iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Spo-108036

Ensembl Protein ID

SPBC21.04.1:pep

UniProt Accession

O94646; MED8_SCHPO

Genbank Protein ID

CAB36884.1

Protein Name

Mediator of RNA polymerase II transcription subunit 8; Cell separation protein sep15; Mediator complex subunit 8

Genbank Nucleotide ID

AF093755

Gene Name

med8; sep15; SPBC21.04

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
SPBC21.04	SPBC21.04.1	SPBC21.04.1:pep

Annotation

mRNA Expression
GEO
Protein-protein Interaction
iRefIndex	HINT	Mentha
Protein 3D Structure
PDB	MMDB
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	28.81	1.80e-02	37.00	IUUC-Hsa-046908

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Schizosaccharomyces pombe

Functional Description
(View)

Component of the Mediator complex.

Protein Sequence
(Fasta)

MEDISTEKTV ESLEAIRHRI AQIVQSLTHF LAILHQSESL SPWPTIHKNF NILLSQIHSL 60
SNNLAAHSHT LQTTSIYPSL EFPVKEQEPL LTTLLRTKAL PEVEEWEANT LQEYEASISS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAATAACCAT GTATACATTA AACAGCTGGA ACGTATTTTC TAAAACGTTT ACGAACTCAT 60
ATTATTCTGC CTTAAGTAAA ATATGAGGTA TTGCATACCA CGAACACACA TATGAATTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0002--3D-structure
KW-0010--Activator
KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation

Interpro

IPR020178--Mediatior_Med8_fun
IPR019364--Mediatior_Med8_fun/met

Pfam

PF10232--Med8

Gene Ontology

GO:0005829--C:cytosol
GO:0016592--C:mediator complex
GO:0005634--C:nucleus
GO:0030295--F:protein kinase activator activity
GO:0001104--F:RNA polymerase II transcription cofactor activity
GO:0034613--P:cellular protein localization
GO:0006351--P:transcription, DNA-templated

KEGG

spo:SPBC21.04

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001562	Ailuropoda melanoleuca	28.81	8.00e-04	35.40
IUUC-Apl-004218	Anas platyrhynchos	30.51	2.00e-04	37.40
IUUC-Aca-005363	Anolis carolinensis	32.20	1.00e-05	42.00
IUUC-Ame-011384	Astyanax mexicanus	29.66	3.00e-03	33.50
IUUC-Bta-012751	Bos taurus	28.81	8.00e-04	35.40
IUUC-Cja-019318	Callithrix jacchus	28.81	2.00e-03	34.30
IUUC-Cpo-022416	Cavia porcellus	27.55	2.80e-01	26.90
IUUC-Csa-023695	Chlorocebus sabaeus	28.81	5.00e-04	36.60
IUUC-Cin-025570	Ciona intestinalis	31.15	7.00e-03	32.00
IUUC-Csv-025808	Ciona savignyi	29.17	9.00e-03	31.60
IUUC-Dre-027606	Danio rerio	29.66	2.00e-04	36.20
IUUC-Dno-029924	Dasypus novemcinctus	27.55	2.00e-01	27.30
IUUC-Dor-030115	Dipodomys ordii	28.81	8.00e-04	35.40
IUUC-Eca-034101	Equus caballus	28.81	9.00e-04	35.40
IUUC-Fca-036172	Felis catus	28.81	1.00e-03	35.40
IUUC-Fal-036877	Ficedula albicollis	30.51	3.00e-04	37.00
IUUC-Gmo-039244	Gadus morhua	27.12	8.10e-02	28.50
IUUC-Gga-040751	Gallus gallus	30.51	2.00e-04	37.40
IUUC-Gac-041885	Gasterosteus aculeatus	27.97	2.00e-03	33.90
IUUC-Ggo-045201	Gorilla gorilla	28.81	4.00e-04	36.60
IUUC-Hsa-046908	Homo sapiens	28.81	4.00e-04	36.60
IUUC-Itr-048814	Ictidomys tridecemlineatus	28.81	9.00e-04	35.40
IUUC-Loc-051765	Lepisosteus oculatus	31.36	2.00e-04	37.40
IUUC-Laf-053336	Loxodonta africana	27.55	1.00e-01	28.50
IUUC-Mcc-055259	Macaca mulatta	28.81	4.00e-04	36.60
IUUC-Meu-056166	Macropus eugenii	29.66	1.00e-04	38.50
IUUC-Mga-059317	Meleagris gallopavo	30.51	2.00e-04	37.40
IUUC-Mmr-061501	Microcebus murinus	28.81	2.00e-03	34.70
IUUC-Mdo-062026	Monodelphis domestica	29.66	1.00e-04	37.70
IUUC-Mmu-063469	Mus musculus	28.81	6.00e-04	35.80
IUUC-Mpu-065945	Mustela putorius furo	28.81	9.00e-04	35.40
IUUC-Mlu-067414	Myotis lucifugus	28.81	1.00e-03	35.00
IUUC-Nle-069411	Nomascus leucogenys	28.81	5.00e-04	36.60
IUUC-Opr-070733	Ochotona princeps	29.66	6.00e-04	36.20
IUUC-Ont-071344	Oreochromis niloticus	27.97	3.00e-03	33.50
IUUC-Oan-073366	Ornithorhynchus anatinus	28.81	6.00e-04	35.80
IUUC-Ocu-074762	Oryctolagus cuniculus	28.81	7.00e-04	35.40
IUUC-Osa-086248	Oryza sativa	37.50	3.20e+00	24.60
IUUC-Ola-086874	Oryzias latipes	27.97	2.00e-03	33.90
IUUC-Oga-088187	Otolemur garnettii	28.81	8.00e-04	35.40
IUUC-Oar-089832	Ovis aries	28.81	8.00e-04	35.40
IUUC-Ptr-091178	Pan troglodytes	29.66	9.00e-05	38.90
IUUC-Pan-092520	Papio anubis	28.81	2.00e-04	37.70
IUUC-Psi-093517	Pelodiscus sinensis	30.51	2.00e-04	37.40
IUUC-Pfo-097258	Poecilia formosa	40.00	3.10e-01	28.90
IUUC-Pva-102173	Pteropus vampyrus	28.81	1.00e-03	34.70
IUUC-Ptt-103935	Puccinia triticina	24.44	9.40e-01	25.40
IUUC-Sar-113363	Sorex araneus	26.79	5.00e-04	36.20
IUUC-Ssc-115563	Sus scrofa	28.81	7.00e-04	35.80
IUUC-Tgu-116686	Taeniopygia guttata	30.51	4.00e-04	36.60
IUUC-Tru-118003	Takifugu rubripes	28.81	2.00e-03	34.30
IUUC-Tsy-118875	Tarsius syrichta	28.81	1.00e-03	34.70
IUUC-Tni-120624	Tetraodon nigroviridis	28.81	1.00e-03	35.00
IUUC-Ttr-129198	Tursiops truncatus	28.81	1.00e-03	34.70
IUUC-Xtr-132397	Xenopus tropicalis	28.12	1.00e-03	35.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence