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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Mmu-063298
Ensembl Protein ID ENSMUSP00000137726.1
UniProt Accession M0QWN7; M0QWN7_MOUSE
Genbank Protein ID ENSMUSP00000137726
Protein Name Ubiquitin-specific peptidase 35
Genbank Nucleotide ID AC155933
Gene Name Usp35
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000035713.15 ENSMUST00000139582.8 ENSMUSP00000137726.1
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
AREsitemicroRNATRANSFACRAID2
Post-translational Modifications (PTMs)
dbPAFPhosphositePlusPHOSIDA
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 4.40e-83 280.4 442 918
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/USP
   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqq 90
           Gl NlgNtCY+NSvLQ+L++ +++r+++l+     l e+    ++++l+++lq lf+ l +s++ a+sp+++l+a +   + fs   qq
   Q: 442  GLINLGNTCYVNSVLQALFMASDFRHCVLR-----LTEN----NSQPLMTKLQWLFAFLEHSQRPAISPENFLSASW--TPWFSPGTQQ 519
           9*****************************.....4433....3579***************************998..677******* PP
   S: 91   DaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgk 179
           D++E+l++lld+l+ee      k+ ++ +++ k+++  + +e+ +++n + ++++F+g++ ++i cl+c nvssree f+dlsl++p  
   Q: 520  DCSEYLKYLLDRLHEEE-----KTGMRICQKLKQSSLPSPQEELPSSNATSVEKMFGGKIVTRICCLHCLNVSSREEAFTDLSLAFPPP 603
           *****************.....678888888888888889999********************************************88 PP
   S: 180  eetkke................................................................................... 185
           e + ++                                                                                   
   Q: 604  ERSRHRrlgsvmlptedvrvqeltlaprapgaqrqrkrcitgdaprtgldsegvdtigtggrsgqekvereqagkekevaedreeegtr 692
           87766689********************************************************************************* PP
   S: 186  ...........................................................slqdcLesftkeeelegenkyycekckkkq 215
                                                                      s+ d+ + f ++e+l+ en+yyce+c ++q
   Q: 693  eeekeegeekdkekekkedekekeaengkekegdslgpgthreaatppreqtcgpegsrSVLDLVNYFLSPERLTAENRYYCESCASLQ 781
           ***************************************************************************************** PP
   S: 216  eaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspeekqkekkkYeLiavvvHsG.slssGHYvayvkn.. 301
           +aek ++l++ P++Lil L Rfsf+ ++++r+ki + v++pl L l     +        + Y+L++vvvHsG s++sGHY++y+++  
   Q: 782  DAEKVVELSQGPRYLILTLLRFSFDLRTMRRRKILDDVTIPLLLRLPLAGGQ-------GQAYDLCSVVVHSGvSSESGHYYCYAREga 863
           *****************************************99999844444.......89**************************99 PP
   S: 302  ..............ekgkWllfdDskVtevkeeevleetg....staYvlfYkrr 338
                          +++W+lf+D++V+ ++ e+v + t+    +taYvlfY++r
   Q: 864  arpapvlgsterpePENQWYLFNDTRVSYSSFESVSNVTSffpkDTAYVLFYRQR 918
           999999999998888999*******************999************985 PP
   
Organism Mus musculus
Protein Sequence
(Fasta)
MDKILEAVVT SSYPASVKQG LVRRVLEAAR QPLEREQCLA LLALGARLYV GGTEELPRRV 60
GCQLLHVAGR HHPDVFAEFF SARRVLRLLQ GGAGPPGARA LACVQLGLQL LPDGPAADEV 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-063298|DUB,USP|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GCACTGCCCA GGTCCATCTA GGGTTGTGCG GAGCGGGGTG GGTGGAGTTG GACATCACAA 60
AGTAGCAGCA GCATCCCTGC GGTCTGGGAC CCCTCGGTAG GGGAGCGGAG GACCCGCCCT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-063298|DUB,USP|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
Interpro

IPR016024--ARM-type_fold
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
Pfam

PF00443--UCH
Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process
KEGG mmu:244144
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001744 Ailuropoda melanoleuca 82.06 0.00e+00 1303.00
IUUC-Apl-004121 Anas platyrhynchos 60.82 0.00e+00 1105.00
IUUC-Aca-005070 Anolis carolinensis 65.51 4.00e-167 581.00
IUUC-Bta-012545 Bos taurus 92.02 0.00e+00 1160.00
IUUC-Cja-019731 Callithrix jacchus 92.57 0.00e+00 1169.00
IUUC-Cfa-020095 Canis familiaris 87.00 0.00e+00 1494.00
IUUC-Cpo-021961 Cavia porcellus 89.20 0.00e+00 1169.00
IUUC-Csa-023167 Chlorocebus sabaeus 91.04 0.00e+00 1163.00
IUUC-Dno-029186 Dasypus novemcinctus 81.60 0.00e+00 832.00
IUUC-Dor-030538 Dipodomys ordii 97.74 0.00e+00 978.00
IUUC-Dme-031871 Drosophila melanogaster 32.41 8.00e-46 179.00
IUUC-Ete-032512 Echinops telfairi 88.54 4.00e-105 375.00
IUUC-Eca-033279 Equus caballus 95.93 0.00e+00 912.00
IUUC-Eeu-035120 Erinaceus europaeus 71.49 0.00e+00 830.00
IUUC-Fca-035969 Felis catus 84.52 0.00e+00 1226.00
IUUC-Fal-037625 Ficedula albicollis 71.34 0.00e+00 909.00
IUUC-Gga-040767 Gallus gallus 69.01 0.00e+00 914.00
IUUC-Ggo-045323 Gorilla gorilla 90.27 0.00e+00 934.00
IUUC-Hsa-046124 Homo sapiens 92.22 0.00e+00 1156.00
IUUC-Itr-048704 Ictidomys tridecemlineatus 86.76 0.00e+00 1563.00
IUUC-Lch-049513 Latimeria chalumnae 55.61 0.00e+00 1003.00
IUUC-Laf-053999 Loxodonta africana 87.89 0.00e+00 1131.00
IUUC-Mcc-055266 Macaca mulatta 91.08 0.00e+00 1141.00
IUUC-Meu-056906 Macropus eugenii 76.64 0.00e+00 1001.00
IUUC-Mga-059595 Meleagris gallopavo 71.78 0.00e+00 889.00
IUUC-Mmr-061720 Microcebus murinus 90.12 0.00e+00 722.00
IUUC-Mdo-062167 Monodelphis domestica 75.76 0.00e+00 1005.00
IUUC-Mpu-066195 Mustela putorius furo 91.65 0.00e+00 1150.00
IUUC-Mlu-067583 Myotis lucifugus 78.13 0.00e+00 1067.00
IUUC-Opr-070454 Ochotona princeps 91.33 1.00e-160 560.00
IUUC-Ocu-074121 Oryctolagus cuniculus 85.60 0.00e+00 958.00
IUUC-Oga-088593 Otolemur garnettii 92.25 0.00e+00 1147.00
IUUC-Oar-090140 Ovis aries 91.72 0.00e+00 1145.00
IUUC-Pan-092168 Papio anubis 91.34 0.00e+00 1165.00
IUUC-Psi-093707 Pelodiscus sinensis 67.56 0.00e+00 913.00
IUUC-Pab-097614 Pongo abelii 91.52 0.00e+00 1153.00
IUUC-Pca-100683 Procavia capensis 87.03 0.00e+00 1125.00
IUUC-Pva-103146 Pteropus vampyrus 78.86 0.00e+00 1334.00
IUUC-Rno-105061 Rattus norvegicus 96.33 0.00e+00 1739.00
IUUC-Sha-106686 Sarcophilus harrisii 74.02 0.00e+00 971.00
IUUC-Tgu-117024 Taeniopygia guttata 63.78 0.00e+00 1155.00
IUUC-Tsy-119505 Tarsius syrichta 77.86 6.00e-171 594.00
Created Date 25-Jun-2017

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