iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tgu-116592

Ensembl Protein ID

ENSTGUP00000009867.1

UniProt Accession

H0ZH03; H0ZH03_TAEGU

Genbank Protein ID

ENSTGUP00000009867

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABQF01023475

Gene Name

TNK2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTGUG00000009557.1	ENSTGUT00000009973.1	ENSTGUP00000009867.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	6.10e-08	32.4	929	953

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 14   GFdreealqaLraannnleaAveyL 38
           G ++ee+++aL+++++n+++A+ yL
   Q: 929  GVTTEECQTALQNHGWNVQRAIQYL 953
           899********************99 PP

Organism

Taeniopygia guttata

Protein Sequence
(Fasta)

MQAEEGTDWL LELLTELQLQ QYFLRIRDEL NVTRLSHFEY VKNEDLEKIG MGRPGQRRLW 60
EAVKRRKAMC KRKSWMSKVF SGKRPESELP PQPQSTFRKP PTPPPPEAGG QHSLTCLVRE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCAGGCGG AGGAGGGCAC GGACTGGCTG CTGGAGCTGC TCACCGAGCT GCAGCTGCAG 60
CAGTACTTCC TGCGCATCCG AGACGAGCTC AACGTCACAC GCCTCTCCCA CTTTGAGTAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR015116--Cdc42_binding_dom-like
IPR011009--Kinase-like_dom
IPR021619--Mig-6
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom
IPR009060--UBA-like

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50002--SH3

Pfam

PF09027--GTPase_binding
PF11555--Inhibitor_Mig-6
PF07714--Pkinase_Tyr
PF14604--SH3_9

PRINTS

PR00109--TYRKINASE

SMART

SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005905--C:clathrin-coated pit
GO:0030136--C:clathrin-coated vesicle
GO:0070436--C:Grb2-EGFR complex
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0004712--F:protein serine/threonine/tyrosine kinase activity
GO:0004713--F:protein tyrosine kinase activity
GO:0050731--P:positive regulation of peptidyl-tyrosine phosphorylation
GO:2000369--P:regulation of clathrin-dependent endocytosis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002166	Ailuropoda melanoleuca	69.06	0.00e+00	1235.00
IUUC-Aca-004315	Anolis carolinensis	94.85	3.00e-78	283.00
IUUC-Ame-011350	Astyanax mexicanus	57.94	0.00e+00	1083.00
IUUC-Bta-012325	Bos taurus	69.14	0.00e+00	1274.00
IUUC-Cel-018130	Caenorhabditis elegans	38.11	3.00e-90	326.00
IUUC-Cja-019545	Callithrix jacchus	65.42	0.00e+00	1166.00
IUUC-Cfa-020706	Canis familiaris	68.32	0.00e+00	1269.00
IUUC-Cpo-022032	Cavia porcellus	69.38	0.00e+00	1253.00
IUUC-Csa-023936	Chlorocebus sabaeus	70.33	0.00e+00	1274.00
IUUC-Csv-026328	Ciona savignyi	58.67	1.00e-168	585.00
IUUC-Dre-028714	Danio rerio	68.11	0.00e+00	1321.00
IUUC-Dno-029525	Dasypus novemcinctus	69.60	0.00e+00	1268.00
IUUC-Dme-031778	Drosophila melanogaster	55.38	3.00e-140	492.00
IUUC-Ete-032225	Echinops telfairi	78.43	0.00e+00	740.00
IUUC-Fca-035664	Felis catus	69.16	0.00e+00	1290.00
IUUC-Gmo-039543	Gadus morhua	58.39	0.00e+00	957.00
IUUC-Gga-040241	Gallus gallus	84.48	0.00e+00	1641.00
IUUC-Gac-041457	Gasterosteus aculeatus	64.37	0.00e+00	1206.00
IUUC-Ggo-045333	Gorilla gorilla	70.54	0.00e+00	1259.00
IUUC-Hsa-046670	Homo sapiens	68.91	0.00e+00	1238.00
IUUC-Itr-048054	Ictidomys tridecemlineatus	70.68	0.00e+00	1276.00
IUUC-Lch-049670	Latimeria chalumnae	69.81	0.00e+00	1376.00
IUUC-Loc-052870	Lepisosteus oculatus	71.67	0.00e+00	1433.00
IUUC-Laf-053782	Loxodonta africana	68.06	0.00e+00	1214.00
IUUC-Mcc-055874	Macaca mulatta	70.14	0.00e+00	1263.00
IUUC-Mga-059717	Meleagris gallopavo	87.84	0.00e+00	1701.00
IUUC-Mdo-062270	Monodelphis domestica	68.21	0.00e+00	1273.00
IUUC-Mmu-063861	Mus musculus	70.14	0.00e+00	1292.00
IUUC-Mpu-066127	Mustela putorius furo	76.87	0.00e+00	1055.00
IUUC-Mlu-067937	Myotis lucifugus	65.58	0.00e+00	1239.00
IUUC-Nle-069298	Nomascus leucogenys	66.56	0.00e+00	1014.00
IUUC-Ont-072437	Oreochromis niloticus	61.51	0.00e+00	1285.00
IUUC-Oan-073708	Ornithorhynchus anatinus	61.61	1.00e-87	317.00
IUUC-Ola-087023	Oryzias latipes	63.55	0.00e+00	1176.00
IUUC-Pan-091857	Papio anubis	59.09	5.00e-63	233.00
IUUC-Psi-093401	Pelodiscus sinensis	56.28	3.00e-145	508.00
IUUC-Pfo-097455	Poecilia formosa	63.41	0.00e+00	1273.00
IUUC-Rno-105586	Rattus norvegicus	69.19	0.00e+00	1277.00
IUUC-Sha-106868	Sarcophilus harrisii	73.86	0.00e+00	1061.00
IUUC-Ssc-116250	Sus scrofa	68.66	0.00e+00	1234.00
IUUC-Tru-117852	Takifugu rubripes	72.94	0.00e+00	656.00
IUUC-Tsy-119087	Tarsius syrichta	86.11	1.00e-148	520.00
IUUC-Tni-120826	Tetraodon nigroviridis	65.90	0.00e+00	1303.00
IUUC-Xtr-132069	Xenopus tropicalis	75.20	0.00e+00	1350.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence