iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Csa-023406

Ensembl Protein ID

ENSCSAP00000013888.1

UniProt Accession

A0A0D9RZ49; A0A0D9RZ49_CHLSB

Genbank Protein ID

ENSCSAP00000013888

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AQIB01127852

Gene Name

RNF125

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCSAG00000017870.1	ENSCSAT00000015963.1	ENSCSAP00000013888.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	3.50e-09	37.0	37	76
E3 activity/RING/U-box	1.30e-10	41.2	33	98

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           Ca+Cle + + p+ ++CgHvf+++C+   +      ++++++CP+Cr
   Q: 37   CAVCLEVLHQ-PVRTRCGHVFCRSCIaTSL------KNNKWTCPYCR 76
           ********99.777***********95555......**********8 PP

E3 activity/RING/U-box

   S: 4    eeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqawc 69
             f C++ le+ ++Pv + +G+++ rs+I+  l++++ tcP +r+ l +e +    + +r+ +++ 
   Q: 33   TSFDCAVCLEVLHQPVRTRCGHVFCRSCIATSLKNNKWTCPYCRAYLPSEGVPATDVAKRMKSEYK 98
           579******************************99999**********999999999999999986 PP

Organism

Chlorocebus sabaeus

Protein Sequence
(Fasta)

MGSVLSSDSG KSAPPSATPR ALERRGDPEL PVTSFDCAVC LEVLHQPVRT RCGHVFCRSC 60
IATSLKNNKW TCPYCRAYLP SEGVPATDVA KRMKSEYKNC AECDTLVCLS EMRAHIRTCQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGGTCCG TGCTGAGCAG CGACAGCGGC AAATCGGCTC CCCCCTCTGC CACCCCGCGG 60
GCCCTGGAGC GCAGGGGGGA CCCGGAGTTG CCCGTCACGT CCTTCGACTG CGCCGTGTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR008598--Di19_Zn_binding_dom
IPR034734--ZF_C2HC_RNF
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51803--ZF_C2HC_RNF
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF05605--zf-Di19

SMART

SM00184--RING

Gene Ontology

GO:0000139--C:Golgi membrane
GO:0034098--C:VCP-NPL4-UFD1 AAA ATPase complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0039536--P:negative regulation of RIG-I signaling pathway
GO:0032480--P:negative regulation of type I interferon production
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

KEGG

csab:103222569

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001992	Ailuropoda melanoleuca	92.24	4.00e-128	449.00
IUUC-Aca-004839	Anolis carolinensis	63.48	2.00e-67	247.00
IUUC-Bta-012827	Bos taurus	90.48	3.00e-125	440.00
IUUC-Cja-018794	Callithrix jacchus	93.97	8.00e-129	452.00
IUUC-Cfa-021234	Canis familiaris	91.38	2.00e-118	417.00
IUUC-Cpo-022412	Cavia porcellus	80.17	2.00e-107	381.00
IUUC-Cho-024427	Choloepus hoffmanni	76.27	6.00e-75	272.00
IUUC-Dno-030085	Dasypus novemcinctus	91.81	2.00e-126	444.00
IUUC-Dor-030911	Dipodomys ordii	70.69	3.00e-77	281.00
IUUC-Ete-032469	Echinops telfairi	86.21	5.00e-119	419.00
IUUC-Eca-034352	Equus caballus	93.53	5.00e-129	452.00
IUUC-Eeu-034889	Erinaceus europaeus	78.02	2.00e-102	364.00
IUUC-Fca-036116	Felis catus	92.67	3.00e-121	427.00
IUUC-Hsa-046518	Homo sapiens	96.98	7.00e-132	462.00
IUUC-Itr-048344	Ictidomys tridecemlineatus	95.48	2.00e-99	353.00
IUUC-Laf-053363	Loxodonta africana	91.88	2.00e-126	444.00
IUUC-Meu-056101	Macropus eugenii	78.20	3.00e-95	340.00
IUUC-Mdo-062046	Monodelphis domestica	74.68	7.00e-100	356.00
IUUC-Mmu-063184	Mus musculus	86.43	9.00e-60	221.00
IUUC-Mpu-065708	Mustela putorius furo	90.09	6.00e-125	439.00
IUUC-Mlu-067561	Myotis lucifugus	89.83	8.00e-94	335.00
IUUC-Nle-069665	Nomascus leucogenys	96.26	7.00e-121	426.00
IUUC-Opr-070301	Ochotona princeps	79.74	4.00e-106	377.00
IUUC-Ocu-074562	Oryctolagus cuniculus	92.06	2.00e-66	243.00
IUUC-Oga-088958	Otolemur garnettii	93.53	8.00e-129	452.00
IUUC-Oar-089541	Ovis aries	91.48	8.00e-96	342.00
IUUC-Ptr-090989	Pan troglodytes	97.41	8.00e-133	465.00
IUUC-Pan-092372	Papio anubis	99.14	8.00e-136	475.00
IUUC-Pab-098718	Pongo abelii	82.76	2.00e-106	377.00
IUUC-Pca-100453	Procavia capensis	90.52	6.00e-124	436.00
IUUC-Pva-102931	Pteropus vampyrus	92.67	1.00e-119	421.00
IUUC-Rno-105771	Rattus norvegicus	88.21	2.00e-101	360.00
IUUC-Sha-107557	Sarcophilus harrisii	75.11	9.00e-106	375.00
IUUC-Sar-113435	Sorex araneus	92.06	3.00e-66	243.00
IUUC-Ssc-116388	Sus scrofa	92.24	3.00e-128	450.00
IUUC-Tsy-119439	Tarsius syrichta	92.66	4.00e-97	346.00
IUUC-Tbe-127417	Tupaia belangeri	68.14	5.00e-71	259.00
IUUC-Ttr-129212	Tursiops truncatus	92.24	3.00e-128	450.00
IUUC-Vpa-130153	Vicugna pacos	90.09	9.00e-125	439.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence