iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

mRNA Expression
GEO	FFGED
Protein-protein Interaction
IID	iRefIndex	HINT	Mentha
Post-translational Modifications (PTMs)
dbPAF	UniProt	PHOSIDA	BioGRID
Protein Expression/Proteomics
GPMDB

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E3 adaptor/Cullin RING/APC_C/APC_C	APC_C	21107322; 16763193

Reviewed

Classification

Family	Identity	E-value	Score	Source Orthology
E3 adaptor/Cullin RING/SCF/F-box	30.77	4.40e-01	32.70	IUUC-Ath-006894

Organism

Saccharomyces cerevisiae

Functional Description
(View)

The APC/C is composed of at least 13 subunits that stay tightly associated throughout the cell cycle: APC1, APC2, APC4, APC5, APC9, APC11, CDC16, CDC23, CDC26, CDC27, DOC1, MND2 and SWM1. MND2 interacts directly with APC1, APC5 and CDC23.

Protein Sequence
(Fasta)

MARALRDISL FNDIRKDQNS AGAKHERYNM RDLRSKKNQH VNGIDDYEDD SLDRFIRRKK 60
SRVVKYIPSL SAYNVFNEFP YYPTSASQLL DGKLDEFLML SEQYKSRLPK IRKLGWNRFK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCAAGAG CGTTGAGGGA TATATCATTA TTCAATGATA TAAGAAAGGA TCAAAATTCG 60
GCAGGAGCCA AGCATGAGAG ATATAACATG AGAGATCTCC GAAGTAAGAA GAACCAGCAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0131--Cell cycle
KW-0132--Cell division
KW-0181--Complete proteome
KW-0498--Mitosis
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR008402--APC_su15/mnd2
IPR016807--Mnd2

Pfam

PF05841--Apc15p

Gene Ontology

GO:0005680--C:anaphase-promoting complex
GO:0005634--C:nucleus
GO:0031145--P:anaphase-promoting complex-dependent catabolic process
GO:0051301--P:cell division
GO:0000070--P:mitotic sister chromatid segregation
GO:0051865--P:protein autoubiquitination
GO:0016567--P:protein ubiquitination
GO:0007131--P:reciprocal meiotic recombination
GO:0030071--P:regulation of mitotic metaphase/anaphase transition

KEGG

sce:YIR025W

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000768	Aegilops tauschii	27.27	1.60e-02	31.20
IUUC-Aly-006080	Arabidopsis lyrata	29.23	1.10e-02	32.30
IUUC-Ath-006894	Arabidopsis thaliana	30.77	6.00e-03	33.10
IUUC-Ago-007964	Ashbya gossypii	33.33	2.00e-04	37.00
IUUC-Ate-010273	Aspergillus terreus	33.33	1.20e-02	31.60
IUUC-Cgl-026731	Colletotrichum gloeosporioides	28.28	4.10e-02	30.80
IUUC-Dor-030942	Dipodomys ordii	34.62	3.10e-01	30.00
IUUC-Dse-031389	Dothistroma septosporum	42.31	9.00e-03	32.70
IUUC-Eca-033881	Equus caballus	32.65	4.50e-02	30.00
IUUC-Fca-035450	Felis catus	43.75	2.50e-01	28.90
IUUC-Fox-038072	Fusarium oxysporum	40.00	1.30e-02	32.70
IUUC-Kpa-049167	Komagataella pastoris	32.08	5.30e-02	29.30
IUUC-Lch-050234	Latimeria chalumnae	52.17	2.60e-02	29.60
IUUC-Mor-057206	Magnaporthe oryzae	34.04	6.00e-03	31.20
IUUC-Mtr-058318	Medicago truncatula	42.42	1.30e-02	30.80
IUUC-Mla-058811	Melampsora laricipopulina	26.67	1.30e-01	29.30
IUUC-Nfi-068369	Neosartorya fischeri	26.09	6.30e-02	29.30
IUUC-Ont-072295	Oreochromis niloticus	48.48	1.10e-01	29.60
IUUC-Ocu-074468	Oryctolagus cuniculus	34.62	7.20e-02	32.30
IUUC-Opu-083992	Oryza punctata	32.43	5.70e-01	26.20
IUUC-Ptr-091215	Pan troglodytes	36.59	2.30e-02	27.70
IUUC-Psi-093634	Pelodiscus sinensis	32.81	3.30e-02	29.60
IUUC-Ppa-095762	Physcomitrella patens	36.92	2.70e-02	31.60
IUUC-Pop-100056	Populus trichocarpa	48.15	9.00e-03	32.30
IUUC-Pyt-104591	Pyrenophora triticirepentis	35.48	7.40e-02	29.60
IUUC-Sit-110137	Setaria italica	30.53	1.30e-01	30.00
IUUC-Sly-111820	Solanum lycopersicum	34.38	6.90e-01	26.60
IUUC-Ssc-115659	Sus scrofa	33.33	1.70e-02	32.30
IUUC-Tur-126313	Triticum urartu	30.43	2.70e-01	28.90
IUUC-Uma-129646	Ustilago maydis	25.71	2.40e-01	27.70
IUUC-Yli-134493	Yarrowia lipolytica	24.44	1.90e-01	29.30

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence