iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ptr-090916

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AACZ03120521

Gene Name

CDC34

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000010153.4	ENSPTRT00000018621.4	ENSPTRP00000017246.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	6.00e-46	155.6	15	152

Active Site

Position(s)	Description	Evidence
92	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 4    kelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilk..... 87
            elk l+++p+eg+++++v+  dl+++ev+i+Gp++t+Yegg+Fk++++fp dYP++PP ++fltk++hPn+ye+G+vC+sil+     
   Q: 15   LELKGLQEEPVEGFRVTLVEG-DLYNLEVAIFGPPNTYYEGGYFKARLKFPIDYPYSPPAFRFLTKMWHPNIYETGDVCISILHppvdd 102
           599******************.9************************************************************999999 PP
   S: 88   ......eeekWspalsvesvllsiqsllaepnpesplneeaaellkknre 131
                 ++e+W+p+++v+++lls++sll+epn+ sp+n++a+ +++k++e
   Q: 103  pqsgelPSERWNPTQNVRTILLSVISLLNEPNTFSPANVDASVMYRKWKE 152
           999*9******************************************998 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MARPLVPSSQ KALLLELKGL QEEPVEGFRV TLVEGDLYNL EVAIFGPPNT YYEGGYFKAR 60
LKFPIDYPYS PPAFRFLTKM WHPNIYETGD VCISILHPPV DDPQSGELPS ERWNPTQNVR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCAAGCGCC GGTGGGGCGG CGGCGCCAGA GCTGCTGGAG CGCTCGGGGT CCCCGGGCGG 60
CGGCGGCGGC GCAGAGGAGG AGGCAGGCGG CGGCCCCGGT GGCTCTCCCC CGGACGGTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0016607--C:nuclear speck
GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0035458--P:cellular response to interferon-beta
GO:0043951--P:negative regulation of cAMP-mediated signaling
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0070936--P:protein K48-linked ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001600	Ailuropoda melanoleuca	97.77	2.00e-125	441.00
IUUC-Bta-012516	Bos taurus	98.54	3.00e-117	414.00
IUUC-Cja-018852	Callithrix jacchus	89.05	2.00e-100	357.00
IUUC-Cfa-020203	Canis familiaris	99.03	1.00e-117	414.00
IUUC-Cpo-022139	Cavia porcellus	91.23	3.00e-117	413.00
IUUC-Csa-023371	Chlorocebus sabaeus	99.03	1.00e-117	415.00
IUUC-Dor-030875	Dipodomys ordii	94.67	4.00e-118	416.00
IUUC-Fca-035832	Felis catus	97.59	3.00e-93	333.00
IUUC-Gga-040694	Gallus gallus	92.37	1.00e-118	418.00
IUUC-Ggo-044806	Gorilla gorilla	99.03	8.00e-118	416.00
IUUC-Hsa-046245	Homo sapiens	99.03	1.00e-117	415.00
IUUC-Kpa-049316	Komagataella pastoris	48.09	8.00e-26	110.00
IUUC-Loc-052932	Lepisosteus oculatus	90.55	4.00e-108	383.00
IUUC-Mcc-054665	Macaca mulatta	96.10	7.00e-113	399.00
IUUC-Mga-060075	Meleagris gallopavo	91.95	3.00e-118	417.00
IUUC-Mmr-061165	Microcebus murinus	97.76	7.00e-119	419.00
IUUC-Mdo-061825	Monodelphis domestica	98.54	4.00e-117	413.00
IUUC-Mmu-064168	Mus musculus	98.65	3.00e-118	417.00
IUUC-Mpu-066009	Mustela putorius furo	97.77	3.00e-125	440.00
IUUC-Opr-070826	Ochotona princeps	87.91	7.00e-104	369.00
IUUC-Ont-071745	Oreochromis niloticus	89.16	2.00e-107	381.00
IUUC-Oan-073287	Ornithorhynchus anatinus	88.98	3.00e-115	407.00
IUUC-Ocu-074902	Oryctolagus cuniculus	94.66	3.00e-113	400.00
IUUC-Oga-088845	Otolemur garnettii	96.41	1.00e-123	435.00
IUUC-Pan-092577	Papio anubis	99.03	1.00e-117	415.00
IUUC-Psi-093039	Pelodiscus sinensis	90.45	3.00e-87	313.00
IUUC-Pab-098200	Pongo abelii	98.93	1.00e-106	378.00
IUUC-Pca-100169	Procavia capensis	86.43	4.00e-66	243.00
IUUC-Pva-102875	Pteropus vampyrus	100.00	3.00e-85	306.00
IUUC-Rno-106079	Rattus norvegicus	98.65	3.00e-118	417.00
IUUC-Ssc-115699	Sus scrofa	88.71	4.00e-88	316.00
IUUC-Tgu-117466	Taeniopygia guttata	90.68	2.00e-116	411.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence