iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMUSG00000025142.17	ENSMUST00000026135.14	ENSMUSP00000026135.8
ENSMUSG00000025142.17	ENSMUST00000168097.7	ENSMUSP00000130303.1
ENSMUSG00000025142.17	ENSMUST00000168714.7	ENSMUSP00000129462.1
ENSMUSG00000025142.17	ENSMUST00000143844.8	ENSMUSP00000129320.1
ENSMUSG00000025142.17	ENSMUST00000149389.7	ENSMUSP00000122216.1
ENSMUSG00000025142.17	ENSMUST00000106160.8	ENSMUSP00000101766.2
ENSMUSG00000025142.17	ENSMUST00000168510.1	ENSMUSP00000125931.1
ENSMUSG00000025142.17	ENSMUST00000166838.7	ENSMUSP00000127202.1
ENSMUSG00000025142.17	ENSMUST00000167678.1	ENSMUSP00000128940.1
ENSMUSG00000025142.17	ENSMUST00000168947.1	ENSMUSP00000125851.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	GXD
DNA & RNA Element
miRTarBase	microRNA	TRANSFAC	RepTar
RAID2
Protein-protein Interaction
IID
Protein 3D Structure
PDB	MMDB
Post-translational Modifications (PTMs)
CPLM	dbPAF	PhosphositePlus	dbPTM
UniProt	PHOSIDA	mUbiSiDa
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
ULD/UDP/UFD/UBX	1.30e-10	42.8	383	456

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

ULD/UDP/UFD/UBX

   S: 2    tteqatlqiRlpdGkrlvrkFpssttleqiyqfveyllvessdpFeLvspfPrrtlkpeehmstlqeagLvpsgsl 77
           +++++ l++ +pd  +l+  F++s+t+ ++++fv   l++++  F L+ + P+  l++ +   tl +a+L+p + +
   Q: 383  RYPKVALRVLFPDRYILQGFFRPSETVGDLRDFVRSHLGNPELSFYLFIAPPKMVLDDHTL--TLFQANLFPAALV 456
           56789999*****************************************************..*********9987 PP

Organism

Mus musculus

Functional Description
(View)

Enhances VCP methylation catalyzed by VCPKMT (By similarity). Tethering protein that sequesters GLUT4-containing vesicles in the cytoplasm in the absence of insulin. Modulates the amount of GLUT4 that is available at the cell surface.

Protein Sequence
(Fasta)

MAAPAGGGGS AVSVLAPNGR RHTVKVTPST VLLQVLEDTC RRQDFNPSEY DLKFQRTVLD 60
LSLQWRFANL PNNAKLEMVP VSRSREGPEN IVRIAFQLDD GSRLQDAFCS RQTLWELLSH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGTTGGCCC CGCCCCCGAG ACCGCGTGGC TGTGCGTCCG GGCTGTTGCG GATAAAGTTG 60
TTTGAGGCGA GCCGGCTGCG GTCACGTGAG CGGAAGATGG CGGCCCCGGC GGGCGGCGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0002--3D-structure
KW-0007--Acetylation
KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0472--Membrane
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome

Interpro

IPR021569--TUG-UBL1
IPR029071--Ubiquitin-rel_dom
IPR001012--UBX_dom

PROSITE

PS50033--UBX

Pfam

PF11470--TUG-UBL1
PF00789--UBX

Gene Ontology

GO:0009898--C:cytoplasmic side of plasma membrane
GO:0030659--C:cytoplasmic vesicle membrane
GO:0005829--C:cytosol
GO:0012505--C:endomembrane system
GO:0033116--C:endoplasmic reticulum-Golgi intermediate compartment membrane
GO:0019898--C:extrinsic component of membrane
GO:0043231--C:intracellular membrane-bounded organelle
GO:0005654--C:nucleoplasm
GO:0048471--C:perinuclear region of cytoplasm
GO:0005886--C:plasma membrane
GO:0012506--C:vesicle membrane
GO:0042593--P:glucose homeostasis
GO:0006886--P:intracellular protein transport
GO:0061024--P:membrane organization
GO:0046324--P:regulation of glucose import

KEGG

mmu:68938

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000698	Aegilops tauschii	32.82	8.00e-12	64.30
IUUC-Aml-001972	Ailuropoda melanoleuca	69.98	0.00e+00	655.00
IUUC-Atr-002652	Amborella trichopoda	31.82	5.00e-13	67.80
IUUC-Apl-003798	Anas platyrhynchos	56.44	1.00e-121	429.00
IUUC-Aca-004974	Anolis carolinensis	51.96	2.00e-123	436.00
IUUC-Aly-005873	Arabidopsis lyrata	31.61	1.00e-15	77.00
IUUC-Ath-007011	Arabidopsis thaliana	29.05	1.00e-16	79.70
IUUC-Ago-007968	Ashbya gossypii	24.76	1.00e-06	47.80
IUUC-Ang-009752	Aspergillus niger	32.46	3.00e-16	80.10
IUUC-Ame-011408	Astyanax mexicanus	65.50	1.00e-61	230.00
IUUC-Bgr-012185	Blumeria graminis	27.76	3.00e-13	69.70
IUUC-Bta-013229	Bos taurus	63.15	3.00e-167	581.00
IUUC-Bci-013663	Botrytis cinerea	31.77	1.00e-13	71.20
IUUC-Bdi-014106	Brachypodium distachyon	33.59	9.00e-15	73.90
IUUC-Bol-016462	Brassica oleracea	33.77	1.00e-14	73.20
IUUC-Bra-016945	Brassica rapa	36.43	9.00e-15	73.60
IUUC-Cja-018972	Callithrix jacchus	67.48	2.00e-150	526.00
IUUC-Cfa-020042	Canis familiaris	76.58	0.00e+00	731.00
IUUC-Cpo-022330	Cavia porcellus	76.29	0.00e+00	710.00
IUUC-Csa-023061	Chlorocebus sabaeus	83.83	3.00e-106	379.00
IUUC-Cin-025714	Ciona intestinalis	44.51	1.00e-34	140.00
IUUC-Csv-025969	Ciona savignyi	39.33	4.00e-28	118.00
IUUC-Cgl-026566	Colletotrichum gloeosporioides	27.98	2.00e-12	67.40
IUUC-Cme-027320	Cyanidioschyzon merolae	29.60	5.00e-09	56.20
IUUC-Dre-027590	Danio rerio	50.53	5.00e-45	173.00
IUUC-Dno-030001	Dasypus novemcinctus	71.31	2.00e-87	315.00
IUUC-Dor-030212	Dipodomys ordii	80.59	6.00e-86	311.00
IUUC-Dse-031476	Dothistroma septosporum	29.10	1.00e-12	67.80
IUUC-Dme-032123	Drosophila melanogaster	37.02	3.00e-29	123.00
IUUC-Eca-033956	Equus caballus	75.00	2.00e-176	612.00
IUUC-Eeu-034437	Erinaceus europaeus	70.52	3.00e-146	511.00
IUUC-Fca-036486	Felis catus	82.28	3.00e-101	362.00
IUUC-Fal-037419	Ficedula albicollis	50.73	3.00e-98	352.00
IUUC-Fox-037927	Fusarium oxysporum	29.90	4.00e-13	69.70
IUUC-Fso-038161	Fusarium solani	30.41	5.00e-13	69.30
IUUC-Gmo-039169	Gadus morhua	58.33	2.00e-53	202.00
IUUC-Ggr-040027	Gaeumannomyces graminis	37.61	5.00e-13	69.30
IUUC-Gga-040858	Gallus gallus	53.74	2.00e-128	452.00
IUUC-Gac-042005	Gasterosteus aculeatus	47.22	7.00e-52	198.00
IUUC-Gma-043203	Glycine max	31.94	2.00e-19	89.70
IUUC-Hsa-046613	Homo sapiens	72.43	7.00e-77	281.00
IUUC-Itr-049012	Ictidomys tridecemlineatus	77.65	0.00e+00	696.00
IUUC-Kpa-049336	Komagataella pastoris	42.37	7.00e-06	45.40
IUUC-Lch-050340	Latimeria chalumnae	47.05	8.00e-125	441.00
IUUC-Lpe-050814	Leersia perrieri	32.85	4.00e-16	78.60
IUUC-Loc-052372	Lepisosteus oculatus	52.59	3.00e-65	243.00
IUUC-Lma-053308	Leptosphaeria maculans	32.07	6.00e-14	72.40
IUUC-Mcc-055837	Macaca mulatta	78.79	5.00e-90	325.00
IUUC-Meu-056520	Macropus eugenii	59.78	3.00e-59	223.00
IUUC-Mor-057043	Magnaporthe oryzae	36.84	6.00e-13	68.90
IUUC-Mpo-057330	Magnaporthe poae	38.46	2.00e-13	70.90
IUUC-Mtr-058132	Medicago truncatula	32.00	5.00e-14	70.90
IUUC-Mla-058858	Melampsora laricipopulina	29.63	9.00e-10	57.40
IUUC-Mvi-060506	Microbotryum violaceum	26.85	2.00e-06	46.60
IUUC-Mmr-060594	Microcebus murinus	78.94	0.00e+00	679.00
IUUC-Mdo-063086	Monodelphis domestica	66.99	4.00e-129	454.00
IUUC-Mac-065305	Musa acuminata	35.33	2.00e-17	82.80
IUUC-Mpu-066836	Mustela putorius furo	75.69	3.00e-167	581.00
IUUC-Mlu-067180	Myotis lucifugus	70.91	4.00e-142	497.00
IUUC-Ncr-068683	Neurospora crassa	30.05	2.00e-16	80.90
IUUC-Opr-070793	Ochotona princeps	64.99	6.00e-129	454.00
IUUC-Ont-071540	Oreochromis niloticus	54.69	2.00e-66	246.00
IUUC-Oba-074998	Oryza barthii	34.35	3.00e-17	82.40
IUUC-Obr-076489	Oryza brachyantha	33.59	1.00e-16	80.50
IUUC-Ogl-077919	Oryza glaberrima	34.35	3.00e-17	82.00
IUUC-Ogu-078747	Oryza glumaepatula	35.77	3.00e-17	82.40
IUUC-Oin-080147	Oryza indica	34.35	3.00e-17	82.00
IUUC-Olo-080748	Oryza longistaminata	35.77	7.00e-17	82.80
IUUC-Oni-082994	Oryza nivara	35.77	3.00e-17	82.80
IUUC-Opu-083874	Oryza punctata	34.59	8.00e-16	77.80
IUUC-Oru-084505	Oryza rufipogon	35.77	3.00e-17	82.40
IUUC-Osa-085824	Oryza sativa	34.35	3.00e-17	82.00
IUUC-Ola-086735	Oryzias latipes	48.10	5.00e-50	192.00
IUUC-Olu-087905	Ostreococcus lucimarinus	32.69	9.00e-05	39.70
IUUC-Oga-088544	Otolemur garnettii	77.88	0.00e+00	689.00
IUUC-Oar-090181	Ovis aries	79.12	0.00e+00	649.00
IUUC-Ptr-090650	Pan troglodytes	88.32	9.00e-68	251.00
IUUC-Pan-092580	Papio anubis	85.23	1.00e-108	386.00
IUUC-Psi-093221	Pelodiscus sinensis	55.10	2.00e-135	476.00
IUUC-Pno-094973	Phaeosphaeria nodorum	25.42	9.00e-14	72.00
IUUC-Ppa-095975	Physcomitrella patens	34.00	5.00e-15	74.30
IUUC-Pfo-096866	Poecilia formosa	52.82	6.00e-66	245.00
IUUC-Pab-098495	Pongo abelii	84.72	8.00e-100	357.00
IUUC-Pop-099718	Populus trichocarpa	37.23	7.00e-15	73.90
IUUC-Ppe-101204	Prunus persica	35.92	6.00e-15	74.30
IUUC-Pva-103121	Pteropus vampyrus	67.03	2.00e-167	582.00
IUUC-Pgr-103386	Puccinia graminis	33.33	2.00e-08	52.80
IUUC-Pte-104201	Pyrenophora teres	29.26	9.00e-14	72.00
IUUC-Pyt-104667	Pyrenophora triticirepentis	28.57	7.00e-14	72.00
IUUC-Sce-106458	Saccharomyces cerevisiae	24.77	5.00e-05	42.40
IUUC-Sha-107534	Sarcophilus harrisii	71.38	0.00e+00	676.00
IUUC-Smo-109357	Selaginella moellendorffii	30.81	4.00e-17	81.30
IUUC-Sit-110104	Setaria italica	34.35	2.00e-17	82.80
IUUC-Sly-111163	Solanum lycopersicum	39.74	7.00e-14	70.90
IUUC-Sbi-114807	Sorghum bicolor	33.59	2.00e-16	79.70
IUUC-Tgu-117269	Taeniopygia guttata	55.14	6.00e-124	437.00
IUUC-Tru-117641	Takifugu rubripes	53.63	8.00e-64	238.00
IUUC-Tni-120606	Tetraodon nigroviridis	60.75	9.00e-60	224.00
IUUC-Tca-121549	Theobroma cacao	29.58	3.00e-19	88.60
IUUC-Tre-122242	Trichoderma reesei	30.93	4.00e-15	76.30
IUUC-Tvi-122604	Trichoderma virens	30.93	3.00e-14	73.20
IUUC-Tae-124738	Triticum aestivum	33.59	2.00e-12	66.20
IUUC-Tur-126645	Triticum urartu	30.94	4.00e-12	65.10
IUUC-Tme-126884	Tuber melanosporum	28.49	2.00e-12	67.00
IUUC-Ttr-129059	Tursiops truncatus	75.55	4.00e-89	322.00
IUUC-Vda-129931	Verticillium dahliae	31.98	5.00e-15	75.90
IUUC-Vvi-131634	Vitis vinifera	35.61	8.00e-20	90.10
IUUC-Xtr-132692	Xenopus tropicalis	48.95	3.00e-105	375.00
IUUC-Xma-133296	Xiphophorus maculatus	53.63	9.00e-66	244.00
IUUC-Yli-134611	Yarrowia lipolytica	28.18	1.00e-06	47.80

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence