iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cfa-020231

Ensembl Protein ID

ENSCAFP00000006762.3

UniProt Accession

F1PLS5; F1PLS5_CANLF

Genbank Protein ID

ENSCAFP00000006762

Protein Name

Non-specific serine/threonine protein kinase

Genbank Nucleotide ID

AAEX03000880

Gene Name

MARK4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000004527.3	ENSCAFT00000007300.3	ENSCAFP00000006762.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UBA	96.36	0.00e+00	1278.00	IUUC-Hsa-045897

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Canis familiaris

Protein Sequence
(Fasta)

SVSQCDMVRV KDSNSGVHGT LGSGRSSDKG PSWSSRSLGA RCRNSIASCP EEQPHVGNYR 60
LLRTIGKGNF AKVKLARHIL TGREVAIKII DKTQLNPSSL QKLFREVRIM KGLNHPNIVK 120

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Nucleotide Sequence
(Fasta)

AGTGTGAGTC AGTGTGATAT GGTGAGGGTG AAGGACAGCA ACTCTGGCGT AAACTTTGCC 60
CAGCTCTGGG CCTCAGTTTC CTTACCTTAA GATGGGGATG ATGACCGGAT CGATTCATCC 120

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Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase

Interpro

IPR028375--KA1/Ssp2_C
IPR001772--KA1_dom
IPR011009--Kinase-like_dom
IPR033624--MARK/par1
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS
IPR015940--UBA

PROSITE

PS50032--KA1
PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS50030--UBA

Pfam

PF02149--KA1
PF00069--Pkinase
PF00627--UBA

SMART

SM00220--S_TKc
SM00165--UBA

Gene Ontology

GO:0005813--C:centrosome
GO:0036064--C:ciliary basal body
GO:0043005--C:neuron projection
GO:0005524--F:ATP binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0050321--F:tau-protein kinase activity
GO:0030010--P:establishment of cell polarity
GO:0001578--P:microtubule bundle formation
GO:0007399--P:nervous system development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Bta-013546	Bos taurus	96.61	0.00e+00	1266.00
IUUC-Cja-019522	Callithrix jacchus	98.12	0.00e+00	1305.00
IUUC-Cpo-022532	Cavia porcellus	96.90	0.00e+00	1255.00
IUUC-Csa-023700	Chlorocebus sabaeus	94.89	0.00e+00	1237.00
IUUC-Dor-030478	Dipodomys ordii	94.29	0.00e+00	1208.00
IUUC-Eca-033684	Equus caballus	94.05	0.00e+00	1057.00
IUUC-Fca-035898	Felis catus	96.47	0.00e+00	1302.00
IUUC-Gmo-039460	Gadus morhua	73.02	0.00e+00	919.00
IUUC-Gac-042324	Gasterosteus aculeatus	68.65	0.00e+00	956.00
IUUC-Ggo-044770	Gorilla gorilla	94.42	0.00e+00	1210.00
IUUC-Hsa-045897	Homo sapiens	97.04	0.00e+00	1294.00
IUUC-Itr-049080	Ictidomys tridecemlineatus	97.71	0.00e+00	1342.00
IUUC-Lch-049752	Latimeria chalumnae	67.52	0.00e+00	938.00
IUUC-Laf-053534	Loxodonta africana	93.88	0.00e+00	1270.00
IUUC-Mcc-054804	Macaca mulatta	97.17	0.00e+00	1274.00
IUUC-Meu-056140	Macropus eugenii	93.66	0.00e+00	1296.00
IUUC-Mmr-060587	Microcebus murinus	96.63	0.00e+00	1305.00
IUUC-Mmu-064289	Mus musculus	96.90	0.00e+00	1320.00
IUUC-Mlu-067933	Myotis lucifugus	84.14	0.00e+00	1026.00
IUUC-Nle-069719	Nomascus leucogenys	91.67	0.00e+00	1033.00
IUUC-Opr-070607	Ochotona princeps	88.68	0.00e+00	1175.00
IUUC-Ont-071444	Oreochromis niloticus	70.12	0.00e+00	981.00
IUUC-Ola-086790	Oryzias latipes	64.07	0.00e+00	910.00
IUUC-Oga-088194	Otolemur garnettii	97.17	0.00e+00	1272.00
IUUC-Oar-089936	Ovis aries	85.75	0.00e+00	1124.00
IUUC-Ptr-091413	Pan troglodytes	97.17	0.00e+00	1274.00
IUUC-Pab-098074	Pongo abelii	95.15	0.00e+00	1228.00
IUUC-Pva-103242	Pteropus vampyrus	97.30	0.00e+00	1251.00
IUUC-Rno-105368	Rattus norvegicus	97.04	0.00e+00	1298.00
IUUC-Tru-117575	Takifugu rubripes	65.54	0.00e+00	895.00
IUUC-Ttr-129093	Tursiops truncatus	95.11	0.00e+00	1224.00
IUUC-Xtr-132367	Xenopus tropicalis	72.14	0.00e+00	837.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence