iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mcc-054993

Ensembl Protein ID

ENSMMUP00000028638.3

UniProt Accession

F7DXU8; F7DXU8_MACMU

Genbank Protein ID

ENSMMUP00000028638

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

JSUE03006367

Gene Name

KLHL42

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000021742.3	ENSMMUT00000030598.3	ENSMMUP00000028638.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/BCR/BTB_3-box	99.72	0.00e+00	640.00	IUUC-Hsa-046283

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MSAEEMVQIR LEDRCYPVSK RKLIEQSDYF RALYRSGMRE ALSQEAGGPE VQQLRGLSAP 60
GLRLVLDFIN AGGAREGWLL GPRGEKGGGV DEDEEMDEVS LLSELVEAAS FLQVTSLLQL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCGGCCG AGGAGATGGT GCAGATCCGC CTGGAGGATC GCTGCTACCC GGTGAGCAAG 60
AGGAAGCTCA TCGAGCAAAG CGACTACTTC CGCGCCCTCT ACCGCTCCGG CATGCGCGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF01344--Kelch_1

SMART

SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0004842--F:ubiquitin-protein transferase activity
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination
GO:0032886--P:regulation of microtubule-based process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002285	Ailuropoda melanoleuca	94.93	5.00e-180	624.00
IUUC-Apl-004005	Anas platyrhynchos	65.83	7.00e-104	370.00
IUUC-Aca-004932	Anolis carolinensis	57.92	6.00e-63	234.00
IUUC-Ame-011389	Astyanax mexicanus	56.78	2.00e-104	372.00
IUUC-Bta-013120	Bos taurus	92.98	1.00e-168	586.00
IUUC-Cfa-020969	Canis familiaris	95.77	5.00e-178	617.00
IUUC-Cpo-022181	Cavia porcellus	80.28	4.00e-151	528.00
IUUC-Csa-023917	Chlorocebus sabaeus	99.72	0.00e+00	640.00
IUUC-Cho-024950	Choloepus hoffmanni	97.46	7.00e-177	612.00
IUUC-Dre-028648	Danio rerio	54.80	2.00e-102	365.00
IUUC-Dno-028937	Dasypus novemcinctus	70.09	8.00e-121	427.00
IUUC-Dor-031019	Dipodomys ordii	81.72	3.00e-111	395.00
IUUC-Ete-032490	Echinops telfairi	82.90	6.00e-151	527.00
IUUC-Eca-033326	Equus caballus	92.63	0.00e+00	628.00
IUUC-Eeu-034985	Erinaceus europaeus	90.28	2.00e-32	133.00
IUUC-Fca-035493	Felis catus	98.65	1.00e-132	466.00
IUUC-Fal-036818	Ficedula albicollis	63.67	4.00e-83	301.00
IUUC-Gmo-039278	Gadus morhua	49.00	3.00e-56	211.00
IUUC-Gga-040470	Gallus gallus	65.27	3.00e-102	365.00
IUUC-Gac-041998	Gasterosteus aculeatus	54.37	2.00e-99	356.00
IUUC-Ggo-045547	Gorilla gorilla	99.72	0.00e+00	635.00
IUUC-Hsa-046283	Homo sapiens	99.72	0.00e+00	640.00
IUUC-Itr-048418	Ictidomys tridecemlineatus	95.49	0.00e+00	656.00
IUUC-Lch-049748	Latimeria chalumnae	56.25	2.00e-98	353.00
IUUC-Loc-052270	Lepisosteus oculatus	56.34	4.00e-102	365.00
IUUC-Laf-054165	Loxodonta africana	90.00	4.00e-123	434.00
IUUC-Meu-056500	Macropus eugenii	84.32	8.00e-93	333.00
IUUC-Mga-059376	Meleagris gallopavo	66.10	8.00e-109	387.00
IUUC-Mmr-060782	Microcebus murinus	96.62	0.00e+00	647.00
IUUC-Mdo-062068	Monodelphis domestica	78.87	1.00e-134	473.00
IUUC-Mmu-064288	Mus musculus	88.45	4.00e-166	577.00
IUUC-Mpu-065815	Mustela putorius furo	97.18	0.00e+00	647.00
IUUC-Mlu-067560	Myotis lucifugus	90.83	4.00e-174	604.00
IUUC-Nle-069737	Nomascus leucogenys	99.72	0.00e+00	640.00
IUUC-Opr-070332	Ochotona princeps	83.06	7.00e-161	560.00
IUUC-Ont-072368	Oreochromis niloticus	55.49	2.00e-94	339.00
IUUC-Ocu-074509	Oryctolagus cuniculus	94.08	2.00e-173	602.00
IUUC-Ola-087330	Oryzias latipes	52.68	2.00e-95	342.00
IUUC-Oga-089095	Otolemur garnettii	98.59	0.00e+00	639.00
IUUC-Oar-090108	Ovis aries	98.19	1.00e-96	346.00
IUUC-Ptr-091031	Pan troglodytes	99.72	0.00e+00	640.00
IUUC-Pan-091834	Papio anubis	99.72	0.00e+00	637.00
IUUC-Psi-093483	Pelodiscus sinensis	62.10	7.00e-87	314.00
IUUC-Pfo-097126	Poecilia formosa	56.06	6.00e-101	360.00
IUUC-Pab-098446	Pongo abelii	99.44	0.00e+00	640.00
IUUC-Pca-100423	Procavia capensis	95.77	8.00e-175	606.00
IUUC-Pva-102436	Pteropus vampyrus	97.27	7.00e-113	400.00
IUUC-Rno-105244	Rattus norvegicus	88.17	3.00e-166	578.00
IUUC-Sha-107215	Sarcophilus harrisii	77.94	2.00e-141	495.00
IUUC-Ssc-115433	Sus scrofa	95.49	2.00e-177	615.00
IUUC-Tgu-116589	Taeniopygia guttata	63.81	2.00e-102	365.00
IUUC-Tru-118575	Takifugu rubripes	54.65	4.00e-99	355.00
IUUC-Tsy-118895	Tarsius syrichta	96.02	1.00e-130	459.00
IUUC-Tni-119944	Tetraodon nigroviridis	54.93	1.00e-99	356.00
IUUC-Ttr-128828	Tursiops truncatus	96.81	2.00e-107	382.00
IUUC-Vpa-130506	Vicugna pacos	98.02	1.00e-118	419.00
IUUC-Xtr-131850	Xenopus tropicalis	43.30	2.00e-59	223.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence