iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMUSG00000059866.13	ENSMUST00000030991.13	ENSMUSP00000030991.7
ENSMUSG00000059866.13	ENSMUST00000087737.9	ENSMUSP00000085030.3
ENSMUSG00000059866.13	ENSMUST00000114359.1	ENSMUSP00000109999.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	GXD
DNA & RNA Element
AREsite	microRNA	TRANSFAC	RepTar
RAID2
Post-translational Modifications (PTMs)
PHOSIDA	BioGRID
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBAN	2.50e-19	70.1	311	367

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBAN

   S: 1    keelletvevLkqQveiYkeDFqaERadRErlneekeeLqeqveklqkqvsklndsl 57
           ++ +le+v++L+qQ+ +Yk+DF++ERadREr++++++eL+e++ +l  qvs+++ds+
   Q: 311  RDTALERVQMLEQQILAYKDDFKSERADRERAHSRIQELEEKIMSLMYQVSQRQDSR 367
           6789***************************************************97 PP

Organism

Mus musculus

Protein Sequence
(Fasta)

MSSGDPRSGR QDGAPRAAAA LCGLYHEAGQ QLQRLKDQLA ARDALIASLR TRLAALEGHT 60
APSLVDALLD QVERFREQLR RQEEGASETQ LRQEVERLTE RLEEKEREMQ QLMSQPQHEQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGCGGGGCG GGAAACGTTC CGGGAAGGCT GGTTTTCGCT CCCCCTGTGT GGAGAAGTTG 60
GAGACGCCCA AGTCCCCACG GAAGGCCTAC AGCCATGTCG TCTGGGGACC CAAGGTCTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR032419--CC2-LZ_dom
IPR022008--EABR
IPR034735--ZF_CCHC_NOA

PROSITE

PS51801--ZF_CCHC_NOA

Pfam

PF16516--CC2-LZ
PF12180--EABR

Gene Ontology

GO:0005737--C:cytoplasm
GO:0023035--P:CD40 signaling pathway
GO:0071222--P:cellular response to lipopolysaccharide
GO:0007249--P:I-kappaB kinase/NF-kappaB signaling
GO:0070498--P:interleukin-1-mediated signaling pathway
GO:0050871--P:positive regulation of B cell activation
GO:0043032--P:positive regulation of macrophage activation
GO:0050821--P:protein stabilization
GO:0034134--P:toll-like receptor 2 signaling pathway
GO:0034138--P:toll-like receptor 3 signaling pathway
GO:0034162--P:toll-like receptor 9 signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001697	Ailuropoda melanoleuca	71.59	1.00e-135	476.00
IUUC-Apl-003896	Anas platyrhynchos	47.83	2.00e-96	345.00
IUUC-Ame-011223	Astyanax mexicanus	31.50	4.00e-44	172.00
IUUC-Bta-012996	Bos taurus	70.11	4.00e-129	454.00
IUUC-Cja-019376	Callithrix jacchus	70.64	1.00e-136	479.00
IUUC-Cfa-021027	Canis familiaris	67.73	3.00e-150	524.00
IUUC-Cpo-021372	Cavia porcellus	61.86	2.00e-111	395.00
IUUC-Csa-023221	Chlorocebus sabaeus	74.61	2.00e-156	545.00
IUUC-Dre-028604	Danio rerio	32.40	2.00e-52	199.00
IUUC-Dno-029976	Dasypus novemcinctus	59.55	9.00e-50	189.00
IUUC-Dor-030364	Dipodomys ordii	56.90	6.00e-61	228.00
IUUC-Eca-033582	Equus caballus	71.21	6.00e-143	500.00
IUUC-Eeu-034751	Erinaceus europaeus	60.85	9.00e-58	216.00
IUUC-Fca-036086	Felis catus	67.95	2.00e-122	431.00
IUUC-Fal-036828	Ficedula albicollis	46.60	4.00e-98	351.00
IUUC-Gmo-038838	Gadus morhua	34.94	6.00e-47	181.00
IUUC-Gga-041179	Gallus gallus	44.89	4.00e-93	335.00
IUUC-Gac-042266	Gasterosteus aculeatus	37.02	4.00e-47	182.00
IUUC-Ggo-044971	Gorilla gorilla	75.50	1.00e-157	549.00
IUUC-Hsa-045772	Homo sapiens	75.50	3.00e-149	521.00
IUUC-Itr-048993	Ictidomys tridecemlineatus	71.51	4.00e-129	454.00
IUUC-Lch-049851	Latimeria chalumnae	38.95	1.00e-70	260.00
IUUC-Loc-052551	Lepisosteus oculatus	36.81	2.00e-65	243.00
IUUC-Laf-053650	Loxodonta africana	57.63	3.00e-89	321.00
IUUC-Mcc-054744	Macaca mulatta	75.06	5.00e-161	560.00
IUUC-Meu-056799	Macropus eugenii	51.02	6.00e-32	131.00
IUUC-Mga-060124	Meleagris gallopavo	43.78	4.00e-88	318.00
IUUC-Mmr-061466	Microcebus murinus	74.61	9.00e-146	509.00
IUUC-Mdo-062389	Monodelphis domestica	56.28	2.00e-117	416.00
IUUC-Mpu-066109	Mustela putorius furo	69.46	5.00e-152	530.00
IUUC-Mlu-067666	Myotis lucifugus	62.34	5.00e-71	260.00
IUUC-Nle-069689	Nomascus leucogenys	73.37	3.00e-138	484.00
IUUC-Opr-070774	Ochotona princeps	53.39	7.00e-76	277.00
IUUC-Ont-072439	Oreochromis niloticus	34.13	2.00e-58	220.00
IUUC-Oan-072817	Ornithorhynchus anatinus	51.82	4.00e-59	221.00
IUUC-Ocu-074621	Oryctolagus cuniculus	61.54	8.00e-85	306.00
IUUC-Ola-087305	Oryzias latipes	35.64	6.00e-55	208.00
IUUC-Oga-087920	Otolemur garnettii	71.08	9.00e-145	506.00
IUUC-Oar-090351	Ovis aries	66.32	7.00e-20	88.20
IUUC-Ptr-090879	Pan troglodytes	78.24	4.00e-99	354.00
IUUC-Pan-092022	Papio anubis	74.83	7.00e-157	546.00
IUUC-Psi-093302	Pelodiscus sinensis	44.68	2.00e-102	365.00
IUUC-Pno-095083	Phaeosphaeria nodorum	26.79	1.30e-01	32.70
IUUC-Pfo-097250	Poecilia formosa	34.61	1.00e-52	200.00
IUUC-Pab-097929	Pongo abelii	74.05	9.00e-143	499.00
IUUC-Pca-100271	Procavia capensis	67.11	5.00e-45	174.00
IUUC-Pva-102234	Pteropus vampyrus	63.19	2.00e-112	399.00
IUUC-Pte-104050	Pyrenophora teres	29.85	2.40e-01	32.00
IUUC-Rno-105850	Rattus norvegicus	89.58	0.00e+00	764.00
IUUC-Sha-107375	Sarcophilus harrisii	54.20	7.00e-107	380.00
IUUC-Ssc-116269	Sus scrofa	70.02	2.00e-140	492.00
IUUC-Tgu-116960	Taeniopygia guttata	48.51	1.00e-93	336.00
IUUC-Tru-118002	Takifugu rubripes	32.61	6.00e-53	201.00
IUUC-Tni-120023	Tetraodon nigroviridis	35.09	1.00e-53	203.00
IUUC-Tbe-127592	Tupaia belangeri	65.65	7.00e-140	490.00
IUUC-Ttr-128362	Tursiops truncatus	65.08	1.00e-114	406.00
IUUC-Vpa-130399	Vicugna pacos	64.80	2.00e-114	405.00
IUUC-Xtr-132677	Xenopus tropicalis	44.18	1.00e-81	296.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence