iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
iRefIndex
Post-translational Modifications (PTMs)
dbPAF	PHOSIDA
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.10e-13	49.3	1282	1316

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclafsdtllvsGsdDgtikvWDlrtgvl 35
           gH+ +v +++ +++l+v+Gs D t k+WD+  ++ 
   Q: 1282 GHARGVLSVDVNEKLMVTGSKDRTAKLWDIEACRE 1316
           89999*****9779***************877665 PP

Organism

Caenorhabditis elegans

Protein Sequence
(Fasta)

MADTCVQVAL RIRPQGNREK LEGSRVCTSV LPNDPQVTIG GDRSFTYDHV FDMPTLQYVV 60
YESCVEKLVD GLFDGYNATV LAYGQTGSGK THTMGTAFDA AVTQKEEDLG VIPRAIQHTF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGAAAATCAA TCAATTTGGA TGGAATAATC ACTGAAAAAG AATCATCATC CAACAAATTA 60
GGTGAAAATG GCGGACACTT GTGTGCAGGT CGCATTACGG TAACATTTTA AAGTATAGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0505--Motor protein
KW-0547--Nucleotide-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR019821--Kinesin_motor_CS
IPR001752--Kinesin_motor_dom
IPR027417--P-loop_NTPase
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00411--KINESIN_MOTOR_1
PS50067--KINESIN_MOTOR_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00225--Kinesin
PF00400--WD40

PRINTS

PR00380--KINESINHEAVY

SMART

SM00129--KISc
SM00320--WD40

Gene Ontology

GO:0005871--C:kinesin complex
GO:0005524--F:ATP binding
GO:0016887--F:ATPase activity
GO:0003777--F:microtubule motor activity
GO:0007018--P:microtubule-based movement

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001391	Ailuropoda melanoleuca	53.88	1.00e-151	530.00
IUUC-Apl-003353	Anas platyrhynchos	52.84	2.00e-149	523.00
IUUC-Aca-004467	Anolis carolinensis	52.02	7.00e-152	530.00
IUUC-Ame-011237	Astyanax mexicanus	52.39	2.00e-152	532.00
IUUC-Bta-013485	Bos taurus	53.86	3.00e-147	515.00
IUUC-Cja-019385	Callithrix jacchus	53.80	7.00e-149	521.00
IUUC-Cfa-020986	Canis familiaris	53.62	6.00e-149	521.00
IUUC-Cpo-022297	Cavia porcellus	54.13	2.00e-149	523.00
IUUC-Csa-023685	Chlorocebus sabaeus	53.29	7.00e-150	524.00
IUUC-Cho-024531	Choloepus hoffmanni	54.51	3.00e-77	283.00
IUUC-Cin-025160	Ciona intestinalis	29.88	7.00e-40	157.00
IUUC-Csv-026158	Ciona savignyi	50.09	7.00e-137	481.00
IUUC-Dre-028532	Danio rerio	53.01	3.00e-147	515.00
IUUC-Dno-029972	Dasypus novemcinctus	54.33	1.00e-150	526.00
IUUC-Dor-030673	Dipodomys ordii	48.42	2.00e-117	416.00
IUUC-Ete-032705	Echinops telfairi	46.68	5.00e-119	421.00
IUUC-Eca-033518	Equus caballus	53.11	5.00e-149	521.00
IUUC-Eeu-035338	Erinaceus europaeus	54.34	4.00e-145	508.00
IUUC-Fca-036197	Felis catus	53.91	4.00e-150	525.00
IUUC-Fal-037534	Ficedula albicollis	54.98	3.00e-150	525.00
IUUC-Gmo-039407	Gadus morhua	52.61	6.00e-111	394.00
IUUC-Gga-040687	Gallus gallus	54.26	3.00e-149	522.00
IUUC-Gac-041626	Gasterosteus aculeatus	55.98	5.00e-144	504.00
IUUC-Ggo-044457	Gorilla gorilla	53.82	1.00e-149	523.00
IUUC-Hsa-046372	Homo sapiens	54.07	1.00e-151	530.00
IUUC-Itr-049068	Ictidomys tridecemlineatus	33.33	5.00e-51	195.00
IUUC-Lch-049786	Latimeria chalumnae	51.45	6.00e-147	514.00
IUUC-Loc-052703	Lepisosteus oculatus	51.89	1.00e-150	526.00
IUUC-Laf-054018	Loxodonta africana	53.16	3.00e-146	512.00
IUUC-Mcc-055558	Macaca mulatta	53.49	3.00e-150	525.00
IUUC-Meu-056080	Macropus eugenii	50.00	1.00e-130	460.00
IUUC-Mga-059816	Meleagris gallopavo	54.73	5.00e-143	501.00
IUUC-Mmr-060773	Microcebus murinus	53.88	2.00e-151	529.00
IUUC-Mdo-062845	Monodelphis domestica	51.60	2.00e-152	532.00
IUUC-Mmu-063967	Mus musculus	55.05	3.00e-150	525.00
IUUC-Mpu-066354	Mustela putorius furo	54.07	7.00e-152	531.00
IUUC-Mlu-067599	Myotis lucifugus	53.62	2.00e-149	523.00
IUUC-Nle-069477	Nomascus leucogenys	53.68	1.00e-150	526.00
IUUC-Opr-070325	Ochotona princeps	48.58	4.00e-121	428.00
IUUC-Ont-071938	Oreochromis niloticus	55.51	7.00e-152	531.00
IUUC-Oan-073055	Ornithorhynchus anatinus	53.40	1.00e-148	520.00
IUUC-Ocu-073855	Oryctolagus cuniculus	54.67	5.00e-149	521.00
IUUC-Ola-086604	Oryzias latipes	54.06	4.00e-150	525.00
IUUC-Oga-088799	Otolemur garnettii	52.13	2.00e-99	356.00
IUUC-Oar-089629	Ovis aries	53.54	1.00e-147	517.00
IUUC-Ptr-090535	Pan troglodytes	33.63	6.00e-51	194.00
IUUC-Pan-092214	Papio anubis	53.29	1.00e-149	523.00
IUUC-Psi-093752	Pelodiscus sinensis	53.33	8.00e-144	504.00
IUUC-Pfo-097448	Poecilia formosa	52.26	1.00e-148	520.00
IUUC-Pab-097984	Pongo abelii	53.88	8.00e-151	527.00
IUUC-Pca-100781	Procavia capensis	57.57	4.00e-140	491.00
IUUC-Pva-102306	Pteropus vampyrus	52.71	8.00e-147	514.00
IUUC-Rno-105872	Rattus norvegicus	55.25	5.00e-151	528.00
IUUC-Sha-106938	Sarcophilus harrisii	51.74	3.00e-138	485.00
IUUC-Ssc-115810	Sus scrofa	53.29	9.00e-150	523.00
IUUC-Tgu-117076	Taeniopygia guttata	54.96	3.00e-146	512.00
IUUC-Tru-118091	Takifugu rubripes	54.17	6.00e-150	524.00
IUUC-Tsy-119020	Tarsius syrichta	54.24	3.00e-149	522.00
IUUC-Tni-120813	Tetraodon nigroviridis	55.69	5.00e-153	535.00
IUUC-Tbe-127494	Tupaia belangeri	50.92	7.00e-46	178.00
IUUC-Ttr-128824	Tursiops truncatus	53.72	9.00e-76	278.00
IUUC-Vpa-130675	Vicugna pacos	57.97	1.00e-109	390.00
IUUC-Xtr-132829	Xenopus tropicalis	55.51	4.00e-152	531.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence