iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000016056.2	ENSLACT00000026534.1	ENSLACP00000022381.1
ENSLACG00000016056.2	ENSLACT00000018360.1	ENSLACP00000018228.1
ENSLACG00000016056.2	ENSLACT00000018361.1	ENSLACP00000018229.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	4.00e-101	338.8	265	594

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelw.kskkkavsprellkalkkeaeefsgy 87
           +Gl+NlgNtC+mNS+LQcLsn ++lr+++l+ ++k++ln    + ++++l+++++kl++ +w +s++++vsp+e++++++k+a++f gy
   Q: 265  VGLRNLGNTCFMNSILQCLSNSRDLRDYCLQnSYKRDLNS---SRTNTALMEEFAKLIQTIWtSSSNEVVSPSEFKTQIQKYAPRFVGY 350
           6******************************566666665...5799***************99999********************** PP
   S: 88   eqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.....aeekkkkknkslisdlFqgqlksqikclecdnvssreepfld 171
           +qqDaqEfl+flld+l++e+++ +  pk   e+ d  +l+de      ++k  ++++s i+dlF gqlks+++c ec+  s+ ++pf+d
   Q: 351  NQQDAQEFLRFLLDGLHNEVNHVTVRPKAVVEDFD--HLPDEekgkrMWKKYLEREDSKIVDLFVGQLKSSLTCSECGYCSTVFDPFWD 437
           ********************885555544444444..33333335559***************************************** PP
   S: 172  lslpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.L 259
           lslp+ +k    ++sl dc++ ftke+ l+g++k  c +ck +++++kk++++k+P++L+lhLkRf  se++ + +k++  v+fpl+ L
   Q: 438  LSLPIAKKGYG-ETSLMDCMRLFTKEDVLDGDEKPTCYRCKVRRKCTKKFTIQKFPRILVLHLKRF--SEARIRTSKLTAFVNFPLRdL 523
           ******99965.88****************************************************..9999***************** PP
   S: 260  dlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvkn.ekgkWllfdDskVtevkeeevleetgstaYvlfYk 336
           dl++f +++++    ++ Y+L+av +HsG++ +GHY+ay+k+  +g+W++f+Ds+Vt+++ ++v +   s+aYvlfY+
   Q: 524  DLREFASDNST----HVVYNLYAVSNHSGTTLGGHYTAYCKHpLSGEWYTFNDSRVTPMSSNQVRT---SDAYVLFYE 594
           ******99554....78*************************55677*******************...********8 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

MLAFSLPLRH TRDMSRSSAM KQYITPTYTS PHYSSYATNL SSSYAANLSS SYVDKDKLTS 60
KSGLPASYLN HSRARNCNVS SEPDRGRQVL RSEALGRRSE SLSRAPVKNY RSGLSGGYST 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATTACTGCAG TTGTTTCTGC TTCAGAGGTC TGTAATTGGT TTACAAAGCA ATACAATGTA 60
ATTGCACTTT CACTGAAAGG TTTTAAAAGA TCAGGTTAGG TTTGCTCATC GGAATAAACT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

lcm:102360785

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001988	Ailuropoda melanoleuca	62.25	0.00e+00	665.00
IUUC-Aca-005132	Anolis carolinensis	58.59	0.00e+00	650.00
IUUC-Ame-011102	Astyanax mexicanus	80.70	8.00e-159	552.00
IUUC-Bta-012529	Bos taurus	62.35	5.00e-179	620.00
IUUC-Cja-019016	Callithrix jacchus	58.39	1.00e-169	589.00
IUUC-Cfa-020714	Canis familiaris	61.59	0.00e+00	662.00
IUUC-Cpo-021727	Cavia porcellus	58.44	0.00e+00	629.00
IUUC-Csa-023071	Chlorocebus sabaeus	82.75	2.00e-168	584.00
IUUC-Cin-025797	Ciona intestinalis	52.02	7.00e-102	363.00
IUUC-Csv-026132	Ciona savignyi	50.00	2.00e-99	356.00
IUUC-Dre-027872	Danio rerio	86.83	8.00e-176	609.00
IUUC-Dno-029329	Dasypus novemcinctus	59.54	0.00e+00	671.00
IUUC-Dor-030574	Dipodomys ordii	61.47	0.00e+00	640.00
IUUC-Dme-032208	Drosophila melanogaster	49.11	1.00e-84	308.00
IUUC-Ete-032725	Echinops telfairi	48.27	3.00e-77	282.00
IUUC-Eca-033361	Equus caballus	60.76	0.00e+00	651.00
IUUC-Eeu-035272	Erinaceus europaeus	83.06	4.00e-87	315.00
IUUC-Fca-036497	Felis catus	61.09	0.00e+00	659.00
IUUC-Fal-036766	Ficedula albicollis	59.72	5.00e-170	590.00
IUUC-Gmo-039129	Gadus morhua	69.75	3.00e-133	468.00
IUUC-Gga-040889	Gallus gallus	80.13	5.00e-142	497.00
IUUC-Gac-042475	Gasterosteus aculeatus	72.51	4.00e-148	517.00
IUUC-Ggo-044814	Gorilla gorilla	77.26	4.00e-148	517.00
IUUC-Hsa-045937	Homo sapiens	59.77	4.00e-180	624.00
IUUC-Itr-048171	Ictidomys tridecemlineatus	60.49	0.00e+00	654.00
IUUC-Loc-052697	Lepisosteus oculatus	83.48	2.00e-175	608.00
IUUC-Laf-054167	Loxodonta africana	58.91	0.00e+00	660.00
IUUC-Mcc-055584	Macaca mulatta	60.43	0.00e+00	640.00
IUUC-Meu-056542	Macropus eugenii	64.12	0.00e+00	650.00
IUUC-Mga-060020	Meleagris gallopavo	57.45	2.00e-169	588.00
IUUC-Mmr-060989	Microcebus murinus	59.37	0.00e+00	645.00
IUUC-Mdo-062761	Monodelphis domestica	63.07	0.00e+00	643.00
IUUC-Mmu-063710	Mus musculus	59.61	0.00e+00	653.00
IUUC-Mpu-066573	Mustela putorius furo	61.02	0.00e+00	659.00
IUUC-Mlu-067359	Myotis lucifugus	47.47	1.00e-82	300.00
IUUC-Nle-070013	Nomascus leucogenys	59.38	8.00e-172	596.00
IUUC-Opr-070907	Ochotona princeps	61.26	0.00e+00	628.00
IUUC-Ont-071944	Oreochromis niloticus	87.43	2.00e-179	620.00
IUUC-Oan-073105	Ornithorhynchus anatinus	73.72	9.00e-134	469.00
IUUC-Ocu-073941	Oryctolagus cuniculus	60.83	0.00e+00	640.00
IUUC-Ola-087412	Oryzias latipes	69.16	3.00e-165	575.00
IUUC-Oga-088973	Otolemur garnettii	59.60	0.00e+00	644.00
IUUC-Oar-089916	Ovis aries	60.43	0.00e+00	662.00
IUUC-Ptr-090998	Pan troglodytes	60.10	0.00e+00	629.00
IUUC-Pan-092686	Papio anubis	60.43	0.00e+00	640.00
IUUC-Psi-093284	Pelodiscus sinensis	66.56	6.00e-113	400.00
IUUC-Pma-094462	Petromyzon marinus	71.58	4.00e-79	286.00
IUUC-Pno-094986	Phaeosphaeria nodorum	33.13	8.00e-43	169.00
IUUC-Pfo-097352	Poecilia formosa	86.26	0.00e+00	635.00
IUUC-Pab-098688	Pongo abelii	54.80	1.00e-154	539.00
IUUC-Pca-100205	Procavia capensis	79.24	8.00e-164	570.00
IUUC-Pva-103188	Pteropus vampyrus	59.93	0.00e+00	637.00
IUUC-Pte-104348	Pyrenophora teres	32.24	4.00e-42	166.00
IUUC-Rno-105853	Rattus norvegicus	60.71	0.00e+00	664.00
IUUC-Sha-107237	Sarcophilus harrisii	63.96	0.00e+00	663.00
IUUC-Smo-108942	Selaginella moellendorffii	38.55	3.00e-48	185.00
IUUC-Sar-113103	Sorex araneus	77.78	3.00e-156	543.00
IUUC-Ssc-115955	Sus scrofa	60.93	0.00e+00	631.00
IUUC-Tgu-116894	Taeniopygia guttata	66.74	2.00e-169	588.00
IUUC-Tru-117703	Takifugu rubripes	68.53	1.00e-135	476.00
IUUC-Tsy-118879	Tarsius syrichta	70.39	3.00e-173	601.00
IUUC-Tni-119866	Tetraodon nigroviridis	84.39	3.00e-167	580.00
IUUC-Tbe-127367	Tupaia belangeri	46.92	2.00e-81	296.00
IUUC-Ttr-128773	Tursiops truncatus	58.87	0.00e+00	627.00
IUUC-Vpa-130402	Vicugna pacos	83.04	7.00e-109	387.00
IUUC-Xtr-132658	Xenopus tropicalis	64.89	9.00e-172	596.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence