iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Details
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Spo-108339

UUCD1 version

UUC-ScP-00036

Ensembl Protein ID

SPAC1687.05.1:pep

UniProt Accession

O94451; PLI1_SCHPO

Genbank Protein ID

CAA22599.1; BAA87094.1

Protein Name

E3 SUMO-protein ligase pli1

Genbank Nucleotide ID

CU329670; AB027790

Gene Name

pli1; SPAC1687.05

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
SPAC1687.05	SPAC1687.05.1	SPAC1687.05.1:pep

Annotation

mRNA Expression
GEO
Protein-protein Interaction
iRefIndex	HINT	Mentha
Post-translational Modifications (PTMs)
dbPAF	dbPTM	UniProt
Protein Expression/Proteomics

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E3 activity/RING/RING	RING	15359282; 19906698

Classification

Family	E-value	Score	Start	End
E3 activity/RING/RING	0.0001	20.8	305	347

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlC 45
           C++ +++++ +++++ C+H+ ++d   ++ + +n++ ++++CP+C
   Q: 305  CPLSFSRISLPVRSVFCKHIQCFDA-SAF-LEMNKQTPSWMCPVC 347
           ********99999999***999999.455.77799********** PP

Organism

Schizosaccharomyces pombe

Functional Description
(View)

Acts as an E3 ligase mediating SUMO/Smt3 attachment to other proteins. Involved in the maintenance of the centromere and in telomere length. Regulates recombination, via extension sumoylation, particularly within the heterochromatin repeats.

Protein Sequence
(Fasta)

MNQANFLQEL PNVLKRLETG LIIPQLKDIL RVFGLRLSGT KAELITRIKQ LIERIAIENN 60
TTSWEALKKA IDGDVTSAVC ILKYNTYQIY SAAAPIAPPS SASGNRSYSR PFAPVVHSRI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCTAAAATTT GATTTCTTTG TCTTTCAAAT ACCTATACGG AAGCAGTCAT TGCATATAAC 60
ATATGTGTAA ATCGACGGTT TAGGCAAGCA GTCTAAAAAC TCAATGAACC AGGCGAACTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0436--Ligase
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR023321--PINIT
IPR003034--SAP_dom
IPR027229--SIZ1/SIZ2/Pli1/Gei17
IPR004181--Znf_MIZ
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51466--PINIT
PS50800--SAP
PS51044--ZF_SP_RING

Pfam

PF14324--PINIT
PF02037--SAP
PF02891--zf-MIZ

SMART

SM00513--SAP

Gene Ontology

GO:0005634--C:nucleus
GO:0035861--C:site of double-strand break
GO:0016874--F:ligase activity
GO:0061665--F:SUMO ligase activity
GO:0008270--F:zinc ion binding
GO:0030999--P:linear element assembly
GO:2000042--P:negative regulation of double-strand break repair via homologous recombination
GO:0016925--P:protein sumoylation
GO:0007131--P:reciprocal meiotic recombination
GO:0000019--P:regulation of mitotic recombination
GO:0010520--P:regulation of reciprocal meiotic recombination
GO:0032207--P:regulation of telomere maintenance via recombination

KEGG

spo:SPAC1687.05

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000547	Aegilops tauschii	27.27	4.00e-20	91.30
IUUC-Aml-001984	Ailuropoda melanoleuca	28.57	1.00e-28	119.00
IUUC-Atr-002447	Amborella trichopoda	40.20	6.00e-21	94.40
IUUC-Apl-003376	Anas platyrhynchos	28.97	2.00e-28	118.00
IUUC-Aca-004903	Anolis carolinensis	28.97	2.00e-28	118.00
IUUC-Aly-006247	Arabidopsis lyrata	25.59	7.00e-24	103.00
IUUC-Ath-006888	Arabidopsis thaliana	25.89	1.00e-22	99.40
IUUC-Ago-007762	Ashbya gossypii	30.10	9.00e-41	160.00
IUUC-Acl-008204	Aspergillus clavatus	39.03	1.00e-55	208.00
IUUC-Afl-008672	Aspergillus flavus	33.66	9.00e-62	229.00
IUUC-Afu-008758	Aspergillus fumigatus	35.38	5.00e-64	236.00
IUUC-Ani-009389	Aspergillus nidulans	33.97	9.00e-64	235.00
IUUC-Ang-009590	Aspergillus niger	31.95	1.00e-58	219.00
IUUC-Aor-009912	Aspergillus oryzae	31.22	8.00e-53	199.00
IUUC-Ate-010496	Aspergillus terreus	33.24	2.00e-53	201.00
IUUC-Ame-010763	Astyanax mexicanus	34.67	3.00e-30	124.00
IUUC-Bgr-012177	Blumeria graminis	32.80	6.00e-37	146.00
IUUC-Bta-012457	Bos taurus	28.85	6.00e-29	120.00
IUUC-Bci-013700	Botrytis cinerea	32.38	6.00e-56	209.00
IUUC-Bdi-014629	Brachypodium distachyon	25.58	9.00e-20	90.10
IUUC-Bol-015250	Brassica oleracea	31.43	2.00e-25	108.00
IUUC-Bra-017667	Brassica rapa	27.49	3.00e-24	104.00
IUUC-Cel-018231	Caenorhabditis elegans	26.01	4.00e-18	84.70
IUUC-Cja-019111	Callithrix jacchus	26.74	2.00e-28	118.00
IUUC-Cfa-020481	Canis familiaris	28.57	7.00e-29	120.00
IUUC-Cpo-021940	Cavia porcellus	28.85	6.00e-30	123.00
IUUC-Cre-022902	Chlamydomonas reinhardtii	28.72	6.00e-08	50.10
IUUC-Csa-023964	Chlorocebus sabaeus	28.57	8.00e-29	120.00
IUUC-Cho-024816	Choloepus hoffmanni	31.80	6.00e-26	110.00
IUUC-Cin-025791	Ciona intestinalis	27.78	2.00e-30	125.00
IUUC-Csv-026329	Ciona savignyi	35.77	9.00e-22	96.70
IUUC-Cgl-026533	Colletotrichum gloeosporioides	29.86	2.00e-53	201.00
IUUC-Cne-026824	Cryptococcus neoformans	29.17	1.00e-25	109.00
IUUC-Cme-027209	Cyanidioschyzon merolae	32.86	1.00e-14	73.20
IUUC-Dre-028069	Danio rerio	30.69	2.00e-31	127.00
IUUC-Dno-029550	Dasypus novemcinctus	28.57	8.00e-29	119.00
IUUC-Dor-030842	Dipodomys ordii	27.07	1.00e-27	116.00
IUUC-Dse-031254	Dothistroma septosporum	30.89	4.00e-54	203.00
IUUC-Dme-032018	Drosophila melanogaster	26.56	8.00e-26	110.00
IUUC-Ete-032543	Echinops telfairi	36.23	4.00e-23	100.00
IUUC-Eca-033639	Equus caballus	28.57	5.00e-29	120.00
IUUC-Eeu-034486	Erinaceus europaeus	28.91	3.00e-26	110.00
IUUC-Fca-035986	Felis catus	28.57	9.00e-29	119.00
IUUC-Fal-036926	Ficedula albicollis	27.86	2.00e-28	119.00
IUUC-Fox-038010	Fusarium oxysporum	28.57	6.00e-16	76.60
IUUC-Fso-038103	Fusarium solani	33.22	1.00e-42	164.00
IUUC-Gmo-038925	Gadus morhua	34.17	2.00e-30	125.00
IUUC-Ggr-039896	Gaeumannomyces graminis	30.87	9.00e-48	182.00
IUUC-Gga-040755	Gallus gallus	25.78	1.00e-28	119.00
IUUC-Gac-041594	Gasterosteus aculeatus	24.57	2.00e-30	125.00
IUUC-Gma-043279	Glycine max	28.51	5.00e-24	104.00
IUUC-Ggo-044666	Gorilla gorilla	27.78	1.00e-26	112.00
IUUC-Hsa-046146	Homo sapiens	28.57	8.00e-29	120.00
IUUC-Hvu-047061	Hordeum vulgare	26.38	3.00e-24	105.00
IUUC-Itr-048994	Ictidomys tridecemlineatus	28.57	3.00e-29	121.00
IUUC-Kpa-049203	Komagataella pastoris	29.07	8.00e-46	177.00
IUUC-Lch-050349	Latimeria chalumnae	29.03	7.00e-30	123.00
IUUC-Lpe-050926	Leersia perrieri	29.52	5.00e-23	101.00
IUUC-Loc-052851	Lepisosteus oculatus	29.41	6.00e-26	110.00
IUUC-Lma-053196	Leptosphaeria maculans	30.10	2.00e-45	175.00
IUUC-Laf-053486	Loxodonta africana	28.22	6.00e-29	120.00
IUUC-Mcc-055123	Macaca mulatta	28.57	8.00e-29	120.00
IUUC-Meu-056468	Macropus eugenii	29.51	5.00e-27	113.00
IUUC-Mor-057185	Magnaporthe oryzae	33.69	3.00e-49	187.00
IUUC-Mpo-057405	Magnaporthe poae	31.32	2.00e-44	171.00
IUUC-Mtr-058267	Medicago truncatula	39.80	1.00e-20	93.20
IUUC-Mla-058882	Melampsora laricipopulina	31.82	1.00e-40	158.00
IUUC-Mga-059790	Meleagris gallopavo	28.97	2.00e-28	118.00
IUUC-Mvi-060421	Microbotryum violaceum	30.36	5.00e-50	190.00
IUUC-Mmr-060785	Microcebus murinus	28.30	2.00e-28	119.00
IUUC-Mdo-061916	Monodelphis domestica	28.09	1.00e-28	119.00
IUUC-Mmu-063170	Mus musculus	28.61	6.00e-29	120.00
IUUC-Mac-065177	Musa acuminata	33.71	1.00e-21	96.30
IUUC-Mpu-066609	Mustela putorius furo	28.57	7.00e-29	120.00
IUUC-Mlu-068029	Myotis lucifugus	27.61	9.00e-30	122.00
IUUC-Nfi-068586	Neosartorya fischeri	35.41	9.00e-62	229.00
IUUC-Ncr-068929	Neurospora crassa	30.74	3.00e-49	187.00
IUUC-Nle-070004	Nomascus leucogenys	28.57	8.00e-29	120.00
IUUC-Opr-070251	Ochotona princeps	34.10	8.00e-26	109.00
IUUC-Ont-072227	Oreochromis niloticus	34.67	2.00e-30	125.00
IUUC-Oan-073567	Ornithorhynchus anatinus	25.54	5.00e-29	120.00
IUUC-Ocu-073833	Oryctolagus cuniculus	28.97	2.00e-28	118.00
IUUC-Oba-075731	Oryza barthii	29.69	2.00e-25	109.00
IUUC-Obr-076179	Oryza brachyantha	30.57	2.00e-26	112.00
IUUC-Ogl-077808	Oryza glaberrima	29.69	2.00e-25	109.00
IUUC-Ogu-078271	Oryza glumaepatula	29.69	2.00e-25	108.00
IUUC-Oin-079070	Oryza indica	29.26	7.00e-25	107.00
IUUC-Olo-080772	Oryza longistaminata	27.23	2.00e-18	85.90
IUUC-Ome-081404	Oryza meridionalis	29.69	2.00e-25	109.00
IUUC-Oni-082285	Oryza nivara	26.51	2.00e-20	92.00
IUUC-Opu-083841	Oryza punctata	29.69	3.00e-25	108.00
IUUC-Oru-084716	Oryza rufipogon	29.26	8.00e-25	107.00
IUUC-Osa-085685	Oryza sativa	29.26	5.00e-25	107.00
IUUC-Ola-086865	Oryzias latipes	33.50	1.00e-29	122.00
IUUC-Olu-087742	Ostreococcus lucimarinus	23.72	1.00e-11	62.40
IUUC-Oga-088527	Otolemur garnettii	28.57	7.00e-29	120.00
IUUC-Oar-089470	Ovis aries	28.61	6.00e-29	120.00
IUUC-Ptr-091086	Pan troglodytes	28.57	8.00e-29	120.00
IUUC-Pan-092236	Papio anubis	28.57	8.00e-29	120.00
IUUC-Psi-093900	Pelodiscus sinensis	27.74	3.00e-30	124.00
IUUC-Pma-094670	Petromyzon marinus	26.17	8.00e-29	119.00
IUUC-Pno-094862	Phaeosphaeria nodorum	35.03	1.00e-45	175.00
IUUC-Ppa-095583	Physcomitrella patens	30.04	3.00e-25	108.00
IUUC-Pfo-096704	Poecilia formosa	31.45	6.00e-32	129.00
IUUC-Pab-098400	Pongo abelii	28.89	8.00e-29	120.00
IUUC-Pop-099745	Populus trichocarpa	29.94	5.00e-17	81.30
IUUC-Pca-100372	Procavia capensis	25.95	1.00e-26	112.00
IUUC-Ppe-101666	Prunus persica	24.68	7.00e-20	90.90
IUUC-Pva-103134	Pteropus vampyrus	26.10	2.00e-26	112.00
IUUC-Pgr-103580	Puccinia graminis	29.59	7.00e-39	153.00
IUUC-Ptt-103870	Puccinia triticina	31.75	2.00e-37	147.00
IUUC-Pte-104331	Pyrenophora teres	30.07	9.00e-49	185.00
IUUC-Pyt-104673	Pyrenophora triticirepentis	28.18	1.00e-43	169.00
IUUC-Rno-105980	Rattus norvegicus	28.30	6.00e-29	120.00
IUUC-Sce-106333	Saccharomyces cerevisiae	34.20	1.00e-40	159.00
IUUC-Sha-107250	Sarcophilus harrisii	28.28	8.00e-27	113.00
IUUC-Sja-107662	Schizosaccharomyces japonicus	56.35	4.00e-151	526.00
IUUC-Ssl-108401	Sclerotinia sclerotiorum	24.04	3.00e-11	62.40
IUUC-Smo-109174	Selaginella moellendorffii	23.74	3.00e-14	72.00
IUUC-Sit-110527	Setaria italica	29.09	8.00e-24	103.00
IUUC-Sly-111180	Solanum lycopersicum	24.71	8.00e-22	97.40
IUUC-Stu-112120	Solanum tuberosum	30.60	3.00e-17	81.30
IUUC-Sar-113126	Sorex araneus	28.61	9.00e-29	119.00
IUUC-Sbi-114542	Sorghum bicolor	25.73	2.00e-18	85.50
IUUC-Sre-115069	Sporisorium reilianum	34.02	2.00e-43	169.00
IUUC-Ssc-115394	Sus scrofa	28.57	4.00e-28	117.00
IUUC-Tgu-116644	Taeniopygia guttata	27.78	9.00e-27	113.00
IUUC-Tru-118031	Takifugu rubripes	34.17	1.00e-30	125.00
IUUC-Tsy-119069	Tarsius syrichta	27.75	1.00e-26	112.00
IUUC-Tni-119766	Tetraodon nigroviridis	34.17	8.00e-31	126.00
IUUC-Tca-121811	Theobroma cacao	28.57	4.00e-21	95.10
IUUC-Tre-122003	Trichoderma reesei	29.59	1.00e-49	189.00
IUUC-Tvi-122408	Trichoderma virens	31.88	4.00e-46	176.00
IUUC-Tae-124718	Triticum aestivum	28.27	2.00e-23	102.00
IUUC-Tur-126304	Triticum urartu	25.30	1.00e-18	86.70
IUUC-Tme-126880	Tuber melanosporum	32.26	5.00e-65	239.00
IUUC-Tbe-127942	Tupaia belangeri	33.53	1.00e-24	105.00
IUUC-Ttr-128556	Tursiops truncatus	31.66	8.00e-26	109.00
IUUC-Uma-129549	Ustilago maydis	35.23	2.00e-49	188.00
IUUC-Vda-129985	Verticillium dahliae	30.10	2.00e-48	184.00
IUUC-Vpa-130725	Vicugna pacos	27.17	1.00e-27	115.00
IUUC-Vvi-131480	Vitis vinifera	27.39	8.00e-24	103.00
IUUC-Xtr-132733	Xenopus tropicalis	23.08	2.00e-30	125.00
IUUC-Xma-133963	Xiphophorus maculatus	34.17	2.00e-30	124.00
IUUC-Yli-134583	Yarrowia lipolytica	27.14	4.00e-41	160.00
IUUC-Zma-135188	Zea mays	25.35	4.00e-19	88.20

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence