physical association X 2 P53207 P20053 affinity chromatography technology 17200106 physical association X 2 P49704 P20053 affinity chromatography technology 16554755 physical association X 2 P49704 P20053 affinity chromatography technology 16429126 physical association X 2 P49704 P20053 affinity chromatography technology 16429126 physical association X 2 P49704 P20053 affinity chromatography technology 17200106 physical association X 2 P49704 P20053 affinity chromatography technology 11805826 physical association X 2 P49704 P20053 affinity chromatography technology 11805826 physical association X 2 Q06506 P20053 affinity chromatography technology 16554755 physical association X 2 Q00723 P20053 affinity chromatography technology 17200106 physical association X 2 P33334 P20053 affinity chromatography technology 16429126 physical association X 2 P33334 P20053 affinity chromatography technology 16429126 physical association X 2 P33334 P20053 affinity chromatography technology 16373487 physical association X 2 P33334 P20053 affinity chromatography technology 17200106 physical association X 2 P33334 P20053 affinity chromatography technology 11805826 physical association X 2 P32381 P20053 affinity chromatography technology 11805837 physical association X 2 P19736 P20053 affinity chromatography technology 17200106 physical association X 2 Q08920 P20053 affinity chromatography technology 24500206 physical association X 2 P40070 P20053 affinity chromatography technology 16429126 physical association X 2 P40070 P20053 affinity chromatography technology 17200106 physical association X 2 P33399 P20053 affinity chromatography technology 16554755 physical association X 2 P49955 P20053 affinity chromatography technology 17200106 physical association X 2 Q06819 P20053 affinity chromatography technology 17200106 physical association X 2 Q12136 P20053 affinity chromatography technology 16554755 physical association X 2 P32523 P20053 affinity chromatography technology 11842115 physical association X 2 P32523 P20053 biochemical 11804584 association X 2 P32495 P20053 affinity chromatography technology 11805826 physical association X 2 Q01080 P20053 affinity chromatography technology 16554755 physical association X 2 Q03338 P20053 pull down 9826507 direct interaction X 2 Q03338 P20053 two hybrid 9826507 direct interaction X 2 Q03338 P20053 two hybrid 9826507 direct interaction X 2 Q03338 P20053 affinity chromatography technology 16429126 physical association X 2 Q03338 P20053 affinity chromatography technology 16429126 physical association X 2 Q03338 P20053 affinity chromatography technology 17200106 physical association X 2 Q03338 P20053 two hybrid 11283351 direct interaction X 2 Q03338 P20053 two hybrid 18719252 direct interaction X 2 Q03338 P20053 affinity chromatography technology 14759368 physical association X 2 Q03338 P20053 affinity chromatography technology 11805826 physical association X 2 Q03338 P20053 two hybrid 11283351 direct interaction X 2 P10591 P20053 affinity chromatography technology 10606269 physical association X 2 P57743 P20053 affinity chromatography technology 10747033 physical association X 2 P57743 P20053 affinity chromatography technology 19740761 physical association X 2 P57743 P20053 affinity chromatography technology 14759368 physical association X 2 Q02260 P20053 affinity chromatography technology 17200106 physical association X 2 Q02554 P20053 affinity chromatography technology 17200106 physical association X 2 P20053 P20095 affinity chromatography technology 16554755 physical association X 2 P20053 P28007 affinity chromatography technology 16554755 physical association X 2 Q12481 P20053 affinity chromatography technology 16554755 physical association X 2 Q12420 P20053 affinity chromatography technology 16429126 physical association X 2 Q12420 P20053 affinity chromatography technology 17200106 physical association X 2 Q12420 P20053 affinity chromatography technology 21614000 physical association X 2 Q12420 P20053 affinity chromatography technology 11805826 physical association X 2 P53905 P20053 two hybrid 10900456 direct interaction X 2 P53905 P20053 affinity chromatography technology 16429126 physical association X 2 P53905 P20053 affinity chromatography technology 17200106 physical association X 2 P53905 P20053 affinity chromatography technology 11805826 physical association X 2 Q04693 P20053 affinity chromatography technology 17200106 physical association X 2 P53276 P20053 affinity chromatography technology 16554755 physical association X 2 Q06406 P20053 affinity chromatography technology 16554755 physical association X 2 Q06406 P20053 affinity chromatography technology 16429126 physical association X 2 Q06406 P20053 affinity chromatography technology 17200106 physical association X 2 P54999 P20053 affinity chromatography technology 16554755 physical association X 2 P54999 P20053 affinity chromatography technology 17200106 physical association X 2 P54999 P20053 affinity chromatography technology 11805826 physical association X 2 P22147 P20053 affinity chromatography technology 17200106 physical association X 2 P19735 P20053 biochemical 8146658 association X 2 P19735 P20053 affinity chromatography technology 16554755 physical association X 2 P19735 P20053 affinity chromatography technology 16429126 physical association X 2 P19735 P20053 affinity chromatography technology 17200106 physical association X 2 P19735 P20053 affinity chromatography technology 11805826 physical association X 2 P19735 P20053 affinity chromatography technology 11805837 physical association X 2 Q06217 P20053 affinity chromatography technology 16554755 physical association X 2 Q06217 P20053 affinity chromatography technology 17200106 physical association X 2 P39990 P20053 affinity chromatography technology 16554755 physical association X 2 P40089 P20053 affinity chromatography technology 16429126 physical association X 2 P39517 P20053 affinity chromatography technology 17200106 physical association X 2 P40089 P20053 affinity chromatography technology 17200106 physical association X 2 P40089 P20053 affinity chromatography technology 11805826 physical association X 2 Q12499 P20053 affinity chromatography technology 16554755 physical association X 2 P38203 P20053 affinity chromatography technology 16554755 physical association X 2 P38203 P20053 affinity chromatography technology 16429126 physical association X 2 P38203 P20053 affinity chromatography technology 17200106 physical association X 2 Q02931 P20053 affinity chromatography technology 16554755 physical association X 2 P39682 P20053 affinity chromatography technology 17200106 physical association X 2 Q12330 P20053 affinity chromatography technology 17200106 physical association X 2 Q12330 P20053 affinity chromatography technology 11805826 physical association X 2 P47083 P20053 affinity chromatography technology 16554755 physical association X 2 Q12460 P20053 affinity chromatography technology 16554755 physical association X 2 P49960 P20053 affinity chromatography technology 17200106 physical association X 2 P43321 P20053 affinity chromatography technology 17200106 physical association X 2 P40018 P20053 affinity chromatography technology 16554755 physical association X 2 P40018 P20053 affinity chromatography technology 16429126 physical association X 2 P40018 P20053 affinity chromatography technology 17200106 physical association X 2 P40018 P20053 affinity chromatography technology 21558325 physical association X 2 P47093 P20053 two hybrid 10900456 direct interaction X 2 P47093 P20053 affinity chromatography technology 10747033 physical association X 2 P47093 P20053 affinity chromatography technology 17200106 physical association X 2 P47017 P20053 affinity chromatography technology 17200106 physical association X 2 Q12159 P20053 affinity chromatography technology 17922018 physical association X 2 P32524 P20053 affinity chromatography technology 16429126 physical association X 2 P32524 P20053 affinity chromatography technology 17200106 physical association X 2 Q08963 P20053 affinity chromatography technology 17200106 physical association X 2 Q08963 P20053 affinity chromatography technology 21558325 physical association X 2 P32639 P20053 affinity chromatography technology 11720284 physical association X 2 P32639 P20053 biochemical 10449419 association X 2 P32639 P20053 biochemical 10377396 association X 2 P32639 P20053 affinity chromatography technology 16554755 physical association X 2 P32639 P20053 affinity chromatography technology 16429126 physical association X 2 P32639 P20053 affinity chromatography technology 16429126 physical association X 2 P32639 P20053 affinity chromatography technology 17200106 physical association X 2 P32639 P20053 affinity chromatography technology 18953335 physical association X 2 P32639 P20053 affinity chromatography technology 14759368 physical association X 2 P38282 P20053 affinity chromatography technology 16429126 physical association X 2 P38282 P20053 affinity chromatography technology 17200106 physical association X 2 P38282 P20053 affinity chromatography technology 11805826 physical association X 2 P20053 P15646 affinity chromatography technology 16554755 physical association X 2 P20053 Q12368 affinity chromatography technology 16429126 physical association X 2 P20053 P32357 affinity chromatography technology 17200106 physical association X 2 P20053 Q07350 affinity chromatography technology 17200106 physical association X 2 P20053 Q12368 affinity chromatography technology 17200106 physical association X 2 P20053 Q12368 affinity chromatography technology 11805826 physical association X 2 P15705 P20053 affinity chromatography technology 11805837 physical association X 2 Q08492 P20053 affinity chromatography technology 16554755 physical association X 2 P36048 P20053 affinity chromatography technology 16429126 physical association X 2 P36048 P20053 affinity chromatography technology 16429126 physical association X 2 P36048 P20053 affinity chromatography technology 17200106 physical association X 2 P36048 P20053 affinity chromatography technology 11805826 physical association X 2 P25644 P20053 affinity chromatography technology 17200106 physical association X 2 P22137 P20053 anti tag coimmunoprecipitation 11805837 physical association X 2 P20053 tandem affinity purification 11805826 - C 10 P20053 inferred by author 11805826 physical association C 82 P20053 anti tag coimmunoprecipitation 11805837 - C 3 P20053 tandem affinity purification 11805826 - C 16 P20053 tandem affinity purification 11805826 - C 7 P20053 tandem affinity purification 11805826 - C 25 P20053 tandem affinity purification 11805826 - C 34 P20053 tandem affinity purification 11805826 - C 16 P20053 inferred by author 11805826 physical association C 46 P20053 cosedimentation through density gradient 18953335 physical association C 17 P20053 tandem affinity purification 18953335 physical association C 17 P20053 electron tomography 18953335 physical association C 17 P19882 P20053 anti tag coimmunoprecipitation 11805837 physical association X 2 P15442 P20053 tandem affinity purification 11805826 physical association X 2 P40204 P20053 tandem affinity purification 11805826 physical association X 2 P06169 P20053 anti tag coimmunoprecipitation 11805837 physical association X 2 P20053 biochemical 10747033 physical association X 2 P20053 two hybrid 10900456 physical association X 2 P49704 