iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
Protein-protein Interaction
iRefIndex	PINA	HINT	Mentha
Post-translational Modifications (PTMs)
dbPPT
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.00e-25	89.6	575	612

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sd.tllvsGsdDgtikvWDlrtgvll 36
           H+ +v+++++   d tll+sGsdDg++k+W++ +gv++
   Q: 575  HEKRVWSIDYssADpTLLASGSDDGSVKLWSINQGVSI 612
           9999*******9667****************9999875 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

Repressor of photomorphogenesis in the light. Probably part of the COP1/SPA E3 ubiquitin-protein ligase complex.

Protein Sequence
(Fasta)

MKGSSESSSR GLNNTSGVSE FCTDGSKSLS HIDYVRSLLG SHKEANLGGL DDDSIVRALE 60
CEDVSLRQWL DNPDRSVDAF ECFHVFRQIV EIVNAAHSQG IVVHNVRPSC FVMSSFNNVS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCAAAACCAA AATACGAAAA AGGTTTTAGC TTTACGTTCT TTTGATTCCT AGGTCGTCGT 60
TTAACCACGT TGCTTGCGTG GAAAGAGAAG AGAAGTGAAG ATTATCAAAA AGCGAAAAAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-0539--Nucleus
KW-0607--Phytochrome signaling pathway
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0833--Ubl conjugation pathway
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50011--PROTEIN_KINASE_DOM
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00220--S_TKc
SM00320--WD40

Gene Ontology

GO:0080008--C:Cul4-RING E3 ubiquitin ligase complex
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0042802--F:identical protein binding
GO:0004672--F:protein kinase activity
GO:0009585--P:red, far-red light phototransduction
GO:0009637--P:response to blue light

KEGG

ath:AT1G53090

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Atr-002923	Amborella trichopoda	62.23	0.00e+00	818.00
IUUC-Aly-005910	Arabidopsis lyrata	93.60	0.00e+00	1401.00
IUUC-Bdi-014444	Brachypodium distachyon	57.56	0.00e+00	771.00
IUUC-Bol-015644	Brassica oleracea	82.71	0.00e+00	1235.00
IUUC-Hvu-047820	Hordeum vulgare	56.63	0.00e+00	803.00
IUUC-Lpe-051099	Leersia perrieri	59.57	0.00e+00	717.00
IUUC-Mac-064599	Musa acuminata	56.08	0.00e+00	724.00
IUUC-Oba-075434	Oryza barthii	56.85	0.00e+00	753.00
IUUC-Obr-076666	Oryza brachyantha	58.03	0.00e+00	800.00
IUUC-Ogl-077203	Oryza glaberrima	58.03	0.00e+00	796.00
IUUC-Ogu-078753	Oryza glumaepatula	54.60	0.00e+00	684.00
IUUC-Oin-079226	Oryza indica	55.63	0.00e+00	753.00
IUUC-Olo-080700	Oryza longistaminata	57.64	3.00e-170	591.00
IUUC-Oni-082327	Oryza nivara	57.50	0.00e+00	791.00
IUUC-Opu-083945	Oryza punctata	59.97	0.00e+00	718.00
IUUC-Oru-085079	Oryza rufipogon	57.33	0.00e+00	791.00
IUUC-Sit-110040	Setaria italica	56.78	0.00e+00	726.00
IUUC-Sbi-114141	Sorghum bicolor	57.66	0.00e+00	765.00
IUUC-Tae-125217	Triticum aestivum	56.32	0.00e+00	778.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence