iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Itr-048054

Ensembl Protein ID

ENSSTOP00000004283.2

UniProt Accession

I3M4U6; I3M4U6_ICTTR

Genbank Protein ID

ENSSTOP00000004283

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTP01106967

Gene Name

TNK2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000004761.2	ENSSTOT00000004770.2	ENSSTOP00000004283.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UBA	92.88	0.00e+00	1724.00	IUUC-Hsa-046670
UBD/Alpha-Helix/UBA	94.97	0.00e+00	1788.00	IUUC-Mmu-063861

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

MQPEEGTGWL LELLSEVQLQ QYFLRLRDDL NVTRLSHFEY VKNEDLEKIG MGRPGQRRLW 60
EAVKRRKAMC KRKSWMSKVF SGKRLEAEFP PHHSQSTFRK PSPTPGGPVG EGPLQSLTCL 120

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Nucleotide Sequence
(Fasta)

CACAGAGGCT GGGGAGCAGC AGCATGCAGC CAGAGGAGGG CACAGGCTGG TTGCTGGAGT 60
TGCTGTCTGA GGTGCAGCTA CAGCAATACT TCCTTCGTCT TCGGGATGAC CTCAATGTTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR015116--Cdc42_binding_dom-like
IPR011009--Kinase-like_dom
IPR021619--Mig-6
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50002--SH3

Pfam

PF09027--GTPase_binding
PF11555--Inhibitor_Mig-6
PF07714--Pkinase_Tyr
PF14604--SH3_9

PRINTS

PR00109--TYRKINASE

SMART

SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005905--C:clathrin-coated pit
GO:0030136--C:clathrin-coated vesicle
GO:0070436--C:Grb2-EGFR complex
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0004712--F:protein serine/threonine/tyrosine kinase activity
GO:0004713--F:protein tyrosine kinase activity
GO:0050731--P:positive regulation of peptidyl-tyrosine phosphorylation
GO:2000369--P:regulation of clathrin-dependent endocytosis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002166	Ailuropoda melanoleuca	92.34	0.00e+00	1672.00
IUUC-Aca-004315	Anolis carolinensis	88.97	1.00e-73	268.00
IUUC-Ame-011350	Astyanax mexicanus	54.14	0.00e+00	1040.00
IUUC-Bta-012325	Bos taurus	92.98	0.00e+00	1721.00
IUUC-Cel-018130	Caenorhabditis elegans	36.85	3.00e-89	323.00
IUUC-Cja-019545	Callithrix jacchus	87.11	0.00e+00	1563.00
IUUC-Cfa-020706	Canis familiaris	92.99	0.00e+00	1736.00
IUUC-Cpo-022032	Cavia porcellus	89.47	0.00e+00	1678.00
IUUC-Csa-023936	Chlorocebus sabaeus	94.69	0.00e+00	1724.00
IUUC-Csv-026328	Ciona savignyi	58.84	5.00e-173	600.00
IUUC-Dre-028714	Danio rerio	64.21	0.00e+00	1232.00
IUUC-Dno-029525	Dasypus novemcinctus	92.70	0.00e+00	1728.00
IUUC-Dme-031778	Drosophila melanogaster	56.12	3.00e-144	505.00
IUUC-Ete-032225	Echinops telfairi	90.63	0.00e+00	857.00
IUUC-Fca-035664	Felis catus	93.75	0.00e+00	1796.00
IUUC-Gmo-039543	Gadus morhua	58.47	0.00e+00	947.00
IUUC-Gga-040241	Gallus gallus	69.57	0.00e+00	1330.00
IUUC-Gac-041457	Gasterosteus aculeatus	62.36	0.00e+00	1133.00
IUUC-Ggo-045333	Gorilla gorilla	92.22	0.00e+00	1700.00
IUUC-Hsa-046670	Homo sapiens	92.88	0.00e+00	1669.00
IUUC-Lch-049670	Latimeria chalumnae	62.98	0.00e+00	1208.00
IUUC-Loc-052870	Lepisosteus oculatus	63.35	0.00e+00	1273.00
IUUC-Laf-053782	Loxodonta africana	92.41	0.00e+00	1701.00
IUUC-Mcc-055874	Macaca mulatta	94.88	0.00e+00	1719.00
IUUC-Mga-059717	Meleagris gallopavo	72.45	0.00e+00	1398.00
IUUC-Mdo-062270	Monodelphis domestica	86.65	0.00e+00	1615.00
IUUC-Mmu-063861	Mus musculus	94.97	0.00e+00	1818.00
IUUC-Mpu-066127	Mustela putorius furo	95.64	0.00e+00	1367.00
IUUC-Mlu-067937	Myotis lucifugus	83.36	0.00e+00	1640.00
IUUC-Nle-069298	Nomascus leucogenys	91.57	0.00e+00	1380.00
IUUC-Ont-072437	Oreochromis niloticus	58.80	0.00e+00	1202.00
IUUC-Oan-073708	Ornithorhynchus anatinus	75.31	6.00e-116	410.00
IUUC-Ola-087023	Oryzias latipes	60.91	0.00e+00	1144.00
IUUC-Pan-091857	Papio anubis	92.04	6.00e-92	329.00
IUUC-Psi-093401	Pelodiscus sinensis	54.95	4.00e-149	521.00
IUUC-Pfo-097455	Poecilia formosa	59.60	0.00e+00	1205.00
IUUC-Rno-105586	Rattus norvegicus	94.59	0.00e+00	1788.00
IUUC-Sha-106868	Sarcophilus harrisii	82.92	0.00e+00	1582.00
IUUC-Ssc-116250	Sus scrofa	92.42	0.00e+00	1662.00
IUUC-Tgu-116592	Taeniopygia guttata	70.97	0.00e+00	1325.00
IUUC-Tru-117852	Takifugu rubripes	70.46	4.00e-180	625.00
IUUC-Tsy-119087	Tarsius syrichta	98.51	2.00e-158	553.00
IUUC-Tni-120826	Tetraodon nigroviridis	62.88	0.00e+00	1231.00
IUUC-Xtr-132069	Xenopus tropicalis	66.05	0.00e+00	1191.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence