iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	5.10e-24	84.9	14	119

Active Site

Position(s)	Description	Evidence
91	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilk.eeekWspalsves 100
           Rl+ke++el ++p+e ++a+p+++ +l+ew+++i G  +t +egg+++ +i fp dYP+kPP++ +lt+  ++ ++ n kvClsi + ++e+W p +s+++
   Q: 14   RLMKEAMEL-RQPTEMYHAQPMED-NLFEWHFTIRGTLGTDFEGGIYHGRIIFPADYPMKPPNLILLTP--NGRFELNKKVCLSISGyHPETWLPSWSIRT 110
           9*******9.789999********.9*******************************************..999************779************ PP
   S: 101  vllsiqsll 109
            ll+++ +l
   Q: 111  ALLALIGFL 119
           *****9998 PP

Organism

Caenorhabditis elegans

Protein Sequence
(Fasta)

MSEQYNTKNA GVRRLMKEAM ELRQPTEMYH AQPMEDNLFE WHFTIRGTLG TDFEGGIYHG 60
RIIFPADYPM KPPNLILLTP NGRFELNKKV CLSISGYHPE TWLPSWSIRT ALLALIGFLP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGAGTTCTTC GGGTCTCGCT GACGTTGGTT TCGGTTTTCC AGTTTTTTTC TCATTTCCGT 60
CTTCATTTAT TGTCATTTGA CTGAAAGTAC GAGAATTTAG AGAATAAAAT GAGTGAGCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR000608--UBQ-conjugat_E2
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0016021--C:integral component of membrane
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding

KEGG

cel:CELE_D1022.1

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001180	Aegilops tauschii	41.28	5.00e-33	134.00
IUUC-Aml-002404	Ailuropoda melanoleuca	62.23	3.00e-71	260.00
IUUC-Atr-002806	Amborella trichopoda	57.24	1.00e-48	185.00
IUUC-Apl-003507	Anas platyrhynchos	56.76	2.00e-71	261.00
IUUC-Aca-004697	Anolis carolinensis	56.50	8.00e-72	262.00
IUUC-Aly-005556	Arabidopsis lyrata	60.69	6.00e-53	199.00
IUUC-Ath-007477	Arabidopsis thaliana	60.69	5.00e-53	199.00
IUUC-Acl-008101	Aspergillus clavatus	50.69	9.00e-40	155.00
IUUC-Afl-008466	Aspergillus flavus	48.97	9.00e-37	145.00
IUUC-Afu-009109	Aspergillus fumigatus	50.35	2.00e-35	141.00
IUUC-Ani-009343	Aspergillus nidulans	49.66	6.00e-38	150.00
IUUC-Ang-009509	Aspergillus niger	52.03	3.00e-34	135.00
IUUC-Aor-010210	Aspergillus oryzae	48.97	1.00e-36	145.00
IUUC-Ate-010571	Aspergillus terreus	43.75	6.00e-32	131.00
IUUC-Ame-010806	Astyanax mexicanus	66.67	5.00e-68	249.00
IUUC-Bgr-012063	Blumeria graminis	39.74	3.00e-43	167.00
IUUC-Bta-012638	Bos taurus	61.08	3.00e-68	250.00
IUUC-Bci-013709	Botrytis cinerea	39.27	1.00e-46	178.00
IUUC-Bdi-014694	Brachypodium distachyon	55.56	1.00e-48	185.00
IUUC-Bol-016079	Brassica oleracea	60.00	8.00e-53	199.00
IUUC-Bra-017267	Brassica rapa	60.00	6.00e-53	199.00
IUUC-Cja-019087	Callithrix jacchus	61.70	2.00e-70	257.00
IUUC-Cfa-020218	Canis familiaris	61.62	5.00e-69	253.00
IUUC-Cpo-022552	Cavia porcellus	61.70	4.00e-70	256.00
IUUC-Cre-022888	Chlamydomonas reinhardtii	56.34	4.00e-48	182.00
IUUC-Csa-024028	Chlorocebus sabaeus	62.23	5.00e-71	259.00
IUUC-Cho-024606	Choloepus hoffmanni	45.75	2.00e-36	144.00
IUUC-Cin-025631	Ciona intestinalis	52.34	2.00e-63	234.00
IUUC-Csv-026321	Ciona savignyi	56.59	3.00e-59	220.00
IUUC-Cgl-026755	Colletotrichum gloeosporioides	45.11	2.00e-43	167.00
IUUC-Cne-026839	Cryptococcus neoformans	44.23	3.00e-37	147.00
IUUC-Cme-027189	Cyanidioschyzon merolae	52.05	1.00e-38	152.00
IUUC-Dre-027569	Danio rerio	48.99	1.00e-65	241.00
IUUC-Dno-029214	Dasypus novemcinctus	61.70	4.00e-70	256.00
IUUC-Dse-031537	Dothistroma septosporum	52.08	4.00e-43	166.00
IUUC-Ete-033083	Echinops telfairi	62.23	5.00e-71	259.00
IUUC-Eca-034179	Equus caballus	63.28	8.00e-68	249.00
IUUC-Eeu-035115	Erinaceus europaeus	48.94	3.00e-50	190.00
IUUC-Fca-036083	Felis catus	62.23	3.00e-71	260.00
IUUC-Fal-037289	Ficedula albicollis	56.34	4.00e-69	253.00
IUUC-Fox-038027	Fusarium oxysporum	49.11	6.00e-35	139.00
IUUC-Fso-038254	Fusarium solani	49.01	6.00e-44	169.00
IUUC-Ggr-039884	Gaeumannomyces graminis	47.68	2.00e-42	164.00
IUUC-Gga-041156	Gallus gallus	44.89	1.00e-71	261.00
IUUC-Gma-042751	Glycine max	38.73	5.00e-51	193.00
IUUC-Ggo-044450	Gorilla gorilla	61.70	3.00e-70	257.00
IUUC-Hsa-046496	Homo sapiens	61.70	4.00e-70	256.00
IUUC-Hvu-047328	Hordeum vulgare	56.25	2.00e-48	184.00
IUUC-Itr-048629	Ictidomys tridecemlineatus	61.70	2.00e-70	257.00
IUUC-Lch-050348	Latimeria chalumnae	63.49	5.00e-73	266.00
IUUC-Lpe-050862	Leersia perrieri	55.56	1.00e-47	181.00
IUUC-Loc-052465	Lepisosteus oculatus	56.12	6.00e-65	239.00
IUUC-Lma-053257	Leptosphaeria maculans	45.59	2.00e-47	181.00
IUUC-Laf-053830	Loxodonta africana	61.70	3.00e-70	257.00
IUUC-Mcc-054880	Macaca mulatta	62.23	6.00e-71	259.00
IUUC-Mor-057183	Magnaporthe oryzae	46.36	1.00e-41	162.00
IUUC-Mpo-057391	Magnaporthe poae	47.06	3.00e-43	167.00
IUUC-Mtr-058479	Medicago truncatula	56.29	2.00e-50	191.00
IUUC-Mga-059321	Meleagris gallopavo	65.17	3.00e-69	253.00
IUUC-Mvi-060366	Microbotryum violaceum	58.62	3.00e-51	194.00
IUUC-Mmr-061717	Microcebus murinus	63.28	3.00e-68	250.00
IUUC-Mdo-062391	Monodelphis domestica	57.43	4.00e-67	246.00
IUUC-Mmu-064049	Mus musculus	61.70	5.00e-70	256.00
IUUC-Mac-064541	Musa acuminata	56.55	1.00e-48	185.00
IUUC-Mpu-066177	Mustela putorius furo	63.58	1.00e-66	245.00
IUUC-Mlu-067037	Myotis lucifugus	59.28	1.00e-68	251.00
IUUC-Nfi-068283	Neosartorya fischeri	50.35	1.00e-38	152.00
IUUC-Ncr-068645	Neurospora crassa	48.34	9.00e-45	172.00
IUUC-Nle-069166	Nomascus leucogenys	62.23	2.00e-71	260.00
IUUC-Ont-072096	Oreochromis niloticus	62.84	2.00e-69	254.00
IUUC-Oan-073369	Ornithorhynchus anatinus	64.41	9.00e-69	252.00
IUUC-Ocu-074815	Oryctolagus cuniculus	59.61	3.00e-70	256.00
IUUC-Oba-075649	Oryza barthii	55.56	2.00e-47	181.00
IUUC-Obr-076169	Oryza brachyantha	56.25	3.00e-48	184.00
IUUC-Ogl-077144	Oryza glaberrima	55.56	2.00e-47	181.00
IUUC-Ogu-078255	Oryza glumaepatula	55.56	2.00e-47	181.00
IUUC-Oin-079510	Oryza indica	56.25	2.00e-46	177.00
IUUC-Olo-080589	Oryza longistaminata	42.78	6.00e-41	159.00
IUUC-Ome-081849	Oryza meridionalis	50.96	1.00e-44	171.00
IUUC-Oni-082959	Oryza nivara	55.56	2.00e-47	181.00
IUUC-Opu-083736	Oryza punctata	55.56	5.00e-47	180.00
IUUC-Oru-084215	Oryza rufipogon	55.56	2.00e-47	181.00
IUUC-Osa-085722	Oryza sativa	55.56	2.00e-47	181.00
IUUC-Ola-086717	Oryzias latipes	62.09	3.00e-69	253.00
IUUC-Olu-087750	Ostreococcus lucimarinus	55.96	9.00e-34	133.00
IUUC-Oga-088848	Otolemur garnettii	69.01	2.00e-61	227.00
IUUC-Oar-090134	Ovis aries	62.57	1.00e-67	248.00
IUUC-Ptr-091314	Pan troglodytes	61.70	3.00e-70	257.00
IUUC-Pan-092103	Papio anubis	62.23	5.00e-71	259.00
IUUC-Psi-093668	Pelodiscus sinensis	63.01	7.00e-66	242.00
IUUC-Pno-094982	Phaeosphaeria nodorum	51.75	1.00e-42	165.00
IUUC-Ppa-095836	Physcomitrella patens	54.38	7.00e-51	192.00
IUUC-Pfo-096964	Poecilia formosa	57.67	1.00e-73	268.00
IUUC-Pab-097857	Pongo abelii	61.70	3.00e-70	257.00
IUUC-Pop-099840	Populus trichocarpa	58.62	1.00e-49	188.00
IUUC-Pca-101108	Procavia capensis	59.26	2.00e-33	134.00
IUUC-Ppe-101444	Prunus persica	56.43	3.00e-48	184.00
IUUC-Pva-102297	Pteropus vampyrus	48.13	2.00e-51	194.00
IUUC-Pte-104112	Pyrenophora teres	52.63	7.00e-48	182.00
IUUC-Pyt-104824	Pyrenophora triticirepentis	53.60	2.00e-40	157.00
IUUC-Rno-105336	Rattus norvegicus	61.70	2.00e-69	253.00
IUUC-Sha-107324	Sarcophilus harrisii	62.23	3.00e-71	260.00
IUUC-Smo-109196	Selaginella moellendorffii	58.16	2.00e-49	187.00
IUUC-Sit-110794	Setaria italica	56.94	5.00e-49	186.00
IUUC-Sly-111585	Solanum lycopersicum	57.14	5.00e-49	186.00
IUUC-Stu-111996	Solanum tuberosum	57.14	7.00e-49	186.00
IUUC-Sar-113063	Sorex araneus	63.84	1.00e-68	251.00
IUUC-Sbi-114593	Sorghum bicolor	56.94	5.00e-49	186.00
IUUC-Sre-115043	Sporisorium reilianum	55.63	1.00e-50	191.00
IUUC-Ssc-115523	Sus scrofa	62.23	3.00e-70	256.00
IUUC-Tgu-116966	Taeniopygia guttata	61.69	7.00e-72	262.00
IUUC-Tru-117737	Takifugu rubripes	60.00	1.00e-69	254.00
IUUC-Tsy-119190	Tarsius syrichta	71.96	4.00e-46	176.00
IUUC-Tni-120283	Tetraodon nigroviridis	70.27	2.00e-32	128.00
IUUC-Tca-120992	Theobroma cacao	46.73	1.00e-49	188.00
IUUC-Tre-122028	Trichoderma reesei	50.00	8.00e-42	162.00
IUUC-Tvi-122637	Trichoderma virens	40.27	2.00e-44	171.00
IUUC-Tae-124782	Triticum aestivum	56.25	1.00e-48	185.00
IUUC-Tme-126962	Tuber melanosporum	48.70	4.00e-47	180.00
IUUC-Tbe-127743	Tupaia belangeri	63.28	9.00e-68	248.00
IUUC-Ttr-129193	Tursiops truncatus	63.28	2.00e-67	247.00
IUUC-Uma-129586	Ustilago maydis	43.58	1.00e-50	191.00
IUUC-Vda-129959	Verticillium dahliae	50.33	2.00e-44	171.00
IUUC-Vpa-130404	Vicugna pacos	63.28	9.00e-68	248.00
IUUC-Vvi-130893	Vitis vinifera	38.33	3.00e-51	193.00
IUUC-Xtr-131832	Xenopus tropicalis	62.92	3.00e-67	246.00
IUUC-Zma-135443	Zea mays	57.64	4.00e-50	190.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence