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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Sce-106209
Ensembl Protein ID YHL002W
UniProt Accession P38753; D3DKR2; HSE1_YEAST
Genbank Protein ID AAB68427.1; DAA06685.1
Protein Name Class E vacuolar protein-sorting machinery protein HSE1
Genbank Nucleotide ID U10555; BK006934
Gene Name HSE1; YHL002W
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
YHL002W YHL002W YHL002W
Annotation
mRNA Expression
GEOFFGED
Protein-protein Interaction
IIDiRefIndexHINTMentha
Protein 3D Structure
PDBMMDB
Post-translational Modifications (PTMs)
CPLMdbPAFdbPTMUniProt
PHOSIDABioGRID
Protein Expression/Proteomics
GPMDB
Status Reviewed
Details
Family Domain References (PMIDs)
UBD/Alpha-Helix/UIM UIM 17543868
Classification
Family E-value Score Start End
UBD/SH3 7.20e-14 50.0 220 274
UBD/Alpha-Helix/UIM 0.00015 20.0 162 180
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/SH3
   S: 4    ekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekl 62
           ++v++lyd + ++ deL+++kGdv++v+  e+   +W+kg   l+g  G+fP n+v+ +
   Q: 220  RRVRALYDLTTNEPDELSFRKGDVITVL--EQVYRDWWKG--ALRGNMGIFPLNYVTPI 274
           689*************************..99999*****..9*************987 PP
   

   UBD/Alpha-Helix/UIM
   S: 1    dEdeeLqlAlalSlqEeee 19
           ++deeLq+Al +Sl E+e+
   Q: 162  SDDEELQKALKMSLFEYEK 180
           79**************996 PP
   
Organism Saccharomyces cerevisiae
Functional Description
(View)

Functional Description


     Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane.
 Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane.
Protein Sequence
(Fasta)
MSSSAIKIRN ALLKATDPKL RSDNWQYILD VCDLVKEDPE DNGQEVMSLI EKRLEQQDAN 60
VILRTLSLTV SLAENCGSRL RQEISSKNFT SLLYALIESH SVHITLKKAV TDVVKQLSDS 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Sce-106209|UBD,UIM;UBD,SH3|Saccharomyces cerevisiae
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGTCATCAT CTGCGATTAA AATAAGGAAT GCACTGTTGA AGGCAACAGA TCCCAAGTTG 60
AGAAGTGATA ACTGGCAATA CATTTTAGAT GTTTGCGATT TGGTGAAGGA AGATCCCGAA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Sce-106209|UBD,UIM;UBD,SH3|Saccharomyces cerevisiae
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0002--3D-structure
KW-0007--Acetylation
KW-0181--Complete proteome
KW-0967--Endosome
KW-0472--Membrane
KW-0597--Phosphoprotein
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0813--Transport
Interpro

IPR008942--ENTH_VHS
IPR001452--SH3_domain
IPR003903--UIM_dom
IPR002014--VHS_dom
PROSITE

PS50002--SH3
PS50330--UIM
PS50179--VHS
Pfam

PF00018--SH3_1
PF00790--VHS
PRINTS

PR00452--SH3DOMAIN
SMART

SM00326--SH3
SM00726--UIM
SM00288--VHS
Gene Ontology

GO:0005768--C:endosome
GO:0010008--C:endosome membrane
GO:0033565--C:ESCRT-0 complex
GO:0043130--F:ubiquitin binding
GO:1904669--P:ATP export
GO:0045324--P:late endosome to vacuole transport
GO:0006623--P:protein targeting to vacuole
KEGG sce:YHL002W
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002079 Ailuropoda melanoleuca 28.03 1.00e-28 119.00
IUUC-Apl-003548 Anas platyrhynchos 28.14 1.00e-27 115.00
IUUC-Aca-004991 Anolis carolinensis 27.38 2.00e-25 108.00
IUUC-Ago-007874 Ashbya gossypii 46.22 2.00e-101 360.00
IUUC-Acl-008046 Aspergillus clavatus 37.33 3.00e-56 211.00
IUUC-Afl-008621 Aspergillus flavus 35.52 9.00e-62 229.00
IUUC-Afu-008826 Aspergillus fumigatus 36.14 8.00e-54 202.00
IUUC-Ani-009419 Aspergillus nidulans 36.71 6.00e-59 219.00
IUUC-Ang-009580 Aspergillus niger 36.12 8.00e-59 219.00
IUUC-Ate-010532 Aspergillus terreus 34.96 2.00e-57 214.00
IUUC-Ame-011220 Astyanax mexicanus 25.56 2.00e-24 105.00
IUUC-Bgr-012113 Blumeria graminis 33.70 1.00e-57 216.00
IUUC-Bta-013368 Bos taurus 27.11 2.00e-25 108.00
IUUC-Bci-013955 Botrytis cinerea 35.00 8.00e-54 202.00
IUUC-Cel-018461 Caenorhabditis elegans 28.46 2.00e-22 97.80
IUUC-Cja-018846 Callithrix jacchus 26.57 2.00e-28 118.00
IUUC-Cfa-020589 Canis familiaris 28.03 9.00e-29 119.00
IUUC-Cpo-021460 Cavia porcellus 28.03 2.00e-29 121.00
IUUC-Csa-023912 Chlorocebus sabaeus 27.38 4.00e-28 117.00
IUUC-Cho-024297 Choloepus hoffmanni 27.76 3.00e-26 111.00
IUUC-Cin-025272 Ciona intestinalis 49.09 1.00e-12 66.20
IUUC-Cgl-026648 Colletotrichum gloeosporioides 35.81 3.00e-56 210.00
IUUC-Cne-027007 Cryptococcus neoformans 35.92 2.00e-22 99.00
IUUC-Dre-028379 Danio rerio 25.72 7.00e-25 106.00
IUUC-Dno-029182 Dasypus novemcinctus 28.03 7.00e-28 116.00
IUUC-Dor-030515 Dipodomys ordii 25.41 2.00e-20 91.30
IUUC-Dse-031527 Dothistroma septosporum 37.85 4.00e-63 233.00
IUUC-Dme-031987 Drosophila melanogaster 27.08 2.00e-23 101.00
IUUC-Ete-032804 Echinops telfairi 27.84 1.00e-25 108.00
IUUC-Eca-033544 Equus caballus 27.02 1.00e-25 108.00
IUUC-Fca-035958 Felis catus 27.38 5.00e-28 116.00
IUUC-Fal-037355 Ficedula albicollis 26.79 3.00e-24 104.00
IUUC-Fox-037748 Fusarium oxysporum 37.54 4.00e-51 193.00
IUUC-Fso-038126 Fusarium solani 35.31 2.00e-59 221.00
IUUC-Gmo-039628 Gadus morhua 22.60 9.00e-23 99.40
IUUC-Ggr-040048 Gaeumannomyces graminis 35.13 2.00e-59 221.00
IUUC-Gga-041158 Gallus gallus 27.00 3.00e-27 114.00
IUUC-Gac-042301 Gasterosteus aculeatus 24.62 2.00e-24 105.00
IUUC-Gma-044153 Glycine max 31.43 6.00e-06 43.10
IUUC-Ggo-044963 Gorilla gorilla 26.74 8.00e-25 106.00
IUUC-Hsa-046959 Homo sapiens 27.65 4.00e-28 117.00
IUUC-Itr-048399 Ictidomys tridecemlineatus 27.07 9.00e-26 108.00
IUUC-Kpa-049200 Komagataella pastoris 38.90 4.00e-75 273.00
IUUC-Lch-050505 Latimeria chalumnae 27.92 2.00e-26 111.00
IUUC-Loc-052761 Lepisosteus oculatus 26.09 5.00e-24 103.00
IUUC-Lma-053287 Leptosphaeria maculans 39.39 6.00e-61 226.00
IUUC-Laf-053662 Loxodonta africana 27.84 2.00e-25 108.00
IUUC-Mcc-055609 Macaca mulatta 27.38 4.00e-28 117.00
IUUC-Meu-056575 Macropus eugenii 30.83 2.00e-14 71.60
IUUC-Mor-056972 Magnaporthe oryzae 33.59 1.00e-55 209.00
IUUC-Mpo-057476 Magnaporthe poae 35.29 1.00e-59 222.00
IUUC-Mla-059162 Melampsora laricipopulina 36.02 8.00e-28 116.00
IUUC-Mga-059462 Meleagris gallopavo 28.14 5.00e-26 110.00
IUUC-Mvi-060560 Microbotryum violaceum 32.39 2.00e-18 85.90
IUUC-Mmr-061413 Microcebus murinus 26.74 9.00e-25 106.00
IUUC-Mdo-062314 Monodelphis domestica 26.32 7.00e-28 116.00
IUUC-Mmu-064020 Mus musculus 27.38 6.00e-27 113.00
IUUC-Mpu-066320 Mustela putorius furo 27.71 8.00e-26 109.00
IUUC-Mlu-067472 Myotis lucifugus 26.57 3.00e-27 114.00
IUUC-Nfi-068568 Neosartorya fischeri 36.46 8.00e-56 209.00
IUUC-Ncr-068765 Neurospora crassa 34.20 1.00e-58 219.00
IUUC-Nle-070035 Nomascus leucogenys 27.65 4.00e-28 117.00
IUUC-Ont-072419 Oreochromis niloticus 25.39 1.00e-26 112.00
IUUC-Oan-072727 Ornithorhynchus anatinus 27.41 6.00e-26 109.00
IUUC-Ocu-074576 Oryctolagus cuniculus 26.89 7.00e-27 113.00
IUUC-Ola-087487 Oryzias latipes 24.44 3.00e-24 104.00
IUUC-Oga-089079 Otolemur garnettii 27.38 1.00e-29 122.00
IUUC-Oar-089306 Ovis aries 27.38 1.00e-29 122.00
IUUC-Ptr-090536 Pan troglodytes 27.27 1.00e-27 115.00
IUUC-Pan-092172 Papio anubis 27.38 3.00e-29 120.00
IUUC-Psi-092953 Pelodiscus sinensis 27.47 6.00e-25 106.00
IUUC-Pma-094312 Petromyzon marinus 25.74 1.00e-20 92.00
IUUC-Pno-094911 Phaeosphaeria nodorum 36.95 2.00e-54 204.00
IUUC-Pfo-096200 Poecilia formosa 27.17 1.00e-25 108.00
IUUC-Pab-098151 Pongo abelii 27.65 6.00e-28 116.00
IUUC-Pca-100396 Procavia capensis 49.06 3.00e-13 67.80
IUUC-Pva-103093 Pteropus vampyrus 28.52 5.00e-29 120.00
IUUC-Pgr-103679 Puccinia graminis 36.65 6.00e-24 103.00
IUUC-Ptt-103709 Puccinia triticina 34.88 2.00e-20 91.70
IUUC-Pte-104251 Pyrenophora teres 35.21 4.00e-61 227.00
IUUC-Pyt-104694 Pyrenophora triticirepentis 34.96 1.00e-61 229.00
IUUC-Rno-105275 Rattus norvegicus 27.38 1.00e-27 115.00
IUUC-Sha-106927 Sarcophilus harrisii 26.74 2.00e-25 108.00
IUUC-Sja-107859 Schizosaccharomyces japonicus 32.57 8.00e-42 162.00
IUUC-Spo-108333 Schizosaccharomyces pombe 35.15 2.00e-50 190.00
IUUC-Ssl-108525 Sclerotinia sclerotiorum 36.11 8.00e-54 202.00
IUUC-Sar-113551 Sorex araneus 27.11 7.00e-26 109.00
IUUC-Sre-115010 Sporisorium reilianum 32.21 9.00e-23 99.80
IUUC-Ssc-116366 Sus scrofa 27.38 5.00e-29 120.00
IUUC-Tgu-116550 Taeniopygia guttata 27.11 4.00e-25 107.00
IUUC-Tru-117683 Takifugu rubripes 23.79 3.00e-24 104.00
IUUC-Tsy-119199 Tarsius syrichta 26.79 7.00e-27 113.00
IUUC-Tni-120765 Tetraodon nigroviridis 27.57 4.00e-25 107.00
IUUC-Tre-122061 Trichoderma reesei 38.50 8.00e-60 223.00
IUUC-Tvi-122365 Trichoderma virens 37.30 3.00e-61 227.00
IUUC-Tme-127104 Tuber melanosporum 32.04 3.00e-54 204.00
IUUC-Tbe-127233 Tupaia belangeri 26.12 2.00e-20 91.70
IUUC-Ttr-128960 Tursiops truncatus 27.44 1.00e-28 119.00
IUUC-Uma-129613 Ustilago maydis 33.12 3.00e-24 104.00
IUUC-Vda-129759 Verticillium dahliae 34.80 3.00e-49 188.00
IUUC-Vpa-130600 Vicugna pacos 27.38 6.00e-28 116.00
IUUC-Xtr-131863 Xenopus tropicalis 25.81 3.00e-25 107.00
IUUC-Xma-133716 Xiphophorus maculatus 26.62 7.00e-26 109.00
IUUC-Yli-134599 Yarrowia lipolytica 39.55 9.00e-72 262.00
Created Date 25-Jun-2017

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