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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Cel-018656
Ensembl Protein ID F35G12.4c
UniProt Accession Q20059; B3GWA7; Q9U3G8; WDR48_CAEEL
Genbank Protein ID CAA86335.2; CAA86338.2; CAQ58416.1
Protein Name WD repeat-containing protein 48 homolog
Genbank Nucleotide ID Z46242; Z46242; Z46242
Gene Name wdr-48; F35G12.4
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
WBGene00009441 F35G12.4a F35G12.4a
WBGene00009441 F35G12.4b F35G12.4b
WBGene00009441 F35G12.4c F35G12.4c
Annotation
mRNA Expression
GEO
DNA & RNA Element
microRNARAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 2.60e-22 78.3 218 255
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           gHtd v++l   +d t+ +s++ D ti++WD+ +++++
   Q: 218  GHTDNVRALVVnDDgTRALSAGSDATIRLWDIGQQRCI 255
           8********778779****************9999987 PP
   
Organism Caenorhabditis elegans
Functional Description
(View)

Functional Description


     Together with wdr-20, binds to and stimulates the activity of the deubiquitinating enzyme usp-46, leading to deubiquitination and stabilization of the glr-1 glutamate receptor.
 Together with wdr-20, binds to and stimulates the activity of the deubiquitinating enzyme usp-46, leading to deubiquitination and stabilization of the glr-1 glutamate receptor.
Protein Sequence
(Fasta)
MSSCVNTSQT GPKKKISFII RDEHEYSNRS AVSALQYDAQ NGRLFTGGSD TIIRTWSVPH 60
HKDAFSARGG VRSPGKNSPV QYQGSLEQHT DWVNDMILCG HGKILISASN DTTVKVWNIE 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Cel-018656|E3,WD_repeat|Caenorhabditis elegans
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATCTCAAAAG GCGTTCAATG CAATAAAATG AGTAGCTGTG TAAATACCAG TCAAACTGGT 60
CCAAAAAAGA AAATCTCATT TATCATTCGC GATGAGCACG AGTATTCAAA TCGTTCGGCT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Cel-018656|E3,WD_repeat|Caenorhabditis elegans
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0833--Ubl conjugation pathway
KW-0853--WD repeat
Interpro

IPR021772--DUF3337
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF11816--DUF3337
PF00400--WD40
PRINTS

PR00320--GPROTEINBRPT
SMART

SM00320--WD40
Gene Ontology

GO:0010628--P:positive regulation of gene expression
GO:0090326--P:positive regulation of locomotion involved in locomotory behavior
GO:1903003--P:positive regulation of protein deubiquitination
GO:2000010--P:positive regulation of protein localization to cell surface
KEGG cel:CELE_F35G12.4
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-001160 Aegilops tauschii 29.55 3.00e-64 238.00
IUUC-Aml-001533 Ailuropoda melanoleuca 43.58 4.00e-151 526.00
IUUC-Atr-003009 Amborella trichopoda 28.46 5.00e-82 297.00
IUUC-Apl-003709 Anas platyrhynchos 46.84 2.00e-80 291.00
IUUC-Aca-004875 Anolis carolinensis 44.01 3.00e-153 534.00
IUUC-Aly-005464 Arabidopsis lyrata 28.59 4.00e-79 288.00
IUUC-Ath-006969 Arabidopsis thaliana 29.40 2.00e-81 295.00
IUUC-Acl-008203 Aspergillus clavatus 26.90 9.00e-51 194.00
IUUC-Afl-008571 Aspergillus flavus 28.88 2.00e-37 149.00
IUUC-Afu-009072 Aspergillus fumigatus 28.35 3.00e-34 139.00
IUUC-Ani-009413 Aspergillus nidulans 26.37 3.00e-47 182.00
IUUC-Ang-009571 Aspergillus niger 26.70 5.00e-47 181.00
IUUC-Aor-010064 Aspergillus oryzae 28.88 1.00e-37 150.00
IUUC-Ate-010463 Aspergillus terreus 26.93 4.00e-48 185.00
IUUC-Ame-010875 Astyanax mexicanus 42.15 2.00e-133 468.00
IUUC-Bgr-012288 Blumeria graminis 29.84 3.00e-51 196.00
IUUC-Bta-013379 Bos taurus 43.72 1.00e-151 528.00
IUUC-Bci-013859 Botrytis cinerea 30.14 2.00e-37 149.00
IUUC-Bdi-014645 Brachypodium distachyon 29.03 3.00e-82 298.00
IUUC-Bol-016450 Brassica oleracea 30.51 2.00e-80 292.00
IUUC-Bra-017237 Brassica rapa 29.27 2.00e-81 295.00
IUUC-Cja-018804 Callithrix jacchus 43.72 2.00e-151 528.00
IUUC-Cfa-020076 Canis familiaris 43.72 2.00e-151 527.00
IUUC-Cpo-021721 Cavia porcellus 43.77 8.00e-151 526.00
IUUC-Cre-022779 Chlamydomonas reinhardtii 33.63 1.00e-43 171.00
IUUC-Csa-023188 Chlorocebus sabaeus 43.72 2.00e-151 527.00
IUUC-Cho-024932 Choloepus hoffmanni 43.62 1.00e-148 518.00
IUUC-Cin-025591 Ciona intestinalis 38.76 4.00e-136 477.00
IUUC-Cgl-026540 Colletotrichum gloeosporioides 26.79 8.00e-20 91.30
IUUC-Cne-026819 Cryptococcus neoformans 30.43 9.00e-26 111.00
IUUC-Cme-027188 Cyanidioschyzon merolae 28.03 2.00e-55 209.00
IUUC-Dre-028370 Danio rerio 42.25 6.00e-152 530.00
IUUC-Dno-029960 Dasypus novemcinctus 44.01 8.00e-151 526.00
IUUC-Dor-030933 Dipodomys ordii 41.77 5.00e-75 273.00
IUUC-Dse-031532 Dothistroma septosporum 28.61 5.00e-34 138.00
IUUC-Dme-032168 Drosophila melanogaster 38.79 1.00e-129 455.00
IUUC-Ete-033107 Echinops telfairi 42.78 4.00e-144 503.00
IUUC-Eca-034028 Equus caballus 43.86 8.00e-152 529.00
IUUC-Eeu-034894 Erinaceus europaeus 42.29 4.00e-99 354.00
IUUC-Fca-035619 Felis catus 42.91 2.00e-107 381.00
IUUC-Fal-036869 Ficedula albicollis 43.88 7.00e-153 533.00
IUUC-Fox-037907 Fusarium oxysporum 27.35 2.00e-50 193.00
IUUC-Fso-038101 Fusarium solani 26.89 4.00e-46 179.00
IUUC-Gmo-038627 Gadus morhua 43.44 8.00e-153 532.00
IUUC-Ggr-039995 Gaeumannomyces graminis 29.01 1.00e-37 150.00
IUUC-Gga-040555 Gallus gallus 43.80 3.00e-152 530.00
IUUC-Gac-042497 Gasterosteus aculeatus 43.72 8.00e-153 532.00
IUUC-Gma-043327 Glycine max 28.50 2.00e-77 282.00
IUUC-Ggo-045561 Gorilla gorilla 43.72 2.00e-151 527.00
IUUC-Hsa-045710 Homo sapiens 43.72 2.00e-151 527.00
IUUC-Hvu-047730 Hordeum vulgare 30.60 5.00e-65 240.00
IUUC-Itr-049030 Ictidomys tridecemlineatus 43.09 2.00e-104 371.00
IUUC-Kpa-049237 Komagataella pastoris 31.55 7.00e-22 98.20
IUUC-Lch-049507 Latimeria chalumnae 43.53 2.00e-152 531.00
IUUC-Lpe-051608 Leersia perrieri 29.47 9.00e-82 296.00
IUUC-Loc-052373 Lepisosteus oculatus 42.28 2.00e-144 504.00
IUUC-Lma-053025 Leptosphaeria maculans 30.90 4.00e-40 159.00
IUUC-Laf-053706 Loxodonta africana 43.42 5.00e-150 523.00
IUUC-Mcc-055046 Macaca mulatta 43.72 2.00e-151 527.00
IUUC-Meu-056840 Macropus eugenii 32.48 5.00e-41 161.00
IUUC-Mor-057284 Magnaporthe oryzae 28.92 1.00e-40 160.00
IUUC-Mpo-057418 Magnaporthe poae 29.38 5.00e-38 152.00
IUUC-Mtr-058571 Medicago truncatula 28.68 9.00e-86 310.00
IUUC-Mla-059101 Melampsora laricipopulina 41.43 4.00e-43 169.00
IUUC-Mga-059297 Meleagris gallopavo 43.80 3.00e-152 530.00
IUUC-Mvi-060419 Microbotryum violaceum 35.61 6.00e-33 135.00
IUUC-Mmr-061196 Microcebus murinus 42.57 3.00e-142 497.00
IUUC-Mdo-062762 Monodelphis domestica 42.72 8.00e-150 522.00
IUUC-Mmu-063915 Mus musculus 43.95 4.00e-152 530.00
IUUC-Mac-065434 Musa acuminata 27.81 2.00e-75 276.00
IUUC-Mpu-065999 Mustela putorius furo 43.33 7.00e-98 349.00
IUUC-Mlu-068226 Myotis lucifugus 43.72 1.00e-151 528.00
IUUC-Nfi-068416 Neosartorya fischeri 26.83 2.00e-49 189.00
IUUC-Ncr-068825 Neurospora crassa 26.40 1.00e-46 180.00
IUUC-Nle-069416 Nomascus leucogenys 43.72 2.00e-151 527.00
IUUC-Opr-070515 Ochotona princeps 42.31 9.00e-144 502.00
IUUC-Ont-072052 Oreochromis niloticus 42.56 8.00e-145 506.00
IUUC-Oan-073636 Ornithorhynchus anatinus 43.80 3.00e-152 531.00
IUUC-Ocu-074799 Oryctolagus cuniculus 43.58 4.00e-151 527.00
IUUC-Oba-075146 Oryza barthii 29.28 1.00e-81 296.00
IUUC-Obr-076699 Oryza brachyantha 29.13 7.00e-83 300.00
IUUC-Ogl-077883 Oryza glaberrima 30.60 2.00e-53 201.00
IUUC-Ogu-078114 Oryza glumaepatula 27.93 8.00e-75 273.00
IUUC-Oin-079575 Oryza indica 29.58 2.00e-86 312.00
IUUC-Olo-080531 Oryza longistaminata 28.40 6.00e-77 280.00
IUUC-Ome-081368 Oryza meridionalis 27.53 6.00e-70 257.00
IUUC-Oni-082457 Oryza nivara 29.11 9.00e-82 296.00
IUUC-Opu-084050 Oryza punctata 28.85 1.00e-81 296.00
IUUC-Oru-084330 Oryza rufipogon 29.28 1.00e-81 296.00
IUUC-Osa-085408 Oryza sativa 29.58 2.00e-86 312.00
IUUC-Ola-087546 Oryzias latipes 43.29 5.00e-152 530.00
IUUC-Olu-087710 Ostreococcus lucimarinus 28.51 3.00e-63 234.00
IUUC-Oga-087998 Otolemur garnettii 43.85 1.00e-151 528.00
IUUC-Oar-090303 Ovis aries 43.72 1.00e-151 528.00
IUUC-Ptr-090588 Pan troglodytes 43.72 2.00e-151 527.00
IUUC-Pan-092722 Papio anubis 43.72 2.00e-151 527.00
IUUC-Psi-093911 Pelodiscus sinensis 43.70 3.00e-152 530.00
IUUC-Pma-094580 Petromyzon marinus 43.18 3.00e-150 524.00
IUUC-Pno-095085 Phaeosphaeria nodorum 26.96 3.00e-48 186.00
IUUC-Ppa-095594 Physcomitrella patens 28.88 4.00e-77 281.00
IUUC-Pfo-096994 Poecilia formosa 43.41 2.00e-150 525.00
IUUC-Pab-097586 Pongo abelii 43.72 7.00e-151 526.00
IUUC-Pop-099389 Populus trichocarpa 28.12 2.00e-79 288.00
IUUC-Pca-100458 Procavia capensis 46.93 1.00e-49 189.00
IUUC-Ppe-102060 Prunus persica 28.70 2.00e-81 295.00
IUUC-Pva-102698 Pteropus vampyrus 42.17 2.00e-148 518.00
IUUC-Pgr-103649 Puccinia graminis 36.40 8.00e-45 174.00
IUUC-Ptt-103910 Puccinia triticina 34.50 8.00e-46 177.00
IUUC-Pte-104181 Pyrenophora teres 31.50 1.00e-40 160.00
IUUC-Pyt-104439 Pyrenophora triticirepentis 30.89 2.00e-40 160.00
IUUC-Rno-104978 Rattus norvegicus 44.00 1.00e-151 528.00
IUUC-Sha-107079 Sarcophilus harrisii 44.69 7.00e-142 496.00
IUUC-Sja-107716 Schizosaccharomyces japonicus 27.88 2.00e-50 193.00
IUUC-Spo-108325 Schizosaccharomyces pombe 27.94 1.00e-43 170.00
IUUC-Ssl-108542 Sclerotinia sclerotiorum 25.83 4.00e-47 182.00
IUUC-Smo-109427 Selaginella moellendorffii 30.01 2.00e-86 312.00
IUUC-Sit-110755 Setaria italica 28.52 4.00e-82 297.00
IUUC-Sly-111099 Solanum lycopersicum 29.28 5.00e-73 267.00
IUUC-Sar-113408 Sorex araneus 43.44 1.00e-87 315.00
IUUC-Sbi-113789 Sorghum bicolor 29.80 8.00e-82 296.00
IUUC-Sre-114998 Sporisorium reilianum 39.52 5.00e-40 159.00
IUUC-Ssc-115434 Sus scrofa 43.72 2.00e-151 527.00
IUUC-Tgu-116517 Taeniopygia guttata 44.01 6.00e-153 533.00
IUUC-Tru-118174 Takifugu rubripes 43.31 9.00e-153 532.00
IUUC-Tsy-118935 Tarsius syrichta 43.64 7.00e-151 526.00
IUUC-Tni-119744 Tetraodon nigroviridis 43.72 2.00e-152 531.00
IUUC-Tca-121360 Theobroma cacao 27.42 1.00e-75 276.00
IUUC-Tre-122198 Trichoderma reesei 30.50 4.00e-41 162.00
IUUC-Tvi-122389 Trichoderma virens 30.77 7.00e-43 167.00
IUUC-Tae-125576 Triticum aestivum 28.31 2.00e-82 298.00
IUUC-Tur-126699 Triticum urartu 27.85 1.00e-79 290.00
IUUC-Tme-126932 Tuber melanosporum 26.40 3.00e-42 166.00
IUUC-Tbe-127267 Tupaia belangeri 36.23 2.00e-75 275.00
IUUC-Ttr-129153 Tursiops truncatus 43.86 1.00e-152 531.00
IUUC-Uma-129604 Ustilago maydis 39.05 8.00e-40 158.00
IUUC-Vda-129925 Verticillium dahliae 30.56 2.00e-43 169.00
IUUC-Vpa-130553 Vicugna pacos 42.27 3.00e-108 384.00
IUUC-Vvi-130995 Vitis vinifera 27.66 9.00e-78 283.00
IUUC-Xtr-132346 Xenopus tropicalis 43.52 3.00e-151 527.00
IUUC-Xma-133654 Xiphophorus maculatus 48.53 1.00e-74 271.00
IUUC-Yli-134451 Yarrowia lipolytica 25.73 1.00e-40 160.00
IUUC-Zma-135647 Zea mays 29.46 7.00e-84 303.00
Created Date 25-Jun-2017

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