iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Cancer Mutation
TCGA	ICGC	COSMIC	CGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	TCGA	ICGC
COSMIC	HPM
DNA & RNA Element
miRTarBase	microRNA	TRANSFAC	TargetScan
RepTar	miRcode	RAID2
Protein-protein Interaction
IID	Mentha	InWeb_IM
Disease-associated Variation
GWASdb
Post-translational Modifications (PTMs)
dbPAF	PhosphositePlus	dbPTM	HPRD
DNA Methylation
TCGA	ICGC	COSMIC
Protein Expression/Proteomics
THPA	GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
ULD/UDP/UBQ/UBQ_Other	5.60e-07	31.0	33	101

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

ULD/UDP/UBQ/UBQ_Other

   S: 3    vtvksldgs.eltlkvnpsd.tVaeLKekiekklgippeqqrLiykGkiLeddktLadyglkdgstihllek 72
           v+vk++ +  ++ +    +d +V ++Ke++  ++  +++q  L++ G +L+d++tL++ g++dg ti+l+ k
   Q: 33   VIVKTAGNQkDFMVA---DDiSVRQFKEMLLAHFQCQMDQLVLVFMGCLLKDHDTLSQRGIMDGHTIYLVIK 101
           567777776555544...666************************************************987 PP

Organism

Homo sapiens

Protein Sequence
(Fasta)

MWHAISRTSR MSQSGCPSGL LADKNISSSA TRVIVKTAGN QKDFMVADDI SVRQFKEMLL 60
AHFQCQMDQL VLVFMGCLLK DHDTLSQRGI MDGHTIYLVI KSKQGSRSLA HSFRDLPTND 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CACTTTGTCC ACCATGGGTG AATTATGAAT CAGTAGCTAT GCCAGGCCTC AGCTGGGCCA 60
CATCTGGAGA ACTGGGGTGA GGGCACAACA TCACAAAATA TCTGGCCCCA GTCTGGTCAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0621--Polymorphism
KW-1185--Reference proteome

Interpro

IPR015496--Ubiquilin
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom

PROSITE

PS50053--UBIQUITIN_2

Pfam

PF00240--ubiquitin

SMART

SM00213--UBQ

KEGG

hsa:143630

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001843	Ailuropoda melanoleuca	71.55	1.00e-166	579.00
IUUC-Bta-013133	Bos taurus	68.84	7.00e-165	573.00
IUUC-Cfa-021207	Canis familiaris	72.63	1.00e-153	536.00
IUUC-Cpo-021799	Cavia porcellus	68.54	5.00e-116	410.00
IUUC-Dno-029619	Dasypus novemcinctus	69.68	4.00e-160	558.00
IUUC-Ete-032987	Echinops telfairi	58.56	2.00e-128	452.00
IUUC-Eca-034256	Equus caballus	69.87	1.00e-168	586.00
IUUC-Eeu-034870	Erinaceus europaeus	60.82	6.00e-73	268.00
IUUC-Fca-035660	Felis catus	72.84	1.00e-160	560.00
IUUC-Ggo-045615	Gorilla gorilla	97.47	0.00e+00	909.00
IUUC-Itr-047957	Ictidomys tridecemlineatus	68.09	2.00e-162	566.00
IUUC-Mcc-055287	Macaca mulatta	86.32	0.00e+00	765.00
IUUC-Meu-056667	Macropus eugenii	49.83	9.00e-64	237.00
IUUC-Mmu-064356	Mus musculus	58.95	1.00e-130	460.00
IUUC-Mpu-066627	Mustela putorius furo	70.53	3.00e-162	565.00
IUUC-Nle-069185	Nomascus leucogenys	92.84	0.00e+00	854.00
IUUC-Opr-070843	Ochotona princeps	64.95	1.00e-140	493.00
IUUC-Ocu-074622	Oryctolagus cuniculus	72.75	0.00e+00	630.00
IUUC-Oga-088463	Otolemur garnettii	70.78	6.00e-174	604.00
IUUC-Oar-090390	Ovis aries	68.21	8.00e-161	560.00
IUUC-Pan-091893	Papio anubis	86.78	4.00e-121	427.00
IUUC-Rno-105287	Rattus norvegicus	59.14	3.00e-123	435.00
IUUC-Sha-106742	Sarcophilus harrisii	41.86	5.00e-80	292.00
IUUC-Ssc-116230	Sus scrofa	60.44	4.00e-136	478.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence