iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	TRANSFAC	RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/DCUN1	5.20e-83	278.1	47	232

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/DCUN1

   S: 2    skkkleelferYkdpqedligieglekfcedlgvdpediavLvlawkleaatlcefsreefldgltalgcdsieklqeklktleselkd 90
           s+kk+ ++f++Y++p+e ++g eg+ekfced+gv+pe+i++Lvlawklea+++++f++ee+l+g+t+l+cd++eklq ++++l+s+l+d
   Q: 47   SRKKCLAWFYEYAGPDE-VVGPEGMEKFCEDIGVEPENIIMLVLAWKLEAESMGFFTKEEWLKGMTSLQCDCTEKLQSRFDFLRSQLND 134
           78*************95.*********************************************************************** PP
   S: 91   eqkfkdiYrfafnfakdkgqksldldtaialwkLllaerefklldawlkfLeeekkksiskDtWnllLefskviakdlsnYdeegaWPv 179
           +++fk+iYr+af+fa+dk+q+sld+dta+++++Lll +r+++l+++++++Le++k+++++kD+W+++Lefs+++++dlsnYde+gaWPv
   Q: 135  ISSFKNIYRYAFDFARDKDQRSLDIDTAKSMLALLL-GRTWPLFSVFYQYLEQSKYRVMNKDQWYNVLEFSRTVHADLSNYDEDGAWPV 222
           ************************************.999************************************************* PP
   S: 180  liDefveylk 189
           l+Defve++k
   Q: 223  LLDEFVEWQK 232
           ********86 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MPVKKKRKAP GVAAAVAEDA GLKKCKISSY CRSQPPARLI SGEEDFSRKK CLAWFYEYAG 60
PDEVVGPEGM EKFCEDIGVE PENIIMLVLA WKLEAESMGF FTKEEWLKGM TSLQCDCTEK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGACTACTGA AGGTGCCGCG CTGTCGGCGT TCGCTTCCCC TGGAAAAGCC CGAGCCGCGT 60
TATCGCCGGG CTTAGCGCTG CGCTGCCCCG AATCGCCCCT AAAGAGGAAA CCCGAGGCGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0597--Phosphoprotein
KW-1185--Reference proteome

Interpro

IPR014764--DCN-prot
IPR005176--PONY_dom

PROSITE

PS51229--DCUN1

Pfam

PF03556--Cullin_binding

Gene Ontology

GO:0000151--C:ubiquitin ligase complex
GO:0097602--F:cullin family protein binding
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0032182--F:ubiquitin-like protein binding
GO:0051443--P:positive regulation of ubiquitin-protein transferase activity
GO:0045116--P:protein neddylation

KEGG

rno:315405

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001567	Ailuropoda melanoleuca	97.47	1.00e-137	481.00
IUUC-Apl-003338	Anas platyrhynchos	86.08	1.00e-121	428.00
IUUC-Aca-004660	Anolis carolinensis	89.87	1.00e-127	448.00
IUUC-Afu-009005	Aspergillus fumigatus	31.07	3.00e-17	81.30
IUUC-Bta-013463	Bos taurus	95.36	6.00e-134	469.00
IUUC-Cja-019665	Callithrix jacchus	97.05	1.00e-137	481.00
IUUC-Cfa-020873	Canis familiaris	96.62	8.00e-137	479.00
IUUC-Csa-023661	Chlorocebus sabaeus	97.05	1.00e-137	481.00
IUUC-Cin-025635	Ciona intestinalis	56.10	6.00e-52	196.00
IUUC-Csv-025976	Ciona savignyi	55.96	2.00e-62	232.00
IUUC-Cme-027199	Cyanidioschyzon merolae	23.31	1.00e-07	50.80
IUUC-Dre-028080	Danio rerio	77.02	6.00e-110	389.00
IUUC-Dno-029984	Dasypus novemcinctus	95.40	9.00e-135	473.00
IUUC-Dor-030556	Dipodomys ordii	96.20	6.00e-136	476.00
IUUC-Eca-034108	Equus caballus	97.05	1.00e-137	481.00
IUUC-Fca-035374	Felis catus	89.83	4.00e-122	430.00
IUUC-Fal-037284	Ficedula albicollis	92.96	4.00e-118	416.00
IUUC-Gga-040330	Gallus gallus	91.14	1.00e-128	451.00
IUUC-Gac-042443	Gasterosteus aculeatus	75.64	3.00e-101	360.00
IUUC-Ggo-044892	Gorilla gorilla	97.05	1.00e-137	481.00
IUUC-Hsa-046320	Homo sapiens	97.05	1.00e-137	481.00
IUUC-Itr-048437	Ictidomys tridecemlineatus	97.66	2.00e-72	263.00
IUUC-Lch-049750	Latimeria chalumnae	86.50	1.00e-121	428.00
IUUC-Loc-052941	Lepisosteus oculatus	82.70	5.00e-117	413.00
IUUC-Laf-054402	Loxodonta africana	96.20	1.00e-136	478.00
IUUC-Mcc-055269	Macaca mulatta	97.05	1.00e-137	481.00
IUUC-Meu-056847	Macropus eugenii	83.56	2.00e-105	374.00
IUUC-Mga-059420	Meleagris gallopavo	92.92	1.00e-116	411.00
IUUC-Mmr-061732	Microcebus murinus	96.62	3.00e-137	480.00
IUUC-Mdo-062269	Monodelphis domestica	95.36	2.00e-126	444.00
IUUC-Mmu-063396	Mus musculus	99.53	1.00e-125	442.00
IUUC-Mpu-066206	Mustela putorius furo	98.81	3.00e-97	347.00
IUUC-Mlu-067871	Myotis lucifugus	96.20	4.00e-136	476.00
IUUC-Nfi-068610	Neosartorya fischeri	31.64	5.00e-18	84.00
IUUC-Nle-069808	Nomascus leucogenys	97.05	1.00e-137	481.00
IUUC-Opr-070404	Ochotona princeps	94.69	3.00e-60	224.00
IUUC-Ont-072416	Oreochromis niloticus	71.37	1.00e-95	342.00
IUUC-Oan-072930	Ornithorhynchus anatinus	87.18	8.00e-119	419.00
IUUC-Ocu-073767	Oryctolagus cuniculus	96.20	9.00e-137	478.00
IUUC-Ola-086378	Oryzias latipes	69.33	4.00e-95	340.00
IUUC-Oga-088583	Otolemur garnettii	97.05	1.00e-137	481.00
IUUC-Oar-089612	Ovis aries	96.65	9.00e-121	425.00
IUUC-Ptr-090753	Pan troglodytes	97.05	1.00e-137	481.00
IUUC-Pan-091951	Papio anubis	97.05	1.00e-137	481.00
IUUC-Psi-093385	Pelodiscus sinensis	92.73	8.00e-123	432.00
IUUC-Pma-094582	Petromyzon marinus	71.31	5.00e-99	353.00
IUUC-Pfo-096222	Poecilia formosa	70.66	3.00e-96	344.00
IUUC-Pab-097692	Pongo abelii	97.05	1.00e-137	481.00
IUUC-Pva-102620	Pteropus vampyrus	96.35	2.00e-125	440.00
IUUC-Sha-107177	Sarcophilus harrisii	95.36	2.00e-126	444.00
IUUC-Sar-113656	Sorex araneus	85.58	3.00e-101	360.00
IUUC-Ssc-116272	Sus scrofa	96.20	3.00e-136	476.00
IUUC-Tgu-116631	Taeniopygia guttata	90.87	1.00e-116	411.00
IUUC-Tsy-119350	Tarsius syrichta	96.20	1.00e-136	478.00
IUUC-Tbe-127515	Tupaia belangeri	90.25	1.00e-124	438.00
IUUC-Ttr-128784	Tursiops truncatus	73.00	1.00e-92	332.00
IUUC-Vpa-130543	Vicugna pacos	96.62	2.00e-137	481.00
IUUC-Xtr-132448	Xenopus tropicalis	86.44	3.00e-123	433.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence