• HOME
  • BROWSE
  • SEARCH
  • LINK
  • DOWNLOAD
  • USER GUIDE
  • Protein
  • Gene
  • Annotation
  • Details
  • Classification
  • Domain Profile
  • Function
  • Protein Sequence
  • Nucleotide Sequence
  • Keyword
  • GO
  • Orthology
  • TOP

Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Hsa-045687
Ensembl Protein ID ENSP00000419960.1
UniProt Accession Q92734; D3DN49; G5E9V1; K0J5S8; K0J6K2; Q15656; Q969I2; TFG_HUMAN
Genbank Protein ID CAA69264.1; BAM48926.1; BAM48927.1; BAG52721.1; AAP36096.1; CAG33062.1; EAW79813.1; EAW79814.1; EAW79815.1; EAW79816.1; EAW79817.1; AAH01483.1; AAH09241.1; AAH23599.1; CAA59936.1
Protein Name Protein TFG; TRK-fused gene protein
Genbank Nucleotide ID Y07968; AB731569; AB731570; AK093456; BT007428; CR456781; AC068763; CH471052; CH471052; CH471052; CH471052; BC001483; BC009241; BC023599; X85960
Gene Name TFG
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000114354.13 ENST00000418917.6 ENSP00000397182.2
ENSG00000114354.13 ENST00000490574.5 ENSP00000419960.1
ENSG00000114354.13 ENST00000620299.4 ENSP00000479981.1
Annotation
Cancer Mutation
TCGAICGCCOSMICCGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressTCGAICGC
COSMICTHPAHPM
DNA & RNA Element
UTRdbAREsitecircBasecircRNADb
CircNetmiRTarBasemicroRNATRANSFAC
miRWalkRepTarSomamiRmiRcode
RAID2
Protein-protein Interaction
IIDiRefIndexPINAHINT
MenthaInWeb_IM
Disease-associated Information
ClinVarOMIM
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusdbPTM
HPRDPhospho.ELMUniProtPHOSIDA
BioGRIDmUbiSiDa
DNA Methylation
MethyCancerTCGAICGC
Protein Expression/Proteomics
THPAHPMGPMDB
Status Reviewed
Details
Family Domain References (PMIDs)
ULD/UDP/UFD/PB1 PB1 17726178; 24613659
Classification
Family E-value Score Start End
ULD/UDP/UFD/PB1 1.50e-17 65.2 11 89
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   ULD/UDP/UFD/PB1
   S: 2    vrvkvsykgeirsfaldlekpgkfedLlkavrt...ltelknsevalkYeDedGDlvtlksDedldkavsllaskksllrlliq 82
           +++k++++++ir++ ++ ++++++++L+ ++++    + l+n+ev++kY+DedGDl+t+++++dl++a++    ++++l+l+++
   Q: 11   LIIKAQLGEDIRRIPIH-NEDITYDELVLMMQRvfrGKLLSNDEVTIKYKDEDGDLITIFDSSDLSFAIQ----CSRILKLTLF 89
           579**************.***************98888********************************....9******987 PP
   
Organism Homo sapiens
Functional Description
(View)

Functional Description


     Plays a role in the normal dynamic function of the endoplasmic reticulum (ER) and its associated microtubules (PubMed:23479643, PubMed:27813252).
 Plays a role in the normal dynamic function of the endoplasmic reticulum (ER) and its associated microtubules (PubMed:23479643, PubMed:27813252).
Protein Sequence
(Fasta)
MNGQLDLSGK LIIKAQLGED IRRIPIHNED ITYDELVLMM QRVFRGKLLS NDEVTIKYKD 60
EDGDLITIFD SSDLSFAIQC SRILKLTLFV NGQPRPLESS QVKYLRRELI ELRNKVNRLL 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Hsa-045687|ULD,PB1|Homo sapiens
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TTCCTAAATC CCGTCATCCA GTGAGAAAGC AGGGACTCTT CGGCCTAGGC AGCCGGGACC 60
CAGCCAGCCC TGCGCCTCGC GCCGTCGCGC ATGCGTCCTG GGTATGTCCA CGCGCAATAA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Hsa-045687|ULD,PB1|Homo sapiens
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0007--Acetylation
KW-0025--Alternative splicing
KW-0160--Chromosomal rearrangement
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0903--Direct protein sequencing
KW-0225--Disease mutation
KW-0256--Endoplasmic reticulum
KW-0890--Hereditary spastic paraplegia
KW-0488--Methylation
KW-0523--Neurodegeneration
KW-0622--Neuropathy
KW-0597--Phosphoprotein
KW-0621--Polymorphism
KW-0656--Proto-oncogene
KW-1185--Reference proteome
Interpro

IPR000270--PB1_dom
IPR033512--TFG
PROSITE

PS51745--PB1
Pfam

PF00564--PB1
SMART

SM00666--PB1
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0000139--C:Golgi membrane
GO:0042802--F:identical protein binding
GO:0004871--F:signal transducer activity
GO:0048208--P:COPII vesicle coating
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
KEGG hsa:10342
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000264 Aegilops tauschii 24.32 3.10e-02 31.60
IUUC-Atr-002452 Amborella trichopoda 29.31 3.10e-02 32.70
IUUC-Apl-003220 Anas platyrhynchos 90.46 2.00e-112 398.00
IUUC-Aca-004830 Anolis carolinensis 89.47 1.00e-107 382.00
IUUC-Ame-010792 Astyanax mexicanus 82.41 8.00e-49 187.00
IUUC-Bta-012950 Bos taurus 94.26 7.00e-137 480.00
IUUC-Bdi-014647 Brachypodium distachyon 24.32 4.40e-02 31.60
IUUC-Cel-018680 Caenorhabditis elegans 32.46 4.00e-11 62.80
IUUC-Cja-019530 Callithrix jacchus 98.75 1.00e-160 559.00
IUUC-Cfa-020019 Canis familiaris 97.51 3.00e-107 382.00
IUUC-Cpo-021749 Cavia porcellus 95.51 9.00e-136 476.00
IUUC-Csa-023127 Chlorocebus sabaeus 99.58 1.00e-121 429.00
IUUC-Cho-024790 Choloepus hoffmanni 93.81 2.00e-95 342.00
IUUC-Cin-025204 Ciona intestinalis 66.38 7.00e-42 164.00
IUUC-Csv-025833 Ciona savignyi 63.16 2.00e-42 165.00
IUUC-Dre-027850 Danio rerio 79.68 4.00e-75 275.00
IUUC-Dno-029244 Dasypus novemcinctus 95.01 1.00e-138 486.00
IUUC-Dor-030191 Dipodomys ordii 97.94 9.00e-108 383.00
IUUC-Eca-033719 Equus caballus 97.93 2.00e-120 425.00
IUUC-Eeu-035270 Erinaceus europaeus 96.91 2.00e-106 379.00
IUUC-Fca-035804 Felis catus 98.56 2.00e-116 412.00
IUUC-Fal-037426 Ficedula albicollis 91.39 2.00e-108 385.00
IUUC-Gmo-038472 Gadus morhua 78.30 2.00e-91 328.00
IUUC-Gga-040715 Gallus gallus 91.87 3.00e-109 388.00
IUUC-Gac-041966 Gasterosteus aculeatus 78.95 1.00e-92 332.00
IUUC-Gma-042930 Glycine max 23.39 8.00e-03 34.70
IUUC-Hvu-047138 Hordeum vulgare 37.14 6.00e-04 39.70
IUUC-Itr-048521 Ictidomys tridecemlineatus 96.51 6.00e-137 480.00
IUUC-Lch-049822 Latimeria chalumnae 77.81 1.00e-123 436.00
IUUC-Lpe-050724 Leersia perrieri 24.36 1.60e-02 33.10
IUUC-Laf-053735 Loxodonta africana 96.62 9.00e-118 416.00
IUUC-Mcc-054955 Macaca mulatta 99.75 5.00e-150 523.00
IUUC-Mtr-058408 Medicago truncatula 33.93 5.50e-02 32.00
IUUC-Mmr-061160 Microcebus murinus 98.34 3.00e-122 431.00
IUUC-Mdo-062388 Monodelphis domestica 96.27 3.00e-119 421.00
IUUC-Mmu-063730 Mus musculus 97.58 2.00e-114 405.00
IUUC-Mac-065660 Musa acuminata 36.96 7.90e-02 30.00
IUUC-Mpu-065683 Mustela putorius furo 97.93 1.00e-120 426.00
IUUC-Mlu-067270 Myotis lucifugus 96.68 1.00e-119 423.00
IUUC-Nle-069491 Nomascus leucogenys 99.00 8.00e-149 520.00
IUUC-Opr-071160 Ochotona princeps 94.74 4.00e-111 394.00
IUUC-Ont-071943 Oreochromis niloticus 81.82 1.00e-93 336.00
IUUC-Oan-073255 Ornithorhynchus anatinus 94.74 1.00e-110 393.00
IUUC-Ocu-074001 Oryctolagus cuniculus 94.28 5.00e-137 480.00
IUUC-Obr-076745 Oryza brachyantha 30.36 1.40e-01 30.00
IUUC-Ogu-078946 Oryza glumaepatula 26.25 6.40e-02 30.40
IUUC-Oga-088931 Otolemur garnettii 97.01 6.00e-157 546.00
IUUC-Oar-089653 Ovis aries 94.76 1.00e-137 483.00
IUUC-Ptr-091043 Pan troglodytes 100.00 1.00e-150 526.00
IUUC-Pan-092436 Papio anubis 98.27 3.00e-146 511.00
IUUC-Psi-093566 Pelodiscus sinensis 91.88 2.00e-109 389.00
IUUC-Pfo-096649 Poecilia formosa 82.38 8.00e-94 337.00
IUUC-Pab-098182 Pongo abelii 99.25 2.00e-149 522.00
IUUC-Pva-102449 Pteropus vampyrus 95.40 5.00e-61 228.00
IUUC-Rno-105324 Rattus norvegicus 98.04 1.00e-112 400.00
IUUC-Sha-106837 Sarcophilus harrisii 97.05 3.00e-118 418.00
IUUC-Sit-110216 Setaria italica 33.93 1.40e-01 30.80
IUUC-Sar-112937 Sorex araneus 79.10 4.00e-72 265.00
IUUC-Sbi-114334 Sorghum bicolor 25.00 6.20e-02 31.20
IUUC-Ssc-115848 Sus scrofa 93.24 2.00e-108 385.00
IUUC-Tgu-117454 Taeniopygia guttata 90.91 3.00e-108 385.00
IUUC-Tru-117548 Takifugu rubripes 85.71 4.00e-90 325.00
IUUC-Tsy-119108 Tarsius syrichta 86.28 5.00e-157 547.00
IUUC-Tni-120677 Tetraodon nigroviridis 81.90 9.00e-93 333.00
IUUC-Tca-121767 Theobroma cacao 32.14 4.50e-02 32.30
IUUC-Tae-123421 Triticum aestivum 24.32 4.20e-02 31.60
IUUC-Tur-126762 Triticum urartu 33.33 1.40e+00 26.90
IUUC-Tbe-127251 Tupaia belangeri 97.94 2.00e-107 382.00
IUUC-Ttr-129157 Tursiops truncatus 91.77 5.00e-147 514.00
IUUC-Vpa-130130 Vicugna pacos 81.30 1.00e-114 406.00
IUUC-Xtr-132566 Xenopus tropicalis 88.73 4.00e-102 364.00
IUUC-Xma-134169 Xiphophorus maculatus 83.33 1.00e-97 350.00
Created Date 25-Jun-2017

https://dev.news.makassarkota.go.id/public/pgsoft-demo/ https://jdih.sumbawabaratkab.go.id/lato/pg-soft-demo/ https://dev.news.makassarkota.go.id/public/slot-gacor/ http://pbb.tanahbumbukab.go.id/-/slot-gacor/ slot gacor https://siakad.unipra.ac.id/sass/slot-gacor-x500/ http://kpm.dinus.ac.id/assets/images/berita/slot/
Copyright © 2004-2017.The CUCKOO Workgroup. All Rights Reserved