iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID	PINA
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.00e-12	48.1	75	102

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 4    dsvtclaf.sd.tllvsGsdDgtikvWD 29
           +  +++++ +d ++++ GsdD ++ vW+
   Q: 75   SQSNSCRWsPDgKRFAFGSDDSSVSVWE 102
           56799****999***************9 PP

Organism

Caenorhabditis elegans

Functional Description
(View)

Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.

Protein Sequence
(Fasta)

MGDVYVTSPT FVGHDTGSIL AIDCHPSGKK FITCGQKART SNGLVVVWNA EPVLDKKKAS 60
NENVPKLLFQ VESQSQSNSC RWSPDGKRFA FGSDDSSVSV WEYVGLINSM GSITGGAQNV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGGGACG TATACGTCAC TTCACCTACA TTTGTTGGAC ATGATAGTGA GTTCTGTGTC 60
AAATATTCAA AAGTTTATAA AATATTTTCA GCTGGTTCAA TTCTAGCAAT CGACTGTCAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0025--Alternative splicing
KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0678--Repressor
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0853--WD repeat

Interpro

IPR031120--HIR1
IPR011494--Hira
IPR019015--HIRA_B_motif
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF07569--Hira
PF09453--HIRA_B
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0000790--C:nuclear chromatin
GO:0031491--F:nucleosome binding
GO:0003714--F:transcription corepressor activity
GO:0016569--P:covalent chromatin modification
GO:0006336--P:DNA replication-independent nucleosome assembly
GO:0031935--P:regulation of chromatin silencing
GO:0006351--P:transcription, DNA-templated

KEGG

cel:CELE_K10D2.1

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001039	Aegilops tauschii	27.32	1.00e-43	171.00
IUUC-Aml-001723	Ailuropoda melanoleuca	38.04	2.00e-70	259.00
IUUC-Atr-003132	Amborella trichopoda	27.78	1.00e-41	164.00
IUUC-Apl-003197	Anas platyrhynchos	38.04	9.00e-71	260.00
IUUC-Aca-004733	Anolis carolinensis	38.36	7.00e-73	267.00
IUUC-Aly-005446	Arabidopsis lyrata	26.34	3.00e-46	179.00
IUUC-Ath-007627	Arabidopsis thaliana	27.26	8.00e-47	181.00
IUUC-Ago-007766	Ashbya gossypii	26.01	2.00e-30	126.00
IUUC-Acl-008104	Aspergillus clavatus	23.92	2.00e-32	133.00
IUUC-Afl-008591	Aspergillus flavus	21.94	1.00e-30	127.00
IUUC-Afu-008781	Aspergillus fumigatus	25.00	8.00e-31	128.00
IUUC-Ani-009272	Aspergillus nidulans	24.36	1.00e-26	114.00
IUUC-Ang-009655	Aspergillus niger	24.87	4.00e-31	129.00
IUUC-Aor-010119	Aspergillus oryzae	21.94	2.00e-30	127.00
IUUC-Ate-010530	Aspergillus terreus	23.75	9.00e-26	111.00
IUUC-Bgr-012237	Blumeria graminis	25.27	4.00e-26	112.00
IUUC-Bta-013320	Bos taurus	38.26	7.00e-71	261.00
IUUC-Bci-013795	Botrytis cinerea	25.07	1.00e-31	130.00
IUUC-Bdi-014075	Brachypodium distachyon	27.48	3.00e-45	176.00
IUUC-Bol-016440	Brassica oleracea	25.80	8.00e-46	177.00
IUUC-Bra-016651	Brassica rapa	26.19	2.00e-45	176.00
IUUC-Cja-018987	Callithrix jacchus	37.31	4.00e-62	231.00
IUUC-Cfa-020132	Canis familiaris	38.04	2.00e-70	259.00
IUUC-Cpo-021484	Cavia porcellus	38.10	4.00e-73	268.00
IUUC-Cre-022846	Chlamydomonas reinhardtii	29.35	2.00e-42	166.00
IUUC-Csa-023081	Chlorocebus sabaeus	33.20	3.00e-73	268.00
IUUC-Cin-025182	Ciona intestinalis	35.83	2.00e-67	249.00
IUUC-Csv-026154	Ciona savignyi	31.77	1.00e-63	237.00
IUUC-Cgl-026655	Colletotrichum gloeosporioides	26.26	7.00e-32	131.00
IUUC-Cne-026891	Cryptococcus neoformans	32.74	6.00e-50	191.00
IUUC-Cme-027349	Cyanidioschyzon merolae	25.79	1.00e-26	114.00
IUUC-Dre-027655	Danio rerio	34.08	1.00e-73	270.00
IUUC-Dno-029557	Dasypus novemcinctus	32.08	2.00e-57	216.00
IUUC-Dor-030687	Dipodomys ordii	34.30	1.00e-55	210.00
IUUC-Dse-031334	Dothistroma septosporum	23.35	3.00e-28	119.00
IUUC-Dme-031746	Drosophila melanogaster	34.15	5.00e-75	275.00
IUUC-Ete-032384	Echinops telfairi	34.42	8.00e-56	211.00
IUUC-Eca-033430	Equus caballus	33.26	3.00e-71	262.00
IUUC-Fca-036121	Felis catus	38.04	2.00e-70	259.00
IUUC-Fal-036817	Ficedula albicollis	38.04	1.00e-70	259.00
IUUC-Fox-037906	Fusarium oxysporum	25.83	2.00e-32	132.00
IUUC-Fso-038409	Fusarium solani	23.98	4.00e-33	135.00
IUUC-Gmo-039151	Gadus morhua	36.54	9.00e-71	260.00
IUUC-Ggr-040016	Gaeumannomyces graminis	23.63	1.00e-31	130.00
IUUC-Gga-040936	Gallus gallus	38.10	2.00e-73	269.00
IUUC-Gac-041405	Gasterosteus aculeatus	37.87	1.00e-67	250.00
IUUC-Gma-044252	Glycine max	27.23	2.00e-43	169.00
IUUC-Ggo-045430	Gorilla gorilla	33.20	3.00e-73	268.00
IUUC-Hsa-046442	Homo sapiens	33.20	3.00e-73	268.00
IUUC-Hvu-047587	Hordeum vulgare	27.01	9.00e-39	154.00
IUUC-Itr-048910	Ictidomys tridecemlineatus	39.67	4.00e-59	219.00
IUUC-Kpa-049145	Komagataella pastoris	28.79	3.00e-31	129.00
IUUC-Lch-050474	Latimeria chalumnae	37.73	2.00e-69	256.00
IUUC-Lpe-051209	Leersia perrieri	26.46	3.00e-36	145.00
IUUC-Loc-052119	Lepisosteus oculatus	35.07	1.00e-74	273.00
IUUC-Lma-053237	Leptosphaeria maculans	24.18	7.00e-28	118.00
IUUC-Laf-053718	Loxodonta africana	34.16	2.00e-73	269.00
IUUC-Mcc-055621	Macaca mulatta	37.31	3.00e-62	232.00
IUUC-Meu-055914	Macropus eugenii	39.35	5.00e-54	205.00
IUUC-Mor-057090	Magnaporthe oryzae	24.13	1.00e-31	130.00
IUUC-Mpo-057364	Magnaporthe poae	21.24	2.00e-31	129.00
IUUC-Mtr-057744	Medicago truncatula	28.03	3.00e-44	172.00
IUUC-Mla-058914	Melampsora laricipopulina	24.75	2.00e-54	206.00
IUUC-Mga-060181	Meleagris gallopavo	38.04	8.00e-71	261.00
IUUC-Mvi-060432	Microbotryum violaceum	29.16	1.00e-42	167.00
IUUC-Mmr-060871	Microcebus murinus	33.40	3.00e-73	268.00
IUUC-Mdo-062301	Monodelphis domestica	34.16	8.00e-73	267.00
IUUC-Mmu-063888	Mus musculus	33.61	7.00e-74	271.00
IUUC-Mac-065137	Musa acuminata	29.03	7.00e-44	171.00
IUUC-Mpu-066732	Mustela putorius furo	37.83	1.00e-70	259.00
IUUC-Mlu-067542	Myotis lucifugus	33.54	7.00e-74	271.00
IUUC-Nfi-068396	Neosartorya fischeri	24.72	4.00e-30	125.00
IUUC-Ncr-068842	Neurospora crassa	25.37	8.00e-32	131.00
IUUC-Nle-070156	Nomascus leucogenys	38.10	4.00e-73	268.00
IUUC-Opr-070808	Ochotona princeps	37.65	2.00e-46	179.00
IUUC-Ont-072105	Oreochromis niloticus	34.15	4.00e-73	268.00
IUUC-Ocu-074962	Oryctolagus cuniculus	33.26	3.00e-71	262.00
IUUC-Oba-075178	Oryza barthii	26.72	2.00e-43	169.00
IUUC-Obr-076399	Oryza brachyantha	27.85	1.00e-44	174.00
IUUC-Ogu-078797	Oryza glumaepatula	26.72	2.00e-43	169.00
IUUC-Oin-080085	Oryza indica	26.88	2.00e-38	152.00
IUUC-Olo-081048	Oryza longistaminata	26.82	3.00e-33	136.00
IUUC-Ome-081324	Oryza meridionalis	26.72	2.00e-43	170.00
IUUC-Oni-082548	Oryza nivara	26.72	2.00e-43	170.00
IUUC-Opu-084008	Oryza punctata	27.59	6.00e-44	171.00
IUUC-Oru-084339	Oryza rufipogon	26.46	6.00e-43	168.00
IUUC-Osa-085782	Oryza sativa	26.46	6.00e-43	168.00
IUUC-Ola-087302	Oryzias latipes	32.58	2.00e-63	236.00
IUUC-Olu-087611	Ostreococcus lucimarinus	32.63	3.00e-53	202.00
IUUC-Oga-087935	Otolemur garnettii	33.19	1.00e-70	260.00
IUUC-Oar-089229	Ovis aries	32.80	5.00e-51	195.00
IUUC-Ptr-090715	Pan troglodytes	33.20	3.00e-73	268.00
IUUC-Pan-092318	Papio anubis	33.05	1.00e-70	259.00
IUUC-Psi-094053	Pelodiscus sinensis	37.57	4.00e-69	255.00
IUUC-Pno-094985	Phaeosphaeria nodorum	24.53	6.00e-25	108.00
IUUC-Ppa-095819	Physcomitrella patens	30.35	2.00e-46	179.00
IUUC-Pfo-096857	Poecilia formosa	33.88	1.00e-71	263.00
IUUC-Pab-098047	Pongo abelii	33.20	3.00e-73	268.00
IUUC-Pop-099587	Populus trichocarpa	28.75	1.00e-45	177.00
IUUC-Pca-100558	Procavia capensis	41.46	1.00e-42	167.00
IUUC-Ppe-101261	Prunus persica	25.48	1.00e-43	171.00
IUUC-Pva-102683	Pteropus vampyrus	33.20	3.00e-72	265.00
IUUC-Pgr-103660	Puccinia graminis	28.80	2.00e-40	159.00
IUUC-Ptt-103900	Puccinia triticina	31.51	4.00e-40	158.00
IUUC-Pte-104209	Pyrenophora teres	25.20	2.00e-28	119.00
IUUC-Pyt-104802	Pyrenophora triticirepentis	25.41	1.00e-27	117.00
IUUC-Rno-105566	Rattus norvegicus	33.61	7.00e-74	271.00
IUUC-Sce-106291	Saccharomyces cerevisiae	23.10	7.00e-27	114.00
IUUC-Sha-107514	Sarcophilus harrisii	36.49	3.00e-63	235.00
IUUC-Sja-107833	Schizosaccharomyces japonicus	23.89	4.00e-55	208.00
IUUC-Spo-108162	Schizosaccharomyces pombe	31.37	2.00e-44	173.00
IUUC-Smo-109186	Selaginella moellendorffii	29.03	6.00e-46	178.00
IUUC-Sit-109980	Setaria italica	28.75	2.00e-45	176.00
IUUC-Sly-111547	Solanum lycopersicum	27.92	7.00e-49	187.00
IUUC-Stu-112705	Solanum tuberosum	27.18	2.00e-48	187.00
IUUC-Sar-113222	Sorex araneus	31.70	2.00e-63	236.00
IUUC-Sbi-114272	Sorghum bicolor	28.75	2.00e-46	180.00
IUUC-Sre-115061	Sporisorium reilianum	27.01	3.00e-47	182.00
IUUC-Ssc-116364	Sus scrofa	33.26	7.00e-71	261.00
IUUC-Tgu-116645	Taeniopygia guttata	38.04	7.00e-71	261.00
IUUC-Tru-117590	Takifugu rubripes	34.58	1.00e-75	276.00
IUUC-Tsy-119212	Tarsius syrichta	38.89	1.00e-63	237.00
IUUC-Tni-119915	Tetraodon nigroviridis	34.24	2.00e-74	273.00
IUUC-Tca-121765	Theobroma cacao	25.86	2.00e-46	179.00
IUUC-Tre-121887	Trichoderma reesei	24.55	8.00e-26	111.00
IUUC-Tvi-122262	Trichoderma virens	23.77	9.00e-26	111.00
IUUC-Tur-126483	Triticum urartu	28.50	1.00e-46	180.00
IUUC-Tme-127202	Tuber melanosporum	27.30	3.00e-27	115.00
IUUC-Tbe-127350	Tupaia belangeri	31.98	7.00e-47	181.00
IUUC-Ttr-129077	Tursiops truncatus	30.82	8.00e-63	234.00
IUUC-Uma-129465	Ustilago maydis	25.48	8.00e-49	187.00
IUUC-Vda-129844	Verticillium dahliae	24.88	5.00e-33	135.00
IUUC-Vvi-131397	Vitis vinifera	26.33	2.00e-46	179.00
IUUC-Xtr-132057	Xenopus tropicalis	37.83	2.00e-72	266.00
IUUC-Xma-134139	Xiphophorus maculatus	37.61	3.00e-61	228.00
IUUC-Yli-134424	Yarrowia lipolytica	24.29	1.00e-31	130.00
IUUC-Zma-135839	Zea mays	28.21	1.00e-44	174.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence