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Basic Information Integrated Annotations

Tag Content
UUCD2 ID IUUC-Cel-018704
UUCD1 version UUC-CaE-00271
Ensembl Protein ID F13D12.7a.1
UniProt Accession P17343; Q19394; Q968T1; GBB1_CAEEL
Genbank Protein ID CAA35532.1; AAK55963.1; CAA88948.1
Protein Name Guanine nucleotide-binding protein subunit beta-1
Genbank Nucleotide ID X17497; AF291846; Z49127
Gene Name gpb-1; F13D12.7
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
WBGene00001679 F13D12.7a.1 F13D12.7a.1
Annotation
mRNA Expression
GEO
DNA & RNA Element
microRNARAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
dbPAFdbPTMPhospho.ELMPHOSIDA
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 7.10e-39 130.4 141 175
UBD/Beta-Prp 7.00e-52 176.7 47 268
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sdtllvsGsdDgtikvWDlrtgv 34
    gHt+ +c++f +d+ +v++s+D t+ +WD+ tg
   Q: 141 GHTGYLSCCRFlDDNQIVTSSGDMTCALWDIETGQ 175
    8**********988****************99986 PP
   


   UBD/Beta-Prp

   S: 44   llrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee...tlsghdg 138
    + r+l gh a+++a+ + +d+ lv++s+D+ + vwd t vh++ ++ v+++++ psg++++ G+ d++ ++ l+t++ l gh+g
   Q: 47 TRRTLRGHLAKIYAMHWASDSRNLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGSFVACGGLDNICSIYSLKTREGNVRvsrELPGHTG 144
    5689*****************************************************************************99877666779****** PP
   S: 139 vvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnder 236
    +c ++ + +n +v++s D t+ lWd++tg+ + +tg ht++v sls++++ + ++sg++d + klwd++ g c +t+ gh++ ++ v+f+p ++
   Q: 145 YLSCCRFLD-DNQIVTSSGDMTCALWDIETGQQCTAFTG-HTGDVMSLSLSPDFRTFISGACDASAKLWDIRDGMCKQTFPGHESDINAVAFFPSGNA 240
    *******99.78899***********************9.********************************************************** PP
   S: 237 lvsgssDgsiriWdlrsgdllktlqlhn 264
    +++gs+D + r++d+r ++ l ++++ n
   Q: 241 FATGSDDATCRLFDIRADQELAMYSHDN 268
    *********************9999854 PP
   

Organism Caenorhabditis elegans
Functional Description
(View)

Functional Description



     Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. In the early embryo, controls the magnitude of the forces acting on centrosomes but is not required for generating asymmetric forces (PubMed:14534135).
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. In the early embryo, controls the magnitude of the forces acting on centrosomes but is not required for generating asymmetric forces (PubMed:14534135).
Protein Sequence
(Fasta)
MSELDQLRQE AEQLKSQIRE ARKSANDTTL ATVASNLEPI GRIQMRTRRT LRGHLAKIYA 60
MHWASDSRNL VSASQDGKLI VWDSYTTNKV HAIPLRSSWV MTCAYAPSGS FVACGGLDNI 120
It may take some time, please wait.

Protein Fasta Sequence



>IUUC-Cel-018704|E3,WD_repeat;UBD,Beta-Prp|Caenorhabditis elegans
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GTTTGCAGAC CGTCATTCTG TACTTCCTGA TCAGCAGCTT GGTCTCACCG TCTTTGCCAA 60
GTTGACGTCG GTCGAGGGGT TTTAATTAAA AGGGTTAGTG ATATAGATTT CTTTCTAGTA 120
It may take some time, please wait.

Nucleotide Fasta Sequence



>IUUC-Cel-018704|E3,WD_repeat;UBD,Beta-Prp|Caenorhabditis elegans
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0131--Cell cycle
KW-0132--Cell division
KW-0181--Complete proteome
KW-0498--Mitosis
KW-1185--Reference proteome
KW-0677--Repeat
KW-0807--Transducer
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001632--Gprotein_B
IPR016346--Guanine_nucleotide-bd_bsu
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00319--GPROTEINB
PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005834--C:heterotrimeric G-protein complex
GO:0004871--F:signal transducer activity
GO:0051301--P:cell division
GO:0009792--P:embryo development ending in birth or egg hatching
GO:0000132--P:establishment of mitotic spindle orientation
GO:0007067--P:mitotic nuclear division
GO:0040013--P:negative regulation of locomotion
GO:0046662--P:regulation of oviposition

KEGG cel:CELE_F13D12.7
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000161 Aegilops tauschii 51.47 4.00e-77 280.00
IUUC-Aml-001727 Ailuropoda melanoleuca 84.83 7.00e-170 588.00
IUUC-Atr-002610 Amborella trichopoda 50.00 7.00e-88 315.00
IUUC-Apl-003811 Anas platyrhynchos 86.47 3.00e-174 602.00
IUUC-Aca-004754 Anolis carolinensis 86.38 9.00e-164 567.00
IUUC-Aly-006025 Arabidopsis lyrata 51.92 6.00e-87 312.00
IUUC-Ath-006617 Arabidopsis thaliana 51.92 2.00e-86 311.00
IUUC-Ago-007831 Ashbya gossypii 38.24 4.00e-70 257.00
IUUC-Acl-008154 Aspergillus clavatus 67.95 6.00e-141 492.00
IUUC-Afl-008568 Aspergillus flavus 68.24 6.00e-143 498.00
IUUC-Afu-008789 Aspergillus fumigatus 67.95 6.00e-141 492.00
IUUC-Ani-009213 Aspergillus nidulans 68.24 4.00e-142 496.00
IUUC-Ang-009836 Aspergillus niger 68.53 2.00e-143 499.00
IUUC-Aor-010165 Aspergillus oryzae 68.24 6.00e-143 498.00
IUUC-Ate-010520 Aspergillus terreus 61.44 3.00e-112 396.00
IUUC-Ame-011092 Astyanax mexicanus 85.59 0.00e+00 627.00
IUUC-Bgr-012079 Blumeria graminis 66.96 1.00e-136 478.00
IUUC-Bta-013430 Bos taurus 85.45 4.00e-171 592.00
IUUC-Bci-013621 Botrytis cinerea 67.35 3.00e-136 476.00
IUUC-Bdi-014785 Brachypodium distachyon 51.28 8.00e-89 319.00
IUUC-Bol-015657 Brassica oleracea 52.24 3.00e-88 317.00
IUUC-Bra-017618 Brassica rapa 52.24 4.00e-88 317.00
IUUC-Cja-019794 Callithrix jacchus 85.45 4.00e-171 592.00
IUUC-Cfa-020395 Canis familiaris 84.83 7.00e-170 588.00
IUUC-Cpo-021865 Cavia porcellus 85.45 6.00e-171 591.00
IUUC-Csa-023572 Chlorocebus sabaeus 85.45 4.00e-171 592.00
IUUC-Cho-024766 Choloepus hoffmanni 84.62 1.00e-170 590.00
IUUC-Cin-025309 Ciona intestinalis 80.47 9.00e-171 591.00
IUUC-Csv-026258 Ciona savignyi 80.18 2.00e-169 587.00
IUUC-Cgl-026673 Colletotrichum gloeosporioides 69.30 5.00e-142 495.00
IUUC-Cne-026811 Cryptococcus neoformans 68.47 8.00e-144 501.00
IUUC-Dre-027412 Danio rerio 86.47 0.00e+00 630.00
IUUC-Dno-029001 Dasypus novemcinctus 85.45 1.00e-170 591.00
IUUC-Dor-030322 Dipodomys ordii 76.78 1.00e-148 517.00
IUUC-Dse-031388 Dothistroma septosporum 68.82 6.00e-143 498.00
IUUC-Dme-031748 Drosophila melanogaster 85.88 0.00e+00 625.00
IUUC-Ete-032710 Echinops telfairi 84.74 3.00e-162 562.00
IUUC-Eca-034149 Equus caballus 85.45 4.00e-171 592.00
IUUC-Eeu-034978 Erinaceus europaeus 84.25 2.00e-140 489.00
IUUC-Fca-036537 Felis catus 85.45 4.00e-171 592.00
IUUC-Fal-037616 Ficedula albicollis 87.00 8.00e-165 571.00
IUUC-Fox-037946 Fusarium oxysporum 69.59 1.00e-137 481.00
IUUC-Fso-038136 Fusarium solani 69.59 1.00e-137 481.00
IUUC-Gmo-039556 Gadus morhua 86.38 7.00e-173 598.00
IUUC-Ggr-039969 Gaeumannomyces graminis 68.13 9.00e-140 488.00
IUUC-Gga-040249 Gallus gallus 87.00 8.00e-165 571.00
IUUC-Gac-041805 Gasterosteus aculeatus 85.76 5.00e-173 598.00
IUUC-Gma-042671 Glycine max 48.30 1.00e-91 328.00
IUUC-Ggo-044543 Gorilla gorilla 85.45 4.00e-171 592.00
IUUC-Hsa-046432 Homo sapiens 85.45 4.00e-171 592.00
IUUC-Hvu-047596 Hordeum vulgare 45.01 7.00e-88 315.00
IUUC-Itr-048049 Ictidomys tridecemlineatus 85.29 2.00e-176 609.00
IUUC-Kpa-049192 Komagataella pastoris 37.60 8.00e-64 236.00
IUUC-Lch-049422 Latimeria chalumnae 86.76 3.00e-174 602.00
IUUC-Lpe-051040 Leersia perrieri 51.60 2.00e-89 321.00
IUUC-Loc-052939 Lepisosteus oculatus 86.18 0.00e+00 628.00
IUUC-Lma-052985 Leptosphaeria maculans 68.86 2.00e-141 493.00
IUUC-Laf-053865 Loxodonta africana 85.45 6.00e-171 591.00
IUUC-Mcc-055787 Macaca mulatta 84.83 5.00e-170 588.00
IUUC-Meu-056902 Macropus eugenii 85.14 6.00e-171 591.00
IUUC-Mor-057188 Magnaporthe oryzae 68.13 3.00e-139 486.00
IUUC-Mpo-057544 Magnaporthe poae 68.42 3.00e-140 490.00
IUUC-Mtr-058752 Medicago truncatula 46.76 2.00e-90 324.00
IUUC-Mla-059086 Melampsora laricipopulina 73.19 9.00e-154 534.00
IUUC-Mga-060050 Meleagris gallopavo 86.73 2.00e-163 566.00
IUUC-Mvi-060482 Microbotryum violaceum 71.69 3.00e-152 530.00
IUUC-Mmr-061015 Microcebus murinus 85.45 4.00e-171 592.00
IUUC-Mdo-062734 Monodelphis domestica 85.14 6.00e-171 591.00
IUUC-Mmu-063737 Mus musculus 85.45 9.00e-171 591.00
IUUC-Mac-064871 Musa acuminata 46.61 2.00e-85 307.00
IUUC-Mpu-066358 Mustela putorius furo 84.83 7.00e-170 588.00
IUUC-Mlu-067912 Myotis lucifugus 85.76 2.00e-171 593.00
IUUC-Nfi-068332 Neosartorya fischeri 67.95 2.00e-140 490.00
IUUC-Ncr-068650 Neurospora crassa 65.50 2.00e-132 463.00
IUUC-Nle-069612 Nomascus leucogenys 84.83 5.00e-170 588.00
IUUC-Opr-070866 Ochotona princeps 85.45 4.00e-171 592.00
IUUC-Ont-071775 Oreochromis niloticus 86.47 0.00e+00 629.00
IUUC-Oan-072780 Ornithorhynchus anatinus 85.88 9.00e-174 601.00
IUUC-Ocu-074344 Oryctolagus cuniculus 85.45 4.00e-171 592.00
IUUC-Oba-075818 Oryza barthii 44.27 9.00e-87 312.00
IUUC-Obr-076229 Oryza brachyantha 51.28 2.00e-86 311.00
IUUC-Ogl-077730 Oryza glaberrima 45.82 3.00e-90 323.00
IUUC-Ogu-078583 Oryza glumaepatula 51.92 2.00e-71 261.00
IUUC-Oin-079661 Oryza indica 45.55 4.00e-87 313.00
IUUC-Olo-080225 Oryza longistaminata 51.92 2.00e-71 261.00
IUUC-Oni-082161 Oryza nivara 45.55 1.00e-89 322.00
IUUC-Opu-084072 Oryza punctata 45.55 9.00e-90 322.00
IUUC-Oru-084316 Oryza rufipogon 45.55 4.00e-87 313.00
IUUC-Osa-085380 Oryza sativa 45.55 4.00e-87 313.00
IUUC-Ola-087490 Oryzias latipes 85.58 2.00e-173 600.00
IUUC-Oga-089046 Otolemur garnettii 85.45 4.00e-171 592.00
IUUC-Oar-089360 Ovis aries 84.83 5.00e-170 588.00
IUUC-Ptr-091444 Pan troglodytes 85.45 4.00e-171 592.00
IUUC-Pan-092045 Papio anubis 85.45 4.00e-171 592.00
IUUC-Psi-093718 Pelodiscus sinensis 87.00 8.00e-165 571.00
IUUC-Pma-094748 Petromyzon marinus 88.49 1.00e-137 480.00
IUUC-Pno-095135 Phaeosphaeria nodorum 68.86 1.00e-141 494.00
IUUC-Ppa-095726 Physcomitrella patens 46.26 3.00e-81 293.00
IUUC-Pfo-097028 Poecilia formosa 86.47 0.00e+00 628.00
IUUC-Pab-097601 Pongo abelii 84.83 6.00e-170 588.00
IUUC-Pop-099370 Populus trichocarpa 51.61 3.00e-90 323.00
IUUC-Pca-100940 Procavia capensis 85.45 4.00e-171 592.00
IUUC-Ppe-102016 Prunus persica 47.18 3.00e-91 327.00
IUUC-Pva-102229 Pteropus vampyrus 85.76 3.00e-170 589.00
IUUC-Pgr-103321 Puccinia graminis 73.19 2.00e-154 536.00
IUUC-Ptt-103728 Puccinia triticina 73.19 2.00e-154 536.00
IUUC-Pte-104053 Pyrenophora teres 67.85 1.00e-141 494.00
IUUC-Pyt-104426 Pyrenophora triticirepentis 62.61 3.00e-128 449.00
IUUC-Rno-106104 Rattus norvegicus 85.45 4.00e-171 592.00
IUUC-Sce-106298 Saccharomyces cerevisiae 36.10 2.00e-68 251.00
IUUC-Sha-107632 Sarcophilus harrisii 85.14 6.00e-171 591.00
IUUC-Sja-107891 Schizosaccharomyces japonicus 36.45 5.00e-60 223.00
IUUC-Spo-108352 Schizosaccharomyces pombe 42.67 5.00e-71 259.00
IUUC-Ssl-108539 Sclerotinia sclerotiorum 67.54 3.00e-136 476.00
IUUC-Smo-108835 Selaginella moellendorffii 45.96 2.00e-78 284.00
IUUC-Sit-110441 Setaria italica 51.60 3.00e-89 320.00
IUUC-Sly-111784 Solanum lycopersicum 50.65 9.00e-87 312.00
IUUC-Stu-112400 Solanum tuberosum 50.65 1.00e-86 312.00
IUUC-Sar-113642 Sorex araneus 87.82 1.00e-146 511.00
IUUC-Sbi-114038 Sorghum bicolor 50.96 5.00e-88 316.00
IUUC-Sre-115035 Sporisorium reilianum 70.87 1.00e-146 510.00
IUUC-Ssc-115595 Sus scrofa 85.45 4.00e-171 592.00
IUUC-Tgu-117198 Taeniopygia guttata 87.00 8.00e-165 571.00
IUUC-Tru-117793 Takifugu rubripes 86.47 0.00e+00 629.00
IUUC-Tsy-119354 Tarsius syrichta 83.90 7.00e-168 581.00
IUUC-Tni-120216 Tetraodon nigroviridis 84.83 8.00e-171 591.00
IUUC-Tca-121224 Theobroma cacao 51.94 5.00e-90 323.00
IUUC-Tre-122156 Trichoderma reesei 69.30 2.00e-141 494.00
IUUC-Tvi-122640 Trichoderma virens 69.30 2.00e-141 494.00
IUUC-Tae-124407 Triticum aestivum 45.28 4.00e-88 317.00
IUUC-Tur-126755 Triticum urartu 51.12 1.00e-88 320.00
IUUC-Tme-126886 Tuber melanosporum 70.96 2.00e-141 494.00
IUUC-Tbe-127694 Tupaia belangeri 69.04 2.00e-129 453.00
IUUC-Ttr-128403 Tursiops truncatus 85.45 4.00e-171 592.00
IUUC-Uma-129589 Ustilago maydis 71.47 9.00e-147 511.00
IUUC-Vda-129855 Verticillium dahliae 73.11 2.00e-134 469.00
IUUC-Vvi-131162 Vitis vinifera 51.61 8.00e-90 322.00
IUUC-Xtr-131924 Xenopus tropicalis 86.38 1.00e-163 568.00
IUUC-Xma-133743 Xiphophorus maculatus 86.47 0.00e+00 628.00
IUUC-Yli-134396 Yarrowia lipolytica 35.01 5.00e-66 243.00
IUUC-Zma-135893 Zea mays 50.64 1.00e-87 315.00
Created Date 25-Jun-2017

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