• HOME
  • BROWSE
  • SEARCH
  • LINK
  • DOWNLOAD
  • USER GUIDE
  • Protein
  • Gene
  • Annotation
  • Details
  • Classification
  • Domain Profile
  • Function
  • Protein Sequence
  • Nucleotide Sequence
  • Keyword
  • GO
  • Orthology
  • TOP

Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Hsa-046127
UUCD1 version UUC-HoS-00144
Ensembl Protein ID ENSP00000366953.3
UniProt Accession Q5QP82; A4VCJ5; Q32NE2; Q8N2Q5; Q96ET5; Q9BTQ5; Q9H5P6; DCA10_HUMAN
Genbank Protein ID CAI13878.1; EAW58263.1; AAH03520.2; AAH11959.2; AAI08687.1; AAI39835.1; BAB15574.1; BAC11043.1
Protein Name DDB1- and CUL4-associated factor 10; WD repeat-containing protein 32
Genbank Nucleotide ID AL138752; CH471071; BC003520; BC011959; BC108686; BC139834; AK026854; AK074532
Gene Name DCAF10; WDR32
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000122741.15 ENST00000377724.7 ENSP00000366953.3
ENSG00000122741.15 ENST00000242323.8 ENSP00000242323.8
Annotation
Cancer Mutation
TCGAICGCCOSMICCGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressTCGAICGC
COSMICTHPAHPM
DNA & RNA Element
UTRdbAREsitecircBasecircRNADb
CircNetmiRTarBasemicroRNATRANSFAC
RepTarmiRcodeRAID2
Protein-protein Interaction
IIDiRefIndexPINAHINT
MenthaInWeb_IM
Disease-associated Information
GWASdb
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusdbPTM
HPRDUniProtBioGRIDmUbiSiDa
DNA Methylation
TCGAICGC
Protein Expression/Proteomics
THPAHPMGPMDB
Status Reviewed
Details
Family Domain References (PMIDs)
E3 adaptor/Cullin RING/DCX/DWD WD_repeat 17588513
Classification
Family E-value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 3.00e-15 57.4 210 241
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 2    Htdsvtclaf.sdtllvsGsdDgtikvWDlrt 32
           H+d v+ ++f +++l++++sdD ti +WDlr+
   Q: 210  HEDCVNNIRFlDNRLFATCSDDTTIALWDLRK 241
           9*********7669***************986 PP
   
Organism Homo sapiens
Functional Description
(View)

Functional Description


     May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.
 May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.
Protein Sequence
(Fasta)
MFPFGPHSPG GDGSAGAGAE EPTPHEGQAA ATGPPSPLHP GADATHPPPP ARSPRRPGAP 60
SLSPAPRSGE LGLPGAPESS TASAPGEPSP PSPPCRRPGP DCRAKSRGRH GLGAGLGGPG 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Hsa-046127|E3,WD_repeat|Homo sapiens
Please wait for a moment...
Nucleotide Sequence
(Fasta)
AAAGTGGAGA CACCAGTACA TACTCAGCCT CACAGGACTG ACTGGTCAGG CCACTCATCC 60
CCAGGCACGC GGCCACCGGT CACTGACAAC TACAGACCGA CTCTGCCACC CAGATCAGGT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Hsa-046127|E3,WD_repeat|Homo sapiens
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0488--Methylation
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0833--Ubl conjugation pathway
KW-0853--WD repeat
Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF00400--WD40
SMART

SM00320--WD40
Gene Ontology

GO:0080008--C:Cul4-RING E3 ubiquitin ligase complex
GO:0016567--P:protein ubiquitination
KEGG hsa:79269
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002004 Ailuropoda melanoleuca 91.63 0.00e+00 739.00
IUUC-Apl-003942 Anas platyrhynchos 89.54 0.00e+00 672.00
IUUC-Aca-005259 Anolis carolinensis 84.93 0.00e+00 734.00
IUUC-Ame-010936 Astyanax mexicanus 79.04 0.00e+00 694.00
IUUC-Bta-012820 Bos taurus 89.74 0.00e+00 810.00
IUUC-Cja-019380 Callithrix jacchus 95.53 0.00e+00 894.00
IUUC-Cfa-021136 Canis familiaris 91.95 0.00e+00 779.00
IUUC-Cpo-021784 Cavia porcellus 91.09 0.00e+00 778.00
IUUC-Csa-024250 Chlorocebus sabaeus 98.03 0.00e+00 905.00
IUUC-Cin-025712 Ciona intestinalis 43.71 7.00e-37 147.00
IUUC-Csv-025985 Ciona savignyi 38.73 1.00e-34 139.00
IUUC-Dre-027652 Danio rerio 78.36 0.00e+00 689.00
IUUC-Dno-030060 Dasypus novemcinctus 96.32 0.00e+00 701.00
IUUC-Dme-031950 Drosophila melanogaster 35.96 2.00e-48 187.00
IUUC-Ete-032379 Echinops telfairi 82.89 7.00e-163 566.00
IUUC-Eca-034313 Equus caballus 94.47 0.00e+00 696.00
IUUC-Fca-036273 Felis catus 93.78 0.00e+00 790.00
IUUC-Fal-037620 Ficedula albicollis 89.92 0.00e+00 672.00
IUUC-Gmo-038647 Gadus morhua 77.16 6.00e-164 570.00
IUUC-Gga-040735 Gallus gallus 90.53 0.00e+00 669.00
IUUC-Gac-041703 Gasterosteus aculeatus 78.68 0.00e+00 693.00
IUUC-Ggo-045268 Gorilla gorilla 99.46 0.00e+00 894.00
IUUC-Itr-048027 Ictidomys tridecemlineatus 95.04 5.00e-172 597.00
IUUC-Lch-050191 Latimeria chalumnae 88.28 0.00e+00 770.00
IUUC-Loc-052006 Lepisosteus oculatus 83.52 0.00e+00 733.00
IUUC-Laf-053546 Loxodonta africana 94.13 0.00e+00 820.00
IUUC-Mcc-055391 Macaca mulatta 100.00 0.00e+00 724.00
IUUC-Meu-056599 Macropus eugenii 91.67 5.00e-102 364.00
IUUC-Mga-059625 Meleagris gallopavo 90.14 5.00e-100 356.00
IUUC-Mmr-061695 Microcebus murinus 94.59 0.00e+00 835.00
IUUC-Mdo-062960 Monodelphis domestica 92.92 0.00e+00 796.00
IUUC-Mmu-063543 Mus musculus 84.63 0.00e+00 815.00
IUUC-Mpu-066132 Mustela putorius furo 84.07 0.00e+00 783.00
IUUC-Mlu-067070 Myotis lucifugus 94.74 0.00e+00 655.00
IUUC-Nle-069325 Nomascus leucogenys 100.00 0.00e+00 724.00
IUUC-Opr-070537 Ochotona princeps 78.42 3.00e-156 545.00
IUUC-Ont-072184 Oreochromis niloticus 80.18 0.00e+00 710.00
IUUC-Oan-072696 Ornithorhynchus anatinus 84.58 0.00e+00 682.00
IUUC-Ocu-074877 Oryctolagus cuniculus 94.39 0.00e+00 851.00
IUUC-Ola-086632 Oryzias latipes 80.52 0.00e+00 630.00
IUUC-Oga-088050 Otolemur garnettii 94.32 0.00e+00 796.00
IUUC-Oar-089358 Ovis aries 79.60 0.00e+00 709.00
IUUC-Ptr-091497 Pan troglodytes 99.82 0.00e+00 875.00
IUUC-Pan-092813 Papio anubis 98.48 0.00e+00 875.00
IUUC-Psi-093404 Pelodiscus sinensis 91.58 0.00e+00 675.00
IUUC-Pfo-097103 Poecilia formosa 80.68 0.00e+00 706.00
IUUC-Pab-098099 Pongo abelii 98.57 0.00e+00 883.00
IUUC-Pca-100777 Procavia capensis 86.16 1.00e-53 204.00
IUUC-Pva-102912 Pteropus vampyrus 91.13 0.00e+00 873.00
IUUC-Rno-104970 Rattus norvegicus 95.64 0.00e+00 818.00
IUUC-Sha-106821 Sarcophilus harrisii 93.15 0.00e+00 787.00
IUUC-Sar-113508 Sorex araneus 95.58 1.00e-101 363.00
IUUC-Ssc-116373 Sus scrofa 92.01 0.00e+00 780.00
IUUC-Tgu-117223 Taeniopygia guttata 90.10 0.00e+00 671.00
IUUC-Tru-118116 Takifugu rubripes 50.45 5.00e-111 394.00
IUUC-Tsy-119525 Tarsius syrichta 96.32 0.00e+00 663.00
IUUC-Tni-119799 Tetraodon nigroviridis 79.27 0.00e+00 702.00
IUUC-Ttr-128611 Tursiops truncatus 87.61 0.00e+00 748.00
IUUC-Vpa-130806 Vicugna pacos 62.01 1.00e-111 396.00
IUUC-Xtr-132913 Xenopus tropicalis 88.36 0.00e+00 758.00
Created Date 25-Jun-2017

https://dev.news.makassarkota.go.id/public/pgsoft-demo/ https://jdih.sumbawabaratkab.go.id/lato/pg-soft-demo/ https://dev.news.makassarkota.go.id/public/slot-gacor/ http://pbb.tanahbumbukab.go.id/-/slot-gacor/ slot gacor https://siakad.unipra.ac.id/sass/slot-gacor-x500/ http://kpm.dinus.ac.id/assets/images/berita/slot/
Copyright © 2004-2017.The CUCKOO Workgroup. All Rights Reserved