iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000000972.3	ENSMMUT00000045185.2	ENSMMUP00000038201.2
ENSMMUG00000000972.3	ENSMMUT00000045187.2	ENSMMUP00000038203.2
ENSMMUG00000000972.3	ENSMMUT00000001390.3	ENSMMUP00000001308.3
ENSMMUG00000000972.3	ENSMMUT00000068485.1	ENSMMUP00000056776.1
ENSMMUG00000000972.3	ENSMMUT00000070677.1	ENSMMUP00000050778.1
ENSMMUG00000000972.3	ENSMMUT00000075152.1	ENSMMUP00000043933.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	8.50e-06	26.8	975	1008

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 5    dkleqlveMGFdreealqaLraannnleaAveyL 38
           dk++ ++  G ++ee++ aL+++++++++A+ yL
   Q: 975  DKIQMAMVHGVTTEECQAALQSHGWSVQRAAQYL 1008
           89******************************99 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MQPEEGTGWL LELLSEVQLQ QYFLRLRDDL NVTRLSHFEY VKNEDLEKIG MGRPGQRRLW 60
EAVKRRKALC KRKSWMSKVF SGKRLEAEFP PHHSQSTFRK TSPAPGGPAG EGPLQSLTCL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTGGGCCCC AGGGGAGAGG AAGAGCTTCT GCCCTGGGAC TTCCTGTGCC GGCGATGGCC 60
TCGCGCCAGG GCTGGGCGCG GCACCCCCGC GTGGGCCCGT GTTGGGGCGG CTTTTCAGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR015116--Cdc42_binding_dom-like
IPR011009--Kinase-like_dom
IPR021619--Mig-6
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50002--SH3

Pfam

PF09027--GTPase_binding
PF11555--Inhibitor_Mig-6
PF07714--Pkinase_Tyr
PF14604--SH3_9

PRINTS

PR00109--TYRKINASE

SMART

SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005905--C:clathrin-coated pit
GO:0030136--C:clathrin-coated vesicle
GO:0070436--C:Grb2-EGFR complex
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0004712--F:protein serine/threonine/tyrosine kinase activity
GO:0004713--F:protein tyrosine kinase activity
GO:0050731--P:positive regulation of peptidyl-tyrosine phosphorylation
GO:2000369--P:regulation of clathrin-dependent endocytosis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002166	Ailuropoda melanoleuca	93.47	0.00e+00	1667.00
IUUC-Aca-004315	Anolis carolinensis	88.97	1.00e-73	268.00
IUUC-Ame-011350	Astyanax mexicanus	55.21	0.00e+00	1040.00
IUUC-Bta-012325	Bos taurus	93.83	0.00e+00	1724.00
IUUC-Cel-018130	Caenorhabditis elegans	36.96	2.00e-89	324.00
IUUC-Cja-019545	Callithrix jacchus	90.29	0.00e+00	1618.00
IUUC-Cfa-020706	Canis familiaris	93.37	0.00e+00	1733.00
IUUC-Cpo-022032	Cavia porcellus	90.04	0.00e+00	1672.00
IUUC-Csa-023936	Chlorocebus sabaeus	99.43	0.00e+00	1806.00
IUUC-Csv-026328	Ciona savignyi	58.84	4.00e-173	600.00
IUUC-Dre-028714	Danio rerio	63.51	0.00e+00	1215.00
IUUC-Dno-029525	Dasypus novemcinctus	94.21	0.00e+00	1747.00
IUUC-Dme-031778	Drosophila melanogaster	55.90	5.00e-144	505.00
IUUC-Ete-032225	Echinops telfairi	90.41	0.00e+00	854.00
IUUC-Fca-035664	Felis catus	94.41	0.00e+00	1795.00
IUUC-Gmo-039543	Gadus morhua	59.16	0.00e+00	944.00
IUUC-Gga-040241	Gallus gallus	67.89	0.00e+00	1299.00
IUUC-Gac-041457	Gasterosteus aculeatus	62.46	0.00e+00	1133.00
IUUC-Ggo-045333	Gorilla gorilla	96.11	0.00e+00	1763.00
IUUC-Hsa-046670	Homo sapiens	97.15	0.00e+00	1742.00
IUUC-Itr-048054	Ictidomys tridecemlineatus	94.88	0.00e+00	1770.00
IUUC-Lch-049670	Latimeria chalumnae	63.01	0.00e+00	1217.00
IUUC-Loc-052870	Lepisosteus oculatus	62.90	0.00e+00	1268.00
IUUC-Laf-053782	Loxodonta africana	92.60	0.00e+00	1690.00
IUUC-Mga-059717	Meleagris gallopavo	71.06	0.00e+00	1362.00
IUUC-Mdo-062270	Monodelphis domestica	86.37	0.00e+00	1616.00
IUUC-Mmu-063861	Mus musculus	94.97	0.00e+00	1802.00
IUUC-Mpu-066127	Mustela putorius furo	96.46	0.00e+00	1375.00
IUUC-Mlu-067937	Myotis lucifugus	91.87	0.00e+00	1344.00
IUUC-Nle-069298	Nomascus leucogenys	95.78	0.00e+00	1450.00
IUUC-Ont-072437	Oreochromis niloticus	58.89	0.00e+00	1191.00
IUUC-Oan-073708	Ornithorhynchus anatinus	74.07	1.00e-113	404.00
IUUC-Ola-087023	Oryzias latipes	61.31	0.00e+00	1135.00
IUUC-Pan-091857	Papio anubis	97.79	2.00e-97	348.00
IUUC-Psi-093401	Pelodiscus sinensis	55.15	3.00e-149	521.00
IUUC-Pfo-097455	Poecilia formosa	59.48	0.00e+00	1192.00
IUUC-Rno-105586	Rattus norvegicus	94.31	0.00e+00	1769.00
IUUC-Sha-106868	Sarcophilus harrisii	83.21	0.00e+00	1593.00
IUUC-Ssc-116250	Sus scrofa	93.65	0.00e+00	1665.00
IUUC-Tgu-116592	Taeniopygia guttata	70.62	0.00e+00	1317.00
IUUC-Tru-117852	Takifugu rubripes	70.25	5.00e-180	625.00
IUUC-Tsy-119087	Tarsius syrichta	98.51	1.00e-158	553.00
IUUC-Tni-120826	Tetraodon nigroviridis	63.27	0.00e+00	1226.00
IUUC-Xtr-132069	Xenopus tropicalis	65.76	0.00e+00	1187.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence