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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Cel-018247
UUCD1 version UUC-CaE-00712
Ensembl Protein ID K07D4.3
UniProt Accession O76577; PSDE_CAEEL
Genbank Protein ID CCD72745.1
Protein Name 26S proteasome non-ATPase regulatory subunit 14; 26S proteasome regulatory subunit rpn11
Genbank Nucleotide ID FO081599
Gene Name rpn-11; K07D4.3
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
WBGene00004467 K07D4.3 K07D4.3
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
microRNAmiRNAMapRAID2
Protein-protein Interaction
IIDiRefIndexPINAMentha
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/JAMM 1.20e-07 31.9 115 128
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/JAMM
   S: 1    HSHPgftcwlSsVD 14
           HSHPgf+cwlS+VD
   Q: 115  HSHPGFGCWLSGVD 128
           *************9 PP
   
Organism Caenorhabditis elegans
Functional Description
(View)

Functional Description


     Metalloprotease component of the 26S proteasome that specifically cleaves 'Lys-63'-linked polyubiquitin chains. The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The function of the 'Lys-63'-specific deubiquitination of the proteasome is unclear (By similarity).
 Metalloprotease component of the 26S proteasome that specifically cleaves 'Lys-63'-linked polyubiquitin chains. The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The function of the 'Lys-63'-specific deubiquitination of the proteasome is unclear (By similarity).
Protein Sequence
(Fasta)
MERFLRLGGL GGNLGTFGAN PQDSNQVDTS ETVYISSLAL LKMLKHGRAG VPMEVMGLML 60
GEFVDDYTVN VIDVFAMPQS GTGVSVEAVD PVFQAKMLDM LKQTGRPEMV VGWYHSHPGF 120
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Protein Fasta Sequence


>IUUC-Cel-018247|DUB,JAMM|Caenorhabditis elegans
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Nucleotide Sequence
(Fasta)
AGAGGAATGG AGCGATTCCT GCGACTCGGA GGTCTTGGTG GAAACCTTGG AACGGTAATT 60
GCATTCTGTT TCGATAGAAA ATCATCTAAA ATTTCGAATA TTTCCAGTTC GGAGCCAATC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Cel-018247|DUB,JAMM|Caenorhabditis elegans
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0482--Metalloprotease
KW-0645--Protease
KW-0647--Proteasome
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
Interpro

IPR000555--JAMM/MPN+_dom
IPR024969--Rpn11/EIF3F_C
Pfam

PF01398--JAB
PF13012--MitMem_reg
SMART

SM00232--JAB_MPN
Gene Ontology

GO:0005838--C:proteasome regulatory particle
GO:0046872--F:metal ion binding
GO:0008237--F:metallopeptidase activity
KEGG cel:CELE_K07D4.3
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000544 Aegilops tauschii 72.03 6.00e-117 412.00
IUUC-Aml-001416 Ailuropoda melanoleuca 76.90 3.00e-133 466.00
IUUC-Atr-002629 Amborella trichopoda 72.30 6.00e-115 405.00
IUUC-Apl-004046 Anas platyrhynchos 76.71 3.00e-133 466.00
IUUC-Aca-005228 Anolis carolinensis 76.90 8.00e-133 464.00
IUUC-Aly-005457 Arabidopsis lyrata 71.72 7.00e-118 415.00
IUUC-Ath-007290 Arabidopsis thaliana 71.72 4.00e-118 416.00
IUUC-Ago-007866 Ashbya gossypii 64.21 3.00e-105 373.00
IUUC-Acl-008338 Aspergillus clavatus 68.42 4.00e-104 369.00
IUUC-Afl-008431 Aspergillus flavus 69.82 1.00e-118 417.00
IUUC-Afu-008909 Aspergillus fumigatus 69.82 1.00e-114 404.00
IUUC-Ani-009174 Aspergillus nidulans 69.45 1.00e-115 407.00
IUUC-Ang-009854 Aspergillus niger 70.55 4.00e-119 419.00
IUUC-Aor-009942 Aspergillus oryzae 69.82 3.00e-118 417.00
IUUC-Ate-010377 Aspergillus terreus 69.45 7.00e-118 415.00
IUUC-Ame-011628 Astyanax mexicanus 81.32 6.00e-124 435.00
IUUC-Bgr-012263 Blumeria graminis 67.03 2.00e-103 367.00
IUUC-Bta-012375 Bos taurus 76.90 3.00e-133 466.00
IUUC-Bci-013850 Botrytis cinerea 71.79 2.00e-110 390.00
IUUC-Bdi-014135 Brachypodium distachyon 72.66 6.00e-115 405.00
IUUC-Bol-016172 Brassica oleracea 71.72 4.00e-118 416.00
IUUC-Bra-017926 Brassica rapa 71.72 4.00e-118 416.00
IUUC-Cja-019210 Callithrix jacchus 76.71 9.00e-134 468.00
IUUC-Cfa-020926 Canis familiaris 76.31 5.00e-129 452.00
IUUC-Cpo-021572 Cavia porcellus 76.90 3.00e-133 466.00
IUUC-Cre-022925 Chlamydomonas reinhardtii 70.14 1.00e-116 410.00
IUUC-Csa-023496 Chlorocebus sabaeus 76.90 3.00e-133 466.00
IUUC-Cho-024525 Choloepus hoffmanni 72.26 8.00e-124 434.00
IUUC-Cin-025492 Ciona intestinalis 76.90 7.00e-134 468.00
IUUC-Cgl-026493 Colletotrichum gloeosporioides 68.13 1.00e-99 354.00
IUUC-Cne-026785 Cryptococcus neoformans 65.84 3.00e-115 406.00
IUUC-Cme-027105 Cyanidioschyzon merolae 62.99 1.00e-103 368.00
IUUC-Dre-028788 Danio rerio 77.78 2.00e-133 466.00
IUUC-Dno-029058 Dasypus novemcinctus 76.71 1.00e-133 468.00
IUUC-Dor-031015 Dipodomys ordii 68.49 5.00e-114 402.00
IUUC-Dse-031242 Dothistroma septosporum 70.50 1.00e-121 427.00
IUUC-Dme-031668 Drosophila melanogaster 77.24 3.00e-134 469.00
IUUC-Ete-033146 Echinops telfairi 71.81 2.00e-107 380.00
IUUC-Eca-033734 Equus caballus 76.90 3.00e-133 466.00
IUUC-Eeu-035168 Erinaceus europaeus 93.33 9.00e-82 295.00
IUUC-Fca-036426 Felis catus 76.90 3.00e-133 466.00
IUUC-Fal-036954 Ficedula albicollis 76.90 8.00e-133 464.00
IUUC-Fox-037838 Fusarium oxysporum 69.68 7.00e-118 415.00
IUUC-Fso-038374 Fusarium solani 69.31 1.00e-117 414.00
IUUC-Gmo-038918 Gadus morhua 77.24 5.00e-133 465.00
IUUC-Ggr-039954 Gaeumannomyces graminis 70.40 7.00e-120 422.00
IUUC-Gga-040377 Gallus gallus 76.90 8.00e-133 464.00
IUUC-Gac-042386 Gasterosteus aculeatus 77.05 1.00e-133 468.00
IUUC-Gma-043789 Glycine max 71.88 6.00e-118 415.00
IUUC-Ggo-044916 Gorilla gorilla 76.71 7.00e-134 468.00
IUUC-Hsa-045865 Homo sapiens 76.90 3.00e-133 466.00
IUUC-Hvu-047188 Hordeum vulgare 72.03 2.00e-117 414.00
IUUC-Itr-048154 Ictidomys tridecemlineatus 89.66 3.00e-91 325.00
IUUC-Kpa-049128 Komagataella pastoris 69.47 2.00e-109 387.00
IUUC-Lch-050167 Latimeria chalumnae 70.75 2.00e-120 423.00
IUUC-Lpe-050688 Leersia perrieri 71.53 4.00e-117 412.00
IUUC-Loc-052888 Lepisosteus oculatus 77.24 2.00e-133 466.00
IUUC-Lma-052962 Leptosphaeria maculans 70.50 2.00e-120 424.00
IUUC-Laf-053949 Loxodonta africana 76.90 3.00e-133 466.00
IUUC-Mcc-055279 Macaca mulatta 78.85 2.00e-131 460.00
IUUC-Meu-055956 Macropus eugenii 69.86 2.00e-117 414.00
IUUC-Mor-057166 Magnaporthe oryzae 70.33 6.00e-110 389.00
IUUC-Mpo-057344 Magnaporthe poae 70.40 4.00e-120 422.00
IUUC-Mtr-057857 Medicago truncatula 72.22 9.00e-119 418.00
IUUC-Mla-058938 Melampsora laricipopulina 67.49 8.00e-117 411.00
IUUC-Mga-060093 Meleagris gallopavo 76.90 8.00e-133 464.00
IUUC-Mvi-060565 Microbotryum violaceum 69.96 3.00e-121 426.00
IUUC-Mmr-060899 Microcebus murinus 77.00 1.00e-131 460.00
IUUC-Mdo-062175 Monodelphis domestica 76.90 7.00e-133 465.00
IUUC-Mmu-063416 Mus musculus 76.90 3.00e-133 466.00
IUUC-Mac-065642 Musa acuminata 70.83 3.00e-116 410.00
IUUC-Mpu-065946 Mustela putorius furo 76.90 3.00e-133 466.00
IUUC-Mlu-067835 Myotis lucifugus 76.71 1.00e-133 467.00
IUUC-Nfi-068279 Neosartorya fischeri 69.82 1.00e-114 404.00
IUUC-Ncr-068821 Neurospora crassa 70.40 2.00e-110 390.00
IUUC-Nle-069212 Nomascus leucogenys 76.90 3.00e-133 466.00
IUUC-Opr-070928 Ochotona princeps 52.30 1.00e-62 231.00
IUUC-Ont-072135 Oreochromis niloticus 77.24 2.00e-133 466.00
IUUC-Oan-072755 Ornithorhynchus anatinus 76.90 7.00e-133 465.00
IUUC-Ocu-074433 Oryctolagus cuniculus 80.45 1.00e-127 447.00
IUUC-Oba-075351 Oryza barthii 72.30 2.00e-114 403.00
IUUC-Obr-076248 Oryza brachyantha 71.53 2.00e-117 414.00
IUUC-Ogl-077831 Oryza glaberrima 72.30 2.00e-114 403.00
IUUC-Ogu-078028 Oryza glumaepatula 72.30 2.00e-114 403.00
IUUC-Oin-080184 Oryza indica 71.53 3.00e-117 412.00
IUUC-Olo-080580 Oryza longistaminata 72.30 3.00e-114 403.00
IUUC-Ome-081739 Oryza meridionalis 70.03 5.00e-112 395.00
IUUC-Oni-082861 Oryza nivara 72.30 2.00e-114 403.00
IUUC-Opu-083352 Oryza punctata 72.30 2.00e-114 403.00
IUUC-Oru-084210 Oryza rufipogon 72.30 2.00e-114 403.00
IUUC-Osa-086114 Oryza sativa 72.30 2.00e-114 403.00
IUUC-Ola-087317 Oryzias latipes 77.24 2.00e-133 466.00
IUUC-Olu-087889 Ostreococcus lucimarinus 70.24 1.00e-122 431.00
IUUC-Oga-088032 Otolemur garnettii 76.71 5.00e-134 469.00
IUUC-Oar-090237 Ovis aries 76.71 6.00e-134 468.00
IUUC-Ptr-090881 Pan troglodytes 76.90 3.00e-133 466.00
IUUC-Pan-092658 Papio anubis 76.71 1.00e-133 468.00
IUUC-Psi-093672 Pelodiscus sinensis 76.90 7.00e-133 465.00
IUUC-Pma-094213 Petromyzon marinus 76.71 5.00e-133 465.00
IUUC-Pno-095038 Phaeosphaeria nodorum 70.14 3.00e-119 420.00
IUUC-Ppa-095467 Physcomitrella patens 73.78 2.00e-120 424.00
IUUC-Pfo-096322 Poecilia formosa 77.24 2.00e-133 466.00
IUUC-Pab-098484 Pongo abelii 76.90 3.00e-133 466.00
IUUC-Pop-099564 Populus trichocarpa 71.88 6.00e-118 415.00
IUUC-Pca-100785 Procavia capensis 74.90 3.00e-112 396.00
IUUC-Ppe-101727 Prunus persica 71.53 5.00e-117 412.00
IUUC-Pva-102569 Pteropus vampyrus 76.71 1.00e-133 468.00
IUUC-Pgr-103351 Puccinia graminis 67.84 2.00e-117 413.00
IUUC-Ptt-103763 Puccinia triticina 65.72 7.00e-108 382.00
IUUC-Pte-104088 Pyrenophora teres 70.00 4.00e-119 419.00
IUUC-Pyt-104597 Pyrenophora triticirepentis 69.26 2.00e-109 387.00
IUUC-Rno-105115 Rattus norvegicus 76.90 3.00e-133 466.00
IUUC-Sce-106353 Saccharomyces cerevisiae 64.48 3.00e-106 376.00
IUUC-Sha-107476 Sarcophilus harrisii 76.90 7.00e-133 465.00
IUUC-Sja-107807 Schizosaccharomyces japonicus 66.90 4.00e-115 406.00
IUUC-Spo-108255 Schizosaccharomyces pombe 65.74 8.00e-106 375.00
IUUC-Ssl-108392 Sclerotinia sclerotiorum 71.12 5.00e-111 392.00
IUUC-Smo-109081 Selaginella moellendorffii 73.08 2.00e-125 440.00
IUUC-Sit-110287 Setaria italica 71.53 4.00e-117 412.00
IUUC-Sly-111656 Solanum lycopersicum 71.88 5.00e-118 416.00
IUUC-Stu-112827 Solanum tuberosum 71.53 1.00e-117 414.00
IUUC-Sar-112979 Sorex araneus 67.47 2.00e-111 393.00
IUUC-Sbi-113841 Sorghum bicolor 71.53 4.00e-117 412.00
IUUC-Sre-114930 Sporisorium reilianum 70.11 8.00e-121 425.00
IUUC-Ssc-116058 Sus scrofa 76.71 7.00e-134 468.00
IUUC-Tgu-116499 Taeniopygia guttata 76.90 8.00e-133 464.00
IUUC-Tru-117576 Takifugu rubripes 77.24 2.00e-133 466.00
IUUC-Tsy-119371 Tarsius syrichta 68.49 1.00e-114 404.00
IUUC-Tni-120868 Tetraodon nigroviridis 76.90 4.00e-131 459.00
IUUC-Tca-121292 Theobroma cacao 71.88 9.00e-118 415.00
IUUC-Tre-122183 Trichoderma reesei 69.68 2.00e-115 407.00
IUUC-Tvi-122566 Trichoderma virens 69.68 3.00e-115 406.00
IUUC-Tae-125543 Triticum aestivum 73.26 8.00e-114 401.00
IUUC-Tur-126034 Triticum urartu 72.66 2.00e-115 406.00
IUUC-Tme-126903 Tuber melanosporum 68.66 8.00e-119 418.00
IUUC-Tbe-127525 Tupaia belangeri 68.15 2.00e-107 380.00
IUUC-Ttr-129072 Tursiops truncatus 76.71 7.00e-134 468.00
IUUC-Uma-129471 Ustilago maydis 70.46 2.00e-121 427.00
IUUC-Vda-129956 Verticillium dahliae 71.06 2.00e-109 387.00
IUUC-Vpa-130490 Vicugna pacos 76.71 7.00e-134 468.00
IUUC-Vvi-131302 Vitis vinifera 71.88 6.00e-118 415.00
IUUC-Xtr-132059 Xenopus tropicalis 77.24 2.00e-133 466.00
IUUC-Xma-133101 Xiphophorus maculatus 77.24 2.00e-133 466.00
IUUC-Yli-134638 Yarrowia lipolytica 67.84 2.00e-113 400.00
IUUC-Zma-135910 Zea mays 71.53 4.00e-117 412.00
Created Date 25-Jun-2017

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