iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-005132

UUCD1 version

UUC-AnC-00991

Ensembl Protein ID

ENSACAP00000019251.1

UniProt Accession

H9GS67; H9GS67_ANOCA

Protein Name

Uncharacterized protein

Gene Name

USP2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000027046.2	ENSACAT00000022479.2	ENSACAP00000019251.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	5.00e-100	334.9	257	588

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelw.kskkkavsprellkalkkeaeefsgy 87
           tGl+NlgNtC+mNS+LQcLsn++elr+++l+ ++ ++ln+  ++ ++ +l+ +++kl+++lw +s +++vsp+e++++++++a++f gy
   Q: 257  TGLRNLGNTCFMNSILQCLSNTKELRDYCLQnQYVRDLNN--NSRMQMNLMAEFAKLIQALWtSSPNESVSPSEFKTQIQRYAPRFVGY 343
           7******************************555566655..5789****************999999********************* PP
   S: 88   eqqDaqEflaflldqleeelkk....eknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldl 172
           +qqDaqEfl+flld+l++e+++     k  + +++ +  ++e+ ++ + +   +++s i dlF gqlks+++c  c++ s+ ++pf+dl
   Q: 344  NQQDAQEFLRFLLDGLHSEVNRilvrPKGGSSDSLDHLPDEEKGRQMWMRYLAREDSRIGDLFVGQLKSSLTCSVCGHCSTAFDPFWDL 432
           ********************99554422222333333333344444999**************************************** PP
   S: 173  slpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ld 260
           slp+ +k+   + +l dcL+ ftke+ l+g++k  c +ck++++++kk++++++P++L+lhLkRf  se++ +++k+++ v+fpl+ Ld
   Q: 433  SLPIAKKSYG-EVNLADCLRLFTKEDILDGDEKPTCCHCKARTKCTKKFSIQRFPKILVLHLKRF--SEARIRSSKLTTFVNFPLKdLD 518
           ******9976.789***************************************************..9999****************** PP
   S: 261  lspfctspeekqkekkkYeLiavvvHsGslssGHYvayvkn.ekgkWllfdDskVtevkeeevleetgstaYvlfYk 336
           l++f +++++    +  Y+L+av +HsG++ +GHY+ay+kn  +g+W  f+Ds+Vt+++ + v +   s+aY+lfY+
   Q: 519  LREFASQSCN----HAVYNLYAVSNHSGTTMGGHYTAYCKNpVSGEWHAFNDSRVTPLSASHVRS---SDAYLLFYE 588
           *******775....679************************44666*******************...********8 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MSQISSTLKR YVDPPSTYSR ASPSYGTYPY SSNLSSSYTD REKVGYKSTS PSTYLASTHL 60
RTSGSTSSSS SLNYDGGGRY LQRPDSGTRL SPSYLRAPVR PPGSGGLSGG ATGYSFGTGY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCCCAGA TCTCCTCCAC CTTGAAGCGC TACGTCGACC CACCTTCGAC ATACAGCCGG 60
GCCTCCCCCA GTTATGGCAC CTATCCCTAC TCCTCCAACC TCTCCTCCTC GTATACGGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005938--C:cell cortex
GO:0005634--C:nucleus
GO:0048471--C:perinuclear region of cytoplasm
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0032922--P:circadian regulation of gene expression
GO:0043153--P:entrainment of circadian clock by photoperiod
GO:0045475--P:locomotor rhythm
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0045931--P:positive regulation of mitotic cell cycle
GO:0016579--P:protein deubiquitination
GO:0050821--P:protein stabilization
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001988	Ailuropoda melanoleuca	60.97	0.00e+00	675.00
IUUC-Ame-011102	Astyanax mexicanus	74.21	8.00e-147	513.00
IUUC-Bta-012529	Bos taurus	59.84	0.00e+00	646.00
IUUC-Cja-019016	Callithrix jacchus	59.62	1.00e-178	619.00
IUUC-Cfa-020714	Canis familiaris	61.09	0.00e+00	674.00
IUUC-Cpo-021727	Cavia porcellus	61.61	0.00e+00	669.00
IUUC-Csa-023071	Chlorocebus sabaeus	79.66	4.00e-164	570.00
IUUC-Cin-025797	Ciona intestinalis	53.16	1.00e-100	359.00
IUUC-Csv-026132	Ciona savignyi	52.44	8.00e-104	370.00
IUUC-Dre-027872	Danio rerio	79.18	2.00e-162	565.00
IUUC-Dno-029329	Dasypus novemcinctus	62.18	0.00e+00	709.00
IUUC-Dor-030574	Dipodomys ordii	59.75	0.00e+00	649.00
IUUC-Dme-032208	Drosophila melanogaster	49.58	4.00e-88	319.00
IUUC-Ete-032725	Echinops telfairi	47.66	1.00e-83	304.00
IUUC-Eca-033361	Equus caballus	61.00	0.00e+00	664.00
IUUC-Eeu-035272	Erinaceus europaeus	82.61	4.00e-83	302.00
IUUC-Fca-036497	Felis catus	61.32	0.00e+00	675.00
IUUC-Fal-036766	Ficedula albicollis	67.21	0.00e+00	703.00
IUUC-Gmo-039129	Gadus morhua	64.69	1.00e-121	429.00
IUUC-Gga-040889	Gallus gallus	87.06	1.00e-153	536.00
IUUC-Gac-042475	Gasterosteus aculeatus	69.25	4.00e-139	487.00
IUUC-Ggo-044814	Gorilla gorilla	75.14	3.00e-145	507.00
IUUC-Hsa-045937	Homo sapiens	60.42	0.00e+00	650.00
IUUC-Itr-048171	Ictidomys tridecemlineatus	60.70	0.00e+00	677.00
IUUC-Lch-050527	Latimeria chalumnae	57.99	1.00e-178	619.00
IUUC-Loc-052697	Lepisosteus oculatus	75.57	5.00e-160	557.00
IUUC-Laf-054167	Loxodonta africana	59.48	0.00e+00	671.00
IUUC-Mcc-055584	Macaca mulatta	60.29	0.00e+00	655.00
IUUC-Meu-056542	Macropus eugenii	60.90	0.00e+00	663.00
IUUC-Mga-060020	Meleagris gallopavo	65.03	0.00e+00	672.00
IUUC-Mmr-060989	Microcebus murinus	61.13	0.00e+00	668.00
IUUC-Mdo-062761	Monodelphis domestica	61.33	0.00e+00	660.00
IUUC-Mmu-063710	Mus musculus	60.66	0.00e+00	664.00
IUUC-Mpu-066573	Mustela putorius furo	61.77	0.00e+00	677.00
IUUC-Nle-070013	Nomascus leucogenys	59.63	9.00e-177	613.00
IUUC-Opr-070907	Ochotona princeps	59.52	0.00e+00	649.00
IUUC-Ont-071944	Oreochromis niloticus	79.66	9.00e-165	572.00
IUUC-Oan-073105	Ornithorhynchus anatinus	74.69	6.00e-135	473.00
IUUC-Ocu-073941	Oryctolagus cuniculus	60.70	0.00e+00	655.00
IUUC-Ola-086724	Oryzias latipes	69.57	2.00e-146	511.00
IUUC-Oga-088973	Otolemur garnettii	60.65	0.00e+00	660.00
IUUC-Oar-089916	Ovis aries	61.81	0.00e+00	693.00
IUUC-Ptr-090998	Pan troglodytes	60.26	0.00e+00	650.00
IUUC-Pan-092686	Papio anubis	60.45	0.00e+00	657.00
IUUC-Psi-093284	Pelodiscus sinensis	73.70	1.00e-128	452.00
IUUC-Pma-094462	Petromyzon marinus	65.83	5.00e-79	286.00
IUUC-Pno-094986	Phaeosphaeria nodorum	33.75	3.00e-42	167.00
IUUC-Pfo-097352	Poecilia formosa	77.84	2.00e-168	585.00
IUUC-Pab-098688	Pongo abelii	54.03	4.00e-156	544.00
IUUC-Pca-100205	Procavia capensis	77.59	3.00e-162	565.00
IUUC-Pva-103188	Pteropus vampyrus	60.03	0.00e+00	654.00
IUUC-Rno-105853	Rattus norvegicus	61.36	0.00e+00	677.00
IUUC-Sce-106166	Saccharomyces cerevisiae	36.31	1.00e-53	204.00
IUUC-Sha-107237	Sarcophilus harrisii	61.04	0.00e+00	667.00
IUUC-Sar-113103	Sorex araneus	77.01	2.00e-156	545.00
IUUC-Ssc-115955	Sus scrofa	61.35	0.00e+00	652.00
IUUC-Tgu-116894	Taeniopygia guttata	74.84	0.00e+00	659.00
IUUC-Tru-117703	Takifugu rubripes	66.09	1.00e-129	455.00
IUUC-Tsy-118879	Tarsius syrichta	71.30	1.00e-177	615.00
IUUC-Tni-119866	Tetraodon nigroviridis	77.88	2.00e-154	538.00
IUUC-Tbe-127367	Tupaia belangeri	49.66	2.00e-90	326.00
IUUC-Ttr-128773	Tursiops truncatus	59.48	0.00e+00	656.00
IUUC-Vpa-130402	Vicugna pacos	81.98	3.00e-102	365.00
IUUC-Xtr-132658	Xenopus tropicalis	62.01	2.00e-165	575.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence