iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSNLEG00000007396.1	ENSNLET00000009445.1	ENSNLEP00000009020.1
ENSNLEG00000007396.1	ENSNLET00000009446.1	ENSNLEP00000009021.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.30e-90	303.1	268	576

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelw.kskkkavsprellkalkkeaeefsgye 88
           Gl+NlgNtC+mNS+LQcLsn++elr+++l+  + ++l++   ++ +++l+++++kl++ +w +s + +vsp+e++++++++a++f gy+
   Q: 268  GLRNLGNTCFMNSILQCLSNTRELRDYCLQrLYMRDLHHG--SNAHTALMEEFAKLIQTIWtSSPNDVVSPSEFKTQIQRYAPRFVGYN 354
           9*****************************7778888776..67999**************889999********************** PP
   S: 89   qqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.....aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldl 172
           qqDaqEfl+flld+l++e+++ +  pk++ e+ d+  l+d+      ++k  ++++s i dlF gqlks+++c +c+  s+ ++pf+dl
   Q: 355  QQDAQEFLRFLLDGLHNEVNRVTLRPKSNPENLDH--LPDDekgrqMWRKYLEREDSRIGDLFVGQLKSSLTCTDCGYCSTVFDPFWDL 441
           *******************9944444444444442..2222335559****************************************** PP
   S: 173  slpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ld 260
           slp+ ++    + +l dc++ ftke+ l+g++k  c +c++++++ kk++++++P++L+lhLkRf  se++ + +k+++ v+fpl+ Ld
   Q: 442  SLPIAKRGYP-EVTLMDCMRLFTKEDVLDGDEKPTCCRCRGRKRCIKKFSIQRFPKILVLHLKRF--SESRIRTSKLTTFVNFPLRdLD 527
           ******9976.779***************************************************..88899***************** PP
   S: 261  lspfctspeekqkekkkYeLiavvvHsGslssGHYvayvkn.ekgkWllfdDs 312
           l++f +++++    +  Y+L+av +HsG++ +GHY+ay+++  +g+W +f+Ds
   Q: 528  LREFASENTN----HAVYNLYAVSNHSGTTMGGHYTAYCRSpGTGEWHTFNDS 576
           ******9553....78*************************44555******8 PP

Organism

Nomascus leucogenys

Protein Sequence
(Fasta)

MSQLSSTLKR YTESARYTDA HYAKSGYGAY TPSSYGANLA ASLLEKEKLG FKSVPTSSFF 60
TRPRTYGPSS LLDYDRGRPL LRPDITGGGK RAESQTRVTE RPSGSGLSGG SGFPYGVTNN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCAGACATG AGCCGAGGTC GGGGAGCCCT CTGCGTCAGC CGGTGCTCAC TGCGCCGCGC 60
CAGCGCCAGC GCTAGCCGGG ACTCACCCGC AGCTCCATGC TTGTGCCCGG TTCGACTCGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0045931--P:positive regulation of mitotic cell cycle
GO:0016579--P:protein deubiquitination
GO:0050821--P:protein stabilization
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001988	Ailuropoda melanoleuca	92.37	0.00e+00	1011.00
IUUC-Aca-005132	Anolis carolinensis	59.56	0.00e+00	628.00
IUUC-Ame-011102	Astyanax mexicanus	74.76	3.00e-140	491.00
IUUC-Bta-012529	Bos taurus	89.24	0.00e+00	964.00
IUUC-Cja-019016	Callithrix jacchus	92.77	0.00e+00	1015.00
IUUC-Cfa-020714	Canis familiaris	92.37	0.00e+00	1036.00
IUUC-Cpo-021727	Cavia porcellus	87.52	0.00e+00	943.00
IUUC-Csa-023071	Chlorocebus sabaeus	99.69	0.00e+00	636.00
IUUC-Cin-025797	Ciona intestinalis	51.26	6.00e-88	317.00
IUUC-Csv-026132	Ciona savignyi	51.57	2.00e-91	329.00
IUUC-Dre-027872	Danio rerio	81.50	2.00e-152	531.00
IUUC-Dno-029329	Dasypus novemcinctus	90.12	0.00e+00	983.00
IUUC-Dor-030574	Dipodomys ordii	90.99	0.00e+00	980.00
IUUC-Dme-032208	Drosophila melanogaster	46.71	8.00e-78	285.00
IUUC-Ete-032725	Echinops telfairi	79.66	2.00e-167	582.00
IUUC-Eca-033361	Equus caballus	93.41	0.00e+00	1023.00
IUUC-Eeu-035272	Erinaceus europaeus	77.53	0.00e+00	686.00
IUUC-Fca-036497	Felis catus	93.24	0.00e+00	1023.00
IUUC-Fal-036766	Ficedula albicollis	62.44	0.00e+00	635.00
IUUC-Gmo-039129	Gadus morhua	61.39	5.00e-123	434.00
IUUC-Gga-040889	Gallus gallus	79.01	6.00e-147	514.00
IUUC-Gac-042475	Gasterosteus aculeatus	69.16	1.00e-130	459.00
IUUC-Ggo-044814	Gorilla gorilla	94.04	2.00e-164	571.00
IUUC-Hsa-045937	Homo sapiens	97.57	0.00e+00	1045.00
IUUC-Itr-048171	Ictidomys tridecemlineatus	90.74	0.00e+00	1019.00
IUUC-Lch-050527	Latimeria chalumnae	59.14	6.00e-165	573.00
IUUC-Loc-052697	Lepisosteus oculatus	78.88	2.00e-150	525.00
IUUC-Laf-054167	Loxodonta africana	85.32	0.00e+00	940.00
IUUC-Mcc-055584	Macaca mulatta	97.05	0.00e+00	1075.00
IUUC-Meu-056542	Macropus eugenii	84.08	0.00e+00	876.00
IUUC-Mga-060020	Meleagris gallopavo	58.42	7.00e-171	593.00
IUUC-Mmr-060989	Microcebus murinus	93.93	0.00e+00	1029.00
IUUC-Mdo-062761	Monodelphis domestica	84.43	0.00e+00	882.00
IUUC-Mmu-063710	Mus musculus	87.97	0.00e+00	965.00
IUUC-Mpu-066573	Mustela putorius furo	92.89	0.00e+00	1019.00
IUUC-Opr-070907	Ochotona princeps	89.45	0.00e+00	945.00
IUUC-Ont-071944	Oreochromis niloticus	81.82	9.00e-153	532.00
IUUC-Oan-073105	Ornithorhynchus anatinus	78.47	4.00e-147	513.00
IUUC-Ocu-073941	Oryctolagus cuniculus	91.18	0.00e+00	992.00
IUUC-Ola-087412	Oryzias latipes	74.42	2.00e-142	499.00
IUUC-Oga-088973	Otolemur garnettii	93.59	0.00e+00	1030.00
IUUC-Oar-089916	Ovis aries	89.93	0.00e+00	1012.00
IUUC-Ptr-090998	Pan troglodytes	97.74	0.00e+00	1048.00
IUUC-Pan-092686	Papio anubis	97.22	0.00e+00	1077.00
IUUC-Psi-093284	Pelodiscus sinensis	70.85	2.00e-123	434.00
IUUC-Pma-094462	Petromyzon marinus	65.24	1.00e-74	271.00
IUUC-Pfo-097352	Poecilia formosa	78.96	8.00e-157	546.00
IUUC-Pab-098688	Pongo abelii	97.76	0.00e+00	958.00
IUUC-Pca-100205	Procavia capensis	92.45	1.00e-167	583.00
IUUC-Pva-103188	Pteropus vampyrus	92.37	0.00e+00	980.00
IUUC-Rno-105853	Rattus norvegicus	89.30	0.00e+00	1013.00
IUUC-Sha-107237	Sarcophilus harrisii	83.91	0.00e+00	873.00
IUUC-Sar-113103	Sorex araneus	90.57	3.00e-164	570.00
IUUC-Ssc-115955	Sus scrofa	91.67	0.00e+00	1025.00
IUUC-Tgu-116894	Taeniopygia guttata	68.93	1.00e-165	575.00
IUUC-Tru-117703	Takifugu rubripes	66.77	8.00e-125	439.00
IUUC-Tsy-118879	Tarsius syrichta	96.40	0.00e+00	785.00
IUUC-Tni-119866	Tetraodon nigroviridis	78.37	1.00e-153	535.00
IUUC-Tbe-127367	Tupaia belangeri	83.02	0.00e+00	642.00
IUUC-Ttr-128773	Tursiops truncatus	88.73	0.00e+00	983.00
IUUC-Vpa-130402	Vicugna pacos	82.50	0.00e+00	784.00
IUUC-Xtr-132658	Xenopus tropicalis	55.76	4.00e-166	578.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence