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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Hsa-046949
Ensembl Protein ID ENSP00000364449.1
UniProt Accession Q9Y2K2; A1A5A8; Q59FY2; Q5M9N1; Q6P3R6; Q8IYM8; Q9HA50; SIK3_HUMAN
Genbank Protein ID BAA76843.2; AAH35583.3; AAH63887.1; AAH86858.1; AAI28511.1; BAD92564.1; BAB14006.1; AAT06749.1
Protein Name Serine/threonine-protein kinase SIK3; Salt-inducible kinase 3; Serine/threonine-protein kinase QSK
Genbank Nucleotide ID AB023216; AP000936; BC063887; BC086858; BC128510; AB209327; AK022302; AY598338
Gene Name SIK3; KIAA0999; QSK; L19
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000160584.15 ENST00000445177.5 ENSP00000391295.1
ENSG00000160584.15 ENST00000375300.5 ENSP00000364449.1
ENSG00000160584.15 ENST00000454905.5 ENSP00000392849.1
ENSG00000160584.15 ENST00000415541.5 ENSP00000392761.1
ENSG00000160584.15 ENST00000446921.6 ENSP00000390442.2
ENSG00000160584.15 ENST00000413553.1 ENSP00000414347.1
Annotation
Cancer Mutation
TCGAICGCCOSMICCGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressTCGAICGC
COSMICTHPAHPM
DNA & RNA Element
UTRdbAREsitecircBasecircRNADb
CircNetmiRTarBasemicroRNATRANSFAC
TargetScanRepTarmiRNAMapSomamiR
miRcodeRAID2
Protein-protein Interaction
IIDiRefIndexMentha
Disease-associated Information
GWASdbOMIM
Drug and target
TTDGRAC
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusdbPTM
HPRDPhospho.ELMUniProtBioGRID
mUbiSiDa
DNA Methylation
MethyCancerTCGAICGCCOSMIC
Protein Expression/Proteomics
THPAHPMGPMDB
Status Reviewed
Details
Family Domain References (PMIDs)
UBD/Alpha-Helix/UBA UBA 24061540
Organism Homo sapiens
Protein Sequence
(Fasta)
MAAAAASGAG GAAGAGTGGA GPAGRLLPPP APGSPAAPAA VSPAAGQPRP PAPASRGPMP 60
ARIGYYEIDR TIGKGNFAVV KRATHLVTKA KVAIKIIDKT QLDEENLKKI FREVQIMKML 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Hsa-046949|UBD,UBA|Homo sapiens
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GGAGGTTTCA CTGCACAACA AGATGGCGGC GGCGGCGGCG AGCGGAGCTG GCGGGGCTGC 60
CGGGGCCGGG ACTGGGGGAG CCGGGCCCGC GGGCCGCCTG CTGCCTCCGC CCGCGCCGGG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Hsa-046949|UBD,UBA|Homo sapiens
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0418--Kinase
KW-0460--Magnesium
KW-0479--Metal-binding
KW-0488--Methylation
KW-0547--Nucleotide-binding
KW-0597--Phosphoprotein
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase
Interpro

IPR011992--EF-hand-dom_pair
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS
IPR034672--SIK
IPR015940--UBA
PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS50030--UBA
Pfam

PF00069--Pkinase
SMART

SM00220--S_TKc
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0000287--F:magnesium ion binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0006468--P:protein phosphorylation
KEGG hsa:23387
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ame-011685 Astyanax mexicanus 90.34 5.00e-135 473.00
IUUC-Cja-019739 Callithrix jacchus 91.27 0.00e+00 1843.00
IUUC-Cho-024317 Choloepus hoffmanni 90.92 0.00e+00 1745.00
IUUC-Csv-026013 Ciona savignyi 67.26 2.00e-142 498.00
IUUC-Dre-027537 Danio rerio 70.09 1.00e-174 605.00
IUUC-Dor-030146 Dipodomys ordii 92.03 0.00e+00 1787.00
IUUC-Ete-032889 Echinops telfairi 81.09 0.00e+00 1731.00
IUUC-Eca-033614 Equus caballus 95.06 0.00e+00 2144.00
IUUC-Eeu-035150 Erinaceus europaeus 87.08 0.00e+00 1054.00
IUUC-Gmo-039322 Gadus morhua 67.36 0.00e+00 973.00
IUUC-Gga-041104 Gallus gallus 83.45 0.00e+00 1957.00
IUUC-Gac-042453 Gasterosteus aculeatus 58.23 0.00e+00 1136.00
IUUC-Ggo-044865 Gorilla gorilla 96.97 0.00e+00 1031.00
IUUC-Mcc-054691 Macaca mulatta 98.41 0.00e+00 2303.00
IUUC-Meu-056201 Macropus eugenii 80.19 0.00e+00 1771.00
IUUC-Mmu-064117 Mus musculus 91.64 0.00e+00 2149.00
IUUC-Opr-071103 Ochotona princeps 92.78 0.00e+00 1420.00
IUUC-Oan-072865 Ornithorhynchus anatinus 74.41 0.00e+00 1471.00
IUUC-Ptr-091679 Pan troglodytes 99.84 0.00e+00 2308.00
IUUC-Pab-098094 Pongo abelii 99.60 0.00e+00 2336.00
IUUC-Pca-100633 Procavia capensis 85.78 0.00e+00 1534.00
IUUC-Pva-102747 Pteropus vampyrus 93.59 0.00e+00 2157.00
IUUC-Ssc-115276 Sus scrofa 92.86 0.00e+00 2103.00
IUUC-Tru-117598 Takifugu rubripes 58.05 0.00e+00 1115.00
IUUC-Tsy-118859 Tarsius syrichta 90.57 5.00e-152 532.00
IUUC-Tni-120589 Tetraodon nigroviridis 58.06 0.00e+00 1128.00
IUUC-Tbe-127501 Tupaia belangeri 90.30 0.00e+00 1956.00
IUUC-Ttr-128329 Tursiops truncatus 87.14 0.00e+00 1948.00
IUUC-Vpa-130601 Vicugna pacos 81.61 2.00e-179 623.00
Created Date 25-Jun-2017

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