P20053 tandem affinity purification 11805826 physical association X 2 P49704 P20053 tandem affinity purification 11805826 physical association X 2 P33334 P20053 tandem affinity purification 11805826 physical association X 2 P32381 P20053 anti tag coimmunoprecipitation 11805837 physical association X 2 P02829 P20053 anti tag coimmunoprecipitation 11805837 physical association X 2 P00924 P20053 anti tag coimmunoprecipitation 11805837 physical association X 2 P14742 P20053 anti tag coimmunoprecipitation 11805837 physical association X 2 P32495 P20053 tandem affinity purification 11805826 physical association X 2 P20053 anti tag coimmunoprecipitation 11805837 physical association X 2 P35191 P20053 anti tag coimmunoprecipitation 11805837 physical association X 2 Q12329 P20053 anti tag coimmunoprecipitation 11805837 physical association X 2 Q03338 P20053 affinity chromatography technology 9826507 physical association X 2 Q03338 P20053 two hybrid pooling approach 11283351 physical association X 2 Q03338 P20053 two hybrid pooling approach 11283351 physical association X 2 Q03338 P20053 tandem affinity purification 11805826 physical association X 2 Q03338 P20053 two hybrid 9826507 physical association X 2 P57743 P20053 biochemical 10747033 physical association X 2 P47135 P20053 two hybrid pooling approach 11283351 physical association X 2 P00830 P20053 anti tag coimmunoprecipitation 11805837 physical association X 2 P20053 inferred by author 11805826 physical association C 51 P20053 tandem affinity purification 11805826 - C 7 P20053 anti tag coimmunoprecipitation 11805837 - C 93 P20053 tandem affinity purification 11805826 - C 22 P20053 tandem affinity purification 11805826 - C 18 P20053 anti tag coimmunoprecipitation 11805837 - C 47 P20053 anti tag coimmunoprecipitation 11805837 - C 17 P20053 tandem affinity purification 11805826 - C 28 P20053 inferred by author 11805826 physical association C 36 P20053 inferred by author 11805826 physical association C 46 P20053 tandem affinity purification 11805826 - C 8 Q12420 P20053 tandem affinity purification 11805826 physical association X 2 P20053 two hybrid 10900456 physical association X 2 P20053 tandem affinity purification 11805826 physical association X 2 P54999 P20053 tandem affinity purification 11805826 physical association X 2 P19735 P20053 tandem affinity purification 11805826 physical association X 2 P19735 P20053 anti tag coimmunoprecipitation 11805837 physical association X 2 P40089 P20053 tandem affinity purification 11805826 physical association X 2 Q12330 P20053 tandem affinity purification 11805826 physical association X 2 P43321 P20053 biochemical 10377396 physical association X 2 P04173 P20053 anti tag coimmunoprecipitation 11805837 physical association X 2 P25694 P20053 anti tag coimmunoprecipitation 11805837 physical association X 2 P05694 P20053 anti tag coimmunoprecipitation 11805837 physical association X 2 P32639 P20053 tandem affinity purification 18953335 physical association X 2 P38282 P20053 tandem affinity purification 11805826 physical association X 2 P53309 P20053 two hybrid pooling approach 11283351 physical association X 2 P20053 P15992 anti tag coimmunoprecipitation 11805837 physical association X 2 P20053 Q12368 tandem affinity purification 11805826 physical association X 2 P15705 P20053 anti tag coimmunoprecipitation 11805837 physical association X 2 P36048 P20053 tandem affinity purification 11805826 physical association X 2 P20053 tandem affinity purification 11805826 association C 8 P20053 tandem affinity purification 11805826 association C 10 P20053 tandem affinity purification 16429126 association C 13 P20053 tandem affinity purification 11805826 association C 8 P20053 tandem affinity purification 11805826 association C 8 P20053 anti tag coimmunoprecipitation 11805837 association C 3 P20053 inferred by author 16429126 physical association C 52 P20053 anti tag coimmunoprecipitation 11805837 association C 3 P20053 tandem affinity purification 23560879 association C 9 P20053 tandem affinity purification 16429126 association C 21 P20053 inferred by author 16429126 physical association C 44 P20053 tandem affinity purification 16429126 association C 20 P20053 tandem affinity purification 16429126 association C 6 P20053 tandem affinity purification 11805826 association C 25 P20053 tandem affinity purification 16429126 association C 21 P20053 tandem affinity purification 16429126 association C 24 P20053 tandem affinity purification 16429126 association C 34 P20053 tandem affinity purification 11805826 association C 16 P20053 tandem affinity purification 11805826 association C 19 P20053 tandem affinity purification 16429126 association C 47 P20053 tandem affinity purification 16429126 association C 31 P20053 tandem affinity purification 16429126 association C 14 P20053 tandem affinity purification 16429126 association C 22 P20053 tandem affinity purification 16429126 association C 44 P20053 tandem affinity purification 16429126 association C 37 P20053 tandem affinity purification 16429126 association C 35 P20053 inferred by author 16429126 physical association C 62 P20053 tandem affinity purification 21179020 association C 80 P20053 tandem affinity purification 16429126 association C 13 P20053 inferred by author 16429126 physical association C 70 P20053 tandem affinity purification 11805826 association C 34 P20053 inferred by author 16429126 physical association C 54 P20053 tandem affinity purification 16429126 association C 35 P49704 P20053 tandem affinity purification 16554755 physical association X 2 P49704 P20053 tandem affinity purification 16554755 physical association X 2 P49704 P20053 tandem affinity purification 16554755 physical association X 2 Q06506 P20053 tandem affinity purification 16554755 physical association X 2 P33399 P20053 tandem affinity purification 16554755 physical association X 2 Q12136 P20053 tandem affinity purification 16554755 physical association X 2 Q01080 P20053 tandem affinity purification 16554755 physical association X 2 Q03338 P20053 two hybrid fragment pooling approach 11283351 physical association X 2 Q03338 P20053 two hybrid fragment pooling approach 11283351 physical association X 2 Q03338 P20053 anti tag coimmunoprecipitation 14759368 physical association X 2 Q03338 P20053 two hybrid 18719252 physical association X 2 P57743 P20053 anti tag coimmunoprecipitation 14759368 physical association X 2 P47135 P20053 two hybrid fragment pooling approach 11283351 physical association X 2 P20053 P20095 tandem affinity purification 16554755 physical association X 2 P20053 P28007 tandem affinity purification 16554755 physical association X 2 P20053 tandem affinity purification 11805826 association C 9 P20053 tandem affinity purification 16429126 association C 27 P20053 tandem affinity purification 11805826 association C 23 P20053 tandem affinity purification 16429126 association C 20 P20053 tandem affinity purification 16429126 association C 12 P20053 inferred by author 16429126 physical association C 38 P20053 inferred by author 16429126 physical association C 26 P20053 tandem affinity purification 16429126 association C 10 P20053 tandem affinity purification 11805826 association C 16 P20053 inferred by author 16429126 physical association C 36 P20053 tandem affinity purification 11805826 association C 28 P20053 tandem affinity purification 16429126 association C 15 P20053 inferred by author 16554755 association C 5 P20053 tandem affinity purification 16429126 association C 52 P20053 tandem affinity purification 16429126 association C 18 P20053 tandem affinity purification 16429126 association C 25 Q12481 P20053 tandem affinity purification 16554755 physical association X 2 P53905 P20053 two hybrid 10900456 physical association X 2 P53276 P20053 tandem affinity purification 16554755 physical association X 2 Q06406 P20053 tandem affinity purification 16554755 physical association X 2 P54999 P20053 tandem affinity purification 16554755 physical association X 2 P54999 P20053 tandem affinity purification 16554755 physical association X 2 P19735 P20053 tandem affinity purification 16554755 physical association X 2 Q06217 P20053 tandem affinity purification 16554755 physical association X 2 P39990 P20053 tandem affinity purification 16554755 physical association X 2 Q12499 P20053 tandem affinity purification 16554755 physical association X 2 P38203 P20053 tandem affinity purification 16554755 physical association X 2 P38203 P20053 tandem affinity purification 16554755 physical association X 2 Q02931 P20053 tandem affinity purification 16554755 physical association X 2 P47083 P20053 tandem affinity purification 16554755 physical association X 2 Q12460 P20053 tandem affinity purification 16554755 physical association X 2 P40018 P20053 tandem affinity purification 16554755 physical association X 2 P47093 P20053 two hybrid 10900456 physical association X 2 P32639 P20053 anti tag coimmunoprecipitation 14759368 physical association X 2 P32639 P20053 tandem affinity purification 16554755 physical association X 2 P53309 P20053 two hybrid fragment pooling approach 11283351 physical association X 2 P20053 P15646 tandem affinity purification 16554755 physical association X 2 Q08492 P20053 tandem affinity purification 16554755 physical association X 2 P20053 confirmational text mining - - C 33 P20053 mass spectrometry studies of complexes 11805826 - C 92 P20053 mass spectrometry studies of complexes 11805826 - C 92 Q03338 P20053 two hybrid 11283351 - X 2 Q03338 P20053 interaction detection method 9826507 - X 2 Q03338 P20053 interaction detection method - - X 2 Q03338 P20053 two hybrid 11283351 - X 2 Q03338 P20053 two hybrid 9826507 - X 2 P47135 P20053 two hybrid 11283351 - X 2 P20053 mass spectrometry studies of complexes 11805826 - C 48 P20053 mass spectrometry studies of complexes 11805826 - C 51 P20053 mass spectrometry studies of complexes 11805837 - C 48 P20053 mass spectrometry studies of complexes 11805826 - C 40 P20053 mass spectrometry studies of complexes 11805837 - C 4 P20053 mass spectrometry studies of complexes 11805837 - C 4 P20053 mass spectrometry studies of complexes 11805826 - C 58 Q12420 P20053 affinity chromatography technology 10449419 - X 2 P53905 P20053 two hybrid 10900456 - X 2 P47093 P20053 two hybrid 10900456 - X 2 P32524 P20053 interaction detection method 8405998 - X 2 Q00816 P20053 interaction detection method 8005438 - X 2 P53309 P20053 two hybrid 11283351 - X 2

PPI - HINT Gene A Gene B PMID Method Quality PRP6 PRP4 8146658 0401 LC PRP4 PRP19 11804584 0401 LC PRP4 BRR2 10377396,10449419 0401,0401 LC PRP4 SMD3 10377396 0401 LC PRP4 LSM8 10747033,10747033,10900456 0401,0004,0018 LC,HT PRP4 JSN1 11283351,11283351,11283351 0018,0399,0398 HT PRP4 YAP1802 11283351,11283351,11283351 0018,0399,0398 HT PRP4 LSM7 10900456 0018 HT PRP4 LSM3 10747033,10747033 0401,0004 LC PRP4 PRP3 11804584,9826507,11283351,11283351,9826507,9826507,10449419,9826507,18719252,11283351,9826507 0045,0019,0399,0398,0018,0004,0045,0045,0018,0018,0096 LC,HT ATP2 PRP4 11805837 0007 HT ENO1 PRP4 11805837 0007 HT HSP82 PRP4 11805837 0007 HT LEU2 PRP4 11805837 0007 HT HTA2 PRP4 21179020 0676 HT MET6 PRP4 11805837 0007 HT PDC1 PRP4 11805837 0007 HT SSA1 PRP4 10606269,16429126 0004,0676 LC,HT SSB1 PRP4 16429126 0676 HT GFA1 PRP4 11805837 0007 HT GCN2 PRP4 11805826,16429126,11805826,16429126,11805826 0004,0004,0007,0676,0676 HT NOP1 PRP4 16554755,16554755 0676,0004 HT STI1 PRP4 11805837,11805837 0004,0007 HT HSP26 PRP4 11805837 0007 HT PRP6 PRP4 11805837,16554755,16429126,11805826,11805837,11805826,16554755,17200106,11805826,16429126,8146658 0004,0676,0676,0676,0007,0004,0004,0004,0007,0004,0401 HT,LC PRP9 PRP4 17200106 0004 HT HSP60 PRP4 11805837 0007 HT PRP4 PRP4 11805826,11805826 0676,0007 HT PRP4 PRP2 16554755,16554755 0676,0004 HT PRP4 CHC1 11805837 0007 HT PRP4 XRN1 17200106 0004 HT PRP4 SCJ1 11805837 0007 HT PRP4 MSH3 16429126 0676 HT PRP4 PAT1 17200106 0004 HT PRP4 CDC48 11805837 0007 HT PRP4 GAR1 16554755,16554755 0676,0004 HT PRP4 CRM1 26673895,26673895 0096,0004 LC PRP4 AAR2 17200106,16429126 0004,0363 HT PRP4 ARP2 11805837,11805837 0004,0007 HT PRP4 NHP2 11805826,16429126,11805826,11805826 0004,0676,0007,0676 HT PRP4 PRP19 11842115,11804584 0004,0401 LC PRP4 PRP21 17200106,16429126,16429126 0004,0676,0004 HT PRP4 BRR2 11720284,18953335,14759368,16554755,16429126,25670679,17200106,18953335,10377396,10449419,14759368,16429126,16554755 0004,0676,0007,0676,0676,0004,0004,0004,0401,0401,0004,0004,0004 LC,HT PRP4 PRP8 16373487,16429126,11805826,11805826,17200106,11805826,16429126 0004,0004,0676,0004,0004,0007,0676 LC,HT PRP4 LHP1 16554755,16554755 0676,0004 HT PRP4 MDJ1 11805837 0007 HT PRP4 SNU114 16429126,11805826,11805826,17200106,11805826,16429126 0676,0676,0004,0004,0007,0004 HT PRP4 LSM2 16429126,17200106,16429126,16554755,16554755 0004,0004,0676,0676,0004 HT PRP4 SPP381 16429126,11805826,11805826,17200106,11805826,16429126 0676,0676,0004,0004,0007,0004 HT PRP4 DHH1 17200106 0004 HT PRP4 PRP39 17200106 0004 HT PRP4 SNU13 16554755,16554755 0676,0004 HT PRP4 SMB1 16554755,16429126,21558325,17200106,16429126,16554755 0004,0676,0004,0004,0004,0676 HT,LC PRP4 LSM4 17200106,16429126,16429126 0004,0676,0004 HT PRP4 LSM5 16429126,11805826,11805826,17200106,11805826,16429126 0676,0676,0004,0004,0007,0004 HT PRP4 SMX2 11805826,16429126,11805826,11805826 0004,0676,0007,0676 HT PRP4 SMD3 17200106,10377396 0004,0401 HT,LC PRP4 RPS0B 16429126 0676 HT PRP4 LSM1 17200106 0004 HT PRP4 MPP10 16554755,16554755 0676,0004 HT PRP4 LSM8 23560879,16429126,23560879,10747033,10747033,17200106 0676,0676,0004,0401,0004,0004 LC,HT PRP4 PRP31 16554755,16429126,11805826,11805826,17200106,11805826,16429126,16554755 0004,0676,0676,0004,0004,0007,0004,0676 HT PRP4 HSH155 17200106 0004 HT PRP4 PRP24 17200106 0004 HT PRP4 SNU71 17200106 0004 HT PRP4 UTP8 16554755,16554755 0676,0004 HT PRP4 FOL1 16429126 0676 HT PRP4 LSM7 16429126,11805826,11805826,17200106,11805826,16429126 0676,0004,0676,0004,0007,0004 HT PRP4 SMX3 16554755,16429126,11805826,11805826,17200106,11805826,16554755 0676,0676,0676,0004,0004,0007,0004 HT PRP4 LSM3 14759368,16429126,19740761,10747033,10747033,14759368 0007,0676,0004,0401,0004,0004 HT,LC PRP4 PRP38 17200106 0004 HT PRP4 RPA49 16554755,16554755 0676,0004 HT PRP4 SMD1 17200106 0004 HT PRP4 CUS1 17200106 0004 HT PRP4 NAN1 16554755,16554755 0676,0004 HT PRP4 PRP3 14759368,17200106,9826507,9826507,9826507,16429126,11805826,14759368,9826507,16429126,11805826,9826507,11805826 0007,0004,0019,0018,0004,0676,0004,0004,0045,0004,0676,0096,0007 HT,LC PRP4 RSE1 17200106 0004 HT PRP4 SMD2 17200106,16554755,16554755 0004,0676,0004 HT PRP4 LSM6 16554755,16429126,17200106,16429126,16554755 0004,0676,0004,0004,0676 HT PRP4 RRP9 16554755,16554755 0676,0004 HT PRP4 DIB1 17200106 0004 HT PRP4 PRP11 17200106 0004 HT PRP4 BUD21 16554755,16554755,16554755 0363,0676,0004 HT PRP4 CBC2 24500206 0004 LC PRP4 LEA1 21558325,17200106 0004,0004 LC,HT PRP4 SAS10 16554755,16554755 0676,0004 HT PRP4 YRA1 17922018 0004 LC PRP4 HSP42 11805837 0007 HT PRP4 SME1 11805826,16429126,11805826,11805826,17200106 0004,0676,0007,0676,0004 HT PRP4 SNU23 16429126,11805826,11805826,17200106,11805826,16429126 0676,0676,0004,0004,0007,0004 HT PRP4 SNU66 10449419,16429126,11805826,11805826,17200106,11805826,21614000,16429126 0004,0676,0004,0676,0004,0007,0004,0004 LC,HT PRP4 NOP56 16554755,16554755 0676,0004 HT PRP4 RRP36 16554755,16554755 0676,0004 HT PRP4 NOP58 16554755,16554755 0676,0004 HT

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID P20053 P15705 PRP4 STI1 0.332 11805837 P53309 P20053 YAP1802 PRP4 0.21 11283351 Q12159 P20053 YRA1 PRP4 0.126 17922018 P20053 P15992 PRP4 HSP26 0.126 11805837 Q12330 P20053 SME1 PRP4 0.286 11805826,16429126 Q12460 P20053 NOP56 PRP4 0.126 16554755 Q8N6Y0 P20053 USHBP1 PRP4 0.332 27107014 P25336 P20053 MSH3 PRP4 0.126 16429126 P20053 P02829 PRP4 HSP82 0.126 11805837 P20053 P04173 PRP4 LEU2 0.126 11805837 P20053 P04912 PRP4 HTA2 0.126 21179020 P20053 P05694 PRP4 MET6 0.126 11805837 P20053 P19735 PRP4 PRP6 0.623 11805826,16429126,16554755,11805837 P20053 P10591 PRP4 SSA1 0.309 16429126,10606269 P47093 P20053 LSM8 PRP4 0.702 23560879,16429126,10747033,10900456 P30822 P20053 CRM1 PRP4 0.236 26673895 P20053 O43186 PRP4 CRX 0.332 27107014 P20053 A0A024R0Y4 PRP4 TADA2L {ECO:0000313|EMBL:EAW57589.1} 0.332 27107014 Q06406 P20053 LSM6 PRP4 0.332 16554755,16429126 Q03338 P20053 PRP3 PRP4 0.787 11805826,16429126,9826507,14759368,18719252,11283351 Q8N684 P20053 CPSF7 PRP4 0.416 27107014 P40018 P20053 SMB1 PRP4 0.416 16554755,21558325,16429126 P35191 P20053 MDJ1 PRP4 0.126 11805837 P28007 P20053 GAR1 PRP4 0.126 16554755 P38203 P20053 LSM2 PRP4 0.236 16554755,16429126 P38282 P20053 SPP381 PRP4 0.416 11805826,16429126 P32357 P20053 AAR2 PRP4 0.126 16429126 P32381 P20053 ARP2 PRP4 0.236 11805837 P32524 P20053 PRP21 PRP4 0.126 16429126 P32639 P20053 BRR2 PRP4 0.74 16429126,18953335,14759368,10449419,16554755,25670679 P33399 P20053 LHP1 PRP4 0.126 16554755 P39990 P20053 SNU13 PRP4 0.126 16554755 Q9UJV3 P20053 MID2 PRP4 0.332 27107014 P40070 P20053 LSM4 PRP4 0.126 16429126 P36048 P20053 SNU114 PRP4 0.376 11805826,16429126 P47083 P20053 MPP10 PRP4 0.126 16554755 P47135 P20053 JSN1 PRP4 0.236 11283351 P49704 P20053 PRP31 PRP4 0.597 16554755,11805826,16429126 Q01080 P20053 RPA49 PRP4 0.126 16554755 P20053 P19882 PRP4 HSP60 0.126 11805837 P43321 P20053 SMD3 PRP4 0.033 10377396 P20053 P00830 PRP4 ATP2 0.126 11805837 P20053 P00924 PRP4 ENO1 0.126 11805837 P20053 P02407 PRP4 RPS17A 0.21 27244240 P20053 P06169 PRP4 PDC1 0.126 11805837 P20053 P11484 PRP4 SSB1 0.126 16429126 P20053 P14373 PRP4 TRIM27 0.332 27107014 P20053 P14742 PRP4 GFA1 0.126 11805837 P20053 P15442 PRP4 GCN2 0.332 11805826,16429126 P20053 P20053 PRP4 PRP4 0.155 11805826 P20095 P20053 PRP2 PRP4 0.236 16554755 P22137 P20053 CHC1 PRP4 0.126 11805837 P25303 P20053 SCJ1 PRP4 0.126 11805837 P25694 P20053 CDC48 PRP4 0.126 11805837 P32495 P20053 NHP2 PRP4 0.332 11805826,16429126 P33334 P20053 PRP8 PRP4 0.396 11805826,16429126 P40089 P20053 LSM5 PRP4 0.416 11805826,16429126 P40204 P20053 SMX2 PRP4 0.332 11805826,16429126 P46654 P20053 RPS0B PRP4 0.126 16429126 P53276 P20053 UTP8 PRP4 0.126 16554755 P53905 P20053 LSM7 PRP4 0.597 11805826,16429126,10900456 P54999 P20053 SMX3 PRP4 0.416 16554755,11805826,16429126 P57743 P20053 LSM3 PRP4 0.436 19740761,16429126,10747033,14759368 Q02931 P20053 NAN1 PRP4 0.126 16554755 Q06217 P20053 SMD2 PRP4 0.236 16554755 Q06506 P20053 RRP9 PRP4 0.126 16554755 Q08492 P20053 BUD21 PRP4 0.236 16554755 Q12136 P20053 SAS10 PRP4 0.126 16554755 Q12329 P20053 HSP42 PRP4 0.126 11805837 Q12368 P20053 SNU23 PRP4 0.286 11805826,16429126 Q12420 P20053 SNU66 PRP4 0.376 11805826,21614000,16429126 Q12481 P20053 RRP36 PRP4 0.126 16554755 Q12499 P20053 NOP58 PRP4 0.126 16554755 Q8NHQ1 P20053 CEP70 PRP4 0.332 27107014 P53848 P20053 FOL1 PRP4 0.126 16429126 P53849 P20053 GIS2 PRP4 0.126 21232131 P20053 P15646 PRP4 NOP1 0.126 16554755 Q08963 P20053 LEA1 PRP4 0.126 21558325