iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Pab-098688

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABGA01037582

Gene Name

USP2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000003966.1	ENSPPYT00000004722.1	ENSPPYP00000004544.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	4.70e-75	252.9	268	534

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelw.kskkkavsprellkalkkeaeefsgye 88
           Gl+NlgNtC+mNS+LQcLsn++elr+++l+  + ++l++   ++ +++l+++++kl++ +w +s + +vsp+e++++++++a++f gy+
   Q: 268  GLRNLGNTCFMNSILQCLSNTRELRDYCLQrLYMRDLHHG--SNAHTALMEEFAKLIQTIWtSSPSDVVSPSEFKTQIQRYAPRFVGYN 354
           9*****************************7778888776..67999**************889999********************** PP
   S: 89   qqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.....aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldl 172
           qqDaqEfl+flld+l++e+++ +  pk++ e+ d+     +      ++k  ++++s i dlF gqlks+++c +c+  s+ ++pf+dl
   Q: 355  QQDAQEFLRFLLDGLHNEVNRVTLRPKSNPENFDHLPD--DekgrqMWRKYLEREDSRIGDLFVGQLKSSLTCTDCGYCSTVFDPFWDL 441
           *******************9955555444444443222..2235559****************************************** PP
   S: 173  slpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ld 260
           slp+ ++    + +l dc++ ftke+ l+g++k  c +c++++++ kk++++++P++L+lhLkRf  se++ + +k+++ v+fpl+ Ld
   Q: 442  SLPIAKRGYP-EVTLMDCMRLFTKEDVLDGDEKPTCCRCRGRKRCIKKFSIQRFPKILVLHLKRF--SESRIRTSKLTTFVNFPLRdLD 527
           ******9976.779***************************************************..88899***************** PP
   S: 261  lspfcts 267
           l++f ++
   Q: 528  LREFASE 534
           ***9987 PP

Organism

Pongo abelii

Protein Sequence
(Fasta)

MSQLSSTLKR YTESARYTDA HYAKSGYGAY TPSSYGANLA ASLLEKDKLG FKPVPTSSFL 60
TRPRTYGPSS LLDYDRGRPL LRPDITGGGK RAESQTRGTE RPSGSGLSGG SGFPHGVTNN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCCCAGC TCTCCTCCAC CCTGAAGCGC TACACAGAAT CGGCCCGCTA CACAGATGCC 60
CACTATGCCA AGTCGGGCTA TGGTGCCTAC ACCCCCTCCT CCTATGGGGC CAACCTGGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005938--C:cell cortex
GO:0005634--C:nucleus
GO:0048471--C:perinuclear region of cytoplasm
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0032922--P:circadian regulation of gene expression
GO:0043153--P:entrainment of circadian clock by photoperiod
GO:0045475--P:locomotor rhythm
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0045931--P:positive regulation of mitotic cell cycle
GO:0016579--P:protein deubiquitination
GO:0050821--P:protein stabilization
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001988	Ailuropoda melanoleuca	86.14	0.00e+00	940.00
IUUC-Aca-005132	Anolis carolinensis	54.38	1.00e-157	549.00
IUUC-Ame-011102	Astyanax mexicanus	73.40	6.00e-115	407.00
IUUC-Bta-012529	Bos taurus	82.18	0.00e+00	874.00
IUUC-Cja-019016	Callithrix jacchus	86.39	0.00e+00	971.00
IUUC-Cfa-020714	Canis familiaris	86.47	0.00e+00	970.00
IUUC-Cpo-021727	Cavia porcellus	81.68	0.00e+00	877.00
IUUC-Csa-023071	Chlorocebus sabaeus	87.32	4.00e-160	557.00
IUUC-Dre-027872	Danio rerio	72.43	8.00e-136	476.00
IUUC-Dno-029329	Dasypus novemcinctus	83.99	0.00e+00	910.00
IUUC-Dor-030574	Dipodomys ordii	84.16	0.00e+00	896.00
IUUC-Ete-032725	Echinops telfairi	80.15	5.00e-164	570.00
IUUC-Eca-033361	Equus caballus	87.46	0.00e+00	958.00
IUUC-Eeu-035272	Erinaceus europaeus	77.73	0.00e+00	668.00
IUUC-Fca-036497	Felis catus	87.13	0.00e+00	956.00
IUUC-Fal-036766	Ficedula albicollis	57.91	3.00e-161	561.00
IUUC-Gmo-039129	Gadus morhua	61.35	3.00e-101	361.00
IUUC-Gga-040889	Gallus gallus	81.95	2.00e-125	442.00
IUUC-Gac-042475	Gasterosteus aculeatus	60.34	2.00e-108	385.00
IUUC-Ggo-044814	Gorilla gorilla	81.90	3.00e-140	491.00
IUUC-Hsa-045937	Homo sapiens	90.91	0.00e+00	971.00
IUUC-Itr-048171	Ictidomys tridecemlineatus	84.97	0.00e+00	952.00
IUUC-Lch-050527	Latimeria chalumnae	54.79	1.00e-145	509.00
IUUC-Loc-052697	Lepisosteus oculatus	68.00	2.00e-126	446.00
IUUC-Laf-054167	Loxodonta africana	79.77	0.00e+00	873.00
IUUC-Mcc-055584	Macaca mulatta	90.41	0.00e+00	1004.00
IUUC-Meu-056542	Macropus eugenii	78.25	0.00e+00	805.00
IUUC-Mga-060020	Meleagris gallopavo	54.19	5.00e-148	517.00
IUUC-Mmr-060989	Microcebus murinus	87.46	0.00e+00	957.00
IUUC-Mdo-062761	Monodelphis domestica	78.58	0.00e+00	813.00
IUUC-Mmu-063710	Mus musculus	82.07	0.00e+00	897.00
IUUC-Mpu-066573	Mustela putorius furo	86.96	0.00e+00	952.00
IUUC-Nle-070013	Nomascus leucogenys	97.76	0.00e+00	971.00
IUUC-Opr-070907	Ochotona princeps	83.20	0.00e+00	872.00
IUUC-Ont-071944	Oreochromis niloticus	72.33	5.00e-136	477.00
IUUC-Oan-073105	Ornithorhynchus anatinus	75.59	9.00e-115	406.00
IUUC-Ocu-073941	Oryctolagus cuniculus	84.84	0.00e+00	921.00
IUUC-Ola-087412	Oryzias latipes	62.08	3.00e-126	445.00
IUUC-Oga-088973	Otolemur garnettii	87.29	0.00e+00	957.00
IUUC-Oar-089916	Ovis aries	82.84	0.00e+00	917.00
IUUC-Ptr-090998	Pan troglodytes	91.24	0.00e+00	978.00
IUUC-Pan-092686	Papio anubis	90.58	0.00e+00	1005.00
IUUC-Psi-093284	Pelodiscus sinensis	73.77	5.00e-93	333.00
IUUC-Pma-094462	Petromyzon marinus	65.24	1.00e-70	258.00
IUUC-Pfo-097352	Poecilia formosa	69.94	4.00e-136	478.00
IUUC-Pca-100205	Procavia capensis	80.98	3.00e-144	505.00
IUUC-Pva-103188	Pteropus vampyrus	85.81	0.00e+00	907.00
IUUC-Rno-105853	Rattus norvegicus	83.33	0.00e+00	943.00
IUUC-Sha-107237	Sarcophilus harrisii	78.42	0.00e+00	809.00
IUUC-Sar-113103	Sorex araneus	80.12	2.00e-141	495.00
IUUC-Ssc-115955	Sus scrofa	84.65	0.00e+00	936.00
IUUC-Tgu-116894	Taeniopygia guttata	62.05	4.00e-144	504.00
IUUC-Tru-117703	Takifugu rubripes	57.89	2.00e-104	372.00
IUUC-Tsy-118879	Tarsius syrichta	87.67	0.00e+00	714.00
IUUC-Tni-119866	Tetraodon nigroviridis	76.41	1.00e-126	445.00
IUUC-Tbe-127367	Tupaia belangeri	83.25	0.00e+00	628.00
IUUC-Ttr-128773	Tursiops truncatus	82.67	0.00e+00	914.00
IUUC-Vpa-130402	Vicugna pacos	82.31	0.00e+00	759.00
IUUC-Xtr-132658	Xenopus tropicalis	51.29	7.00e-145	507.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence