iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSRNOG00000017191.6	ENSRNOT00000023100.5	ENSRNOP00000023099.4
ENSRNOG00000017191.6	ENSRNOT00000082645.1	ENSRNOP00000073760.1
ENSRNOG00000017191.6	ENSRNOT00000030827.6	ENSRNOP00000038739.6

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	8.30e-06	26.2	10	79
E3 activity/RING/RING	5.30e-09	36.9	15	59

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 3    peeflCpIslelMrdPvvlpsGitydrssIekwlasggk.....tcPvtrqplteedlvPnltlrrliqa 67
            ee  CpI l+lM +Pv   +G+++ +++I    +s++       cPv+r +   ++l Pn  + +++q+
   Q: 10   KEEVTCPICLDLMVEPVSGDCGHSFCQACITLNYESSKCnqdefICPVCRVSYLFKNLRPNRHVANIVQR 79
           68999*************************876655555678899****************988877765 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           C+iCl+ + + p++++CgH f++ C+  ++  +++  + ef+CP+Cr
   Q: 15   CPICLDLMVE-PVSGDCGHSFCQACItLNY-ESSKCNQDEFICPVCR 59
           ********99.***************9999.99999**********8 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MASEFVMNLK EEVTCPICLD LMVEPVSGDC GHSFCQACIT LNYESSKCNQ DEFICPVCRV 60
SYLFKNLRPN RHVANIVQRL KEFKSSPEEE PKVLSCARHG EKLQLFCKKD MMPICWLCER 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCTCTGCACA GGGTTCATTC TGATCCTCCA TCTCTTACTT GGCCCCTTTC CCCATCCCTA 60
TCACATAGGC ACCAGTGCAG AAGTGTGAGG AGTCAAGACA GACAGACACA GGATCACAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR003877--SPRY_dom
IPR032917--TRIM5
IPR027370--Znf-RING_LisH
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00622--SPRY
PF00643--zf-B_box
PF13445--zf-RING_UBOX

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005622--C:intracellular
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0006914--P:autophagy
GO:0051607--P:defense response to virus
GO:0045087--P:innate immune response

KEGG

rno:308906

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Cre-022597	Chlamydomonas reinhardtii	30.86	8.00e-09	54.70
IUUC-Dor-030700	Dipodomys ordii	48.82	3.00e-130	458.00
IUUC-Mmr-061336	Microcebus murinus	51.27	2.00e-130	459.00
IUUC-Mmu-063453	Mus musculus	79.45	0.00e+00	817.00
IUUC-Ocu-073956	Oryctolagus cuniculus	50.49	6.00e-136	478.00
IUUC-Pma-094336	Petromyzon marinus	35.97	1.00e-19	88.20
IUUC-Tsy-119055	Tarsius syrichta	49.90	2.00e-136	479.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence