iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Itr-048171

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTP01052994

Gene Name

USP2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000005428.2	ENSSTOT00000005434.2	ENSSTOP00000004862.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	9.90e-99	330.7	275	604

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelw.kskkkavsprellkalkkeaeefsgye 88
           Gl+NlgNtC+mNS+LQcLsn++elr+++l+  + ++l+++  ++ +++l+++++kl++ +w +s + +vsp+e++++++++a++f gy+
   Q: 275  GLRNLGNTCFMNSILQCLSNTRELRDYCLQrLYMRDLSHT--SNAHTTLMEEFAKLIQTIWtSSPNDVVSPSEFKTQIQRYAPRFVGYN 361
           9*****************************7777888776..6899***************889999********************** PP
   S: 89   qqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.....aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldl 172
           qqDaqEfl+flld+l++e+++ +  pk++ e+ d+  l+d+      ++k  ++++s i dlF gqlks+++c +c+  s+ ++pf+dl
   Q: 362  QQDAQEFLRFLLDGLHNEVNRVTVRPKSNPENLDH--LPDDekgrqMWRKYLEREDSRIGDLFVGQLKSSLTCTDCGYCSTVFDPFWDL 448
           *******************9955555554444443..2222335559****************************************** PP
   S: 173  slpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ld 260
           slp+ ++    + +l dc++ ftke+ l+g++k  c +c++++++ kk++++++P++L+lhLkRf  se++ + +k+++ v+fpl+ Ld
   Q: 449  SLPIAKRGYP-EVTLMDCMRLFTKEDVLDGDEKPTCCRCRARKRCIKKFSIQRFPKILVLHLKRF--SESRIRTSKLTTFVNFPLRdLD 534
           ******9976.779***************************************************..88899***************** PP
   S: 261  lspfctspeekqkekkkYeLiavvvHsGslssGHYvayvkn.ekgkWllfdDskVtevkeeevleetgstaYvlfYk 336
           l++f +++++    +  Y+L+av +HsG++ +GHY+ay+++  +g+W +f+Ds+Vt+++ ++v +   s+aY+lfY+
   Q: 535  LREFASENTN----HAVYNLYAVSNHSGTTMGGHYTAYCRSpVTGEWHTFNDSSVTPMSSSQVRT---SDAYLLFYE 604
           ******9553....78*************************44666*******************...********8 PP

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

MSQLSSTLKR YTESARYTDV PYAKSGYGTY TPSSYGANLA ASFLEKEKLG FKPSPPTGFL 60
PRPRTYGPSS ILDYDRGRPL LRPDIIGGSK RAESQTRGTE RSSGSGLSGG SGFPYGVTSN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGCTTCTGGG CTCTCCACTG CGTTCTCTGC CCTCCCGGGG AGGAAGCCCC CAGGTCCCAT 60
CCAGTGCCCC TGGACACAGG TCAGTAGCGG CCCCTTTGGT GTCTGAGCTT TGCCTGGGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005938--C:cell cortex
GO:0005634--C:nucleus
GO:0048471--C:perinuclear region of cytoplasm
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0032922--P:circadian regulation of gene expression
GO:0043153--P:entrainment of circadian clock by photoperiod
GO:0045475--P:locomotor rhythm
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0045931--P:positive regulation of mitotic cell cycle
GO:0016579--P:protein deubiquitination
GO:0050821--P:protein stabilization
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001988	Ailuropoda melanoleuca	94.44	0.00e+00	1099.00
IUUC-Aca-005132	Anolis carolinensis	59.78	0.00e+00	687.00
IUUC-Ame-011102	Astyanax mexicanus	74.43	2.00e-145	508.00
IUUC-Bta-012529	Bos taurus	91.01	0.00e+00	1016.00
IUUC-Bra-016678	Brassica rapa	35.86	3.00e-47	182.00
IUUC-Cja-019016	Callithrix jacchus	89.12	0.00e+00	1028.00
IUUC-Cfa-020714	Canis familiaris	93.79	0.00e+00	1117.00
IUUC-Cpo-021727	Cavia porcellus	90.03	0.00e+00	1040.00
IUUC-Csa-023071	Chlorocebus sabaeus	97.71	0.00e+00	686.00
IUUC-Cin-025797	Ciona intestinalis	50.43	2.00e-95	341.00
IUUC-Csv-026132	Ciona savignyi	51.48	9.00e-98	350.00
IUUC-Dre-027872	Danio rerio	80.64	2.00e-163	568.00
IUUC-Dno-029329	Dasypus novemcinctus	91.67	0.00e+00	1064.00
IUUC-Dor-030574	Dipodomys ordii	92.81	0.00e+00	1064.00
IUUC-Dme-032208	Drosophila melanogaster	47.63	8.00e-83	301.00
IUUC-Ete-032725	Echinops telfairi	82.34	4.00e-176	610.00
IUUC-Eca-033361	Equus caballus	94.61	0.00e+00	1103.00
IUUC-Eeu-035272	Erinaceus europaeus	78.00	0.00e+00	703.00
IUUC-Fca-036497	Felis catus	94.77	0.00e+00	1108.00
IUUC-Fal-036766	Ficedula albicollis	63.33	0.00e+00	685.00
IUUC-Gmo-039129	Gadus morhua	66.77	3.00e-123	434.00
IUUC-Gga-040889	Gallus gallus	84.05	2.00e-147	515.00
IUUC-Gac-042475	Gasterosteus aculeatus	69.83	8.00e-137	479.00
IUUC-Ggo-044814	Gorilla gorilla	92.53	7.00e-178	615.00
IUUC-Hsa-045937	Homo sapiens	90.85	0.00e+00	1031.00
IUUC-Lch-050527	Latimeria chalumnae	60.70	0.00e+00	634.00
IUUC-Loc-052697	Lepisosteus oculatus	79.14	1.00e-161	563.00
IUUC-Laf-054167	Loxodonta africana	86.50	0.00e+00	1011.00
IUUC-Mcc-055584	Macaca mulatta	91.83	0.00e+00	1067.00
IUUC-Meu-056542	Macropus eugenii	85.97	0.00e+00	956.00
IUUC-Mga-060020	Meleagris gallopavo	60.36	0.00e+00	646.00
IUUC-Mmr-060989	Microcebus murinus	93.30	0.00e+00	1085.00
IUUC-Mdo-062761	Monodelphis domestica	85.32	0.00e+00	954.00
IUUC-Mmu-063710	Mus musculus	92.57	0.00e+00	1087.00
IUUC-Mpu-066573	Mustela putorius furo	94.28	0.00e+00	1104.00
IUUC-Nle-070013	Nomascus leucogenys	90.74	0.00e+00	997.00
IUUC-Opr-070907	Ochotona princeps	91.03	0.00e+00	1024.00
IUUC-Ont-071944	Oreochromis niloticus	81.84	1.00e-164	571.00
IUUC-Oan-073105	Ornithorhynchus anatinus	79.35	2.00e-148	518.00
IUUC-Ocu-073941	Oryctolagus cuniculus	92.50	0.00e+00	1068.00
IUUC-Ola-087412	Oryzias latipes	69.81	9.00e-154	536.00
IUUC-Oga-088973	Otolemur garnettii	92.81	0.00e+00	1081.00
IUUC-Oar-089916	Ovis aries	91.67	0.00e+00	1066.00
IUUC-Ptr-090998	Pan troglodytes	91.18	0.00e+00	1039.00
IUUC-Pan-092686	Papio anubis	91.99	0.00e+00	1070.00
IUUC-Psi-093284	Pelodiscus sinensis	71.38	4.00e-124	437.00
IUUC-Pma-094462	Petromyzon marinus	62.50	2.00e-73	268.00
IUUC-Pno-094986	Phaeosphaeria nodorum	32.11	1.00e-39	158.00
IUUC-Pfo-097352	Poecilia formosa	79.21	5.00e-168	584.00
IUUC-Pab-098688	Pongo abelii	84.97	0.00e+00	929.00
IUUC-Pca-100205	Procavia capensis	93.95	0.00e+00	645.00
IUUC-Pva-103188	Pteropus vampyrus	93.63	0.00e+00	1061.00
IUUC-Rno-105853	Rattus norvegicus	93.37	0.00e+00	1125.00
IUUC-Sha-107237	Sarcophilus harrisii	85.32	0.00e+00	950.00
IUUC-Sar-113103	Sorex araneus	91.64	0.00e+00	629.00
IUUC-Ssc-115955	Sus scrofa	93.46	0.00e+00	1081.00
IUUC-Tgu-116894	Taeniopygia guttata	69.81	0.00e+00	632.00
IUUC-Tru-117703	Takifugu rubripes	66.09	1.00e-134	472.00
IUUC-Tsy-118879	Tarsius syrichta	94.62	0.00e+00	820.00
IUUC-Tni-119866	Tetraodon nigroviridis	74.56	2.00e-154	538.00
IUUC-Tbe-127367	Tupaia belangeri	83.49	0.00e+00	666.00
IUUC-Ttr-128773	Tursiops truncatus	90.03	0.00e+00	1065.00
IUUC-Vpa-130402	Vicugna pacos	82.69	0.00e+00	798.00
IUUC-Xtr-132658	Xenopus tropicalis	56.96	0.00e+00	627.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence