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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Hsa-046109
Ensembl Protein ID ENSP00000362763.3
UniProt Accession Q15916; A8K8N6; ZBTB6_HUMAN
Genbank Protein ID CAA57543.1; BAF85090.1; EAW87552.1; AAH37282.1
Protein Name Zinc finger and BTB domain-containing protein 6; Zinc finger protein 482; Zinc finger protein with interaction domain
Genbank Nucleotide ID X82018; AK292401; CH471090; BC037282
Gene Name ZBTB6; ZID; ZNF482
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000186130.4 ENST00000373659.3 ENSP00000362763.3
Annotation
Cancer Mutation
TCGAICGCCOSMICCGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressTCGAICGC
COSMICTHPAHPM
DNA & RNA Element
UTRdbAREsiteCircNetmiRTarBase
microRNATRANSFACTargetScanRepTar
SomamiRmiRcodeRAID2
Protein-protein Interaction
IIDiRefIndexPINAHINT
MenthaInWeb_IM
Disease-associated Variation
OMIM
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusUniProt
BioGRID
DNA Methylation
TCGAICGC
Protein Expression/Proteomics
THPAHPMGPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB 9.10e-07 30.8 33 95
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/BCR/BTB_Other: BTB
   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           +Dv ++++++ef+ hk++Laa+S ++++ fl  l +sk + +++i   ++ev r ll  +Ytg l+ 
   Q: 33   CDVSIYINDTEFQGHKVILAACSTFMRDQFL--LTQSK-HVRITIL-QSAEVGRKLLLSCYTGALEV 95
           8*****************************5..56777.7788888.89999999999999999876 PP
   
Organism Homo sapiens
Functional Description
(View)

Functional Description


     Widely expressed with highest levels in brain.
 Widely expressed with highest levels in brain.
Protein Sequence
(Fasta)
MAAESDVLHF QFEQQGDVVL QKMNLLRQQN LFCDVSIYIN DTEFQGHKVI LAACSTFMRD 60
QFLLTQSKHV RITILQSAEV GRKLLLSCYT GALEVKRKEL LKYLTAASYL QMVHIVEKCT 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Hsa-046109|E3,BTB_Other|Homo sapiens
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GTGTTTTCTT CCAGGCTAAG TCCATCTTCC GGCTTGGGCA GACGCTGCCG CGGAATCCTT 60
GACTCTAGTT TTCTGAGTCG GTGAGTGAGT GCAAAGTAGA TTCCTCAGGT GGAGGGTGCC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Hsa-046109|E3,BTB_Other|Homo sapiens
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR000210--BTB/POZ_dom
IPR011333--SKP1/BTB/POZ
IPR013087--Znf_C2H2_type
PROSITE

PS50097--BTB
PS00028--ZINC_FINGER_C2H2_1
PS50157--ZINC_FINGER_C2H2_2
Pfam

PF00651--BTB
SMART

SM00225--BTB
SM00355--ZnF_C2H2
Gene Ontology

GO:0005739--C:mitochondrion
GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0046872--F:metal ion binding
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated
KEGG hsa:10773
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ame-011016 Astyanax mexicanus 52.89 9.00e-32 131.00
IUUC-Bta-012441 Bos taurus 94.58 0.00e+00 832.00
IUUC-Cja-019851 Callithrix jacchus 98.35 0.00e+00 863.00
IUUC-Cfa-020328 Canis familiaris 95.99 0.00e+00 843.00
IUUC-Cpo-022027 Cavia porcellus 94.10 0.00e+00 822.00
IUUC-Csa-024130 Chlorocebus sabaeus 99.29 0.00e+00 872.00
IUUC-Cho-024568 Choloepus hoffmanni 95.05 0.00e+00 811.00
IUUC-Dno-029716 Dasypus novemcinctus 95.23 0.00e+00 790.00
IUUC-Ete-032272 Echinops telfairi 91.75 0.00e+00 807.00
IUUC-Eca-033644 Equus caballus 95.99 0.00e+00 840.00
IUUC-Eeu-034904 Erinaceus europaeus 93.16 0.00e+00 819.00
IUUC-Fal-036710 Ficedula albicollis 76.28 0.00e+00 637.00
IUUC-Gmo-039610 Gadus morhua 52.03 2.00e-27 116.00
IUUC-Ggo-044541 Gorilla gorilla 100.00 0.00e+00 878.00
IUUC-Itr-048653 Ictidomys tridecemlineatus 94.10 0.00e+00 830.00
IUUC-Loc-052329 Lepisosteus oculatus 36.96 8.00e-77 280.00
IUUC-Laf-053344 Loxodonta africana 93.40 0.00e+00 821.00
IUUC-Mcc-055428 Macaca mulatta 99.06 0.00e+00 869.00
IUUC-Meu-055915 Macropus eugenii 79.58 6.00e-112 396.00
IUUC-Mmr-061556 Microcebus murinus 97.41 0.00e+00 858.00
IUUC-Mmu-063464 Mus musculus 92.45 0.00e+00 810.00
IUUC-Mlu-067440 Myotis lucifugus 94.66 0.00e+00 808.00
IUUC-Nle-069279 Nomascus leucogenys 100.00 0.00e+00 878.00
IUUC-Ont-071841 Oreochromis niloticus 33.41 3.00e-54 206.00
IUUC-Oga-088944 Otolemur garnettii 95.75 0.00e+00 838.00
IUUC-Oar-090101 Ovis aries 93.63 0.00e+00 829.00
IUUC-Ptr-091369 Pan troglodytes 100.00 0.00e+00 878.00
IUUC-Pan-092903 Papio anubis 99.06 0.00e+00 870.00
IUUC-Psi-093807 Pelodiscus sinensis 78.93 0.00e+00 664.00
IUUC-Pfo-096344 Poecilia formosa 48.84 6.00e-31 129.00
IUUC-Pab-097901 Pongo abelii 99.76 0.00e+00 875.00
IUUC-Pva-102743 Pteropus vampyrus 94.34 0.00e+00 816.00
IUUC-Rno-104922 Rattus norvegicus 90.09 0.00e+00 790.00
IUUC-Sar-113512 Sorex araneus 91.27 0.00e+00 797.00
IUUC-Ssc-116018 Sus scrofa 91.27 0.00e+00 793.00
IUUC-Tgu-117513 Taeniopygia guttata 77.22 0.00e+00 634.00
IUUC-Tsy-119311 Tarsius syrichta 96.99 0.00e+00 734.00
IUUC-Tni-120696 Tetraodon nigroviridis 52.00 2.00e-31 130.00
IUUC-Ttr-128586 Tursiops truncatus 95.05 0.00e+00 835.00
IUUC-Vpa-130665 Vicugna pacos 93.38 0.00e+00 817.00
Created Date 25-Jun-2017

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