iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aml-001992

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Putative uncharacterized protein

Genbank Nucleotide ID

ACTA01060052

Gene Name

RNF125; PANDA_014196

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000009923.1	ENSAMET00000010880.1	ENSAMEP00000010427.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	1.30e-10	41.3	33	98
E3 activity/RING/RING	1.40e-08	35.2	37	76

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 4    eeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqawc 69
             f C++ le+ ++Pv + +G+++ rs+I+  l++++ tcP +r+ l +e +    + +r+ +++ 
   Q: 33   TSFDCSVCLEVLHQPVRTRCGHVFCRSCIATSLKNNKWTCPYCRAYLPSEGVPATDVAKRMRSEYQ 98
           579******************************99999*********9999999999999998875 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           C++Cle + + p+ ++CgHvf+++C+   +      ++++++CP+Cr
   Q: 37   CSVCLEVLHQ-PVRTRCGHVFCRSCIaTSL------KNNKWTCPYCR 76
           ********99.777***********95555......**********8 PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

MGSVLSSDSG KSAPASAAPR ALERKGDPEL PVTSFDCSVC LEVLHQPVRT RCGHVFCRSC 60
IATSLKNNKW TCPYCRAYLP SEGVPATDVA KRMRSEYQNC TECDTLVCLS EMRAHIRSCQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGCTCCG TGCTGAGCAG CGATAGCGGC AAATCCGCCC CCGCCTCGGC CGCCCCGCGG 60
GCCCTGGAGC GCAAGGGGGA CCCCGAGCTG CCCGTCACGT CCTTCGACTG CTCCGTGTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR008598--Di19_Zn_binding_dom
IPR034734--ZF_C2HC_RNF
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51803--ZF_C2HC_RNF
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF05605--zf-Di19

SMART

SM00184--RING

Gene Ontology

GO:0000139--C:Golgi membrane
GO:0034098--C:VCP-NPL4-UFD1 AAA ATPase complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0039536--P:negative regulation of RIG-I signaling pathway
GO:0032480--P:negative regulation of type I interferon production
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

KEGG

aml:100473812

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aca-004839	Anolis carolinensis	63.13	2.00e-67	247.00
IUUC-Bta-012827	Bos taurus	90.95	3.00e-120	423.00
IUUC-Cja-018794	Callithrix jacchus	91.81	3.00e-121	427.00
IUUC-Cfa-021234	Canis familiaris	96.98	6.00e-124	436.00
IUUC-Cpo-022412	Cavia porcellus	81.47	9.00e-107	379.00
IUUC-Csa-023406	Chlorocebus sabaeus	92.24	1.00e-122	431.00
IUUC-Cho-024427	Choloepus hoffmanni	75.71	8.00e-75	272.00
IUUC-Dno-030085	Dasypus novemcinctus	91.38	3.00e-121	427.00
IUUC-Dor-030911	Dipodomys ordii	70.26	6.00e-71	259.00
IUUC-Ete-032469	Echinops telfairi	85.78	3.00e-115	407.00
IUUC-Eca-034352	Equus caballus	94.40	1.00e-124	438.00
IUUC-Eeu-034889	Erinaceus europaeus	78.45	5.00e-97	346.00
IUUC-Fca-036116	Felis catus	96.98	2.00e-123	434.00
IUUC-Hsa-046518	Homo sapiens	91.81	5.00e-122	429.00
IUUC-Itr-048344	Ictidomys tridecemlineatus	95.48	3.00e-100	357.00
IUUC-Laf-053363	Loxodonta africana	91.45	2.00e-121	427.00
IUUC-Meu-056101	Macropus eugenii	79.15	1.00e-96	345.00
IUUC-Mdo-062046	Monodelphis domestica	75.54	1.00e-99	355.00
IUUC-Mmu-063184	Mus musculus	81.43	1.00e-56	211.00
IUUC-Mpu-065708	Mustela putorius furo	96.12	5.00e-126	442.00
IUUC-Mlu-067561	Myotis lucifugus	88.14	4.00e-93	333.00
IUUC-Nle-069665	Nomascus leucogenys	91.12	2.00e-110	390.00
IUUC-Opr-070301	Ochotona princeps	80.17	4.00e-101	360.00
IUUC-Ocu-074562	Oryctolagus cuniculus	92.06	5.00e-66	242.00
IUUC-Oga-088958	Otolemur garnettii	92.67	5.00e-123	433.00
IUUC-Oar-089541	Ovis aries	90.96	7.00e-96	342.00
IUUC-Ptr-090989	Pan troglodytes	92.24	5.00e-123	432.00
IUUC-Pan-092372	Papio anubis	91.38	8.00e-122	429.00
IUUC-Pab-098718	Pongo abelii	79.31	2.00e-97	347.00
IUUC-Pca-100453	Procavia capensis	89.66	1.00e-119	421.00
IUUC-Pva-102931	Pteropus vampyrus	92.24	7.00e-116	409.00
IUUC-Rno-105771	Rattus norvegicus	87.26	2.00e-100	358.00
IUUC-Sha-107557	Sarcophilus harrisii	74.68	2.00e-102	364.00
IUUC-Sar-113435	Sorex araneus	96.03	2.00e-69	253.00
IUUC-Ssc-116388	Sus scrofa	93.97	3.00e-125	440.00
IUUC-Tsy-119439	Tarsius syrichta	92.66	5.00e-98	349.00
IUUC-Tbe-127417	Tupaia belangeri	63.73	3.00e-68	251.00
IUUC-Ttr-129212	Tursiops truncatus	94.40	4.00e-125	440.00
IUUC-Vpa-130153	Vicugna pacos	91.38	2.00e-122	430.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence