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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Sce-106420
UUCD1 version UUC-SaC-00160
Ensembl Protein ID YGL100W
UniProt Accession P53011; D6VU45; SEH1_YEAST
Genbank Protein ID CAA62480.1; CAA96806.1; AAS56823.1; DAA08006.1
Protein Name Nucleoporin SEH1; Nuclear pore protein SEH1; SEC13 homolog 1
Genbank Nucleotide ID X90994; Z72622; AY558497; BK006941
Gene Name SEH1; YGL100W
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
YGL100W YGL100W YGL100W
Annotation
mRNA Expression
GEOFFGED
Protein-protein Interaction
IIDiRefIndexHINTMentha
Protein 3D Structure
PDBMMDB
Post-translational Modifications (PTMs)
CPLMdbPAFdbPTMUniProt
BioGRID
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 7.50e-28 93.9 303 332
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 2    Htdsvtclaf..sdtllvsGsdDgtikvWD 29
           H+++v+++++  ++t+l+s++dDg++++W 
   Q: 303  HNGEVWSVSWnlTGTILSSAGDDGKVRLWK 332
           9**********766***************8 PP
   
Organism Saccharomyces cerevisiae
Functional Description
(View)

Functional Description


     Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. Involved in nuclear poly(A)+ RNA export and NPC biogenesis. It is also required for normal nuclear morphology. Component of the SEA complex which coats the vacuolar membrane and is involved in intracellular trafficking, autophagy, response to nitrogen starvation, and amino acid biogenesis.
 Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. Involved in nuclear poly(A)+ RNA export and NPC biogenesis. It is also required for normal nuclear morphology. Component of the SEA complex which coats the vacuolar membrane and is involved in intracellular trafficking, autophagy, response to nitrogen starvation, and amino acid biogenesis.
Protein Sequence
(Fasta)
MQPFDSGHDD LVHDVVYDFY GRHVATCSSD QHIKVFKLDK DTSNWELSDS WRAHDSSIVA 60
IDWASPEYGR IIASASYDKT VKLWEEDPDQ EECSGRRWNK LCTLNDSKGS LYSVKFAPAH 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Sce-106420|E3,WD_repeat|Saccharomyces cerevisiae
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGCAACCAT TTGATAGTGG GCATGATGAT TTAGTTCATG ATGTCGTTTA TGACTTTTAC 60
GGAAGACATG TGGCAACATG CTCTTCTGAT CAACATATTA AAGTTTTTAA ATTAGACAAG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Sce-106420|E3,WD_repeat|Saccharomyces cerevisiae
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0002--3D-structure
KW-0181--Complete proteome
KW-0903--Direct protein sequencing
KW-0472--Membrane
KW-0509--mRNA transport
KW-0906--Nuclear pore complex
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0677--Repeat
KW-0811--Translocation
KW-0813--Transport
KW-0926--Vacuole
KW-0853--WD repeat
Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF00400--WD40
SMART

SM00320--WD40
Gene Ontology

GO:0097042--C:extrinsic component of fungal-type vacuolar membrane
GO:0031965--C:nuclear membrane
GO:0005643--C:nuclear pore
GO:0031080--C:nuclear pore outer ring
GO:0035859--C:Seh1-associated complex
GO:0017056--F:structural constituent of nuclear pore
GO:0051028--P:mRNA transport
GO:0006913--P:nucleocytoplasmic transport
GO:1904263--P:positive regulation of TORC1 signaling
GO:0015031--P:protein transport
KEGG sce:YGL100W
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001926 Ailuropoda melanoleuca 33.24 7.00e-52 196.00
IUUC-Apl-003654 Anas platyrhynchos 30.97 1.00e-40 157.00
IUUC-Aca-004378 Anolis carolinensis 31.61 7.00e-42 162.00
IUUC-Ago-007816 Ashbya gossypii 67.62 9.00e-144 500.00
IUUC-Acl-008248 Aspergillus clavatus 31.23 2.00e-41 160.00
IUUC-Afl-008667 Aspergillus flavus 30.28 4.00e-40 156.00
IUUC-Afu-008961 Aspergillus fumigatus 30.00 4.00e-41 159.00
IUUC-Ani-009218 Aspergillus nidulans 35.14 2.00e-38 150.00
IUUC-Ang-009693 Aspergillus niger 33.83 9.00e-37 145.00
IUUC-Ate-010349 Aspergillus terreus 34.77 4.00e-38 149.00
IUUC-Ame-011945 Astyanax mexicanus 34.38 6.00e-53 199.00
IUUC-Bta-013306 Bos taurus 33.24 4.00e-52 196.00
IUUC-Cel-018235 Caenorhabditis elegans 26.18 2.00e-31 127.00
IUUC-Cja-018849 Callithrix jacchus 33.24 4.00e-52 196.00
IUUC-Cfa-020841 Canis familiaris 33.53 9.00e-49 187.00
IUUC-Cpo-021379 Cavia porcellus 32.94 5.00e-51 192.00
IUUC-Csa-023900 Chlorocebus sabaeus 33.24 6.00e-52 196.00
IUUC-Cho-024660 Choloepus hoffmanni 30.65 3.00e-40 156.00
IUUC-Cin-025471 Ciona intestinalis 31.40 9.00e-39 152.00
IUUC-Csv-026242 Ciona savignyi 39.89 1.00e-37 147.00
IUUC-Cgl-026501 Colletotrichum gloeosporioides 28.17 4.00e-30 123.00
IUUC-Dre-028068 Danio rerio 34.94 4.00e-54 202.00
IUUC-Dno-029981 Dasypus novemcinctus 35.03 1.00e-54 205.00
IUUC-Dse-031420 Dothistroma septosporum 28.88 9.00e-40 155.00
IUUC-Dme-031763 Drosophila melanogaster 30.77 2.00e-49 187.00
IUUC-Eca-033425 Equus caballus 30.32 8.00e-41 158.00
IUUC-Eeu-035119 Erinaceus europaeus 41.35 5.00e-19 86.70
IUUC-Fca-036520 Felis catus 33.24 5.00e-52 196.00
IUUC-Fal-037234 Ficedula albicollis 30.97 4.00e-40 159.00
IUUC-Gmo-039013 Gadus morhua 32.95 4.00e-52 196.00
IUUC-Gga-041059 Gallus gallus 33.53 4.00e-52 196.00
IUUC-Gac-041337 Gasterosteus aculeatus 33.14 1.00e-52 197.00
IUUC-Ggo-044944 Gorilla gorilla 33.24 4.00e-52 196.00
IUUC-Hsa-046038 Homo sapiens 33.24 4.00e-52 196.00
IUUC-Itr-048858 Ictidomys tridecemlineatus 30.65 1.00e-40 157.00
IUUC-Kpa-049201 Komagataella pastoris 55.62 4.00e-107 379.00
IUUC-Lch-050466 Latimeria chalumnae 29.22 2.00e-42 164.00
IUUC-Loc-052773 Lepisosteus oculatus 32.71 4.00e-51 193.00
IUUC-Lma-053000 Leptosphaeria maculans 27.22 4.00e-37 147.00
IUUC-Laf-053409 Loxodonta africana 33.24 4.00e-52 196.00
IUUC-Mor-057223 Magnaporthe oryzae 25.06 3.00e-27 114.00
IUUC-Mpo-057506 Magnaporthe poae 25.95 5.00e-21 93.60
IUUC-Mla-058820 Melampsora laricipopulina 27.84 2.00e-35 140.00
IUUC-Mga-059348 Meleagris gallopavo 30.97 6.00e-41 159.00
IUUC-Mmr-060977 Microcebus murinus 32.48 3.00e-34 136.00
IUUC-Mdo-061806 Monodelphis domestica 33.24 1.00e-51 194.00
IUUC-Mmu-064328 Mus musculus 34.76 2.00e-55 207.00
IUUC-Mpu-066873 Mustela putorius furo 33.24 7.00e-52 196.00
IUUC-Mlu-067563 Myotis lucifugus 33.43 3.00e-49 186.00
IUUC-Nfi-068299 Neosartorya fischeri 30.36 3.00e-41 160.00
IUUC-Nle-068977 Nomascus leucogenys 31.80 2.00e-44 171.00
IUUC-Ont-072644 Oreochromis niloticus 33.43 1.00e-52 197.00
IUUC-Oan-073098 Ornithorhynchus anatinus 30.32 4.00e-40 156.00
IUUC-Ocu-073911 Oryctolagus cuniculus 33.24 5.00e-52 196.00
IUUC-Ola-087096 Oryzias latipes 33.81 2.00e-52 197.00
IUUC-Oga-088798 Otolemur garnettii 33.24 3.00e-52 196.00
IUUC-Oar-090298 Ovis aries 30.65 2.00e-39 157.00
IUUC-Ptr-091074 Pan troglodytes 32.94 4.00e-52 196.00
IUUC-Pan-092013 Papio anubis 33.47 1.00e-36 144.00
IUUC-Psi-093508 Pelodiscus sinensis 30.00 6.00e-41 159.00
IUUC-Pma-094288 Petromyzon marinus 41.53 9.00e-36 140.00
IUUC-Pno-094777 Phaeosphaeria nodorum 27.87 2.00e-37 147.00
IUUC-Pfo-096384 Poecilia formosa 33.71 2.00e-53 200.00
IUUC-Pab-098629 Pongo abelii 33.24 3.00e-52 197.00
IUUC-Pca-100322 Procavia capensis 41.18 1.00e-19 89.00
IUUC-Pva-102861 Pteropus vampyrus 33.53 2.00e-52 197.00
IUUC-Pte-104375 Pyrenophora teres 28.77 2.00e-37 147.00
IUUC-Pyt-104586 Pyrenophora triticirepentis 28.77 2.00e-37 147.00
IUUC-Rno-104895 Rattus norvegicus 32.08 1.00e-42 167.00
IUUC-Sha-106829 Sarcophilus harrisii 29.91 9.00e-41 158.00
IUUC-Sja-107923 Schizosaccharomyces japonicus 39.31 8.00e-83 298.00
IUUC-Spo-108184 Schizosaccharomyces pombe 40.99 7.00e-84 301.00
IUUC-Sar-113279 Sorex araneus 30.32 6.00e-40 155.00
IUUC-Ssc-115589 Sus scrofa 31.33 1.00e-41 161.00
IUUC-Tgu-117523 Taeniopygia guttata 33.53 3.00e-52 196.00
IUUC-Tru-117985 Takifugu rubripes 31.96 4.00e-40 159.00
IUUC-Tsy-118913 Tarsius syrichta 30.30 5.00e-34 136.00
IUUC-Tni-120670 Tetraodon nigroviridis 34.10 4.00e-54 202.00
IUUC-Tme-126885 Tuber melanosporum 42.70 1.00e-80 291.00
IUUC-Tbe-127344 Tupaia belangeri 28.28 1.00e-32 131.00
IUUC-Ttr-128347 Tursiops truncatus 30.65 2.00e-40 157.00
IUUC-Vpa-130656 Vicugna pacos 31.65 5.00e-41 159.00
IUUC-Xtr-132736 Xenopus tropicalis 32.36 1.00e-52 197.00
IUUC-Xma-133678 Xiphophorus maculatus 33.53 2.00e-53 200.00
IUUC-Yli-134659 Yarrowia lipolytica 50.14 8.00e-106 374.00
Created Date 25-Jun-2017

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