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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Dme-032157
Ensembl Protein ID FBpp0088428
UniProt Accession Q24246; O96508; O96510; O96511; O96512; O96513; O96514; O96515; O96516; Q5U0Z1; Q86BQ5; Q9NG49; Q9TZR7; Q9TZR8; Q9TZR9; Q9TZS0; Q9VR78; DYIN_DROME
Genbank Protein ID AAC78306.1; AAC70933.1; AAC70934.1; AAC70935.1; AAC70936.1; AAC70937.1; AAC70938.1; AAC70939.1; AAC70940.1; AAC70941.1; AAC70942.1; AAC70943.1; AAF73046.1; AAF50928.2; AAN09553.1; AAN09554.1; AAN09555.1; AAN09556.1; AAN09557.1; AAN09558.1; AAN09559.1; AAN09560.1; AAN09561.1; AAN09562.1; AAV36986.1; AAB51185.1
Protein Name Cytoplasmic dynein 1 intermediate chain; Dynein intermediate chain, cytosolic; Protein short wing
Genbank Nucleotide ID AF070687; AF070689; AF070690; AF070691; AF070692; AF070693; AF070694; AF070695; AF070696; AF070697; AF070698; AF070699; AF263371; AE014298; AE014298; AE014298; AE014298; AE014298; AE014298; AE014298; AE014298; AE014298; AE014298; AE014298; BT016101; L41945
Gene Name sw; Cdic; Dic19B; CG18000
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
FBgn0003654 FBtr0089407 FBpp0088429
FBgn0003654 FBtr0089401 FBpp0088423
FBgn0003654 FBtr0340360 FBpp0309318
FBgn0003654 FBtr0089400 FBpp0088422
FBgn0003654 FBtr0089398 FBpp0088420
FBgn0003654 FBtr0089405 FBpp0088427
FBgn0003654 FBtr0089403 FBpp0088425
FBgn0003654 FBtr0089402 FBpp0088424
FBgn0003654 FBtr0089404 FBpp0088426
FBgn0003654 FBtr0089399 FBpp0088421
FBgn0003654 FBtr0340361 FBpp0309319
FBgn0003654 FBtr0089406 FBpp0088428
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpress
DNA & RNA Element
microRNARAID2
Protein-protein Interaction
IIDiRefIndexPINAMentha
Protein 3D Structure
PDBMMDB
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 1.40e-15 56.8 372 397
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 9    laf....sdtllvsGsdDgtikvWDlr 31
            +f    + +l++ G++ g+i +WD r
   Q: 372  TCFakfnP-NLILGGTYSGQIVLWDNR 397
           44555343.9***************65 PP
   
Organism Drosophila melanogaster
Functional Description
(View)

Functional Description


     Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the help dynein bind to dynactin 150 kDa component (By similarity).
 Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the help dynein bind to dynactin 150 kDa component (By similarity).
Protein Sequence
(Fasta)
MDRKAELERK KAKLAALREE KDRRRREKEI KDMEEAAGRI GGGAGIDKDQ RKDLDEMLSS 60
LGVAPVSEVL SSLSSVNSMT SDNSNTQTPD ASLQATVNGQ SGGKKQPLNL SVYNVQATNI 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Dme-032157|E3,WD_repeat|Drosophila melanogaster
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Nucleotide Sequence
(Fasta)
TGTTCACAGC TATCGCCGTA CAGTAGTAAA ATCTTATTCT TGTGTTTAAA CTTGTGTTAA 60
TTAAGAATTC GGAATCCCGC TAAGAATCCT AGTCTTCCAC ACCCTTTGGG CATCTATGTA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Dme-032157|E3,WD_repeat|Drosophila melanogaster
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0002--3D-structure
KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0243--Dynein
KW-0458--Lysosome
KW-0472--Membrane
KW-0493--Microtubule
KW-0505--Motor protein
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0813--Transport
KW-0853--WD repeat
Interpro

IPR025956--DYNC1I1/DYNC1I2
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF11540--Dynein_IC2
SMART

SM00320--WD40
Gene Ontology

GO:0005868--C:cytoplasmic dynein complex
GO:0005765--C:lysosomal membrane
GO:0005874--C:microtubule
GO:0005875--C:microtubule associated complex
GO:0043005--C:neuron projection
GO:0031965--C:nuclear membrane
GO:0034452--F:dynactin binding
GO:0045504--F:dynein heavy chain binding
GO:0045503--F:dynein light chain binding
GO:0003774--F:motor activity
GO:0008088--P:axo-dendritic transport
GO:0007349--P:cellularization
GO:0051642--P:centrosome localization
GO:0001754--P:eye photoreceptor cell differentiation
GO:0000226--P:microtubule cytoskeleton organization
GO:0007018--P:microtubule-based movement
GO:0034501--P:protein localization to kinetochore
GO:0007291--P:sperm individualization
GO:0007051--P:spindle organization
KEGG dme:Dmel_CG18000
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002108 Ailuropoda melanoleuca 62.65 2.00e-168 585.00
IUUC-Apl-003265 Anas platyrhynchos 63.39 8.00e-165 572.00
IUUC-Aca-004911 Anolis carolinensis 63.92 2.00e-170 591.00
IUUC-Acl-008245 Aspergillus clavatus 37.31 3.00e-77 282.00
IUUC-Afu-009032 Aspergillus fumigatus 36.02 2.00e-76 279.00
IUUC-Ani-009498 Aspergillus nidulans 37.24 1.00e-82 300.00
IUUC-Ame-011786 Astyanax mexicanus 62.39 1.00e-168 585.00
IUUC-Bta-013557 Bos taurus 62.27 8.00e-169 586.00
IUUC-Cel-018207 Caenorhabditis elegans 44.42 1.00e-98 353.00
IUUC-Cho-025102 Choloepus hoffmanni 51.62 2.00e-128 452.00
IUUC-Cne-026971 Cryptococcus neoformans 45.31 2.00e-108 385.00
IUUC-Dre-028465 Danio rerio 63.61 2.00e-168 585.00
IUUC-Dor-030613 Dipodomys ordii 62.27 3.00e-168 584.00
IUUC-Dse-031518 Dothistroma septosporum 36.45 8.00e-72 264.00
IUUC-Ete-032322 Echinops telfairi 54.92 9.00e-143 499.00
IUUC-Eca-033654 Equus caballus 62.80 7.00e-170 589.00
IUUC-Fca-035962 Felis catus 62.65 2.00e-168 585.00
IUUC-Fal-037591 Ficedula albicollis 63.46 2.00e-165 575.00
IUUC-Fox-037992 Fusarium oxysporum 37.50 7.00e-84 304.00
IUUC-Fso-038209 Fusarium solani 37.30 4.00e-81 295.00
IUUC-Gga-040996 Gallus gallus 63.46 3.00e-165 574.00
IUUC-Itr-048711 Ictidomys tridecemlineatus 63.03 3.00e-170 591.00
IUUC-Lch-050416 Latimeria chalumnae 63.33 5.00e-167 580.00
IUUC-Loc-051856 Lepisosteus oculatus 64.02 7.00e-164 569.00
IUUC-Lma-052957 Leptosphaeria maculans 31.22 7.00e-59 221.00
IUUC-Laf-054418 Loxodonta africana 62.44 2.00e-170 591.00
IUUC-Meu-056899 Macropus eugenii 63.20 7.00e-167 579.00
IUUC-Mor-056924 Magnaporthe oryzae 39.39 2.00e-92 332.00
IUUC-Mga-060055 Meleagris gallopavo 63.46 2.00e-165 575.00
IUUC-Mvi-060541 Microbotryum violaceum 41.44 2.00e-101 362.00
IUUC-Mdo-061887 Monodelphis domestica 63.79 1.00e-166 578.00
IUUC-Mpu-065831 Mustela putorius furo 63.68 2.00e-168 585.00
IUUC-Mlu-066987 Myotis lucifugus 63.29 2.00e-167 582.00
IUUC-Nfi-068441 Neosartorya fischeri 36.13 6.00e-77 281.00
IUUC-Opr-070509 Ochotona princeps 62.23 2.00e-164 571.00
IUUC-Ont-071319 Oreochromis niloticus 63.27 8.00e-169 586.00
IUUC-Oan-073420 Ornithorhynchus anatinus 63.55 6.00e-166 576.00
IUUC-Ola-086484 Oryzias latipes 63.74 3.00e-171 594.00
IUUC-Oar-090204 Ovis aries 62.80 3.00e-170 591.00
IUUC-Psi-092969 Pelodiscus sinensis 62.65 3.00e-169 587.00
IUUC-Pno-095122 Phaeosphaeria nodorum 35.56 5.00e-76 278.00
IUUC-Pfo-097067 Poecilia formosa 62.89 6.00e-166 576.00
IUUC-Pca-100827 Procavia capensis 64.07 8.00e-122 430.00
IUUC-Pva-102223 Pteropus vampyrus 62.50 8.00e-169 586.00
IUUC-Ptt-103792 Puccinia triticina 40.45 1.00e-101 363.00
IUUC-Pte-104046 Pyrenophora teres 35.52 5.00e-73 268.00
IUUC-Pyt-104796 Pyrenophora triticirepentis 36.38 1.00e-70 260.00
IUUC-Rno-105916 Rattus norvegicus 62.07 6.00e-173 600.00
IUUC-Sha-107044 Sarcophilus harrisii 63.79 7.00e-167 579.00
IUUC-Tgu-116477 Taeniopygia guttata 63.46 6.00e-165 573.00
IUUC-Tru-117872 Takifugu rubripes 62.89 2.00e-164 572.00
IUUC-Tni-120754 Tetraodon nigroviridis 61.52 1.00e-166 579.00
IUUC-Tvi-122391 Trichoderma virens 37.61 2.00e-84 306.00
IUUC-Tbe-127693 Tupaia belangeri 56.97 9.00e-118 416.00
IUUC-Ttr-129188 Tursiops truncatus 62.27 1.00e-168 585.00
Created Date 25-Jun-2017

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