iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID	iRefIndex	PINA
Protein 3D Structure
PDB
Post-translational Modifications (PTMs)
dbPAF	PHOSIDA
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
ULD/UBL/SUMO	4.40e-29	101.1	11	88

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

ULD/UBL/SUMO

   S: 7    apvslkvagqdGsevlfklklsaqlkklmeavYvkrinldensvrfvfngqkireqetpeelevededkiellcqksGG 85
           ++++lkv gqd + v+fk+k++++l+klm+a Y++r +l+++ vrf+f+gq+i+e++tp  le+e++d+ie+++q++GG
   Q: 11   EHINLKVLGQDNAVVQFKIKKHTPLRKLMNA-YCDRAGLSMQVVRFRFDGQPINENDTPTSLEMEEGDTIEVYQQQTGG 88
           79*****************************.**********************************************9 PP

Organism

Drosophila melanogaster

Protein Sequence
(Fasta)

MSDEKKGGET EHINLKVLGQ DNAVVQFKIK KHTPLRKLMN AYCDRAGLSM QVVRFRFDGQ 60
PINENDTPTS LEMEEGDTIE VYQQQTGGAP

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CACCGATAGT ATCGCAAAAG TTAACGAGGT AGGTCCAGCA CCAGTTTTTT TGGCGTGTAG 60
CTGTAGCAGA AGCAAAAGGA AGCCGCTTGT GATAAATTTC AACTTCCATC AGCAAGCACT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0002--3D-structure
KW-0181--Complete proteome
KW-0539--Nucleus
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR022617--Rad60/SUMO-like_dom
IPR033950--Sumo
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom

PROSITE

PS50053--UBIQUITIN_2

Pfam

PF11976--Rad60-SLD

SMART

SM00213--UBQ

Gene Ontology

GO:0000940--C:condensed chromosome outer kinetochore
GO:0000794--C:condensed nuclear chromosome
GO:0000780--C:condensed nuclear chromosome, centromeric region
GO:0030496--C:midbody
GO:0005730--C:nucleolus
GO:0005634--C:nucleus
GO:0031386--F:protein tag
GO:0006464--P:cellular protein modification process
GO:0071560--P:cellular response to transforming growth factor beta stimulus
GO:0021952--P:central nervous system projection neuron axonogenesis
GO:0060997--P:dendritic spine morphogenesis
GO:0046843--P:dorsal appendage formation
GO:0055088--P:lipid homeostasis
GO:0007052--P:mitotic spindle organization
GO:0006909--P:phagocytosis
GO:0043406--P:positive regulation of MAP kinase activity
GO:0034126--P:positive regulation of MyD88-dependent toll-like receptor signaling pathway
GO:1903078--P:positive regulation of protein localization to plasma membrane
GO:0046579--P:positive regulation of Ras protein signal transduction
GO:0016926--P:protein desumoylation
GO:0006606--P:protein import into nucleus
GO:0016925--P:protein sumoylation
GO:0035073--P:pupariation
GO:0010906--P:regulation of glucose metabolic process
GO:0035186--P:syncytial blastoderm mitotic cell cycle
GO:0006099--P:tricarboxylic acid cycle

KEGG

dme:Dmel_CG4494

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001056	Aegilops tauschii	44.33	6.00e-17	78.20
IUUC-Aml-002090	Ailuropoda melanoleuca	74.07	6.00e-34	134.00
IUUC-Atr-002794	Amborella trichopoda	50.62	2.00e-19	86.30
IUUC-Apl-003372	Anas platyrhynchos	74.68	4.00e-33	131.00
IUUC-Aca-004778	Anolis carolinensis	71.74	9.00e-34	133.00
IUUC-Aly-005765	Arabidopsis lyrata	50.00	1.00e-20	90.10
IUUC-Ath-007391	Arabidopsis thaliana	50.57	8.00e-21	90.50
IUUC-Ago-007749	Ashbya gossypii	46.15	7.00e-16	73.90
IUUC-Acl-008286	Aspergillus clavatus	51.28	1.00e-19	86.30
IUUC-Afl-008650	Aspergillus flavus	52.56	5.00e-20	87.80
IUUC-Afu-008969	Aspergillus fumigatus	52.56	7.00e-20	87.40
IUUC-Ani-009300	Aspergillus nidulans	52.56	1.00e-19	86.70
IUUC-Ang-009651	Aspergillus niger	52.56	2.00e-19	85.90
IUUC-Ate-010503	Aspergillus terreus	40.00	1.00e-16	77.00
IUUC-Ame-011427	Astyanax mexicanus	69.15	2.00e-34	135.00
IUUC-Bgr-012250	Blumeria graminis	50.00	1.00e-18	83.60
IUUC-Bta-012492	Bos taurus	70.97	6.00e-34	134.00
IUUC-Bci-013625	Botrytis cinerea	49.37	2.00e-19	85.50
IUUC-Bdi-014847	Brachypodium distachyon	53.09	3.00e-20	89.00
IUUC-Bol-015977	Brassica oleracea	50.57	9.00e-21	90.50
IUUC-Bra-017542	Brassica rapa	50.57	1.00e-20	90.50
IUUC-Cel-018251	Caenorhabditis elegans	47.78	9.00e-22	93.60
IUUC-Cja-019875	Callithrix jacchus	75.61	5.00e-35	137.00
IUUC-Cfa-020733	Canis familiaris	72.41	5.00e-33	132.00
IUUC-Cpo-022241	Cavia porcellus	72.04	3.00e-34	135.00
IUUC-Cre-022980	Chlamydomonas reinhardtii	47.37	1.00e-16	76.60
IUUC-Csa-023133	Chlorocebus sabaeus	70.21	8.00e-34	133.00
IUUC-Cho-024767	Choloepus hoffmanni	52.94	2.00e-16	77.00
IUUC-Cin-025314	Ciona intestinalis	66.67	3.00e-33	132.00
IUUC-Csv-026212	Ciona savignyi	70.24	4.00e-33	131.00
IUUC-Cne-027072	Cryptococcus neoformans	46.88	2.00e-12	62.80
IUUC-Cme-027181	Cyanidioschyzon merolae	52.94	7.00e-21	90.90
IUUC-Dre-027357	Danio rerio	72.84	2.00e-33	132.00
IUUC-Dno-030039	Dasypus novemcinctus	72.04	3.00e-34	136.00
IUUC-Dor-030760	Dipodomys ordii	31.08	2.00e-06	45.40
IUUC-Dse-031390	Dothistroma septosporum	58.54	7.00e-24	100.00
IUUC-Ete-032934	Echinops telfairi	64.10	2.00e-26	108.00
IUUC-Eca-033890	Equus caballus	74.07	7.00e-34	134.00
IUUC-Eeu-034822	Erinaceus europaeus	52.27	8.00e-22	94.00
IUUC-Fca-036348	Felis catus	74.07	2.00e-33	132.00
IUUC-Fal-037226	Ficedula albicollis	74.68	1.00e-32	130.00
IUUC-Fox-037950	Fusarium oxysporum	48.84	3.00e-20	89.00
IUUC-Fso-038430	Fusarium solani	52.50	2.00e-20	89.70
IUUC-Gmo-038535	Gadus morhua	67.74	7.00e-34	134.00
IUUC-Ggr-040015	Gaeumannomyces graminis	56.41	9.00e-22	94.00
IUUC-Gga-040145	Gallus gallus	70.21	8.00e-34	133.00
IUUC-Gac-041723	Gasterosteus aculeatus	69.89	2.00e-34	135.00
IUUC-Gma-043216	Glycine max	49.43	6.00e-20	87.80
IUUC-Ggo-045467	Gorilla gorilla	70.21	8.00e-34	133.00
IUUC-Hsa-046074	Homo sapiens	71.28	1.00e-34	137.00
IUUC-Hvu-047514	Hordeum vulgare	51.69	1.00e-20	90.10
IUUC-Itr-048366	Ictidomys tridecemlineatus	75.00	2.00e-33	132.00
IUUC-Kpa-049243	Komagataella pastoris	43.75	1.00e-12	63.20
IUUC-Lch-050572	Latimeria chalumnae	72.94	7.00e-34	134.00
IUUC-Lpe-051129	Leersia perrieri	53.66	3.00e-21	92.40
IUUC-Loc-052560	Lepisosteus oculatus	69.89	2.00e-33	132.00
IUUC-Lma-052968	Leptosphaeria maculans	52.44	3.00e-21	92.40
IUUC-Laf-053557	Loxodonta africana	74.07	1.00e-33	133.00
IUUC-Mcc-054832	Macaca mulatta	71.59	5.00e-33	132.00
IUUC-Meu-056112	Macropus eugenii	55.00	3.00e-21	93.20
IUUC-Mor-057132	Magnaporthe oryzae	58.23	1.00e-22	97.10
IUUC-Mpo-057351	Magnaporthe poae	56.41	1.00e-21	93.60
IUUC-Mtr-057722	Medicago truncatula	49.43	4.00e-20	88.60
IUUC-Mla-059051	Melampsora laricipopulina	45.56	4.00e-16	75.50
IUUC-Mga-059768	Meleagris gallopavo	74.68	4.00e-33	131.00
IUUC-Mvi-060478	Microbotryum violaceum	44.44	8.00e-12	60.80
IUUC-Mmr-061052	Microcebus murinus	72.04	2.00e-34	136.00
IUUC-Mdo-062678	Monodelphis domestica	70.97	9.00e-34	133.00
IUUC-Mmu-063990	Mus musculus	70.21	8.00e-34	133.00
IUUC-Mac-064925	Musa acuminata	50.57	1.00e-20	90.50
IUUC-Mpu-065686	Mustela putorius furo	74.39	1.00e-34	136.00
IUUC-Mlu-066949	Myotis lucifugus	74.07	1.00e-33	132.00
IUUC-Nfi-068364	Neosartorya fischeri	52.56	5.00e-20	87.80
IUUC-Ncr-068663	Neurospora crassa	51.28	1.00e-19	87.00
IUUC-Nle-069631	Nomascus leucogenys	71.28	1.00e-34	136.00
IUUC-Opr-071104	Ochotona princeps	32.93	1.00e-07	50.40
IUUC-Ont-071512	Oreochromis niloticus	69.89	6.00e-34	134.00
IUUC-Oan-073080	Ornithorhynchus anatinus	71.59	4.00e-33	131.00
IUUC-Ocu-074239	Oryctolagus cuniculus	70.21	6.00e-34	134.00
IUUC-Oba-075425	Oryza barthii	53.85	1.00e-20	90.10
IUUC-Obr-076884	Oryza brachyantha	55.13	3.00e-21	92.40
IUUC-Ogl-077346	Oryza glaberrima	53.85	1.00e-20	90.10
IUUC-Ogu-078983	Oryza glumaepatula	52.44	7.00e-20	88.60
IUUC-Oin-079503	Oryza indica	53.85	1.00e-20	90.10
IUUC-Olo-080573	Oryza longistaminata	53.85	1.00e-20	90.10
IUUC-Ome-081885	Oryza meridionalis	53.85	2.00e-20	90.10
IUUC-Oni-082762	Oryza nivara	53.85	1.00e-20	90.10
IUUC-Opu-083431	Oryza punctata	53.85	3.00e-20	90.90
IUUC-Oru-084392	Oryza rufipogon	53.85	1.00e-20	90.10
IUUC-Osa-086070	Oryza sativa	53.85	1.00e-20	90.10
IUUC-Ola-086710	Oryzias latipes	69.89	8.00e-34	133.00
IUUC-Olu-087670	Ostreococcus lucimarinus	40.85	2.00e-13	65.90
IUUC-Oga-088989	Otolemur garnettii	71.74	8.00e-34	134.00
IUUC-Oar-089406	Ovis aries	74.07	7.00e-34	134.00
IUUC-Ptr-091447	Pan troglodytes	71.28	1.00e-34	137.00
IUUC-Pan-091791	Papio anubis	72.41	5.00e-33	132.00
IUUC-Psi-094000	Pelodiscus sinensis	70.21	8.00e-34	133.00
IUUC-Pno-094884	Phaeosphaeria nodorum	52.44	1.00e-21	93.60
IUUC-Ppa-095676	Physcomitrella patens	51.69	3.00e-20	89.00
IUUC-Pfo-097304	Poecilia formosa	69.15	1.00e-34	136.00
IUUC-Pab-098618	Pongo abelii	75.61	4.00e-35	137.00
IUUC-Pop-099042	Populus trichocarpa	49.43	2.00e-20	89.70
IUUC-Pca-100237	Procavia capensis	52.27	4.00e-20	89.40
IUUC-Ppe-101721	Prunus persica	50.57	1.00e-20	91.30
IUUC-Pva-102353	Pteropus vampyrus	47.06	1.00e-13	67.40
IUUC-Pgr-103683	Puccinia graminis	43.82	3.00e-17	79.00
IUUC-Ptt-103986	Puccinia triticina	43.82	4.00e-17	78.60
IUUC-Pte-104358	Pyrenophora teres	53.01	3.00e-22	95.50
IUUC-Pyt-104485	Pyrenophora triticirepentis	53.01	3.00e-22	95.50
IUUC-Rno-105136	Rattus norvegicus	70.97	1.00e-33	134.00
IUUC-Sce-106231	Saccharomyces cerevisiae	48.72	2.00e-16	76.30
IUUC-Sha-106682	Sarcophilus harrisii	75.31	4.00e-34	134.00
IUUC-Sja-107710	Schizosaccharomyces japonicus	57.50	1.00e-20	90.50
IUUC-Spo-108261	Schizosaccharomyces pombe	56.25	2.00e-20	90.10
IUUC-Smo-109229	Selaginella moellendorffii	48.84	4.00e-19	85.10
IUUC-Sit-110664	Setaria italica	36.78	5.00e-09	52.40
IUUC-Sly-110855	Solanum lycopersicum	51.72	3.00e-21	92.40
IUUC-Stu-111935	Solanum tuberosum	51.72	3.00e-21	92.40
IUUC-Sar-113337	Sorex araneus	60.64	1.00e-26	109.00
IUUC-Sbi-114801	Sorghum bicolor	53.85	2.00e-20	89.40
IUUC-Sre-115172	Sporisorium reilianum	45.57	5.00e-14	67.80
IUUC-Ssc-116092	Sus scrofa	70.97	8.00e-34	134.00
IUUC-Tgu-116815	Taeniopygia guttata	74.68	5.00e-33	130.00
IUUC-Tru-117955	Takifugu rubripes	72.04	9.00e-35	136.00
IUUC-Tsy-119358	Tarsius syrichta	47.06	2.00e-13	67.00
IUUC-Tni-120059	Tetraodon nigroviridis	68.82	9.00e-33	130.00
IUUC-Tca-121050	Theobroma cacao	49.43	2.00e-20	89.40
IUUC-Tre-121926	Trichoderma reesei	54.43	1.00e-20	90.10
IUUC-Tvi-122514	Trichoderma virens	54.43	1.00e-20	90.50
IUUC-Tae-122900	Triticum aestivum	53.09	1.00e-20	90.10
IUUC-Tur-126333	Triticum urartu	39.81	1.00e-15	75.10
IUUC-Tme-126902	Tuber melanosporum	51.25	9.00e-20	87.00
IUUC-Tbe-127363	Tupaia belangeri	66.67	8.00e-31	123.00
IUUC-Ttr-128166	Tursiops truncatus	52.27	2.00e-21	93.60
IUUC-Uma-129444	Ustilago maydis	45.57	9.00e-14	67.00
IUUC-Vda-129731	Verticillium dahliae	54.88	2.00e-22	96.30
IUUC-Vpa-130172	Vicugna pacos	52.27	2.00e-21	93.60
IUUC-Vvi-131743	Vitis vinifera	50.57	8.00e-21	90.50
IUUC-Xtr-132678	Xenopus tropicalis	72.04	3.00e-34	135.00
IUUC-Xma-133892	Xiphophorus maculatus	69.15	9.00e-35	137.00
IUUC-Yli-134507	Yarrowia lipolytica	45.05	1.00e-14	69.70
IUUC-Zma-134810	Zea mays	53.85	2.00e-20	89.40

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence