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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Cel-018150
UUCD1 version UUC-CaE-00532
Ensembl Protein ID Y48G8AL.1a
UniProt Accession Q9BL11; Q9BL11_CAEEL
Genbank Protein ID CCD73459.1
Protein Name HECT and RCC domain E3 ubiquitin ligase
Genbank Nucleotide ID BX284601
Gene Name herc-1; CELE_Y48G8AL.1; Y48G8AL.1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
WBGene00021685 Y48G8AL.1a Y48G8AL.1a
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
microRNARAID2
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/HECT 1.10e-82 278.4 689 1018
Active Site
Position(s) Description Evidence
987 Glycyl thioester intermediate {ECO:0000256|PROSITE-ProRule:PRU00104}
Domain Profile

   E3 activity/HECT
   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlplsksfyk 98
           +sdl+k l+v+ +gE++ d+gGv +ef+ l+++++ ++d+g+f  +e+++  ++    s ++     + F+ lGrl+g++++++ +++ p++ ++yk
   Q: 689  ESDLQKPLKVNIAGEDADDAGGVRKEFFILVMRKILQSDYGMFSEDEESHLVWFSGLPSEFC---DREQFHQLGRLVGLSIYNHSIVPFPFPLALYK 782
           789*****************************************************999985...6899**************************** PP
   S: 99   lllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvveyrlke....gikeqve 191
            ll+++ +ledl e+ p   k lk +++++e+d+e+  + l+f++s +ilget+++eL++gG + pVtn+N++eYv+l+v++rl+     +i++q  
   Q: 783  YLLDTPPDLEDLCELSPSEGKGLKMLLSYEEDDVEDV-FGLNFCISFNILGETHTTELLSGGTEKPVTNANRDEYVRLYVHHRLELgyngEIAQQAL 878
           *****************************99999998.**********************************************752223799**** PP
   S: 192  afreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvTgssrlPlgGfaelkprlfv 288
            fr+Gf+e +  + l+ F++ el+ +i G+e++d++++++  +y+g+y++++p+iq Fw+++ +++++er++fLqF+Tgs r+P+ G +el+     
   Q: 879  LFRKGFSESLHSRTLRFFQPCELKEMIVGNENYDWNEFRDILMYRGEYSSSHPTIQAFWKAFFALTDDERRKFLQFLTGSTRIPVSGWEELH---AA 972
           ********************************************************************************************...67 PP
   S: 289  irkdasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFel 335
           i+  +++++lP ++TCfn+L+LP+     +l ++L++ ie+t+gF l
   Q: 973  IQP-SAPESLPVAHTCFNLLDLPNIADDVELLRRLRISIEHTEGFTL 1018
           887.899**************************************87 PP
   
Organism Caenorhabditis elegans
Protein Sequence
(Fasta)
MRAELLGCGH TGEGQLGVRL SESTIQVPER IIGAPNDMDG TAVTSVTCGE QHTVFLTKDG 60
KMWSVGSNMD GQLGRGSRTE GSFSIYPVSW TSSAKIIQIS AGRSHTVSVT DDGRVFAWGS 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Cel-018150|E3,HECT|Caenorhabditis elegans
Please wait for a moment...
Nucleotide Sequence
(Fasta)
AAAATGCGAG CTGAGCTGCT CGGATGTGGA CACACGGGCG AGGGACAGCT CGGCGTTCGG 60
CTCTCCGAGT CGACGATTCA AGTTCCCGAG AGAATTAGTA CGGAGCTATT TTTGTTGCAG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Cel-018150|E3,HECT|Caenorhabditis elegans
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0436--Ligase
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0833--Ubl conjugation pathway
Interpro

IPR000569--HECT_dom
IPR009091--RCC1/BLIP-II
IPR000408--Reg_chr_condens
PROSITE

PS50237--HECT
PS00626--RCC1_2
PS50012--RCC1_3
Pfam

PF00632--HECT
PF00415--RCC1
PRINTS

PR00633--RCCNDNSATION
SMART

SM00119--HECTc
Gene Ontology

GO:0016874--F:ligase activity
GO:0004842--F:ubiquitin-protein transferase activity
KEGG cel:CELE_Y48G8AL.1
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001673 Ailuropoda melanoleuca 32.93 1.00e-148 519.00
IUUC-Atr-003144 Amborella trichopoda 33.26 4.00e-61 227.00
IUUC-Apl-003535 Anas platyrhynchos 34.17 3.00e-151 528.00
IUUC-Aca-004336 Anolis carolinensis 33.79 9.00e-149 520.00
IUUC-Ago-007908 Ashbya gossypii 31.97 7.00e-51 194.00
IUUC-Acl-008288 Aspergillus clavatus 31.32 2.00e-50 193.00
IUUC-Afl-008402 Aspergillus flavus 30.45 1.00e-46 180.00
IUUC-Afu-008762 Aspergillus fumigatus 30.98 9.00e-52 197.00
IUUC-Ani-009176 Aspergillus nidulans 31.21 4.00e-52 198.00
IUUC-Ang-009791 Aspergillus niger 31.03 2.00e-51 196.00
IUUC-Aor-009921 Aspergillus oryzae 30.67 5.00e-47 181.00
IUUC-Ate-010295 Aspergillus terreus 31.32 5.00e-54 205.00
IUUC-Ame-010768 Astyanax mexicanus 34.45 8.00e-155 540.00
IUUC-Bgr-011981 Blumeria graminis 29.85 3.00e-49 189.00
IUUC-Bta-013373 Bos taurus 33.02 6.00e-150 523.00
IUUC-Bci-013697 Botrytis cinerea 32.96 2.00e-44 173.00
IUUC-Cja-019609 Callithrix jacchus 33.30 9.00e-150 523.00
IUUC-Cfa-021071 Canis familiaris 33.12 3.00e-149 521.00
IUUC-Cpo-021548 Cavia porcellus 33.30 2.00e-148 519.00
IUUC-Cre-022790 Chlamydomonas reinhardtii 35.20 5.00e-46 176.00
IUUC-Csa-023987 Chlorocebus sabaeus 33.21 1.00e-149 522.00
IUUC-Cho-024325 Choloepus hoffmanni 34.48 5.00e-89 321.00
IUUC-Cin-025232 Ciona intestinalis 31.31 7.00e-137 480.00
IUUC-Csv-026282 Ciona savignyi 34.87 5.00e-53 201.00
IUUC-Cgl-026526 Colletotrichum gloeosporioides 31.14 7.00e-52 198.00
IUUC-Cme-027151 Cyanidioschyzon merolae 35.70 3.00e-66 245.00
IUUC-Dre-027472 Danio rerio 33.92 2.00e-150 525.00
IUUC-Dno-029241 Dasypus novemcinctus 33.52 3.00e-151 528.00
IUUC-Dor-030158 Dipodomys ordii 40.87 2.00e-80 293.00
IUUC-Dse-031239 Dothistroma septosporum 28.83 2.00e-44 173.00
IUUC-Dme-032103 Drosophila melanogaster 33.82 6.00e-143 500.00
IUUC-Ete-032642 Echinops telfairi 32.07 9.00e-137 479.00
IUUC-Eca-033646 Equus caballus 32.84 7.00e-147 513.00
IUUC-Eeu-035098 Erinaceus europaeus 28.71 1.00e-70 260.00
IUUC-Fca-035682 Felis catus 35.05 4.00e-133 468.00
IUUC-Fal-036969 Ficedula albicollis 34.25 2.00e-146 511.00
IUUC-Fox-037941 Fusarium oxysporum 30.79 3.00e-56 212.00
IUUC-Fso-038388 Fusarium solani 30.49 9.00e-55 207.00
IUUC-Gmo-038671 Gadus morhua 33.89 2.00e-142 498.00
IUUC-Ggr-040110 Gaeumannomyces graminis 32.23 3.00e-55 209.00
IUUC-Gga-040591 Gallus gallus 34.14 3.00e-151 528.00
IUUC-Gac-042600 Gasterosteus aculeatus 33.33 3.00e-143 501.00
IUUC-Ggo-044769 Gorilla gorilla 33.36 3.00e-150 525.00
IUUC-Hsa-046066 Homo sapiens 33.21 2.00e-149 522.00
IUUC-Itr-048311 Ictidomys tridecemlineatus 33.59 2.00e-148 518.00
IUUC-Kpa-049152 Komagataella pastoris 31.86 1.00e-51 196.00
IUUC-Lch-050301 Latimeria chalumnae 34.02 6.00e-155 540.00
IUUC-Loc-052803 Lepisosteus oculatus 33.36 7.00e-148 516.00
IUUC-Lma-053245 Leptosphaeria maculans 33.07 3.00e-49 189.00
IUUC-Laf-053364 Loxodonta africana 33.09 4.00e-150 524.00
IUUC-Mcc-054930 Macaca mulatta 33.12 2.00e-149 522.00
IUUC-Meu-056061 Macropus eugenii 34.39 2.00e-61 229.00
IUUC-Mor-057045 Magnaporthe oryzae 29.33 1.00e-51 197.00
IUUC-Mga-059563 Meleagris gallopavo 34.26 5.00e-151 527.00
IUUC-Mmr-060792 Microcebus murinus 33.24 4.00e-150 524.00
IUUC-Mdo-062195 Monodelphis domestica 34.04 9.00e-149 520.00
IUUC-Mmu-063369 Mus musculus 34.56 4.00e-141 494.00
IUUC-Mpu-066308 Mustela putorius furo 33.02 3.00e-149 521.00
IUUC-Mlu-066927 Myotis lucifugus 33.12 1.00e-148 519.00
IUUC-Nfi-068439 Neosartorya fischeri 31.03 3.00e-51 196.00
IUUC-Ncr-068903 Neurospora crassa 31.99 1.00e-49 191.00
IUUC-Nle-070090 Nomascus leucogenys 33.27 3.00e-149 521.00
IUUC-Opr-070891 Ochotona princeps 30.60 1.00e-109 389.00
IUUC-Ont-071720 Oreochromis niloticus 34.78 5.00e-140 491.00
IUUC-Oan-073464 Ornithorhynchus anatinus 35.03 8.00e-128 450.00
IUUC-Ocu-074770 Oryctolagus cuniculus 33.21 3.00e-149 521.00
IUUC-Ola-086550 Oryzias latipes 33.95 7.00e-156 543.00
IUUC-Oga-088831 Otolemur garnettii 33.02 4.00e-148 517.00
IUUC-Oar-090449 Ovis aries 32.84 4.00e-149 521.00
IUUC-Ptr-091368 Pan troglodytes 35.01 1.00e-136 479.00
IUUC-Pan-092135 Papio anubis 33.27 5.00e-150 523.00
IUUC-Psi-093832 Pelodiscus sinensis 33.12 3.00e-154 538.00
IUUC-Pma-094113 Petromyzon marinus 34.98 3.00e-107 381.00
IUUC-Pno-094886 Phaeosphaeria nodorum 30.79 1.00e-45 177.00
IUUC-Ppa-095354 Physcomitrella patens 34.55 6.00e-65 241.00
IUUC-Pfo-097021 Poecilia formosa 34.86 6.00e-155 540.00
IUUC-Pab-098249 Pongo abelii 33.21 1.00e-149 523.00
IUUC-Pca-100320 Procavia capensis 30.02 1.00e-109 389.00
IUUC-Pva-102506 Pteropus vampyrus 32.05 3.00e-118 418.00
IUUC-Pgr-103315 Puccinia graminis 31.07 4.00e-53 201.00
IUUC-Ptt-103736 Puccinia triticina 30.97 9.00e-58 217.00
IUUC-Pte-104055 Pyrenophora teres 32.03 1.00e-46 180.00
IUUC-Pyt-104647 Pyrenophora triticirepentis 32.02 7.00e-46 178.00
IUUC-Rno-105457 Rattus norvegicus 34.34 2.00e-140 492.00
IUUC-Sce-106306 Saccharomyces cerevisiae 28.74 2.00e-43 169.00
IUUC-Sha-106632 Sarcophilus harrisii 33.89 1.00e-140 492.00
IUUC-Spo-108271 Schizosaccharomyces pombe 30.37 2.00e-49 189.00
IUUC-Ssl-108657 Sclerotinia sclerotiorum 29.87 1.00e-47 184.00
IUUC-Smo-108858 Selaginella moellendorffii 33.53 1.00e-68 253.00
IUUC-Stu-112166 Solanum tuberosum 26.60 4.00e-23 102.00
IUUC-Sar-113679 Sorex araneus 29.76 8.00e-50 191.00
IUUC-Ssc-115473 Sus scrofa 32.93 6.00e-149 520.00
IUUC-Tgu-116974 Taeniopygia guttata 34.04 5.00e-148 517.00
IUUC-Tru-118206 Takifugu rubripes 33.27 3.00e-131 461.00
IUUC-Tsy-119619 Tarsius syrichta 28.75 4.00e-75 275.00
IUUC-Tni-120233 Tetraodon nigroviridis 34.11 8.00e-135 473.00
IUUC-Tre-122108 Trichoderma reesei 32.96 9.00e-48 184.00
IUUC-Tvi-122644 Trichoderma virens 32.96 2.00e-48 186.00
IUUC-Tme-127004 Tuber melanosporum 32.31 6.00e-50 192.00
IUUC-Tbe-127640 Tupaia belangeri 32.46 1.00e-143 502.00
IUUC-Ttr-129172 Tursiops truncatus 32.90 2.00e-146 511.00
IUUC-Vda-129969 Verticillium dahliae 31.03 4.00e-54 206.00
IUUC-Vpa-130448 Vicugna pacos 34.41 1.00e-132 466.00
IUUC-Xtr-132194 Xenopus tropicalis 31.36 4.00e-118 418.00
IUUC-Xma-133389 Xiphophorus maculatus 34.81 1.00e-153 536.00
IUUC-Yli-134470 Yarrowia lipolytica 29.19 2.00e-42 166.00
Created Date 25-Jun-2017

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