iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062761

UUCD1 version

UUC-MoD-01119

Ensembl Protein ID

ENSMODP00000016533.2

UniProt Accession

F7EVY9; F7EVY9_MONDO

Protein Name

Uncharacterized protein

Gene Name

USP2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000013213.2	ENSMODT00000016837.2	ENSMODP00000016533.2
ENSMODG00000013213.2	ENSMODT00000016838.2	ENSMODP00000016534.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	3.30e-99	332.4	263	592

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelw.kskkkavsprellkalkkeaeefsgye 88
           Gl+NlgNtC+mNS+LQcLsn++elr+++l+  + ++ln +  ++ +++l+++++kl++ +w +s + +vsp+e++++++++a++f gy+
   Q: 263  GLRNLGNTCFMNSILQCLSNTRELRDYCLQrLYLRDLNSS--SHAHTALMEEFAKLIQTIWtSSANDVVSPSEFKTQIQRFAPRFVGYN 349
           9*****************************7788888877..6899***************999999********************** PP
   S: 89   qqDaqEflaflldqleeelkk...eknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlsl 174
           qqDaqEfl+flld+l++e+++   + +++ e++ +  ++e+ ++ ++k  ++++s i dlF gqlks+++c ec+  s+ ++pf+dlsl
   Q: 350  QQDAQEFLRFLLDGLHNEVNRvtvRPKSNPENLDHLPDEEKGRQMWRKYLEREDSRIGDLFVGQLKSSLTCTECGYCSTVFDPFWDLSL 438
           *******************99444333333333333444455559******************************************** PP
   S: 175  pvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ldls 262
           p+ ++    + +l dc++ ftke+ l+g++k  c +c++++++ kk++++k+P++L+lhLkRf  se++ + +k+++ v+fpl+ Ldl+
   Q: 439  PIAKRGYP-EVTLMDCMRLFTKEDVLDGDEKPTCCRCRARKRCIKKFSIQKFPKILVLHLKRF--SESRIRTSKLTTFVNFPLRdLDLR 524
           ****9976.779***************************************************..88899******************* PP
   S: 263  pfctspeekqkekkkYeLiavvvHsGslssGHYvayvkn.ekgkWllfdDskVtevkeeevleetgstaYvlfYk 336
           +f +++++    +  Y+L+av +HsG++ +GHY+ay+++  +g+W +f+Ds+Vt+++ ++v +   s+aY+lfY+
   Q: 525  EFASENTN----HAVYNLYAVSNHSGTTMGGHYTAYCRSpVTGEWHTFNDSSVTPMSSSQVRS---SDAYLLFYE 592
           ****9553....78*************************44666*******************...********8 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MSQLSSTLKR YTDSSRYTDT PYSKSSYGSY TPSSYGTNLA ASFLEKEKLN FKPAHSSGFL 60
NTRPRTYGPA SILDYDRGRP VLRPEVGGII KRGESQSRIT ERPSGSGLSG GSNLPYGMPS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCCCAGC TCTCCTCCAC CCTGAAGCGC TACACAGATT CATCCCGCTA CACAGACACC 60
CCTTACTCAA AATCCAGCTA TGGGTCCTAC ACCCCTTCCT CCTATGGAAC CAACTTGGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005938--C:cell cortex
GO:0005634--C:nucleus
GO:0048471--C:perinuclear region of cytoplasm
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0032922--P:circadian regulation of gene expression
GO:0043153--P:entrainment of circadian clock by photoperiod
GO:0045475--P:locomotor rhythm
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0045931--P:positive regulation of mitotic cell cycle
GO:0016579--P:protein deubiquitination
GO:0050821--P:protein stabilization
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

mdo:100024409

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001988	Ailuropoda melanoleuca	85.83	0.00e+00	994.00
IUUC-Aca-005132	Anolis carolinensis	61.07	0.00e+00	686.00
IUUC-Ame-011102	Astyanax mexicanus	75.72	1.00e-144	506.00
IUUC-Bta-012529	Bos taurus	86.49	0.00e+00	944.00
IUUC-Bra-016678	Brassica rapa	37.39	2.00e-49	189.00
IUUC-Cja-019016	Callithrix jacchus	83.14	0.00e+00	938.00
IUUC-Cfa-020714	Canis familiaris	86.49	0.00e+00	1015.00
IUUC-Cpo-021727	Cavia porcellus	83.53	0.00e+00	949.00
IUUC-Csa-023071	Chlorocebus sabaeus	95.95	0.00e+00	667.00
IUUC-Cin-025797	Ciona intestinalis	50.87	2.00e-95	342.00
IUUC-Csv-026132	Ciona savignyi	50.58	4.00e-98	352.00
IUUC-Dre-027872	Danio rerio	82.65	4.00e-164	570.00
IUUC-Dno-029329	Dasypus novemcinctus	84.68	0.00e+00	983.00
IUUC-Dor-030574	Dipodomys ordii	85.50	0.00e+00	959.00
IUUC-Dme-032208	Drosophila melanogaster	47.34	2.00e-82	300.00
IUUC-Ete-032725	Echinops telfairi	75.97	3.00e-158	551.00
IUUC-Eca-033361	Equus caballus	86.33	0.00e+00	1001.00
IUUC-Eeu-035272	Erinaceus europaeus	95.08	3.00e-95	342.00
IUUC-Fca-036497	Felis catus	86.16	0.00e+00	1003.00
IUUC-Fal-036766	Ficedula albicollis	65.03	0.00e+00	697.00
IUUC-Gmo-039129	Gadus morhua	66.77	5.00e-123	434.00
IUUC-Gga-040889	Gallus gallus	84.72	6.00e-148	517.00
IUUC-Gac-042475	Gasterosteus aculeatus	70.98	4.00e-138	484.00
IUUC-Ggo-044814	Gorilla gorilla	89.14	3.00e-172	597.00
IUUC-Hsa-045937	Homo sapiens	84.02	0.00e+00	954.00
IUUC-Itr-048171	Ictidomys tridecemlineatus	85.48	0.00e+00	1005.00
IUUC-Lch-050527	Latimeria chalumnae	62.43	0.00e+00	637.00
IUUC-Loc-052697	Lepisosteus oculatus	77.62	1.00e-160	560.00
IUUC-Laf-054167	Loxodonta africana	80.49	0.00e+00	935.00
IUUC-Mcc-055584	Macaca mulatta	85.34	0.00e+00	985.00
IUUC-Meu-056542	Macropus eugenii	96.67	0.00e+00	1062.00
IUUC-Mga-060020	Meleagris gallopavo	61.70	0.00e+00	653.00
IUUC-Mmr-060989	Microcebus murinus	86.00	0.00e+00	994.00
IUUC-Mmu-063710	Mus musculus	82.74	0.00e+00	970.00
IUUC-Mpu-066573	Mustela putorius furo	86.33	0.00e+00	1003.00
IUUC-Nle-070013	Nomascus leucogenys	83.91	0.00e+00	923.00
IUUC-Opr-070907	Ochotona princeps	84.87	0.00e+00	933.00
IUUC-Ont-071944	Oreochromis niloticus	82.66	3.00e-165	574.00
IUUC-Oan-073105	Ornithorhynchus anatinus	79.65	6.00e-148	516.00
IUUC-Ocu-073941	Oryctolagus cuniculus	84.38	0.00e+00	969.00
IUUC-Ola-087412	Oryzias latipes	70.32	2.00e-154	539.00
IUUC-Oga-088973	Otolemur garnettii	85.01	0.00e+00	985.00
IUUC-Oar-089916	Ovis aries	86.82	0.00e+00	995.00
IUUC-Ptr-090998	Pan troglodytes	84.35	0.00e+00	962.00
IUUC-Pan-092686	Papio anubis	85.34	0.00e+00	986.00
IUUC-Psi-093284	Pelodiscus sinensis	70.62	4.00e-123	434.00
IUUC-Pma-094462	Petromyzon marinus	63.16	5.00e-74	270.00
IUUC-Pno-094986	Phaeosphaeria nodorum	31.80	6.00e-40	159.00
IUUC-Pfo-097352	Poecilia formosa	79.78	4.00e-169	588.00
IUUC-Pab-098688	Pongo abelii	77.92	0.00e+00	852.00
IUUC-Pca-100205	Procavia capensis	91.62	0.00e+00	627.00
IUUC-Pva-103188	Pteropus vampyrus	84.35	0.00e+00	968.00
IUUC-Rno-105853	Rattus norvegicus	84.33	0.00e+00	996.00
IUUC-Sha-107237	Sarcophilus harrisii	96.00	0.00e+00	1069.00
IUUC-Sar-113103	Sorex araneus	89.60	2.00e-177	614.00
IUUC-Ssc-115955	Sus scrofa	86.82	0.00e+00	991.00
IUUC-Tgu-116894	Taeniopygia guttata	71.34	0.00e+00	636.00
IUUC-Tru-117703	Takifugu rubripes	65.79	6.00e-133	467.00
IUUC-Tsy-118879	Tarsius syrichta	89.91	0.00e+00	782.00
IUUC-Tni-119866	Tetraodon nigroviridis	79.18	7.00e-154	536.00
IUUC-Tbe-127367	Tupaia belangeri	75.29	2.00e-169	588.00
IUUC-Ttr-128773	Tursiops truncatus	84.82	0.00e+00	985.00
IUUC-Vpa-130402	Vicugna pacos	76.95	0.00e+00	738.00
IUUC-Xtr-132658	Xenopus tropicalis	58.36	5.00e-180	624.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence