iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-049827

Ensembl Protein ID

ENSLACP00000003730.2

UniProt Accession

H3A259; H3A259_LATCH

Genbank Protein ID

ENSLACP00000003730

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AFYH01102853

Gene Name

FZR1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000003322.2	ENSLACT00000003764.2	ENSLACP00000003730.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.20e-26	91.0	311	341
E3 adaptor/Cullin RING/APC_C/CDC20	9.20e-151	501.5	175	479

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWD 29
           gH  +v++l++ +d  ll+sG++D+++ vW+
   Q: 311  GHRQEVCGLKWsTDhQLLASGGNDNKLLVWN 341
           8**********98889**************9 PP

E3 adaptor/Cullin RING/APC_C/CDC20

   S: 1    pekvldapelrddfylnLldWssknvlavaLgssvylwsaktgdvskladl.eekdlvtsvswieegtllavGtkkgeveiyDveekkk 88
           p+kvldapel+ddfylnL+dWss nvl+v+Lg++vylwsa+t++v++l+dl  e+d+vtsv w+e+g+l+avGt+kg v+i+D+++ kk
   Q: 175  PFKVLDAPELQDDFYLNLVDWSSVNVLSVGLGTCVYLWSACTSQVTRLCDLsVEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAAAGKK 263
           689************************************************99************************************ PP
   S: 89   vrtltghsarvgaLsWnaevlssGsrdgeilhrdvrvkelkl.stlqahaqevCGlkwnedaklLasGGnDnsvsvwdasssePlkkfk 176
           ++tl+gh+arvgaL+Wna++lssGsrd++il+rd+r++ l+  ++lq+h+qevCGlkw++d++lLasGGnDn++ vw++ss +P+++++
   Q: 264  LSTLEGHTARVGALAWNADQLSSGSRDRMILQRDIRTPPLQSeRRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYT 352
           ******************************************99********************************************* PP
   S: 177  ehkaavkaiawsPwqkslLasGGGtaDrcikfwntltgalleeidtgsqvcsllwskkskelvsthGfaenkitlwkypslskvaelkg 265
           eh aavkaiawsP+q++lLasGGGtaDrci+fwntltg+ l++idtgsqvc+l+wsk+++elvsthG+++n+i +wkypsl++va+l+g
   Q: 353  EHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTG 441
           ***************************************************************************************** PP
   S: 266  heaRvlslalspdgeaivtaagDetlrfwklfdkkkak 303
           h++Rvl+la+spdgeaivt+agDetlrfw++f+k++++
   Q: 442  HSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRST 479
           *********************************99875 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

MDQDYERRLL RQINIQNENA SPCMPEMRRT LTPSNSPVSS PSKHGDRFIP SRAGANWSIN 60
FHRINENEKS PSQNRKAKDA TSDNGKDGLA YSALLKNELL GAGIEKIQDP QTEDRRLQPS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTCCTGTATT GTTTTGAATT ACCCCACGTC AGCGCGCGGC GCTGCGTGGC GTTGTACGTG 60
CGGAGGGAGA GGGGGGGGGT TAGCGTACAA TTTGGACGCC ATATTGAATG TCAGGAGAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR033010--Cdc20/Fizzy
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0097027--F:ubiquitin-protein transferase activator activity
GO:1904668--P:positive regulation of ubiquitin protein ligase activity

KEGG

lcm:102348914

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000670	Aegilops tauschii	64.52	4.00e-115	408.00
IUUC-Aml-002003	Ailuropoda melanoleuca	92.14	0.00e+00	909.00
IUUC-Atr-002753	Amborella trichopoda	57.66	6.00e-134	470.00
IUUC-Apl-003212	Anas platyrhynchos	97.36	0.00e+00	975.00
IUUC-Aly-005442	Arabidopsis lyrata	57.57	1.00e-139	489.00
IUUC-Ath-006938	Arabidopsis thaliana	57.89	1.00e-138	486.00
IUUC-Ago-007784	Ashbya gossypii	49.71	2.00e-97	349.00
IUUC-Acl-008269	Aspergillus clavatus	49.79	2.00e-133	468.00
IUUC-Afl-008432	Aspergillus flavus	50.42	1.00e-132	466.00
IUUC-Afu-008829	Aspergillus fumigatus	50.21	9.00e-134	470.00
IUUC-Ani-009471	Aspergillus nidulans	50.42	1.00e-132	466.00
IUUC-Ang-009711	Aspergillus niger	50.95	2.00e-131	462.00
IUUC-Aor-010118	Aspergillus oryzae	50.42	1.00e-132	466.00
IUUC-Ate-010534	Aspergillus terreus	50.52	5.00e-132	464.00
IUUC-Ame-011011	Astyanax mexicanus	92.76	0.00e+00	887.00
IUUC-Bgr-012013	Blumeria graminis	50.71	3.00e-131	462.00
IUUC-Bta-012586	Bos taurus	96.75	0.00e+00	970.00
IUUC-Bci-013807	Botrytis cinerea	51.95	5.00e-126	444.00
IUUC-Bdi-014981	Brachypodium distachyon	54.79	9.00e-131	460.00
IUUC-Bol-016301	Brassica oleracea	57.01	3.00e-138	484.00
IUUC-Bra-017453	Brassica rapa	57.01	2.00e-138	485.00
IUUC-Cel-018472	Caenorhabditis elegans	65.33	4.00e-143	501.00
IUUC-Cja-019929	Callithrix jacchus	95.97	0.00e+00	960.00
IUUC-Cfa-020977	Canis familiaris	95.97	0.00e+00	963.00
IUUC-Cpo-021537	Cavia porcellus	96.75	0.00e+00	969.00
IUUC-Cre-022701	Chlamydomonas reinhardtii	46.29	2.00e-93	335.00
IUUC-Csa-023389	Chlorocebus sabaeus	96.35	0.00e+00	965.00
IUUC-Cin-025327	Ciona intestinalis	70.09	0.00e+00	631.00
IUUC-Csv-025921	Ciona savignyi	66.79	0.00e+00	672.00
IUUC-Cgl-026631	Colletotrichum gloeosporioides	51.42	6.00e-133	468.00
IUUC-Cne-026933	Cryptococcus neoformans	59.84	7.00e-128	451.00
IUUC-Cme-027143	Cyanidioschyzon merolae	63.37	3.00e-117	416.00
IUUC-Dre-027470	Danio rerio	91.73	0.00e+00	881.00
IUUC-Dno-029629	Dasypus novemcinctus	87.20	0.00e+00	780.00
IUUC-Dor-030187	Dipodomys ordii	85.89	0.00e+00	856.00
IUUC-Dse-031502	Dothistroma septosporum	50.64	1.00e-126	446.00
IUUC-Dme-031858	Drosophila melanogaster	74.22	0.00e+00	683.00
IUUC-Ete-032562	Echinops telfairi	83.98	0.00e+00	815.00
IUUC-Eca-034210	Equus caballus	96.55	0.00e+00	969.00
IUUC-Fca-035839	Felis catus	91.28	0.00e+00	914.00
IUUC-Fal-036895	Ficedula albicollis	97.16	0.00e+00	973.00
IUUC-Fox-037814	Fusarium oxysporum	64.60	2.00e-124	437.00
IUUC-Fso-038420	Fusarium solani	50.31	1.00e-132	466.00
IUUC-Gmo-039544	Gadus morhua	90.54	0.00e+00	863.00
IUUC-Ggr-039774	Gaeumannomyces graminis	51.12	3.00e-132	465.00
IUUC-Gga-041025	Gallus gallus	97.16	0.00e+00	973.00
IUUC-Gac-041596	Gasterosteus aculeatus	91.13	0.00e+00	875.00
IUUC-Gma-042657	Glycine max	53.83	7.00e-136	476.00
IUUC-Ggo-045599	Gorilla gorilla	95.97	0.00e+00	925.00
IUUC-Hsa-046695	Homo sapiens	95.77	0.00e+00	959.00
IUUC-Hvu-047486	Hordeum vulgare	65.95	8.00e-107	379.00
IUUC-Itr-048192	Ictidomys tridecemlineatus	95.54	0.00e+00	963.00
IUUC-Kpa-049239	Komagataella pastoris	58.50	2.00e-122	432.00
IUUC-Lpe-051568	Leersia perrieri	51.14	1.00e-111	396.00
IUUC-Loc-052856	Lepisosteus oculatus	95.76	0.00e+00	922.00
IUUC-Laf-054321	Loxodonta africana	61.11	2.00e-145	508.00
IUUC-Mcc-055601	Macaca mulatta	96.35	0.00e+00	965.00
IUUC-Meu-056276	Macropus eugenii	68.12	7.00e-170	589.00
IUUC-Mor-057113	Magnaporthe oryzae	51.55	1.00e-132	466.00
IUUC-Mpo-057599	Magnaporthe poae	51.64	2.00e-132	465.00
IUUC-Mtr-057689	Medicago truncatula	56.89	4.00e-137	481.00
IUUC-Mla-059048	Melampsora laricipopulina	50.10	3.00e-120	425.00
IUUC-Mga-060097	Meleagris gallopavo	91.15	0.00e+00	901.00
IUUC-Mvi-060465	Microbotryum violaceum	52.18	1.00e-130	460.00
IUUC-Mmr-061151	Microcebus murinus	87.10	0.00e+00	834.00
IUUC-Mdo-063062	Monodelphis domestica	96.96	0.00e+00	973.00
IUUC-Mmu-063731	Mus musculus	96.75	0.00e+00	968.00
IUUC-Mac-065208	Musa acuminata	58.16	8.00e-131	460.00
IUUC-Mpu-066173	Mustela putorius furo	96.15	0.00e+00	964.00
IUUC-Mlu-068030	Myotis lucifugus	96.37	0.00e+00	964.00
IUUC-Nfi-068536	Neosartorya fischeri	50.21	2.00e-134	472.00
IUUC-Ncr-068734	Neurospora crassa	52.56	6.00e-135	474.00
IUUC-Nle-070163	Nomascus leucogenys	96.35	0.00e+00	966.00
IUUC-Opr-070974	Ochotona princeps	91.10	7.00e-155	539.00
IUUC-Ont-072272	Oreochromis niloticus	90.20	0.00e+00	867.00
IUUC-Oan-073634	Ornithorhynchus anatinus	98.98	3.00e-174	603.00
IUUC-Oba-075417	Oryza barthii	62.86	4.00e-111	394.00
IUUC-Obr-076123	Oryza brachyantha	69.84	1.00e-126	446.00
IUUC-Ogl-077294	Oryza glaberrima	53.88	5.00e-128	451.00
IUUC-Ogu-077996	Oryza glumaepatula	53.66	1.00e-126	446.00
IUUC-Oin-080172	Oryza indica	70.49	1.00e-126	446.00
IUUC-Olo-081068	Oryza longistaminata	70.49	1.00e-126	445.00
IUUC-Ome-081250	Oryza meridionalis	54.34	4.00e-129	454.00
IUUC-Oni-083048	Oryza nivara	53.88	5.00e-128	451.00
IUUC-Opu-083333	Oryza punctata	54.29	3.00e-128	452.00
IUUC-Oru-085001	Oryza rufipogon	53.88	5.00e-128	451.00
IUUC-Osa-086243	Oryza sativa	53.88	5.00e-128	451.00
IUUC-Ola-087094	Oryzias latipes	89.62	0.00e+00	828.00
IUUC-Olu-087647	Ostreococcus lucimarinus	52.68	5.00e-98	351.00
IUUC-Oga-088911	Otolemur garnettii	96.96	0.00e+00	970.00
IUUC-Oar-089508	Ovis aries	96.75	0.00e+00	970.00
IUUC-Ptr-090967	Pan troglodytes	82.99	0.00e+00	633.00
IUUC-Pan-092147	Papio anubis	95.77	0.00e+00	959.00
IUUC-Psi-093702	Pelodiscus sinensis	96.77	0.00e+00	967.00
IUUC-Pma-094581	Petromyzon marinus	85.06	0.00e+00	813.00
IUUC-Pno-095139	Phaeosphaeria nodorum	60.06	2.00e-113	403.00
IUUC-Ppa-095366	Physcomitrella patens	58.78	1.00e-140	493.00
IUUC-Pfo-096309	Poecilia formosa	91.13	0.00e+00	874.00
IUUC-Pab-098762	Pongo abelii	78.63	0.00e+00	736.00
IUUC-Pop-098924	Populus trichocarpa	56.52	9.00e-133	466.00
IUUC-Pca-100565	Procavia capensis	91.54	0.00e+00	862.00
IUUC-Ppe-101924	Prunus persica	57.34	4.00e-137	481.00
IUUC-Pva-102602	Pteropus vampyrus	93.74	0.00e+00	921.00
IUUC-Pgr-103466	Puccinia graminis	50.86	1.00e-118	420.00
IUUC-Ptt-103888	Puccinia triticina	53.96	2.00e-108	386.00
IUUC-Pte-104097	Pyrenophora teres	49.12	2.00e-129	456.00
IUUC-Pyt-104445	Pyrenophora triticirepentis	45.40	2.00e-111	396.00
IUUC-Rno-105028	Rattus norvegicus	96.55	0.00e+00	966.00
IUUC-Sce-106240	Saccharomyces cerevisiae	39.31	3.00e-96	345.00
IUUC-Sha-107107	Sarcophilus harrisii	83.00	0.00e+00	813.00
IUUC-Sja-107900	Schizosaccharomyces japonicus	48.87	9.00e-116	409.00
IUUC-Spo-108056	Schizosaccharomyces pombe	48.73	1.00e-114	406.00
IUUC-Ssl-108391	Sclerotinia sclerotiorum	53.00	6.00e-129	454.00
IUUC-Smo-108878	Selaginella moellendorffii	59.28	2.00e-145	509.00
IUUC-Sit-110563	Setaria italica	54.87	3.00e-123	435.00
IUUC-Sly-111446	Solanum lycopersicum	56.07	5.00e-135	474.00
IUUC-Stu-112491	Solanum tuberosum	55.88	3.00e-134	471.00
IUUC-Sar-112962	Sorex araneus	80.15	3.00e-119	420.00
IUUC-Sbi-114489	Sorghum bicolor	54.99	1.00e-125	442.00
IUUC-Sre-115222	Sporisorium reilianum	48.02	1.00e-132	466.00
IUUC-Ssc-116171	Sus scrofa	96.75	0.00e+00	970.00
IUUC-Tgu-116878	Taeniopygia guttata	85.63	0.00e+00	833.00
IUUC-Tru-118222	Takifugu rubripes	89.78	0.00e+00	863.00
IUUC-Tni-119863	Tetraodon nigroviridis	90.52	0.00e+00	863.00
IUUC-Tca-121599	Theobroma cacao	57.47	2.00e-134	472.00
IUUC-Tre-122249	Trichoderma reesei	51.74	2.00e-134	472.00
IUUC-Tvi-122675	Trichoderma virens	51.32	5.00e-134	471.00
IUUC-Tae-123489	Triticum aestivum	55.01	7.00e-130	457.00
IUUC-Tur-126545	Triticum urartu	59.94	4.00e-104	371.00
IUUC-Tme-127151	Tuber melanosporum	54.77	8.00e-145	506.00
IUUC-Tbe-128056	Tupaia belangeri	88.12	6.00e-166	576.00
IUUC-Ttr-129055	Tursiops truncatus	95.16	0.00e+00	947.00
IUUC-Uma-129555	Ustilago maydis	47.83	5.00e-132	464.00
IUUC-Vda-130027	Verticillium dahliae	51.54	2.00e-134	472.00
IUUC-Vvi-131749	Vitis vinifera	55.53	7.00e-135	473.00
IUUC-Xtr-132808	Xenopus tropicalis	91.48	0.00e+00	915.00
IUUC-Xma-133183	Xiphophorus maculatus	91.13	0.00e+00	874.00
IUUC-Yli-134584	Yarrowia lipolytica	64.84	1.00e-131	463.00
IUUC-Zma-135640	Zea mays	53.91	2.00e-126	445.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence