iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	GXD
DNA & RNA Element
AREsite	miRTarBase	microRNA	TRANSFAC
RAID2
Protein-protein Interaction
IID	iRefIndex	PINA	HINT
Mentha
Post-translational Modifications (PTMs)
dbPAF	PhosphositePlus
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	40.43	3.00e-128	456.00	IUUC-Cel-018432

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Mus musculus

Protein Sequence
(Fasta)

MEEELKCPVC GSLFREPIIL PCSHNVCLPC ARTIAVQTPD GEQHLPPPLL LSRGAAAAAT 60
PPDQDAAAGA TSGGAGANTA GGLGGGATGG GDHADKLSLY SETDSGYGSY TPSLKSPNGV 120

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Nucleotide Sequence
(Fasta)

GGGAGGGGGA TTCCCGAGCC AGCGGGTGCT CGCCCCCCAC CCGCCGCTGC AGCGTGGCGC 60
GGCCAAGGTC AGGGGCGCTG CAGGAACCGG AGCCGGCGAG GCCAGCCTGG GACGCTGCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0479--Metal-binding
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003649--Bbox_C
IPR013320--ConA-like_dom
IPR017903--COS_domain
IPR003961--FN3_dom
IPR013783--Ig-like_fold
IPR003877--SPRY_dom
IPR000315--Znf_B-box
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS51262--COS
PS50853--FN3
PS50119--ZF_BBOX
PS00518--ZF_RING_1

Pfam

PF00041--fn3
PF00622--SPRY
PF00643--zf-B_box
PF00097--zf-C3HC4

SMART

SM00502--BBC
SM00336--BBOX
SM00060--FN3
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005856--C:cytoskeleton
GO:0008270--F:zinc ion binding
GO:0046580--P:negative regulation of Ras protein signal transduction
GO:0010976--P:positive regulation of neuron projection development
GO:2000060--P:positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process

KEGG

mmu:330863

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aca-004773	Anolis carolinensis	78.32	0.00e+00	1182.00
IUUC-Ame-011429	Astyanax mexicanus	62.48	0.00e+00	911.00
IUUC-Cel-018432	Caenorhabditis elegans	34.77	3.00e-126	446.00
IUUC-Cja-019517	Callithrix jacchus	86.25	0.00e+00	1246.00
IUUC-Cfa-020240	Canis familiaris	87.10	0.00e+00	1271.00
IUUC-Cpo-022321	Cavia porcellus	84.57	0.00e+00	1242.00
IUUC-Csa-024114	Chlorocebus sabaeus	91.67	0.00e+00	1308.00
IUUC-Cho-024399	Choloepus hoffmanni	91.26	3.00e-155	541.00
IUUC-Cin-025387	Ciona intestinalis	45.57	2.00e-158	553.00
IUUC-Ete-032674	Echinops telfairi	85.16	0.00e+00	1041.00
IUUC-Eca-034107	Equus caballus	86.99	0.00e+00	1228.00
IUUC-Eeu-034755	Erinaceus europaeus	97.44	8.00e-140	490.00
IUUC-Fal-036997	Ficedula albicollis	88.93	0.00e+00	918.00
IUUC-Ggo-044878	Gorilla gorilla	88.12	0.00e+00	1274.00
IUUC-Itr-047884	Ictidomys tridecemlineatus	92.47	0.00e+00	1318.00
IUUC-Loc-052458	Lepisosteus oculatus	68.22	0.00e+00	1056.00
IUUC-Mga-059961	Meleagris gallopavo	90.06	0.00e+00	894.00
IUUC-Mdo-062608	Monodelphis domestica	83.52	0.00e+00	1107.00
IUUC-Mpu-065904	Mustela putorius furo	87.58	0.00e+00	1279.00
IUUC-Opr-070450	Ochotona princeps	86.81	0.00e+00	1167.00
IUUC-Ont-071791	Oreochromis niloticus	65.71	0.00e+00	1001.00
IUUC-Oan-073661	Ornithorhynchus anatinus	89.13	3.00e-126	443.00
IUUC-Ocu-074651	Oryctolagus cuniculus	88.85	0.00e+00	1263.00
IUUC-Oga-088823	Otolemur garnettii	88.65	0.00e+00	1258.00
IUUC-Ptr-091267	Pan troglodytes	88.12	0.00e+00	1274.00
IUUC-Pan-092803	Papio anubis	90.83	0.00e+00	1293.00
IUUC-Sha-106771	Sarcophilus harrisii	93.42	0.00e+00	954.00
IUUC-Sar-113278	Sorex araneus	84.66	0.00e+00	1141.00
IUUC-Tgu-117319	Taeniopygia guttata	83.25	0.00e+00	1030.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence