iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mlu-067561

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02023684

Gene Name

RNF125

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000012859.2	ENSMLUT00000012863.2	ENSMLUP00000011700.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	90.40	7.00e-93	336.00	IUUC-Hsa-046518
UBD/Alpha-Helix/UIM	90.40	7.00e-93	336.00	IUUC-Hsa-046518

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

FCRSCIATSL KSSKWTCPYC RAYLPSEGVP ATDVTRRMKS EFQNCAECGT LVCLSEMRAH 60
IRTCQKYIDK YGPLQELGET AARCVCPFCQ KELDEDSLLD HCINHHRSER RPVFCPLCRL 120

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Nucleotide Sequence
(Fasta)

TTCTGCCGCT CCTGTATTGC CACCAGTCTG AAGAGCAGCA AGTGGACCTG CCCTTACTGC 60
CGGGCGTACC TTCCTTCCGA AGGAGTCCCA GCCACGGATG TGACCAGAAG GATGAAATCA 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR008598--Di19_Zn_binding_dom
IPR034734--ZF_C2HC_RNF
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51803--ZF_C2HC_RNF

Pfam

PF05605--zf-Di19

Gene Ontology

GO:0000139--C:Golgi membrane
GO:0034098--C:VCP-NPL4-UFD1 AAA ATPase complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0039536--P:negative regulation of RIG-I signaling pathway
GO:0032480--P:negative regulation of type I interferon production
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001992	Ailuropoda melanoleuca	88.14	3.00e-93	333.00
IUUC-Aca-004839	Anolis carolinensis	62.01	4.00e-65	239.00
IUUC-Bta-012827	Bos taurus	87.57	5.00e-92	330.00
IUUC-Cja-018794	Callithrix jacchus	89.27	1.00e-93	335.00
IUUC-Cfa-021234	Canis familiaris	87.57	2.00e-92	331.00
IUUC-Cpo-022412	Cavia porcellus	83.62	4.00e-88	317.00
IUUC-Csa-023406	Chlorocebus sabaeus	89.83	1.00e-93	335.00
IUUC-Cho-024427	Choloepus hoffmanni	71.19	3.00e-70	256.00
IUUC-Dno-030085	Dasypus novemcinctus	88.14	8.00e-93	332.00
IUUC-Dor-030911	Dipodomys ordii	85.71	9.00e-51	192.00
IUUC-Ete-032469	Echinops telfairi	83.62	4.00e-88	317.00
IUUC-Eca-034352	Equus caballus	88.70	2.00e-93	334.00
IUUC-Eeu-034889	Erinaceus europaeus	72.32	5.00e-70	256.00
IUUC-Fca-036116	Felis catus	88.70	4.00e-93	333.00
IUUC-Hsa-046518	Homo sapiens	90.40	5.00e-94	336.00
IUUC-Itr-048344	Ictidomys tridecemlineatus	90.40	5.00e-95	339.00
IUUC-Laf-053363	Loxodonta africana	86.59	2.00e-91	328.00
IUUC-Meu-056101	Macropus eugenii	76.27	2.00e-76	278.00
IUUC-Mdo-062046	Monodelphis domestica	74.01	6.00e-78	283.00
IUUC-Mmu-063184	Mus musculus	82.86	3.00e-58	216.00
IUUC-Mpu-065708	Mustela putorius furo	84.18	3.00e-89	321.00
IUUC-Nle-069665	Nomascus leucogenys	87.42	7.00e-82	296.00
IUUC-Opr-070301	Ochotona princeps	71.19	3.00e-70	257.00
IUUC-Ocu-074562	Oryctolagus cuniculus	88.10	9.00e-64	234.00
IUUC-Oga-088958	Otolemur garnettii	89.27	3.00e-94	337.00
IUUC-Oar-089541	Ovis aries	88.70	6.00e-93	332.00
IUUC-Ptr-090989	Pan troglodytes	90.96	4.00e-95	340.00
IUUC-Pan-092372	Papio anubis	89.83	8.00e-94	336.00
IUUC-Pab-098718	Pongo abelii	72.88	1.00e-69	255.00
IUUC-Pca-100453	Procavia capensis	87.01	4.00e-91	327.00
IUUC-Pva-102931	Pteropus vampyrus	87.01	2.00e-91	327.00
IUUC-Rno-105771	Rattus norvegicus	83.71	1.00e-78	286.00
IUUC-Sha-107557	Sarcophilus harrisii	73.45	1.00e-79	288.00
IUUC-Sar-113435	Sorex araneus	90.48	3.00e-65	239.00
IUUC-Ssc-116388	Sus scrofa	88.70	4.00e-94	337.00
IUUC-Tsy-119439	Tarsius syrichta	89.27	4.00e-94	336.00
IUUC-Tbe-127417	Tupaia belangeri	66.44	3.00e-53	201.00
IUUC-Ttr-129212	Tursiops truncatus	88.70	9.00e-94	335.00
IUUC-Vpa-130153	Vicugna pacos	87.57	2.00e-92	331.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence