iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pma-094311

Ensembl Protein ID

ENSPMAP00000001376.1

UniProt Accession

S4R845; S4R845_PETMA

Protein Name

Tyrosine-protein kinase

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPMAG00000001235.1	ENSPMAT00000001382.1	ENSPMAP00000001376.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	7.80e-15	53.8	68	122

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 6    vqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           v +lydy++ + d+L +++Gd++ ++   e+ ++W+k+ + +++k+G +P+nFv+k++
   Q: 68   VVALYDYDPIHADDLCFRRGDQLVIV---EEGNDWWKARSVATKKEGYIPSNFVAKVN 122
           899***********************...8899***********************97 PP

Organism

Petromyzon marinus

Protein Sequence
(Fasta)

MGCSQSTEVE DYSASDVNKY VESSYFAVML STKTVDPNTC GVSEIRTPTI TTLEGSGFPN 60
RYVDGLLVVA LYDYDPIHAD DLCFRRGDQL VIVEEGNDWW KARSVATKKE GYIPSNFVAK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAACAGTGTA TTCAATGATC CGTGTTCCCG CTTCCGAATG GGAAACCAAA GTGCTTAGGA 60
GCCAATTGGC TTAGGGTTTA ACTTGACTTT CACGATTTAA GAAACTGCCA ACAAGCATTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001284	Ailuropoda melanoleuca	68.36	0.00e+00	738.00
IUUC-Apl-003285	Anas platyrhynchos	71.94	0.00e+00	685.00
IUUC-Aca-004724	Anolis carolinensis	71.02	0.00e+00	676.00
IUUC-Ame-011954	Astyanax mexicanus	73.26	0.00e+00	682.00
IUUC-Bta-013060	Bos taurus	69.94	0.00e+00	740.00
IUUC-Cja-019817	Callithrix jacchus	75.39	0.00e+00	738.00
IUUC-Cfa-020511	Canis familiaris	74.72	0.00e+00	734.00
IUUC-Cpo-022538	Cavia porcellus	68.30	0.00e+00	734.00
IUUC-Csa-024143	Chlorocebus sabaeus	73.40	0.00e+00	735.00
IUUC-Dre-028157	Danio rerio	66.54	0.00e+00	705.00
IUUC-Dno-029761	Dasypus novemcinctus	75.23	0.00e+00	733.00
IUUC-Dor-030892	Dipodomys ordii	64.11	0.00e+00	660.00
IUUC-Eca-034090	Equus caballus	73.42	0.00e+00	702.00
IUUC-Eeu-035004	Erinaceus europaeus	57.34	2.00e-141	493.00
IUUC-Fca-035937	Felis catus	67.45	0.00e+00	706.00
IUUC-Fal-036624	Ficedula albicollis	69.41	0.00e+00	694.00
IUUC-Gmo-039009	Gadus morhua	72.30	0.00e+00	699.00
IUUC-Gga-040997	Gallus gallus	64.53	0.00e+00	692.00
IUUC-Gac-042362	Gasterosteus aculeatus	72.13	0.00e+00	697.00
IUUC-Ggo-044570	Gorilla gorilla	75.73	0.00e+00	734.00
IUUC-Hsa-046378	Homo sapiens	75.73	0.00e+00	734.00
IUUC-Itr-048695	Ictidomys tridecemlineatus	74.23	0.00e+00	731.00
IUUC-Lch-049568	Latimeria chalumnae	71.27	0.00e+00	674.00
IUUC-Loc-052904	Lepisosteus oculatus	68.03	0.00e+00	726.00
IUUC-Laf-053654	Loxodonta africana	68.24	0.00e+00	736.00
IUUC-Mcc-055317	Macaca mulatta	68.67	0.00e+00	743.00
IUUC-Meu-056879	Macropus eugenii	62.26	0.00e+00	650.00
IUUC-Mga-059971	Meleagris gallopavo	69.66	0.00e+00	691.00
IUUC-Mmr-061510	Microcebus murinus	72.35	0.00e+00	747.00
IUUC-Mdo-062035	Monodelphis domestica	73.99	0.00e+00	707.00
IUUC-Mmu-064037	Mus musculus	71.67	0.00e+00	735.00
IUUC-Mpu-066874	Mustela putorius furo	74.94	0.00e+00	736.00
IUUC-Mlu-068202	Myotis lucifugus	72.75	0.00e+00	706.00
IUUC-Nle-069222	Nomascus leucogenys	75.39	0.00e+00	738.00
IUUC-Opr-070705	Ochotona princeps	75.28	0.00e+00	736.00
IUUC-Ont-072347	Oreochromis niloticus	73.71	0.00e+00	689.00
IUUC-Oan-073193	Ornithorhynchus anatinus	62.88	0.00e+00	677.00
IUUC-Ocu-074490	Oryctolagus cuniculus	74.05	0.00e+00	731.00
IUUC-Ola-086521	Oryzias latipes	73.03	0.00e+00	706.00
IUUC-Oga-088153	Otolemur garnettii	75.06	0.00e+00	730.00
IUUC-Oar-090184	Ovis aries	69.52	0.00e+00	734.00
IUUC-Ptr-090505	Pan troglodytes	71.59	0.00e+00	684.00
IUUC-Pan-092260	Papio anubis	73.62	0.00e+00	741.00
IUUC-Psi-093685	Pelodiscus sinensis	68.45	0.00e+00	673.00
IUUC-Pfo-096566	Poecilia formosa	66.22	0.00e+00	712.00
IUUC-Pva-103021	Pteropus vampyrus	67.65	0.00e+00	733.00
IUUC-Rno-105309	Rattus norvegicus	69.94	0.00e+00	739.00
IUUC-Sha-107099	Sarcophilus harrisii	69.33	0.00e+00	706.00
IUUC-Ssc-115624	Sus scrofa	65.10	0.00e+00	682.00
IUUC-Tgu-116912	Taeniopygia guttata	70.45	0.00e+00	695.00
IUUC-Tru-118449	Takifugu rubripes	73.20	0.00e+00	691.00
IUUC-Tbe-128144	Tupaia belangeri	67.56	0.00e+00	649.00
IUUC-Ttr-128457	Tursiops truncatus	65.17	0.00e+00	627.00
IUUC-Xtr-132224	Xenopus tropicalis	63.33	0.00e+00	664.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence