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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Mmu-063131
Ensembl Protein ID ENSMUSP00000035992.7
UniProt Accession Q8R0H9; Q3U2N1; GGA1_MOUSE
Genbank Protein ID BAC38058.1; BAE33109.1; AAH26802.1
Protein Name ADP-ribosylation factor-binding protein GGA1; Gamma-adaptin-related protein 1; Golgi-localized, gamma ear-containing, ARF-binding protein 1
Genbank Nucleotide ID AK080881; AK155195; BC026802
Gene Name Gga1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000033128.8 ENSMUST00000041587.7 ENSMUSP00000035992.7
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
AREsitemicroRNATRANSFACRepTar
RAID2
Protein-protein Interaction
IIDiRefIndexMentha
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusmUbiSiDa
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/Alpha-Helix/GAT 1.00e-51 175.4 171 297
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/Alpha-Helix/GAT
   S: 1    deeksklLerLlkskkPeDLreAnkLikelvkededkaekikkliseleevksnvkllnemlselspegeepednellqelyetckaar 89
           deeksk+L+rLlks++PeDLr+AnkLike+v+ed++++eki+k+++++eev++nvkll+em++++s++++++++++l++ely++c+++r
   Q: 171  DEEKSKMLARLLKSSHPEDLRAANKLIKEMVQEDQKRMEKISKRVNAIEEVNNNVKLLTEMVMSHSQGAASSSSEDLMKELYQRCERMR 259
           79*************************************************************************************** PP
   S: 90   pkllklieeeedndellaellkanDelnqvlnkykqlk 127
           p+l++l++++ednde+lae+l+anD+l+qv+n ykql+
   Q: 260  PTLFRLASDTEDNDEALAEILQANDNLTQVINLYKQLV 297
           ***********************************987 PP
   
Organism Mus musculus
Functional Description
(View)

Functional Description


     Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF-dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (AC-LL) motif (By similarity).
 Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF-dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (AC-LL) motif (By similarity).
Protein Sequence
(Fasta)
MEPAMEPETL EARINRATNP LNKELNWASI NSFCEQLNED FEGPPLATRL LAHKIQSPQE 60
WEAIQALTVL ETCMKSCGKR FHDEVGKFRF LNELIKVVSP KYLGSRTSEK VKSKILELLY 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-063131|UBD,GAT|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GAAACATGGC TCCGGAGCGT TGTCCCGGAA GCGGTCACGG GTCTCTGCGT GACGCTAACT 60
GAGTTAGAGC GGTCCCGCGG GGTTTCTATG GTGCCGCCCG CCACCCCCAG GCTCTCCTCT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-063131|UBD,GAT|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0007--Acetylation
KW-0181--Complete proteome
KW-0967--Endosome
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0597--Phosphoprotein
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0832--Ubl conjugation
Interpro

IPR008152--Clathrin_a/b/g-adaptin_app_Ig
IPR008153--Clathrin_g-adaptin_app
IPR013041--Coatomer/clathrin_app_Ig-like
IPR008942--ENTH_VHS
IPR004152--GAT_dom
IPR002014--VHS_dom
PROSITE

PS50180--GAE
PS50909--GAT
PS50179--VHS
Pfam

PF02883--Alpha_adaptinC2
PF03127--GAT
PF00790--VHS
SMART

SM00809--Alpha_adaptinC2
SM00288--VHS
Gene Ontology

GO:0030131--C:clathrin adaptor complex
GO:0010008--C:endosome membrane
GO:0005794--C:Golgi apparatus
GO:0043231--C:intracellular membrane-bounded organelle
GO:0016020--C:membrane
GO:0005654--C:nucleoplasm
GO:0006886--P:intracellular protein transport
GO:0045732--P:positive regulation of protein catabolic process
GO:1901998--P:toxin transport
GO:0016192--P:vesicle-mediated transport
KEGG mmu:106039
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001226 Ailuropoda melanoleuca 82.83 0.00e+00 956.00
IUUC-Apl-003932 Anas platyrhynchos 80.51 3.00e-150 525.00
IUUC-Aca-004431 Anolis carolinensis 84.79 1.00e-142 500.00
IUUC-Ago-007767 Ashbya gossypii 27.68 6.00e-17 82.40
IUUC-Acl-008243 Aspergillus clavatus 27.64 1.00e-19 91.30
IUUC-Afu-008869 Aspergillus fumigatus 28.29 5.00e-20 92.80
IUUC-Ang-009840 Aspergillus niger 26.01 8.00e-17 82.00
IUUC-Aor-010219 Aspergillus oryzae 28.78 6.00e-23 102.00
IUUC-Ate-010290 Aspergillus terreus 27.91 2.00e-16 81.30
IUUC-Ame-011684 Astyanax mexicanus 68.23 4.00e-138 485.00
IUUC-Bgr-012048 Blumeria graminis 27.04 7.00e-20 92.40
IUUC-Bta-012975 Bos taurus 89.97 0.00e+00 1030.00
IUUC-Bci-013954 Botrytis cinerea 26.56 1.00e-20 95.10
IUUC-Cja-019098 Callithrix jacchus 78.88 0.00e+00 879.00
IUUC-Cfa-020394 Canis familiaris 90.44 0.00e+00 1019.00
IUUC-Cpo-022352 Cavia porcellus 90.28 0.00e+00 1040.00
IUUC-Csa-024037 Chlorocebus sabaeus 90.77 0.00e+00 1011.00
IUUC-Cgl-026721 Colletotrichum gloeosporioides 25.75 2.00e-20 94.40
IUUC-Dre-027709 Danio rerio 64.31 0.00e+00 722.00
IUUC-Dno-029170 Dasypus novemcinctus 80.31 0.00e+00 882.00
IUUC-Dor-030638 Dipodomys ordii 87.71 0.00e+00 1023.00
IUUC-Dse-031293 Dothistroma septosporum 26.91 2.00e-18 87.80
IUUC-Dme-031654 Drosophila melanogaster 32.18 5.00e-38 152.00
IUUC-Eca-034275 Equus caballus 89.48 0.00e+00 1022.00
IUUC-Eeu-035068 Erinaceus europaeus 69.82 0.00e+00 796.00
IUUC-Fca-036278 Felis catus 95.67 4.00e-156 545.00
IUUC-Fal-036971 Ficedula albicollis 78.87 0.00e+00 878.00
IUUC-Fox-037776 Fusarium oxysporum 28.80 1.00e-19 91.30
IUUC-Fso-038382 Fusarium solani 28.05 3.00e-19 90.10
IUUC-Gmo-039301 Gadus morhua 55.14 1.00e-140 493.00
IUUC-Ggr-039779 Gaeumannomyces graminis 29.56 1.00e-17 85.10
IUUC-Gga-040880 Gallus gallus 75.11 0.00e+00 848.00
IUUC-Gac-041955 Gasterosteus aculeatus 61.88 0.00e+00 679.00
IUUC-Ggo-045652 Gorilla gorilla 88.26 0.00e+00 990.00
IUUC-Hsa-045919 Homo sapiens 90.61 0.00e+00 1004.00
IUUC-Itr-048105 Ictidomys tridecemlineatus 89.52 0.00e+00 1067.00
IUUC-Kpa-049359 Komagataella pastoris 25.45 6.00e-17 82.40
IUUC-Lch-049488 Latimeria chalumnae 66.56 0.00e+00 743.00
IUUC-Laf-053697 Loxodonta africana 86.99 0.00e+00 981.00
IUUC-Mcc-054687 Macaca mulatta 86.61 0.00e+00 923.00
IUUC-Meu-056352 Macropus eugenii 72.11 0.00e+00 785.00
IUUC-Mor-057096 Magnaporthe oryzae 28.28 1.00e-16 81.60
IUUC-Mpo-057584 Magnaporthe poae 28.30 2.00e-09 57.40
IUUC-Mga-059936 Meleagris gallopavo 79.34 0.00e+00 890.00
IUUC-Mmr-060805 Microcebus murinus 84.56 0.00e+00 964.00
IUUC-Mdo-061808 Monodelphis domestica 76.28 0.00e+00 846.00
IUUC-Mpu-066602 Mustela putorius furo 87.19 0.00e+00 1018.00
IUUC-Mlu-068220 Myotis lucifugus 87.60 0.00e+00 968.00
IUUC-Nfi-068497 Neosartorya fischeri 28.73 2.00e-19 91.30
IUUC-Ncr-068625 Neurospora crassa 27.73 6.00e-19 89.40
IUUC-Nle-069039 Nomascus leucogenys 88.26 0.00e+00 988.00
IUUC-Opr-070709 Ochotona princeps 83.26 0.00e+00 974.00
IUUC-Ont-072069 Oreochromis niloticus 60.98 0.00e+00 697.00
IUUC-Oan-072906 Ornithorhynchus anatinus 71.04 0.00e+00 773.00
IUUC-Ola-086728 Oryzias latipes 56.30 0.00e+00 648.00
IUUC-Oga-088189 Otolemur garnettii 80.76 0.00e+00 910.00
IUUC-Oar-089226 Ovis aries 87.15 0.00e+00 994.00
IUUC-Pan-092529 Papio anubis 90.92 0.00e+00 1014.00
IUUC-Psi-093412 Pelodiscus sinensis 77.35 2.00e-162 566.00
IUUC-Pno-094904 Phaeosphaeria nodorum 30.43 8.00e-12 64.30
IUUC-Pfo-096458 Poecilia formosa 61.64 0.00e+00 706.00
IUUC-Pab-097684 Pongo abelii 89.20 0.00e+00 947.00
IUUC-Pca-100546 Procavia capensis 83.75 0.00e+00 751.00
IUUC-Pva-102877 Pteropus vampyrus 81.80 0.00e+00 944.00
IUUC-Rno-104917 Rattus norvegicus 95.91 0.00e+00 924.00
IUUC-Sha-107248 Sarcophilus harrisii 81.12 6.00e-141 494.00
IUUC-Ssc-115539 Sus scrofa 82.58 1.00e-118 419.00
IUUC-Tgu-117227 Taeniopygia guttata 78.25 0.00e+00 876.00
IUUC-Tru-118666 Takifugu rubripes 58.80 0.00e+00 691.00
IUUC-Tni-120663 Tetraodon nigroviridis 60.98 0.00e+00 659.00
IUUC-Tre-121890 Trichoderma reesei 28.37 1.00e-18 87.80
IUUC-Tbe-127589 Tupaia belangeri 87.31 0.00e+00 955.00
IUUC-Ttr-128616 Tursiops truncatus 87.61 0.00e+00 1040.00
IUUC-Vda-129948 Verticillium dahliae 27.24 9.00e-17 82.00
IUUC-Xtr-132596 Xenopus tropicalis 63.59 3.00e-152 531.00
IUUC-Xma-133092 Xiphophorus maculatus 58.91 0.00e+00 685.00
IUUC-Yli-134564 Yarrowia lipolytica 25.66 2.00e-17 84.00
Created Date 25-Jun-2017

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