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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Hsa-046541
Ensembl Protein ID ENSP00000265107.4
UniProt Accession Q9NW82; Q9H053; WDR70_HUMAN
Genbank Protein ID BAA91502.1; CAC21644.1; AAH09648.1; AAH25315.1
Protein Name WD repeat-containing protein 70
Genbank Nucleotide ID AK001095; AL512685; BC009648; BC025315
Gene Name WDR70
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000082068.8 ENST00000265107.8 ENSP00000265107.4
ENSG00000082068.8 ENST00000504564.1 ENSP00000425841.1
Annotation
Cancer Mutation
TCGAICGCCOSMICCGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressTCGAICGC
COSMICTHPAHPM
DNA & RNA Element
UTRdbcircBasecircRNADbCircNet
miRTarBasemicroRNATRANSFACTargetScan
RepTarmiRNAMapSomamiRmiRcode
RAID2
Protein-protein Interaction
IIDiRefIndexPINAHINT
MenthaInWeb_IM
Disease-associated Variation
GWASdbOMIM
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusdbPTM
HPRDPhospho.ELMUniProtPHOSIDA
BioGRIDmUbiSiDa
DNA Methylation
TCGAICGCCOSMIC
Protein Expression/Proteomics
THPAHPMGPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 1.90e-12 48.5 382 412
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 7    tclaf.sd.tllvs.GsdDgtikvWDlrtgvl 35
           +c+ f  d + l+s G+dD ++k+WD+r++++
   Q: 382  SCVTFsYDgNVLASrGGDD-SLKLWDIRQFNK 412
           69999955599***66666.******999876 PP
   
Organism Homo sapiens
Protein Sequence
(Fasta)
MERSGPSEVT GSDASGPDPQ LAVTMGFTGF GKKARTFDLE AMFEQTRRTA VERSRKTLEA 60
REKEEEMNRE KELRRQNEDI EPTSSRSNVV RDCSKSSSRD TSSSESEQSS DSSDDELIGP 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Hsa-046541|E3,WD_repeat|Homo sapiens
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CGCGGTCCCT CTGCGGAAGG CGCCGCTCTT GGCTTCGGCG GCGCCGCTGT AGCTTGAAGG 60
CGGTACTTCC TCCAGCATTT GCCGCAAGTT ATTGGCAAGT TCCCCTGCAG TTGTTTGGGC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Hsa-046541|E3,WD_repeat|Homo sapiens
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0007--Acetylation
KW-0181--Complete proteome
KW-1017--Isopeptide bond
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0832--Ubl conjugation
KW-0853--WD repeat
Interpro

IPR027295--Quinoprotein_ADH-like_fam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF00400--WD40
SMART

SM00320--WD40
Gene Ontology

GO:0019899--F:enzyme binding
KEGG hsa:55100
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000150 Aegilops tauschii 41.38 9.00e-119 421.00
IUUC-Aml-002098 Ailuropoda melanoleuca 97.70 0.00e+00 677.00
IUUC-Atr-002886 Amborella trichopoda 42.89 2.00e-113 402.00
IUUC-Apl-004059 Anas platyrhynchos 74.96 0.00e+00 789.00
IUUC-Aca-004427 Anolis carolinensis 72.14 0.00e+00 868.00
IUUC-Aly-006122 Arabidopsis lyrata 41.95 7.00e-109 388.00
IUUC-Ath-006952 Arabidopsis thaliana 43.56 6.00e-107 381.00
IUUC-Acl-008150 Aspergillus clavatus 29.81 1.00e-58 221.00
IUUC-Afl-008722 Aspergillus flavus 29.75 9.00e-60 224.00
IUUC-Afu-009003 Aspergillus fumigatus 30.13 3.00e-60 226.00
IUUC-Ani-009306 Aspergillus nidulans 30.52 2.00e-58 220.00
IUUC-Ang-009780 Aspergillus niger 30.06 7.00e-58 218.00
IUUC-Aor-010109 Aspergillus oryzae 29.75 9.00e-60 224.00
IUUC-Ate-010484 Aspergillus terreus 30.90 2.00e-60 226.00
IUUC-Ame-011248 Astyanax mexicanus 70.50 0.00e+00 837.00
IUUC-Bgr-012093 Blumeria graminis 31.74 1.00e-63 237.00
IUUC-Bta-013581 Bos taurus 94.50 0.00e+00 1113.00
IUUC-Bci-013900 Botrytis cinerea 30.37 1.00e-60 227.00
IUUC-Bdi-014951 Brachypodium distachyon 42.23 3.00e-120 426.00
IUUC-Bol-016482 Brassica oleracea 42.33 1.00e-106 380.00
IUUC-Bra-016976 Brassica rapa 41.76 3.00e-107 382.00
IUUC-Cel-018229 Caenorhabditis elegans 37.60 2.00e-96 346.00
IUUC-Cja-019101 Callithrix jacchus 92.64 0.00e+00 1068.00
IUUC-Cfa-020638 Canis familiaris 95.11 0.00e+00 1138.00
IUUC-Cpo-022323 Cavia porcellus 94.58 0.00e+00 1129.00
IUUC-Csa-023743 Chlorocebus sabaeus 98.17 0.00e+00 1175.00
IUUC-Cho-024356 Choloepus hoffmanni 77.30 3.00e-128 452.00
IUUC-Cin-025151 Ciona intestinalis 50.41 1.00e-173 603.00
IUUC-Csv-025820 Ciona savignyi 57.51 2.00e-169 589.00
IUUC-Cgl-026404 Colletotrichum gloeosporioides 31.69 5.00e-64 238.00
IUUC-Cne-026790 Cryptococcus neoformans 42.22 2.00e-92 333.00
IUUC-Dno-029526 Dasypus novemcinctus 93.86 0.00e+00 1117.00
IUUC-Dse-031347 Dothistroma septosporum 32.12 6.00e-68 251.00
IUUC-Dme-032052 Drosophila melanogaster 51.14 1.00e-154 540.00
IUUC-Ete-032851 Echinops telfairi 96.10 8.00e-169 586.00
IUUC-Fca-035931 Felis catus 94.50 0.00e+00 1134.00
IUUC-Fal-037139 Ficedula albicollis 75.04 0.00e+00 904.00
IUUC-Fox-037696 Fusarium oxysporum 31.85 8.00e-64 238.00
IUUC-Fso-038349 Fusarium solani 32.04 8.00e-65 241.00
IUUC-Gmo-039027 Gadus morhua 79.74 0.00e+00 780.00
IUUC-Ggr-039982 Gaeumannomyces graminis 31.58 8.00e-53 201.00
IUUC-Gga-041080 Gallus gallus 74.49 0.00e+00 884.00
IUUC-Gac-041296 Gasterosteus aculeatus 68.04 0.00e+00 840.00
IUUC-Gma-044316 Glycine max 45.25 2.00e-117 416.00
IUUC-Ggo-045123 Gorilla gorilla 94.90 0.00e+00 921.00
IUUC-Itr-048403 Ictidomys tridecemlineatus 94.96 0.00e+00 1145.00
IUUC-Lch-050163 Latimeria chalumnae 82.45 0.00e+00 805.00
IUUC-Lpe-051614 Leersia perrieri 44.82 1.00e-114 407.00
IUUC-Loc-052721 Lepisosteus oculatus 69.78 0.00e+00 884.00
IUUC-Lma-053034 Leptosphaeria maculans 30.77 5.00e-59 222.00
IUUC-Laf-053704 Loxodonta africana 95.31 0.00e+00 1107.00
IUUC-Mcc-055688 Macaca mulatta 98.17 0.00e+00 1176.00
IUUC-Mor-057275 Magnaporthe oryzae 32.73 9.00e-59 221.00
IUUC-Mpo-057450 Magnaporthe poae 32.04 1.00e-61 230.00
IUUC-Mtr-057970 Medicago truncatula 43.80 1.00e-114 407.00
IUUC-Mla-059172 Melampsora laricipopulina 42.53 8.00e-107 381.00
IUUC-Mvi-060266 Microbotryum violaceum 40.00 6.00e-99 355.00
IUUC-Mmr-061611 Microcebus murinus 96.64 0.00e+00 1129.00
IUUC-Mdo-062609 Monodelphis domestica 79.39 0.00e+00 945.00
IUUC-Mmu-064354 Mus musculus 90.26 0.00e+00 1065.00
IUUC-Mac-065632 Musa acuminata 44.74 2.00e-115 409.00
IUUC-Mpu-066749 Mustela putorius furo 90.67 0.00e+00 1064.00
IUUC-Mlu-067579 Myotis lucifugus 93.62 0.00e+00 1122.00
IUUC-Nfi-068556 Neosartorya fischeri 30.13 2.00e-60 226.00
IUUC-Ncr-068877 Neurospora crassa 31.48 6.00e-62 231.00
IUUC-Nle-069176 Nomascus leucogenys 99.83 0.00e+00 1069.00
IUUC-Opr-070293 Ochotona princeps 88.07 0.00e+00 1052.00
IUUC-Ont-071297 Oreochromis niloticus 68.54 0.00e+00 832.00
IUUC-Oan-073450 Ornithorhynchus anatinus 82.50 3.00e-57 213.00
IUUC-Ocu-074449 Oryctolagus cuniculus 94.51 0.00e+00 1138.00
IUUC-Oba-075858 Oryza barthii 44.47 5.00e-115 408.00
IUUC-Obr-076052 Oryza brachyantha 44.97 2.00e-117 416.00
IUUC-Ogl-077756 Oryza glaberrima 44.97 2.00e-118 419.00
IUUC-Ogu-078993 Oryza glumaepatula 44.47 8.00e-115 408.00
IUUC-Oin-079429 Oryza indica 44.76 1.00e-117 417.00
IUUC-Olo-080823 Oryza longistaminata 45.01 2.00e-114 405.00
IUUC-Ome-081852 Oryza meridionalis 44.97 2.00e-118 419.00
IUUC-Oni-082474 Oryza nivara 44.47 6.00e-115 408.00
IUUC-Opu-083450 Oryza punctata 42.11 4.00e-107 382.00
IUUC-Oru-084642 Oryza rufipogon 44.47 4.00e-115 409.00
IUUC-Osa-086011 Oryza sativa 44.97 1.00e-117 417.00
IUUC-Ola-086398 Oryzias latipes 67.78 0.00e+00 832.00
IUUC-Olu-087769 Ostreococcus lucimarinus 34.76 9.00e-72 264.00
IUUC-Oga-088727 Otolemur garnettii 96.84 0.00e+00 1020.00
IUUC-Oar-090392 Ovis aries 94.50 0.00e+00 1114.00
IUUC-Ptr-090921 Pan troglodytes 99.54 0.00e+00 1173.00
IUUC-Pan-092085 Papio anubis 98.08 0.00e+00 1116.00
IUUC-Psi-093709 Pelodiscus sinensis 76.93 0.00e+00 920.00
IUUC-Pno-095050 Phaeosphaeria nodorum 29.69 2.00e-56 213.00
IUUC-Ppa-095333 Physcomitrella patens 41.26 4.00e-115 409.00
IUUC-Pfo-097401 Poecilia formosa 68.42 0.00e+00 828.00
IUUC-Pab-097766 Pongo abelii 99.69 0.00e+00 1172.00
IUUC-Pop-099011 Populus trichocarpa 41.39 6.00e-116 411.00
IUUC-Pca-100351 Procavia capensis 70.40 7.00e-138 484.00
IUUC-Ppe-101384 Prunus persica 42.83 3.00e-118 419.00
IUUC-Pva-102654 Pteropus vampyrus 92.97 0.00e+00 1113.00
IUUC-Pgr-103415 Puccinia graminis 42.92 1.00e-108 387.00
IUUC-Ptt-103925 Puccinia triticina 43.12 3.00e-109 389.00
IUUC-Pte-104394 Pyrenophora teres 29.70 4.00e-56 212.00
IUUC-Pyt-104674 Pyrenophora triticirepentis 29.39 3.00e-55 209.00
IUUC-Rno-105663 Rattus norvegicus 92.67 0.00e+00 1093.00
IUUC-Sha-107567 Sarcophilus harrisii 76.30 0.00e+00 983.00
IUUC-Sja-107939 Schizosaccharomyces japonicus 29.94 2.00e-53 204.00
IUUC-Spo-108037 Schizosaccharomyces pombe 29.81 1.00e-49 191.00
IUUC-Ssl-108526 Sclerotinia sclerotiorum 30.14 2.00e-58 220.00
IUUC-Smo-108751 Selaginella moellendorffii 42.68 4.00e-115 408.00
IUUC-Sit-110170 Setaria italica 44.42 1.00e-117 416.00
IUUC-Sly-111518 Solanum lycopersicum 42.27 3.00e-104 372.00
IUUC-Stu-112755 Solanum tuberosum 44.95 7.00e-119 421.00
IUUC-Sar-113590 Sorex araneus 78.81 0.00e+00 786.00
IUUC-Sbi-114091 Sorghum bicolor 44.95 7.00e-119 421.00
IUUC-Sre-115111 Sporisorium reilianum 32.29 2.00e-46 180.00
IUUC-Ssc-115453 Sus scrofa 94.11 0.00e+00 997.00
IUUC-Tgu-117285 Taeniopygia guttata 73.81 0.00e+00 874.00
IUUC-Tru-118474 Takifugu rubripes 66.67 0.00e+00 821.00
IUUC-Tsy-119547 Tarsius syrichta 87.92 0.00e+00 980.00
IUUC-Tni-120818 Tetraodon nigroviridis 66.30 0.00e+00 790.00
IUUC-Tca-121621 Theobroma cacao 43.09 3.00e-114 405.00
IUUC-Tre-122146 Trichoderma reesei 32.04 3.00e-68 253.00
IUUC-Tvi-122353 Trichoderma virens 32.16 6.00e-68 251.00
IUUC-Tae-123385 Triticum aestivum 39.32 4.00e-83 302.00
IUUC-Tur-125971 Triticum urartu 43.95 2.00e-114 405.00
IUUC-Tme-127185 Tuber melanosporum 30.17 9.00e-52 198.00
IUUC-Tbe-127554 Tupaia belangeri 69.77 0.00e+00 796.00
IUUC-Ttr-128995 Tursiops truncatus 95.27 0.00e+00 1139.00
IUUC-Uma-129618 Ustilago maydis 30.21 4.00e-48 186.00
IUUC-Vda-129832 Verticillium dahliae 29.18 6.00e-54 205.00
IUUC-Vpa-130592 Vicugna pacos 83.94 0.00e+00 832.00
IUUC-Vvi-131574 Vitis vinifera 44.74 8.00e-118 417.00
IUUC-Xtr-132234 Xenopus tropicalis 76.37 0.00e+00 912.00
IUUC-Xma-133780 Xiphophorus maculatus 66.87 0.00e+00 833.00
IUUC-Yli-134658 Yarrowia lipolytica 35.86 3.00e-15 76.60
IUUC-Zma-135697 Zea mays 44.33 8.00e-116 411.00
Created Date 25-Jun-2017

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