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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Mmu-063567
Ensembl Protein ID ENSMUSP00000003345.7
UniProt Accession Q7TQF7; Q8R1C4; AMPH_MOUSE
Genbank Protein ID AAH24817.1; AAH54718.1
Protein Name Amphiphysin
Genbank Nucleotide ID BC024817; BC054718
Gene Name Amph; Amph1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000021314.11 ENSMUST00000200466.4 ENSMUSP00000142766.1
ENSMUSG00000021314.11 ENSMUST00000003345.8 ENSMUSP00000003345.7
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
AREsitemiRTarBasemicroRNATRANSFAC
RepTarmiRNAMapRAID2
Protein-protein Interaction
IIDiRefIndexHINTMentha
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusdbPTM
Phospho.ELMUniProtPHOSIDAmUbiSiDa
Protein Expression/Proteomics
GPMDB
Status Reviewed
Details
Family Domain References (PMIDs)
UBD/SH3 SH3 17244534
Classification
Family E-value Score Start End
UBD/SH3 2.10e-23 83.1 614 686
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/SH3
   S: 2    skekvqvlydyeaqnddeLtlkkGdvvlvi...ekeeqdegWlkgvk........elegkrGlfPenFvekle 63
           +++kv++l+d+ea+n+deL+l++Gdvvlv+   ++++qd+gWl+gvk        +l++++GlfPenF+++le
   Q: 614  FLYKVETLHDFEAANSDELNLQRGDVVLVVpsdSEADQDAGWLVGVKesdwlqyrDLATYKGLFPENFTRRLE 686
           789*******************************************************************985 PP
   
Organism Mus musculus
Functional Description
(View)

Functional Description


     May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton (By similarity).
 May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton (By similarity).
Protein Sequence
(Fasta)
MADIKTGIFA KNVQKRLNRA QEKVLQKLGK ADETKDEQFE EYVQNFKRQE AEGTRLQREL 60
RGYLAAIKGM QEASMKLTES LHEVYEPDWY GREDVKMVGE KCDVLWEDFH QKLVDGSLLT 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-063567|UBD,SH3|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CTCCTTCTCT TCCTGGGCTC CTCGGTGCCG CCGCCGGCTC GCTGCGCGCT CTGCTCTTCC 60
AGCTCTGCGG ACCGCAGCAG CCATGGCCGA CATCAAGACG GGCATCTTCG CCAAAAACGT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-063567|UBD,SH3|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0965--Cell junction
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0968--Cytoplasmic vesicle
KW-0206--Cytoskeleton
KW-0472--Membrane
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0770--Synapse
Interpro

IPR027267--AH/BAR-dom
IPR003005--Amphiphysin
IPR003017--Amphiphysin_1
IPR004148--BAR_dom
IPR001452--SH3_domain
PROSITE

PS51021--BAR
PS50002--SH3
Pfam

PF03114--BAR
PF14604--SH3_9
PRINTS

PR01251--AMPHIPHYSIN
PR01252--AMPHIPHYSIN1
PR00452--SH3DOMAIN
SMART

SM00721--BAR
SM00326--SH3
Gene Ontology

GO:0030054--C:cell junction
GO:0005856--C:cytoskeleton
GO:0031256--C:leading edge membrane
GO:0008021--C:synaptic vesicle
GO:0030672--C:synaptic vesicle membrane
GO:0005543--F:phospholipid binding
GO:0007612--P:learning
GO:0048488--P:synaptic vesicle endocytosis
KEGG mmu:218038
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001261 Ailuropoda melanoleuca 82.73 0.00e+00 900.00
IUUC-Apl-003820 Anas platyrhynchos 85.61 0.00e+00 631.00
IUUC-Aca-004603 Anolis carolinensis 68.79 0.00e+00 795.00
IUUC-Acl-008143 Aspergillus clavatus 28.17 2.00e-17 82.80
IUUC-Afu-008953 Aspergillus fumigatus 30.00 1.00e-18 86.70
IUUC-Ani-009357 Aspergillus nidulans 29.05 9.00e-16 76.60
IUUC-Ang-009877 Aspergillus niger 29.02 1.00e-17 83.60
IUUC-Ate-010244 Aspergillus terreus 29.13 3.00e-18 85.50
IUUC-Ame-010666 Astyanax mexicanus 65.19 1.00e-135 477.00
IUUC-Bgr-012176 Blumeria graminis 28.91 3.00e-17 82.00
IUUC-Bta-013010 Bos taurus 80.84 0.00e+00 898.00
IUUC-Bci-013618 Botrytis cinerea 30.45 4.00e-18 84.70
IUUC-Cel-018166 Caenorhabditis elegans 34.30 4.00e-40 159.00
IUUC-Cja-019833 Callithrix jacchus 81.69 0.00e+00 946.00
IUUC-Cfa-021194 Canis familiaris 79.05 0.00e+00 893.00
IUUC-Cpo-021536 Cavia porcellus 80.18 0.00e+00 822.00
IUUC-Cre-022932 Chlamydomonas reinhardtii 33.33 2.20e-02 32.30
IUUC-Csa-023774 Chlorocebus sabaeus 81.85 0.00e+00 824.00
IUUC-Cho-024492 Choloepus hoffmanni 82.06 7.00e-142 498.00
IUUC-Cin-025739 Ciona intestinalis 34.45 1.00e-41 164.00
IUUC-Csv-026073 Ciona savignyi 36.78 7.00e-47 181.00
IUUC-Dre-028065 Danio rerio 68.57 2.00e-135 476.00
IUUC-Dno-029023 Dasypus novemcinctus 93.18 4.00e-159 555.00
IUUC-Dor-030535 Dipodomys ordii 85.75 8.00e-166 577.00
IUUC-Dse-031269 Dothistroma septosporum 28.18 1.00e-17 83.20
IUUC-Dme-032153 Drosophila melanogaster 40.51 6.00e-54 205.00
IUUC-Ete-032623 Echinops telfairi 83.43 5.00e-140 491.00
IUUC-Eca-033701 Equus caballus 80.65 0.00e+00 887.00
IUUC-Eeu-034674 Erinaceus europaeus 97.51 1.00e-154 540.00
IUUC-Fca-035827 Felis catus 77.66 0.00e+00 816.00
IUUC-Fal-036846 Ficedula albicollis 85.49 6.00e-133 468.00
IUUC-Fox-037819 Fusarium oxysporum 29.79 2.00e-19 89.70
IUUC-Gmo-038933 Gadus morhua 67.66 1.00e-125 443.00
IUUC-Gga-041211 Gallus gallus 87.14 0.00e+00 683.00
IUUC-Gac-041862 Gasterosteus aculeatus 61.23 8.00e-128 451.00
IUUC-Ggo-045200 Gorilla gorilla 84.12 0.00e+00 989.00
IUUC-Hsa-046142 Homo sapiens 84.65 0.00e+00 996.00
IUUC-Itr-048747 Ictidomys tridecemlineatus 81.20 0.00e+00 844.00
IUUC-Loc-052158 Lepisosteus oculatus 77.52 5.00e-157 548.00
IUUC-Lma-053251 Leptosphaeria maculans 27.96 3.00e-19 89.00
IUUC-Laf-054138 Loxodonta africana 79.14 0.00e+00 940.00
IUUC-Mcc-055712 Macaca mulatta 83.36 0.00e+00 944.00
IUUC-Meu-056810 Macropus eugenii 69.32 2.00e-98 353.00
IUUC-Mla-058828 Melampsora laricipopulina 27.40 5.00e-21 94.70
IUUC-Mvi-060216 Microbotryum violaceum 24.65 3.00e-15 75.50
IUUC-Mmr-060725 Microcebus murinus 80.49 0.00e+00 927.00
IUUC-Mdo-062060 Monodelphis domestica 88.74 0.00e+00 650.00
IUUC-Mpu-066178 Mustela putorius furo 80.68 0.00e+00 878.00
IUUC-Mlu-068015 Myotis lucifugus 95.74 0.00e+00 647.00
IUUC-Ncr-068637 Neurospora crassa 30.91 1.00e-17 83.20
IUUC-Nle-069053 Nomascus leucogenys 84.79 0.00e+00 1001.00
IUUC-Opr-070978 Ochotona princeps 79.06 1.00e-112 401.00
IUUC-Ont-072062 Oreochromis niloticus 64.93 1.00e-128 454.00
IUUC-Oan-073435 Ornithorhynchus anatinus 90.66 0.00e+00 681.00
IUUC-Ocu-073813 Oryctolagus cuniculus 81.72 0.00e+00 868.00
IUUC-Ola-086692 Oryzias latipes 57.67 3.00e-106 379.00
IUUC-Oga-088339 Otolemur garnettii 81.49 0.00e+00 820.00
IUUC-Oar-090177 Ovis aries 78.38 0.00e+00 876.00
IUUC-Ptr-091411 Pan troglodytes 84.65 0.00e+00 998.00
IUUC-Pan-091792 Papio anubis 82.83 0.00e+00 934.00
IUUC-Psi-093054 Pelodiscus sinensis 85.03 7.00e-156 543.00
IUUC-Pma-094171 Petromyzon marinus 61.83 2.00e-122 433.00
IUUC-Pno-094918 Phaeosphaeria nodorum 27.96 2.00e-19 89.70
IUUC-Pfo-097291 Poecilia formosa 68.73 1.00e-105 376.00
IUUC-Pab-098558 Pongo abelii 83.36 0.00e+00 1000.00
IUUC-Pva-103023 Pteropus vampyrus 85.60 2.00e-163 570.00
IUUC-Ptt-103759 Puccinia triticina 26.47 1.00e-14 72.80
IUUC-Pte-104041 Pyrenophora teres 27.96 3.00e-19 88.60
IUUC-Rno-105656 Rattus norvegicus 92.26 0.00e+00 991.00
IUUC-Sha-106518 Sarcophilus harrisii 74.04 0.00e+00 786.00
IUUC-Spo-108153 Schizosaccharomyces pombe 27.07 1.00e-15 77.00
IUUC-Ssl-108407 Sclerotinia sclerotiorum 30.45 4.00e-18 84.70
IUUC-Smo-108832 Selaginella moellendorffii 30.49 2.40e-02 34.70
IUUC-Sar-113003 Sorex araneus 84.85 6.00e-162 564.00
IUUC-Ssc-115617 Sus scrofa 82.14 0.00e+00 886.00
IUUC-Tgu-117450 Taeniopygia guttata 87.53 0.00e+00 668.00
IUUC-Tru-118595 Takifugu rubripes 64.66 1.00e-118 419.00
IUUC-Tsy-119402 Tarsius syrichta 87.31 2.00e-168 586.00
IUUC-Tni-120824 Tetraodon nigroviridis 63.45 9.00e-122 431.00
IUUC-Tre-121889 Trichoderma reesei 30.00 1.00e-20 93.60
IUUC-Tbe-127836 Tupaia belangeri 80.46 2.00e-164 572.00
IUUC-Ttr-129272 Tursiops truncatus 96.38 0.00e+00 640.00
IUUC-Vda-129687 Verticillium dahliae 27.88 2.00e-11 63.50
IUUC-Vpa-130758 Vicugna pacos 96.45 0.00e+00 632.00
IUUC-Xtr-132779 Xenopus tropicalis 67.27 4.00e-139 488.00
IUUC-Yli-134343 Yarrowia lipolytica 26.64 5.00e-16 78.20
Created Date 25-Jun-2017

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