iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

mRNA Expression
GEO
Protein-protein Interaction
IID	iRefIndex	HINT	Mentha
Protein 3D Structure
PDB	MMDB
Post-translational Modifications (PTMs)
CPLM	dbPAF	dbPTM	UniProt
PHOSIDA	BioGRID
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	6.20e-15	53.4	404	458

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           k  +ly++ ++++++L ++kGdv+++++k +  ++W+ g    +g++G+fP+n+ve 
   Q: 404  KAVALYSFAGEESGDLPFRKGDVITILKKSDSQNDWWTG--RVNGREGIFPANYVEL 458
           6679***********************************..8*************86 PP

Organism

Saccharomyces cerevisiae

Protein Sequence
(Fasta)

MGINNPIPRS LKSETKKAAK ILASFVKPNQ VFGADQVIPP DVLKRAKGLA IITILKAGFL 60
FSGRAGSGVI VARLKDGTWS APSAIAMAGA GAGGMVGIEL TDFVFILNTQ DAVKSFSEFG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGTATTA ACAATCCTAT TCCAAGGAGT TTAAAGAGTG AGACAAAGTA TGTTTTATAC 60
GGGTTTGGCT GGGAAACCTT TAAAAAAGTT CTCCCTTAAT TTGTTCATCA TTTACTAACT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0002--3D-structure
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR001452--SH3_domain
IPR033643--SYLF_SH3YL1-like
IPR007461--Ysc84_actin-binding

PROSITE

PS50002--SH3

Pfam

PF00018--SH3_1
PF04366--Ysc84

PRINTS

PR00452--SH3DOMAIN

SMART

SM00326--SH3

Gene Ontology

GO:0030479--C:actin cortical patch
GO:0032587--C:ruffle membrane
GO:0051015--F:actin filament binding
GO:0035091--F:phosphatidylinositol binding
GO:0051666--P:actin cortical patch localization
GO:0051017--P:actin filament bundle assembly
GO:1900027--P:regulation of ruffle assembly

KEGG

sce:YFR024C-A

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003909	Anas platyrhynchos	51.85	4.00e-13	67.00
IUUC-Ago-007765	Ashbya gossypii	80.36	7.00e-81	291.00
IUUC-Ame-011024	Astyanax mexicanus	48.43	3.00e-33	133.00
IUUC-Dme-031741	Drosophila melanogaster	40.23	6.00e-13	65.50
IUUC-Fal-037364	Ficedula albicollis	51.85	3.00e-13	67.40
IUUC-Mpo-057361	Magnaporthe poae	51.85	4.00e-13	65.10

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence