iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ocu-073941

UUCD1 version

UUC-OrC-01022

Ensembl Protein ID

ENSOCUP00000006702.2

UniProt Accession

G1STQ2; G1STQ2_RABIT

Protein Name

Uncharacterized protein

Gene Name

USP2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000007759.3	ENSOCUT00000007758.3	ENSOCUP00000006702.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	5.60e-99	331.5	270	599

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelw.kskkkavsprellkalkkeaeefsgye 88
           Gl+NlgNtC+mNS+LQcLsn++elr+++l+  + ++l+++  ++ +++l+++++kl++ +w +s + +vsp+e++++++++a++f gy+
   Q: 270  GLRNLGNTCFMNSILQCLSNTRELRDYCLQrLYMRDLSHS--SNAHTALMEEFAKLIQTIWtSSPNDVVSPSEFKTQIQRYAPRFVGYN 356
           9*****************************7788888877..6899***************889999********************** PP
   S: 89   qqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.....aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldl 172
           qqDaqEfl+flld+l++e+++ +  pk++ e+ d+  l+d+      ++k  ++++s i dlF gqlks+++c +c+  s+ ++pf+dl
   Q: 357  QQDAQEFLRFLLDGLHNEVNRVTARPKSNPENLDH--LPDDekgrqMWRKYLEREDSRIGDLFVGQLKSSLTCTDCGYCSTVFDPFWDL 443
           *******************9955555555555553..3333346669****************************************** PP
   S: 173  slpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ld 260
           slp+ ++    + +l dc++ ftke+ l+ge+k  c +c++++++ kk++++++P++L+lhLkRf  se++ + +k+++ v+fpl+ Ld
   Q: 444  SLPIAKRGYP-EVTLMDCMRLFTKEDVLDGEEKPTCCRCRARKRCIKKFSIQRFPKILVLHLKRF--SESRIRTSKLTTFVNFPLRdLD 529
           ******9976.779***************************************************..88899***************** PP
   S: 261  lspfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevleetgstaYvlfYk 336
           l++f +++++    +  Y+L+av +HsG++ +GHY+ay+++   + W +f+Ds+Vt+++ ++v +   s+aY+lfY+
   Q: 530  LREFASENTN----HAVYNLYAVSNHSGTTMGGHYTAYCRSPATGeWHTFNDSSVTAMSSSQVRT---SDAYLLFYE 599
           ******9553....78*************************65555*******************...********8 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MSQLSSTLKR YTESTRYTDA PYGKPGYGTY TPSSYGANLA TSFLEKEKLG FKPSPSTSFL 60
TRPGIYGPSS ILDFDRGRPL LRPDIIRGSK RAESQTRGTE RPLGSGLSGG SGCSYGVTSS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCATGAGGC TCCCAGTCCC CACTGAGCGC CGCCCTGAAG GATGTCCCAG CTCTCCTCCA 60
CCCTGAAGCG CTACACAGAA TCGACCCGCT ACACAGATGC CCCTTACGGC AAACCGGGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005938--C:cell cortex
GO:0005634--C:nucleus
GO:0048471--C:perinuclear region of cytoplasm
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0032922--P:circadian regulation of gene expression
GO:0043153--P:entrainment of circadian clock by photoperiod
GO:0045475--P:locomotor rhythm
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0045931--P:positive regulation of mitotic cell cycle
GO:0016579--P:protein deubiquitination
GO:0050821--P:protein stabilization
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

ocu:100339033

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001988	Ailuropoda melanoleuca	93.90	0.00e+00	1074.00
IUUC-Aca-005132	Anolis carolinensis	60.06	0.00e+00	666.00
IUUC-Ame-011102	Astyanax mexicanus	74.93	2.00e-145	508.00
IUUC-Bta-012529	Bos taurus	91.27	0.00e+00	1001.00
IUUC-Cja-019016	Callithrix jacchus	88.87	0.00e+00	993.00
IUUC-Cfa-020714	Canis familiaris	93.57	0.00e+00	1080.00
IUUC-Cpo-021727	Cavia porcellus	89.13	0.00e+00	1013.00
IUUC-Csa-023071	Chlorocebus sabaeus	98.27	0.00e+00	684.00
IUUC-Cin-025797	Ciona intestinalis	50.14	9.00e-94	336.00
IUUC-Csv-026132	Ciona savignyi	50.14	1.00e-97	350.00
IUUC-Dre-027872	Danio rerio	80.94	1.00e-161	562.00
IUUC-Dno-029329	Dasypus novemcinctus	91.10	0.00e+00	1038.00
IUUC-Dor-030574	Dipodomys ordii	92.75	0.00e+00	1020.00
IUUC-Dme-032208	Drosophila melanogaster	47.34	2.00e-82	300.00
IUUC-Ete-032725	Echinops telfairi	81.64	4.00e-173	601.00
IUUC-Eca-033361	Equus caballus	93.90	0.00e+00	1077.00
IUUC-Eeu-035272	Erinaceus europaeus	77.98	0.00e+00	687.00
IUUC-Fca-036497	Felis catus	93.90	0.00e+00	1077.00
IUUC-Fal-036766	Ficedula albicollis	62.75	0.00e+00	664.00
IUUC-Gmo-039129	Gadus morhua	67.40	3.00e-124	438.00
IUUC-Gga-040889	Gallus gallus	80.76	2.00e-147	516.00
IUUC-Gac-042475	Gasterosteus aculeatus	70.40	2.00e-138	484.00
IUUC-Ggo-044814	Gorilla gorilla	92.24	3.00e-177	614.00
IUUC-Hsa-045937	Homo sapiens	90.94	0.00e+00	1016.00
IUUC-Itr-048171	Ictidomys tridecemlineatus	92.50	0.00e+00	1068.00
IUUC-Lch-050527	Latimeria chalumnae	67.02	4.00e-178	617.00
IUUC-Loc-052697	Lepisosteus oculatus	78.57	1.00e-160	560.00
IUUC-Laf-054167	Loxodonta africana	86.56	0.00e+00	1005.00
IUUC-Mcc-055584	Macaca mulatta	91.76	0.00e+00	1057.00
IUUC-Meu-056542	Macropus eugenii	84.54	0.00e+00	927.00
IUUC-Mga-060020	Meleagris gallopavo	60.10	0.00e+00	637.00
IUUC-Mmr-060989	Microcebus murinus	93.08	0.00e+00	1071.00
IUUC-Mdo-062761	Monodelphis domestica	84.38	0.00e+00	926.00
IUUC-Mmu-063710	Mus musculus	90.63	0.00e+00	1065.00
IUUC-Mpu-066573	Mustela putorius furo	93.74	0.00e+00	1075.00
IUUC-Nle-070013	Nomascus leucogenys	91.18	0.00e+00	994.00
IUUC-Opr-070907	Ochotona princeps	95.06	0.00e+00	1072.00
IUUC-Ont-071944	Oreochromis niloticus	81.27	2.00e-163	568.00
IUUC-Oan-073105	Ornithorhynchus anatinus	82.08	1.00e-145	508.00
IUUC-Ola-087412	Oryzias latipes	69.57	1.00e-150	526.00
IUUC-Oga-088973	Otolemur garnettii	92.59	0.00e+00	1066.00
IUUC-Oar-089916	Ovis aries	91.93	0.00e+00	1039.00
IUUC-Ptr-090998	Pan troglodytes	91.27	0.00e+00	1025.00
IUUC-Pan-092686	Papio anubis	91.93	0.00e+00	1058.00
IUUC-Psi-093284	Pelodiscus sinensis	71.38	4.00e-124	437.00
IUUC-Pma-094462	Petromyzon marinus	64.71	2.00e-74	271.00
IUUC-Pno-094986	Phaeosphaeria nodorum	32.11	3.00e-39	157.00
IUUC-Pfo-097352	Poecilia formosa	79.14	1.00e-165	576.00
IUUC-Pab-098688	Pongo abelii	84.51	0.00e+00	914.00
IUUC-Pca-100205	Procavia capensis	93.37	0.00e+00	640.00
IUUC-Pva-103188	Pteropus vampyrus	92.09	0.00e+00	1030.00
IUUC-Rno-105853	Rattus norvegicus	90.95	0.00e+00	1063.00
IUUC-Sha-107237	Sarcophilus harrisii	83.72	0.00e+00	918.00
IUUC-Sar-113103	Sorex araneus	91.07	1.00e-180	625.00
IUUC-Ssc-115955	Sus scrofa	93.41	0.00e+00	1050.00
IUUC-Tgu-116894	Taeniopygia guttata	68.50	8.00e-179	619.00
IUUC-Tru-117703	Takifugu rubripes	65.50	1.00e-132	465.00
IUUC-Tsy-118879	Tarsius syrichta	96.20	0.00e+00	834.00
IUUC-Tni-119866	Tetraodon nigroviridis	78.30	4.00e-153	533.00
IUUC-Tbe-127367	Tupaia belangeri	84.94	0.00e+00	661.00
IUUC-Ttr-128773	Tursiops truncatus	90.44	0.00e+00	1033.00
IUUC-Vpa-130402	Vicugna pacos	82.71	0.00e+00	770.00
IUUC-Xtr-132658	Xenopus tropicalis	57.42	2.00e-178	619.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence