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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Cel-018194
UUCD1 version UUC-CaE-00500
Ensembl Protein ID EEED8.16
UniProt Accession Q95QN6; BRAP2_CAEEL
Genbank Protein ID CCD68743.1
Protein Name BRCA1-associated protein homolog 2
Genbank Nucleotide ID FO081042
Gene Name brap-2; EEED8.16
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
WBGene00017144 EEED8.16 EEED8.16
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
miRTarBasemicroRNAmiRNAMapRAID2
Protein-protein Interaction
IIDPINAMentha
Post-translational Modifications (PTMs)
dbPAFdbPTMPhospho.ELM
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/RING 3.90e-08 34.0 260 297
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/RING
   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           Ca+Cle+++d +l   C+H fha Cl++w           +CP+Cr
   Q: 260  CAVCLERMDDSVLAILCNHSFHARCLEQW--------ADNTCPVCR 297
           **********999999*************........8889****8 PP
   
Organism Caenorhabditis elegans
Functional Description
(View)

Functional Description


     Controls the stress response to increased levels of reactive oxygen species by modulating the brc-1-dependent expression of cki-1.
 Controls the stress response to increased levels of reactive oxygen species by modulating the brc-1-dependent expression of cki-1.
Protein Sequence
(Fasta)
MSSLYVPLVL RLEVRDRTKI VQSFIDDSKA GSESPLAGER TRQRLVKKGN TPPKKELKGR 60
EEDPPIGVMS SEPSHNYHKG RRTYSEVVIE SLDGEKLVDS SSSVAGTSEK SGGRSVSEGP 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Cel-018194|E3,RING|Caenorhabditis elegans
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GTGTATGAGC AGTCTTTACG TGCCATTAGT TTTACGGCTC GAAGTGAGAG ACCGGACAAA 60
AATCGTGCAA TCTTTTATCG ACGACTCGAA AGCAGGAAGT GAATCCCCAC TGGCAGGTGA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Cel-018194|E3,RING|Caenorhabditis elegans
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0346--Stress response
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR011422--BRAP2
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP
PROSITE

PS50089--ZF_RING_2
PS50271--ZF_UBP
Pfam

PF07576--BRAP2
PF13639--zf-RING_2
PF02148--zf-UBP
SMART

SM00184--RING
SM00290--ZnF_UBP
Gene Ontology

GO:0008270--F:zinc ion binding
KEGG cel:CELE_EEED8.16
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000519 Aegilops tauschii 27.41 5.00e-40 157.00
IUUC-Aml-002229 Ailuropoda melanoleuca 37.61 6.00e-109 386.00
IUUC-Atr-002785 Amborella trichopoda 35.68 2.00e-76 278.00
IUUC-Apl-004048 Anas platyrhynchos 41.12 5.00e-107 380.00
IUUC-Aca-005133 Anolis carolinensis 40.04 1.00e-104 372.00
IUUC-Aly-006306 Arabidopsis lyrata 32.75 3.00e-64 237.00
IUUC-Ath-007604 Arabidopsis thaliana 32.61 2.00e-66 245.00
IUUC-Ago-007905 Ashbya gossypii 31.75 2.00e-60 225.00
IUUC-Acl-008310 Aspergillus clavatus 32.04 7.00e-60 223.00
IUUC-Afl-008497 Aspergillus flavus 31.66 8.00e-52 196.00
IUUC-Afu-008830 Aspergillus fumigatus 35.17 1.00e-57 216.00
IUUC-Ani-009485 Aspergillus nidulans 31.86 5.00e-62 230.00
IUUC-Ang-009603 Aspergillus niger 33.33 2.00e-57 215.00
IUUC-Aor-009935 Aspergillus oryzae 30.57 4.00e-56 211.00
IUUC-Ate-010485 Aspergillus terreus 34.30 3.00e-62 231.00
IUUC-Ame-011516 Astyanax mexicanus 40.38 1.00e-91 328.00
IUUC-Bgr-011985 Blumeria graminis 28.87 2.00e-49 189.00
IUUC-Bta-013203 Bos taurus 37.88 5.00e-110 390.00
IUUC-Bci-013788 Botrytis cinerea 37.07 7.00e-57 214.00
IUUC-Bdi-014763 Brachypodium distachyon 33.89 1.00e-69 256.00
IUUC-Bol-015518 Brassica oleracea 31.53 4.00e-65 241.00
IUUC-Bra-017435 Brassica rapa 31.12 1.00e-65 242.00
IUUC-Cja-018948 Callithrix jacchus 36.44 2.00e-107 381.00
IUUC-Cfa-020377 Canis familiaris 37.16 2.00e-109 388.00
IUUC-Cpo-021930 Cavia porcellus 36.21 8.00e-107 379.00
IUUC-Cre-022571 Chlamydomonas reinhardtii 36.75 4.00e-47 180.00
IUUC-Csa-023554 Chlorocebus sabaeus 37.25 8.00e-96 342.00
IUUC-Cho-025045 Choloepus hoffmanni 31.66 5.00e-29 121.00
IUUC-Cin-025326 Ciona intestinalis 38.54 3.00e-87 314.00
IUUC-Csv-026232 Ciona savignyi 39.02 2.00e-89 321.00
IUUC-Cgl-026587 Colletotrichum gloeosporioides 32.82 3.00e-64 238.00
IUUC-Cne-026980 Cryptococcus neoformans 29.93 2.00e-39 155.00
IUUC-Cme-027262 Cyanidioschyzon merolae 30.69 4.00e-52 198.00
IUUC-Dre-028521 Danio rerio 36.28 6.00e-103 366.00
IUUC-Dno-029291 Dasypus novemcinctus 36.53 4.00e-105 374.00
IUUC-Dor-030231 Dipodomys ordii 33.50 2.00e-92 331.00
IUUC-Dse-031234 Dothistroma septosporum 29.43 5.00e-50 191.00
IUUC-Dme-032095 Drosophila melanogaster 36.18 5.00e-94 337.00
IUUC-Ete-032227 Echinops telfairi 34.47 5.00e-63 234.00
IUUC-Eca-034404 Equus caballus 37.04 3.00e-109 387.00
IUUC-Eeu-035030 Erinaceus europaeus 41.63 9.00e-40 156.00
IUUC-Fca-035428 Felis catus 37.31 2.00e-108 385.00
IUUC-Fal-037435 Ficedula albicollis 39.81 1.00e-107 382.00
IUUC-Fox-037733 Fusarium oxysporum 29.93 6.00e-57 214.00
IUUC-Fso-038427 Fusarium solani 32.51 2.00e-55 209.00
IUUC-Gmo-038817 Gadus morhua 39.06 2.00e-100 358.00
IUUC-Ggr-039949 Gaeumannomyces graminis 30.97 1.00e-55 210.00
IUUC-Gga-040929 Gallus gallus 39.69 7.00e-109 386.00
IUUC-Gac-041893 Gasterosteus aculeatus 36.15 1.00e-100 358.00
IUUC-Gma-043119 Glycine max 31.72 8.00e-68 249.00
IUUC-Ggo-045106 Gorilla gorilla 39.86 3.00e-93 334.00
IUUC-Hsa-045685 Homo sapiens 36.99 2.00e-110 392.00
IUUC-Hvu-047475 Hordeum vulgare 31.65 2.00e-34 137.00
IUUC-Itr-048406 Ictidomys tridecemlineatus 36.72 2.00e-107 381.00
IUUC-Kpa-049175 Komagataella pastoris 33.18 4.00e-63 234.00
IUUC-Lch-050408 Latimeria chalumnae 38.30 5.00e-106 377.00
IUUC-Lpe-050777 Leersia perrieri 31.67 1.00e-58 219.00
IUUC-Loc-052160 Lepisosteus oculatus 30.70 3.00e-67 248.00
IUUC-Lma-053095 Leptosphaeria maculans 32.54 1.00e-66 246.00
IUUC-Laf-053497 Loxodonta africana 37.54 1.00e-107 382.00
IUUC-Mcc-055381 Macaca mulatta 37.16 1.00e-110 392.00
IUUC-Meu-056402 Macropus eugenii 33.33 1.00e-52 199.00
IUUC-Mor-057002 Magnaporthe oryzae 33.19 1.00e-61 229.00
IUUC-Mpo-057508 Magnaporthe poae 35.00 2.00e-52 199.00
IUUC-Mtr-058619 Medicago truncatula 33.18 2.00e-60 225.00
IUUC-Mla-058901 Melampsora laricipopulina 41.67 3.00e-57 215.00
IUUC-Mga-059667 Meleagris gallopavo 42.31 6.00e-107 379.00
IUUC-Mvi-060229 Microbotryum violaceum 28.67 1.00e-52 199.00
IUUC-Mmr-060881 Microcebus murinus 35.79 5.00e-97 347.00
IUUC-Mdo-062573 Monodelphis domestica 36.22 3.00e-102 364.00
IUUC-Mmu-063656 Mus musculus 36.90 3.00e-110 390.00
IUUC-Mac-065512 Musa acuminata 34.71 4.00e-73 267.00
IUUC-Mpu-065816 Mustela putorius furo 37.16 1.00e-108 385.00
IUUC-Mlu-067225 Myotis lucifugus 37.50 2.00e-109 388.00
IUUC-Nfi-068534 Neosartorya fischeri 35.17 9.00e-58 217.00
IUUC-Ncr-068801 Neurospora crassa 29.15 4.00e-59 221.00
IUUC-Nle-069258 Nomascus leucogenys 38.16 1.00e-105 375.00
IUUC-Opr-070877 Ochotona princeps 39.79 3.00e-97 347.00
IUUC-Ont-072141 Oreochromis niloticus 35.51 7.00e-100 356.00
IUUC-Oan-072961 Ornithorhynchus anatinus 38.01 8.00e-107 379.00
IUUC-Ocu-074020 Oryctolagus cuniculus 38.74 6.00e-96 345.00
IUUC-Oba-075084 Oryza barthii 28.85 6.00e-57 213.00
IUUC-Obr-076840 Oryza brachyantha 34.66 1.00e-69 255.00
IUUC-Ogl-077880 Oryza glaberrima 34.90 7.00e-65 239.00
IUUC-Ogu-078968 Oryza glumaepatula 28.66 8.00e-57 213.00
IUUC-Oin-079200 Oryza indica 34.90 8.00e-65 239.00
IUUC-Olo-080753 Oryza longistaminata 30.81 1.00e-53 202.00
IUUC-Ome-081756 Oryza meridionalis 30.70 1.00e-56 213.00
IUUC-Oni-082434 Oryza nivara 28.54 5.00e-57 214.00
IUUC-Opu-083262 Oryza punctata 30.94 4.00e-57 214.00
IUUC-Oru-084381 Oryza rufipogon 28.66 8.00e-57 213.00
IUUC-Osa-085760 Oryza sativa 40.44 7.00e-55 206.00
IUUC-Ola-087390 Oryzias latipes 36.74 1.00e-96 345.00
IUUC-Olu-087694 Ostreococcus lucimarinus 29.06 9.00e-55 206.00
IUUC-Oga-088612 Otolemur garnettii 37.52 3.00e-109 387.00
IUUC-Oar-089988 Ovis aries 37.27 2.00e-107 382.00
IUUC-Ptr-090637 Pan troglodytes 36.99 3.00e-110 391.00
IUUC-Pan-092506 Papio anubis 37.16 1.00e-110 392.00
IUUC-Psi-093026 Pelodiscus sinensis 38.86 9.00e-102 362.00
IUUC-Pno-094779 Phaeosphaeria nodorum 28.34 2.00e-43 168.00
IUUC-Ppa-095731 Physcomitrella patens 34.28 5.00e-75 273.00
IUUC-Pfo-096725 Poecilia formosa 36.05 2.00e-96 345.00
IUUC-Pab-098413 Pongo abelii 42.11 7.00e-84 303.00
IUUC-Pop-099538 Populus trichocarpa 32.48 1.00e-65 242.00
IUUC-Pca-100130 Procavia capensis 42.47 5.00e-83 300.00
IUUC-Ppe-101843 Prunus persica 32.76 4.00e-72 263.00
IUUC-Pva-102752 Pteropus vampyrus 40.32 3.00e-106 377.00
IUUC-Pgr-103478 Puccinia graminis 34.42 2.00e-61 229.00
IUUC-Ptt-103921 Puccinia triticina 36.27 3.00e-60 225.00
IUUC-Pte-104032 Pyrenophora teres 31.91 2.00e-62 232.00
IUUC-Pyt-104480 Pyrenophora triticirepentis 31.71 9.00e-62 230.00
IUUC-Rno-106037 Rattus norvegicus 35.36 5.00e-85 307.00
IUUC-Sce-106310 Saccharomyces cerevisiae 29.18 2.00e-49 188.00
IUUC-Sha-106752 Sarcophilus harrisii 38.80 9.00e-105 372.00
IUUC-Sja-107665 Schizosaccharomyces japonicus 33.18 8.00e-68 249.00
IUUC-Spo-108042 Schizosaccharomyces pombe 34.64 5.00e-64 237.00
IUUC-Ssl-108504 Sclerotinia sclerotiorum 34.99 8.00e-57 214.00
IUUC-Smo-109399 Selaginella moellendorffii 34.60 7.00e-75 273.00
IUUC-Sit-110251 Setaria italica 33.91 8.00e-70 256.00
IUUC-Sly-111563 Solanum lycopersicum 34.23 9.00e-66 242.00
IUUC-Stu-112294 Solanum tuberosum 34.92 4.00e-71 260.00
IUUC-Sar-113080 Sorex araneus 56.44 2.00e-36 144.00
IUUC-Sbi-113915 Sorghum bicolor 34.06 1.00e-68 252.00
IUUC-Sre-114897 Sporisorium reilianum 36.18 2.00e-53 202.00
IUUC-Ssc-115369 Sus scrofa 56.90 8.00e-60 221.00
IUUC-Tgu-116710 Taeniopygia guttata 39.96 5.00e-110 390.00
IUUC-Tru-117941 Takifugu rubripes 35.08 3.00e-102 364.00
IUUC-Tsy-118902 Tarsius syrichta 37.26 1.00e-41 162.00
IUUC-Tni-120587 Tetraodon nigroviridis 35.92 4.00e-104 370.00
IUUC-Tca-121425 Theobroma cacao 33.33 1.00e-69 256.00
IUUC-Tre-121874 Trichoderma reesei 31.02 3.00e-59 221.00
IUUC-Tvi-122266 Trichoderma virens 36.60 5.00e-57 214.00
IUUC-Tae-124194 Triticum aestivum 34.78 2.00e-66 245.00
IUUC-Tur-126467 Triticum urartu 32.65 6.00e-45 173.00
IUUC-Tme-127096 Tuber melanosporum 33.20 6.00e-57 213.00
IUUC-Tbe-128012 Tupaia belangeri 40.38 4.00e-97 347.00
IUUC-Ttr-128388 Tursiops truncatus 37.16 5.00e-108 383.00
IUUC-Uma-129610 Ustilago maydis 27.94 1.00e-51 197.00
IUUC-Vda-129830 Verticillium dahliae 29.74 1.00e-59 223.00
IUUC-Vpa-130171 Vicugna pacos 37.90 7.00e-110 389.00
IUUC-Vvi-131063 Vitis vinifera 38.74 9.00e-65 239.00
IUUC-Xtr-132313 Xenopus tropicalis 39.42 2.00e-106 378.00
IUUC-Xma-133303 Xiphophorus maculatus 36.22 4.00e-97 347.00
IUUC-Yli-134669 Yarrowia lipolytica 31.78 1.00e-56 212.00
IUUC-Zma-135783 Zea mays 34.28 5.00e-68 250.00
Created Date 25-Jun-2017

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